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Chemical Heterocyclic Compounds, 1-Ring

These are exposure studies associated with the chemical and all of its children.

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1–50 of 204 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Loh MM, et al. (2007). In this study we compared cancer risks from organic hazardous air pollutants (HAPs) based on total personal exposure summed across different microenvironments and exposure pathways. 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1,3-butadiene | 1,3-dichloro-1-propene | 4-dichlorobenzene | Acetaldehyde | anthracene | benz(a)anthracene | Benzene | Benzo(a)pyrene | benzo(b)fluoranthene | Carbon Tetrachloride | Chloroform | chrysene | Dioxins | Ethylene Dibromide | ethylene dichloride | fluoranthene | Formaldehyde | indeno(1,2,3-cd)pyrene | Methylene Chloride | naphthalene | phenanthrene | Polycyclic Aromatic Hydrocarbons | pyrene | Tetrachloroethylene | Trichloroethylene | Vinyl Chloride Study subjects United States 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1,3-butadiene | 1,3-dichloro-1-propene | 4-dichlorobenzene | Acetaldehyde | anthracene | benz(a)anthracene | Benzene | Benzo(a)pyrene | benzo(b)fluoranthene | Carbon Tetrachloride | Chloroform | chrysene | Dioxins | Ethylene Dibromide | ethylene dichloride | fluoranthene | Formaldehyde | indeno(1,2,3-cd)pyrene | Methylene Chloride | naphthalene | phenanthrene | Polycyclic Aromatic Hydrocarbons | pyrene | Tetrachloroethylene | Trichloroethylene | Vinyl Chloride Details Neoplasms
2. Aquilina NJ, et al. (2010). Measurement and Modelling of Air Toxic Concentrations for Health Effect Studies Project (MATCH) The objective of this study was to analyse environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbon (PAH) metabolites in urine samples of non-occupationally exposed non-smoker adult subjects and to establish relationships between airborne exposures and urinary concentrations in order to assess the suitability of the studied metabolites as biomarkers of PAH and ETS, study the use of 3-ethenypyridine as ETS tracer, and link ETS scenarios with exposures to carcinogenic PAH and volatile organic compounds. tobacco 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 3-vinylpyridine | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | coronene | fluoranthene | fluorene | hydroxycotinine | indeno(1,2,3-cd)pyrene | naphthalene | Nicotine | phenanthrene | Polycyclic Aromatic Hydrocarbons | pyrene Study subjects United Kingdom urine 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 3-vinylpyridine | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | coronene | fluoranthene | fluorene | hydroxycotinine | indeno(1,2,3-cd)pyrene | naphthalene | Nicotine | phenanthrene | Polycyclic Aromatic Hydrocarbons | pyrene Details
3. Turyk ME, et al. (2007). National Health and Nutrition Examination Survey (NHANES) In the adult participants of NHANES from 1999 to 2002, total thyroxine was negatively associated with serum dioxin-like toxic equivalents in a dose-dependent fashion, with stronger associations in women than men. age | sex 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3,4,7,8-pentachlorodibenzofuran | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Benzofurans | dibenzodioxin | Dichlorodiphenyl Dichloroethylene | Dioxins and Dioxin-like Compounds | Hydrocarbons, Chlorinated | PCB 180 | Polychlorinated Biphenyls Study subjects United States serum 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3,4,7,8-pentachlorodibenzofuran | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Benzofurans | dibenzodioxin | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
4. Dodson RE, et al. (2015). California Household Exposure Study (CAHES) We collected house dust and indoor air samples in 49 California homes and analyzed for 76 semivolatile organic compounds-phthalates, polybrominated diphenyl ethers, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, and pesticides. 1,2,5,6-dibenzanthracene | 1-methylphenanthrene | 1-nitropyrene | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4'-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | 2-methylphenanthrene | 2-phenylphenol | 4,6-dimethyldibenzothiophene | 4-nitrotoluene | acenaphthene | acenaphthylene | alachlor | Aldrin | anthracene | Atrazine | bendiocarb | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(j)fluoranthene | benzo(k)fluoranthene | benzothiophene | butylbenzyl phthalate | Carbaryl | Carbofuran | Chlordan | Chlorpyrifos | chrysene | cyanazine | cypermethrin | DDT | Diazinon | dibenzo(a,e)pyrene | dibenzothiophene | Dibutyl Phthalate | Dichlorodiphenyldichloroethane | Dichlorodiphenyl Dichloroethylene | Dicofol | dicyclohexyl phthalate | Dieldrin | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | di-n-hexyl phthalate | di-n-octyl phthalate | di-n-pentyl phthalate | di-n-propylphthalate | dioctyl adipate | Endrin | fluoranthene | fluorene | Heptachlor | indeno(1,2,3-cd)pyrene | Lindane | Malathion | Methoxychlor | Methyl Parathion | metolachlor | nitrofen | Parathion | pentabromodiphenyl ether | Permethrin | phenanthrene | Phenanthrenes | Piperonyl Butoxide | prometone | Propoxur | pyrene | Simazine | tetrachloroisophthalonitrile | Trifluralin | tris(2,3-dibromopropyl)phosphate United States dust 1,2,5,6-dibenzanthracene | 1-methylphenanthrene | 1-nitropyrene | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4'-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | 2-methylphenanthrene | 2-phenylphenol | 4,6-dimethyldibenzothiophene | 4-nitrotoluene | acenaphthene | acenaphthylene | alachlor | Aldrin | anthracene | Atrazine | bendiocarb | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(j)fluoranthene | benzo(k)fluoranthene | benzothiophene | butylbenzyl phthalate | Carbaryl | Carbofuran | Chlordan | Chlorpyrifos | chrysene | cyanazine | cypermethrin | DDT | Diazinon | dibenzo(a,e)pyrene | dibenzothiophene | Dibutyl Phthalate | Dichlorodiphenyldichloroethane | Dichlorodiphenyl Dichloroethylene | Dicofol | dicyclohexyl phthalate | Dieldrin | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | di-n-hexyl phthalate | di-n-octyl phthalate | di-n-pentyl phthalate | di-n-propylphthalate | dioctyl adipate | Endrin | fluoranthene | fluorene | Heptachlor | indeno(1,2,3-cd)pyrene | Lindane | Malathion | Methoxychlor | Methyl Parathion | metolachlor | nitrofen | Parathion | pentabromodiphenyl ether | Permethrin | phenanthrene | Phenanthrenes | Piperonyl Butoxide | prometone | Propoxur | pyrene | Simazine | tetrachloroisophthalonitrile | Trifluralin | tris(2,3-dibromopropyl)phosphate Details
5. Kalkbrenner AE, et al. (2018). Autism Genetic Resource Exchange (AGRE) Some air toxics were associated with autism spectrum disorder risk and severity, including some traffic-related air pollutants and newly-reported associations, but other previously reported associations with metals and volatile organic compounds were not reproducible. 1,4-dioxane | 4,4'-diphenylmethane diisocyanate | 4-dichlorobenzene | benzidine | bromoform | Carbon Disulfide | chlorobenzene | Dibenzofurans | methyl tert-butyl ether | propionaldehyde | Urethane Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder United States Details Autism Spectrum Disorder
6. Aszyk J, et al. (2017). A gas chromatography-electron ionization-mass spectometry method was developed and validated for the simultaneous determination of 46 commonly used flavour additives in e-liquids. 1-hexanol | 3,4-dihydrocoumarin | 3-hexen-1-ol | 4-Butyrolactone | alpha-terpineol | anisyl acetate | benzaldehyde | benzyl acetate | Benzyl Alcohol | citronellol | decan-4-olide | decanaldehyde | ethyl hexanoate | Eugenol | Furaldehyde | furfuryl alcohol | isoamyl acetate | limonene | linalyl acetate | methyl acetate | n-pentanol | raspberry ketone Poland e-cigarette, liquid 1-hexanol | 3,4-dihydrocoumarin | 3-hexen-1-ol | 4-Butyrolactone | alpha-terpineol | anisyl acetate | benzaldehyde | benzyl acetate | Benzyl Alcohol | citronellol | decan-4-olide | decanaldehyde | ethyl hexanoate | Eugenol | Furaldehyde | furfuryl alcohol | isoamyl acetate | limonene | linalyl acetate | methyl acetate | n-pentanol | raspberry ketone Details
7. Woodruff TJ, et al. (2011). National Health and Nutrition Examination Survey (NHANES) Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Pregnant females | Study subjects United States blood | serum | urine 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Details
8. Johnson NM, et al. (2010). Findings suggest that the incidence and level of aflatoxins and polycyclic aromatic hydrocarbon exposure was less than that observed in a high-risk population; however, participants consuming higher amounts of foods prone to aflatoxin contamination may be more vulnerable to exposure and interactions with other environmental/biological factors (i.e., hepatitis C virus). diet 1-hydroxypyrene | Aflatoxin M1 Study subjects United States urine 1-hydroxypyrene | Aflatoxin M1 Details
9. Meeker JD, et al. (2004). In the present study we found associations between urinary metabolites of contemporary-use insecticides and decreased sperm concentration and motility in humans. 1-naphthol | 3,5,6-trichloro-2-pyridinol | Insecticides Subjects with disease:Infertility, Male United States semen | urine 1-naphthol | 3,5,6-trichloro-2-pyridinol Details Infertility, Male | spermatogenesis | sperm motility
