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Chemical Guanine

1–50 of 75 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1-methylguanine DNA dealkylation involved in DNA repair ALKBH2 [ALKBH2 protein results in increased DNA dealkylation involved in DNA repair] which results in decreased abundance of 1-methylguanine 1: Homo sapiens     1
2. 8-nitroguanine depurination Arsenicals | reactive nitrogen species metabolic process [[Arsenicals results in increased reactive nitrogen species metabolic process] which results in increased depurination] which results in increased abundance of 8-nitroguanine 1: Homo sapiens Urine   1
3. 8-nitroguanine DNA modification Asbestos, Amphibole [Asbestos, Amphibole results in increased DNA modification] which results in increased abundance of 8-nitroguanine 1: Homo sapiens Lung   1
4. 8-nitroguanine reactive nitrogen species metabolic process Arsenicals | depurination [[Arsenicals results in increased reactive nitrogen species metabolic process] which results in increased depurination] which results in increased abundance of 8-nitroguanine 1: Homo sapiens Urine   1
5. Acyclovir post-embryonic eye morphogenesis Acyclovir results in decreased post-embryonic eye morphogenesis 1: Rattus norvegicus Eye   1
6. Acyclovir membrane lipid catabolic process Quinolinic Acid Acyclovir inhibits the reaction [Quinolinic Acid results in increased membrane lipid catabolic process] 1: Rattus norvegicus Brain   1
7. aflatoxin-B1-N7-guanine glutathione transferase activity Aflatoxin B1 | sulforafan [sulforafan results in increased glutathione transferase activity] inhibits the reaction [Aflatoxin B1 results in increased abundance of aflatoxin-B1-N7-guanine] 1: Rattus norvegicus Liver   1
8. Azaguanine cell death Azaguanine results in increased cell death 1: Homo sapiens Lung | Cell Line, Tumor   1
9. Ganciclovir Sertoli cell proliferation Ganciclovir results in decreased Sertoli cell proliferation 1: Rattus norvegicus Sertoli Cells   1
10. Ganciclovir seminiferous tubule development Ganciclovir results in decreased seminiferous tubule development 1: Rattus norvegicus Seminiferous Tubules | Germ Cells   1
11. Ganciclovir negative regulation of male gonad development Ganciclovir results in increased negative regulation of male gonad development 1: Rattus norvegicus Testis   1
12. Ganciclovir germ cell development Ganciclovir results in decreased germ cell development 1: Rattus norvegicus Seminiferous Tubules | Germ Cells   1
13. Ganciclovir developmental process involved in reproduction Ganciclovir results in decreased developmental process involved in reproduction 1: Rattus norvegicus     1
14. Ganciclovir germ cell development Ganciclovir results in decreased germ cell development 1: Rattus norvegicus Testis   1
15. Ganciclovir Sertoli cell development Ganciclovir results in decreased Sertoli cell development 1: Rattus norvegicus Sertoli Cells   1
16. Guanine DNA-dependent DNA replication maintenance of fidelity Guanine metabolite results in decreased DNA-dependent DNA replication maintenance of fidelity 1: Homo sapiens     1
17. Guanine DNA-dependent DNA replication maintenance of fidelity REV1 REV1 protein inhibits the reaction [Guanine metabolite results in decreased DNA-dependent DNA replication maintenance of fidelity] 1: Homo sapiens     1
18. N7-(2,3,4-trihydroxybut-1-yl)-guanine DNA modification 1,3-butadiene [1,3-butadiene results in increased DNA modification] which results in increased abundance of N7-(2,3,4-trihydroxybut-1-yl)-guanine 1: Mus musculus Lung   1
19. O(6)-benzylguanine cell cycle mitozolomide [mitozolomide co-treated with O(6)-benzylguanine] results in decreased cell cycle 1: Homo sapiens Brain | Cell Line, Tumor
7 genes: CDKN1A | CDKN1B | CHEK1 | MLH1 | MSH2 | TP53 | TRP53 		1
20. O(6)-benzylguanine cell cycle Carmustine [Carmustine co-treated with O(6)-benzylguanine] results in decreased cell cycle 1: Homo sapiens Brain | Cell Line, Tumor
