These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Bergauff MA, et al. (2010).||These studies suggest that diet is a major factor in determining urinary levoglucosan levels and recent dietary history needs to be taken into account for future work involving levoglucosan as a biomarker of wood smoke exposure.||diet||1,6-
||Study subjects||United States||urine||1,6-
|2.||Peng C, et al. (2016).||Normative Aging Study (NAS)||Among nondiabetics, short and medium-term exposures to PM2.5 particulate matter were associated with higher fasting blood glucose levels, and part of this association was mediated by ICAM1 gene promoter methylation.||Air Pollutants | Particulate Matter||Controls for disease:Diabetes Mellitus||United States||air, ambient | blood | blood buffy coat||Blood Glucose | ICAM1 | Particulate Matter||Details||glucose homeostasis|
|3.||Kelishadi R, et al. (2013).||Childhood and Adolescence Surveillance and Prevention of Adult Noncommunicable disease (CASPIAN)||Cadmium levels were considerably high in adolescents with and without metabolic syndrome, and levels had positive but nonsignificant association with some cardiometabolic risk factors and liver enzymes; the associations did not reach statistical significance, perhaps due to high levels of cadmium in both groups or because of the young age of participants.||Cadmium||Children | Controls for disease:Metabolic Syndrome | Subjects with disease:Metabolic Syndrome||Iran, Islamic Republic of||blood | serum||Blood Glucose | Cadmium | Cholesterol, HDL | Cholesterol, LDL | GOT1 | GPT | Triglycerides||Details||Metabolic Syndrome|
|4.||He K, et al. (2013).||Coronary Artery Risk Development in Young Adults (CARDIA) Study||Our results provide longitudinal human data suggesting that people with high mercury exposure in young adulthood may have elevated risk of diabetes later in life.||Mercury||Study subjects||United States||nail, toe | plasma||Blood Glucose | INS | Mercury||Details||Diabetes Mellitus | regulation of insulin secretion involved in cellular response to glucose stimulus|
|5.||Migliaccio CT, et al. (2009).||These results demonstrate that levoglucosan in the lungs is detectable in the urine of both mice and humans and that it is a good candidate as a biomarker of exposure to biomass smoke.||Particulate Matter | Tobacco Smoke Pollution||Children||United States||air | urine||1,6-