10. Ayotte P, et al. (2005). In summary, we found no relation between biomarkers of organochlorine exposure and markers of hepatic enzyme induction in this highly exposed group of fish eaters from the Lower North Shore of the St. Lawrence River. Our results suggest that smoking induces liver CYP1A2 activity, which in turn alters porphyrin metabolism and increases the biotransformation of mono-ortho polychlorinated biphenyls. tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Hydrocarbons, Chlorinated | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Study subjects Canada plasma | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Coproporphyrins | Dichlorodiphenyl Dichloroethylene | Glucaric Acid | Hexachlorobenzene | Hydrocarbons, Chlorinated | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls | Uroporphyrins Details enzyme activator activity
11. Patel CJ, et al. (2012). National Health and Nutrition Examination Survey (NHANES) We screened for correlation between environmental factors and lipid levels, utilizing four independent surveys with information on 188 environmental factors from the Centers of Disease Control, National Health and Nutrition Examination Survey, collected between 1999 and 2006. age | body mass index | race | sex | socioeconomic status 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2,4,4',5-tetrachlorobiphenyl | 2-hydroxyfluorene | alpha-Tocopherol | Ascorbic Acid | beta Carotene | Cotinine | Cryptoxanthins | Fluorenes | Folic Acid | gamma-Tocopherol | Heptachlor Epoxide | Iron | lycopene | Mercury | nonachlor | oxychlordane | retinol palmitate | retinyl stearate | Vitamin A | Vitamin D Study subjects United States Details cholesterol metabolic process | triglyceride metabolic process
12. Robinson O, et al. (2015). INfancia y Medio Ambiente (INMA) Project In summary, the correlation analysis presented here of multiple environmental exposures among pregnant women provide a first picture of the structure of the exposome during the crucial in utero period. 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Pregnant females Spain air | blood, cord | colostrum | serum | urine | water 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Details
13. Dallaire R, et al. (2009). Exposure to several polyhalogenated compounds was associated with modifications of the thyroid parameters in adult Inuit, mainly by reducing total triiodothyronine and thyroxine-binding globulin circulating concentrations. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Dioxins | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hydrocarbons, Chlorinated | PCB 180 | Pentachlorophenol | perfluorooctane sulfonic acid | Polybrominated Biphenyls | Polychlorinated Biphenyls | Selenium Study subjects Canada blood | plasma | serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Dioxins | hexabrominated diphenyl ether 153 | Hexachlorobenzene | PCB 180 | Pentachlorophenol | perfluorooctane sulfonic acid | Polychlorinated Biphenyls | Selenium | SERPINA7 | Thyroxine | Triiodothyronine | TSHB Details regulation of thyroid-stimulating hormone secretion | thyroid hormone metabolic process
14. Arcury TA, et al. (2007). In this investigation we documented the pesticide urinary metabolite levels of farmworker children in North Carolina, determined the number of different metabolites detected for each child, and delineated risk factors associated with the number of metabolites. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | 3-phenoxybenzoic acid | acetochlor | Atrazine | Chlorpyrifos | Coumaphos | DEET | Diazinon | isazophos | Malathion | metolachlor | Parathion | pirimiphos methyl Children United States urine 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | 3-phenoxybenzoic acid | acetochlor | Atrazine | Chlorpyrifos | Coumaphos | DEET | Diazinon | isazophos | Malathion | metolachlor | Parathion | pirimiphos methyl Details
15. Bakke B, et al. (2009). Agricultural Health Study (AHS) We measured the exposure to atrazine and selected non-persistent pesticides among corn farmers during a growing season; urinary atrazine mercapturate levels in farmers were largely driven by recent application of atrazine; therefore, the amount of atrazine applied is likely to provide valid surrogates of atrazine exposure in epidemiologic studies. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | acetochlor | Atrazine | Chlorpyrifos | Coumaphos | Diazinon | Malathion | Methyl Parathion | metolachlor | pirimiphos methyl | Pyrethrins Workers United States urine 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol | 3-phenoxybenzoic acid | acetochlor mercapturate | atrazine mercapturate | chlorferron | Diazinon | Malathion | Methyl Parathion | metolachlor | pirimiphos methyl Details