7 genes: CDKN1A | CDKN1B | CHEK1 | MLH1 | MSH2 | TP53 | TRP53 		1
21. O(6)-benzylguanine cell cycle temozolomide [temozolomide co-treated with O(6)-benzylguanine] results in decreased cell cycle 1: Homo sapiens Brain | Cell Line, Tumor
7 genes: CDKN1A | CDKN1B | CHEK1 | MLH1 | MSH2 | TP53 | TRP53 		1
22. O(6)-benzylguanine apoptotic process Dacarbazine O(6)-benzylguanine inhibits the reaction [Dacarbazine results in increased apoptotic process] 1: Mus musculus Intestine, Small | Epithelium
5 genes: BAX | BCL2 | CHEK1 | TP53 | TRP53 		1
23. O(6)-benzylguanine positive regulation of cell death fotemustine O(6)-benzylguanine promotes the reaction [fotemustine results in increased positive regulation of cell death] 1: Homo sapiens Neuroglia | Cell Line, Tumor
2 genes: CDKN1A | CDKN1B 		1
24. O-(6)-methylguanine DNA modification 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased DNA modification] which results in increased abundance of O-(6)-methylguanine 1: Mus musculus Lung   1
25. O-(6)-methylguanine DNA modification 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 7,8-dihydromethysticin 7,8-dihydromethysticin inhibits the reaction [[4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased DNA modification] which results in increased abundance of O-(6)-methylguanine] 1: Mus musculus Lung   1
26. O-(6)-methylguanine DNA modification 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol [4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol results in increased DNA modification] which results in increased abundance of O-(6)-methylguanine 1: Mus musculus Lung   1
27. Pemetrexed negative regulation of DNA repair resveratrol [Pemetrexed co-treated with resveratrol] affects negative regulation of DNA repair 1: Homo sapiens Lung | Cell Line, Tumor   1
28. Pemetrexed negative regulation of DNA repair MAP2K6 | resveratrol MAP2K6 protein mutant form inhibits the reaction [[Pemetrexed co-treated with resveratrol] affects negative regulation of DNA repair] Lung | Cell Line, Tumor   1
29. Pemetrexed apoptotic process Cisplatin [Pemetrexed co-treated with Cisplatin] results in increased apoptotic process 1: Homo sapiens Epithelium | Cell Line, Tumor
12 genes: BCL2 | BID | CFLAR | DDIT3 | FAS | IL1A | MAP2K6 | TNFAIP3 | TNFRSF10B | TNFRSF9 | TP53 | TRAF1 		1
30. Pemetrexed positive regulation of cell death Pemetrexed affects positive regulation of cell death 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: CDKN1A | FAS 		1
31. Pemetrexed apoptotic process Acetylcysteine | Cisplatin | Valproic Acid Acetylcysteine inhibits the reaction [Valproic Acid promotes the reaction [[Pemetrexed co-treated with Cisplatin] results in increased apoptotic process]] 1: Homo sapiens Epithelium | Cell Line, Tumor
12 genes: BCL2 | BID | CFLAR | DDIT3 | FAS | IL1A | MAP2K6 | TNFAIP3 | TNFRSF10B | TNFRSF9 | TP53 | TRAF1 		1
32. Pemetrexed drug transmembrane transport Fluorodeoxyuridylate [Pemetrexed results in decreased drug transmembrane transport] which results in decreased export of Fluorodeoxyuridylate 1: Homo sapiens HEK293 Cells | Cell-Free System   1
33. Pemetrexed cell proliferation Folic Acid Folic Acid affects the reaction [Pemetrexed affects cell proliferation] 1: Homo sapiens Cell Line
6 genes: ALK | BCL2 | ERCC1 | FPGS | IL1A | TP53 		1
34. Pemetrexed cell cycle Cisplatin | Valproic Acid Valproic Acid promotes the reaction [[Pemetrexed co-treated with Cisplatin] results in decreased cell cycle] 1: Homo sapiens Epithelium | Cell Line, Tumor
4 genes: CCND1 | CDKN1A | DDIT3 | TP53 		1
35. Pemetrexed positive regulation of cell death Methotrexate Methotrexate inhibits the reaction [Pemetrexed results in increased positive regulation of cell death] 1: Homo sapiens MCF-7 Cells
2 genes: CDKN1A | FAS 		1
36. Pemetrexed cell cycle gemcitabine [Pemetrexed co-treated with gemcitabine] results in decreased cell cycle 1: Homo sapiens Pancreas | Cell Line, Tumor