16. Goldner WS, et al. (2010). Agricultural Health Study (AHS) These data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldrin | Atrazine | Benomyl | butylate | Captan | Carbaryl | Carbon Disulfide | Carbon Tetrachloride | Chlordan | chlorimuron ethyl | Chlorpyrifos | cyanazine | DDT | Diazinon | Dicamba | Dichlorvos | EPTC | Fonofos | Fungicides, Industrial | glyphosate | Heptachlor | Hydrocarbons, Chlorinated | imazethapyr | Insecticides | Lindane | Malathion | mancozeb | Maneb | metalaxyl | methyl bromide | metolachlor | metribuzin | Paraquat | Parathion | pendimethalin | Petroleum | terbufos | tetrachloroisophthalonitrile | Trifluralin Study subjects United States Details Agricultural Workers' Diseases | Hyperthyroidism | Hypothyroidism
17. Waggoner JK, et al. (2013). Agricultural Health Study (AHS) In this large cohort of male farmers, pesticide use, in addition to farm machinery use, was associated with fatal injury. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | metribuzin | Paraquat | Ziram Workers United States Details Death
18. Saldana TM, et al. (2007). Agricultural Health Study (AHS) These findings suggest that activities involving exposure to agricultural pesticides during the first trimester of pregnancy may increase the risk of gestational diabetes mellitus. 2,4,5-Trichlorophenoxyacetic Acid | Atrazine | butylate | Carbofuran | Diazinon | fenoprop | Pesticides | Phorate Mothers United States Details Agricultural Workers' Diseases | Diabetes, Gestational
19. Kamel F, et al. (2007). Agricultural Health Study (AHS) This study suggests that exposure to certain pesticides may increase Parkinson's disease risk. 2,4,5-Trichlorophenoxyacetic Acid | Benomyl | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | Dicamba | Ethylene Dibromide | Lindane | mancozeb | Maneb | methyl bromide | Paraquat | pendimethalin | Pesticides | Phorate | tetrachloroisophthalonitrile Study subjects | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
20. Hoppin JA, et al. (2007). Agricultural Health Study (AHS) These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence. 2,4,5-Trichlorophenoxyacetic Acid | Carbaryl | Carbofuran | chlorimuron ethyl | DDT | Diazinon | Dichlorvos | fenoprop | Heptachlor | Malathion | Permethrin Workers United States Details Agricultural Workers' Diseases | Bronchitis, Chronic
21. Carreón T, et al. (2005). Upper Midwest Health Study (UMHS) Results show that exposure to pesticides was not associated with an increased risk of intracranial gliomas in women. 2,4-Dichlorophenoxyacetic Acid | 2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide | alachlor | Aniline Compounds | Arsenicals | Atrazine | bentazone | Benzoic Acid | Carbamates | cyanazine | DDT | Diazinon | Dicamba | Hydrocarbons, Chlorinated | imazethapyr | Inorganic Chemicals | Malathion | metolachlor | Organophosphates | pendimethalin | Pesticides | Triazines | Trifluralin Controls for disease:Glioma | Subjects with disease:Glioma United States Details Glioma
22. Munger R, et al. (1997). We conclude that communities in southern Iowa with drinking water supplies contaminated with herbicides have elevated rates of intrauterine growth retardation compared to neighboring communities with different water supplies. 2,4-Dichlorophenoxyacetic Acid | 2-xylene | 3-xylene | 4-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane Pregnant females United States water, drinking 2,4-Dichlorophenoxyacetic Acid | 2-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane | Xylenes Details Fetal Growth Retardation
23. Swan SH, et al. (2003). Study for Future Families (SFF) This is the first population-based study to demonstrate links between specific biomarkers of environmental exposures and biomarkers of male reproduction in humans. 2,4-Dichlorophenoxyacetic Acid | acetochlor | alachlor | Atrazine | DEET | Diazinon | Malathion | metolachlor Controls for disease:Infertility, Male | Subjects with disease:Infertility, Male United States semen 2,4-Dichlorophenoxyacetic Acid | acetochlor | alachlor | Atrazine | DEET | Diazinon | Malathion | metolachlor Details Infertility, Male
24. Hoppin JA, et al. (2017). Agricultural Health Study (AHS) We evaluated the association of currently used pesticides with allergic and non-allergic wheeze among male farmers, and our results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects. 2,4-Dichlorophenoxyacetic Acid | acetochlor | Atrazine | bentazone | Carbaryl | Chlorpyrifos | clomazone | clopyralid | cyfluthrin | Dicamba | Dimethoate | Disulfoton | fenoxaprop ethyl | fluazifop-butyl | glyphosate | Herbicides | imazaquin | Insecticides | Malathion | mesotrione | metolachlor | N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide | nicosulfuron | Permethrin | Petroleum | Picloram | Pyrethrins | Rodenticides | Simazine | triclopyr | Trifluralin | Warfarin Workers United States Details Respiratory Sounds | Rhinitis, Allergic