4 genes: CCND1 | CDKN1A | DDIT3 | TP53 		1
37. Pemetrexed apoptotic process Cisplatin | Valproic Acid Valproic Acid promotes the reaction [[Pemetrexed co-treated with Cisplatin] results in increased apoptotic process] 1: Homo sapiens Epithelium | Cell Line, Tumor
12 genes: BCL2 | BID | CFLAR | DDIT3 | FAS | IL1A | MAP2K6 | TNFAIP3 | TNFRSF10B | TNFRSF9 | TP53 | TRAF1 		1
38. Pemetrexed positive regulation of p38MAPK cascade resveratrol Pemetrexed inhibits the reaction [resveratrol affects positive regulation of p38MAPK cascade] 1: Homo sapiens Lung | Cell Line, Tumor   1
39. Pemetrexed drug transmembrane transport Pemetrexed results in decreased drug transmembrane transport 1: Homo sapiens HEK293 Cells | Cell-Free System   1
40. Pemetrexed negative regulation of cell proliferation Pemetrexed affects negative regulation of cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor
8 genes: BCL2 | CDKN1A | CXCL8 | IL1A | IL1RL1 | NPM1 | TNFRSF9 | TP53 		1
41. Pemetrexed cell proliferation gemcitabine Pemetrexed promotes the reaction [gemcitabine results in decreased cell proliferation] 1: Homo sapiens Pancreas | Cell Line, Tumor
6 genes: ALK | BCL2 | ERCC1 | FPGS | IL1A | TP53 		1
42. Pemetrexed cell cycle Cisplatin | vorinostat vorinostat promotes the reaction [[Pemetrexed co-treated with Cisplatin] results in decreased cell cycle] 1: Homo sapiens Epithelium | Cell Line, Tumor
4 genes: CCND1 | CDKN1A | DDIT3 | TP53 		1
43. Pemetrexed apoptotic process Acetylcysteine | Cisplatin | vorinostat Acetylcysteine inhibits the reaction [vorinostat promotes the reaction [[Pemetrexed co-treated with Cisplatin] results in increased apoptotic process]] 1: Homo sapiens Epithelium | Cell Line, Tumor
12 genes: BCL2 | BID | CFLAR | DDIT3 | FAS | IL1A | MAP2K6 | TNFAIP3 | TNFRSF10B | TNFRSF9 | TP53 | TRAF1 		1
44. Pemetrexed cell proliferation Aminoimidazole Carboxamide | SLC46A1 | Thymidine [Aminoimidazole Carboxamide co-treated with Thymidine] affects the reaction [[SLC46A1 protein results in increased susceptibility to Pemetrexed] which affects cell proliferation] 1: Homo sapiens CHO Cells
6 genes: ALK | BCL2 | ERCC1 | FPGS | IL1A | TP53 		1
45. Pemetrexed apoptotic process benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | Cisplatin benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Pemetrexed co-treated with Cisplatin] results in increased apoptotic process] 1: Homo sapiens Epithelium | Cell Line, Tumor
12 genes: BCL2 | BID | CFLAR | DDIT3 | FAS | IL1A | MAP2K6 | TNFAIP3 | TNFRSF10B | TNFRSF9 | TP53 | TRAF1 		1
46. Pemetrexed apoptotic process Acetylcysteine | Cisplatin | Valproic Acid Acetylcysteine inhibits the reaction [[Pemetrexed co-treated with Cisplatin] promotes the reaction [Valproic Acid results in increased apoptotic process]] 1: Homo sapiens Epithelium | Cell Line, Tumor
12 genes: BCL2 | BID | CFLAR | DDIT3 | FAS | IL1A | MAP2K6 | TNFAIP3 | TNFRSF10B | TNFRSF9 | TP53 | TRAF1 		1
47. Pemetrexed cell proliferation Pemetrexed affects cell proliferation 1: Homo sapiens Cell Line
6 genes: ALK | BCL2 | ERCC1 | FPGS | IL1A | TP53 		1
48. Pemetrexed positive regulation of cell death ABCC11 ABCC11 mRNA inhibits the reaction [Pemetrexed results in increased positive regulation of cell death] 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: CDKN1A | FAS 		1
49. Pemetrexed cell proliferation Cisplatin | Valproic Acid [Valproic Acid co-treated with Cisplatin co-treated with Pemetrexed] results in decreased cell proliferation 2: Homo sapiens | Mus musculus  
6 genes: ALK | BCL2 | ERCC1 | FPGS | IL1A | TP53 		1
50. Pemetrexed response to antineoplastic agent Methotrexate [Methotrexate results in decreased response to antineoplastic agent] which results in decreased susceptibility to Pemetrexed 1: Homo sapiens MCF-7 Cells   1
1–50 of 75 results.
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