25. Hoppin JA, et al. (2002). Agricultural Health Study (AHS) Prevalence of wheeze was associated with individual pesticides independent of animals, crops, and grains. disease 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldicarb | aluminum phosphide | Atrazine | Benomyl | butylate | Captan | Carbaryl | Carbofuran | chlorimuron ethyl | Chlorpyrifos | Coumaphos | cyanazine | Diazinon | Dicamba | Dichlorvos | EPTC | Fonofos | glyphosate | imazethapyr | Lindane | Malathion | Maneb | metalaxyl | metolachlor | metribuzin | Paraquat | Parathion | pendimethalin | Permethrin | Petroleum | Phorate | terbufos | tetrachloroisophthalonitrile | Trichlorfon | Trifluralin | Ziram Subjects with disease:Asthma | Subjects with disease:Ige Responsiveness, Atopic | Workers United States Details Agricultural Workers' Diseases | Respiratory Sounds
26. Hoppin JA, et al. (2008). Agricultural Health Study (AHS) These findings suggest that pesticides may contribute to atopic asthma, but not nonatopic asthma, among farm women. 2,4-Dichlorophenoxyacetic Acid | Carbamates | Carbaryl | Coumaphos | DDT | glyphosate | Hydrocarbons, Chlorinated | Malathion | metalaxyl | Organophosphates | Parathion | Permethrin | Pesticides | Phorate Study subjects United States Details Agricultural Workers' Diseases | Asthma
27. Thomas KW, et al. (2010). Agricultural Health Study (AHS) This study provides information on pesticide exposures and possible exposure determinants for several application methods commonly used by farmers and will provide information to assess and refine exposure classification; results may also be of use in pesticide safety education for reducing exposures to pesticide applicators. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos Workers United States air, personal | body region | hand | urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol | Chlorpyrifos Details
28. Thomas KW, et al. (2010). Agricultural Health Study (AHS) This study provides a direct assessment of the intensity score algorithm within the Agricultural Health Study cohort for several application methods. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos Workers United States urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol Details
29. Coble J, et al. (2011). Agricultural Health Study (AHS) Revised weighting factors in a pesticide exposure intensity algorithm were developed for use in epidemiologic analyses for the Agricultural Health Study by using exposure monitoring data from two monitoring substudies in combination with the world's exposure literature and Pesticide Handlers Exposure Database. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos Workers United States urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol Details
30. Mandel JS, et al. (2005). The results of the study showed that exposure to farm family members can be quantified using biological markers of exposure and the exposure was variable by chemical largely, though not exclusively, determined by the degree of direct contact with the application process. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos | Herbicides Children | Study subjects | Workers United States urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol | Herbicides Details
31. Aszyk J, et al. (2017). Liquid chromatography-tandem mass spectrometry with electrospray ionization methods were developed for the simultaneous determination of 42 flavouring compounds and nicotine in liquids for e-cigarettes. 2,5-dimethylpyrazine | 2,6-lutidine | 2-acetylpyrrole | 5-methyl-2-furfural | benzyl acetate | cyclotene | diethyl succinate | ethyl acetoacetate | ethyl lactate | ethyl maltol | ethyl vanillin | furaneol | gamma-valerolactone | linalool | maltol | Menthol | menthone | methyl cinnamate | methylheptenone | methyl salicylate | Nicotine | pyridine | tetramethylpyrazine | vanillin Poland e-cigarette 2,5-dimethylpyrazine | 2,6-lutidine | 2-acetylpyrrole | 5-methyl-2-furfural | benzyl acetate | cyclotene | diethyl succinate | ethyl acetoacetate | ethyl lactate | ethyl maltol | ethyl vanillin | furaneol | gamma-valerolactone | linalool | maltol | Menthol | menthone | methyl cinnamate | methylheptenone | methyl salicylate | Nicotine | pyridine | tetramethylpyrazine | vanillin Details
32. Kim D, et al. (2013). Among 21 single-nucleotide polymorphisms of CYP1A1, CYP1A2, N-acetyltransferases and UDP-glucuronide transferases investigated in this study, genotypic groups of CYP1A1/T6235C (MSP I) and CYP1A2/-2467delT showed significant differences in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine excretion (P < 0.05). genetics 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Study subjects Korea, Republic of urine 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Details
33. Le NT, et al. (2016). Health Professionals Follow-up Study (HPFS) | Nurses' Health Study (NHS) Results from these two large prospective cohort studies do not support the hypothesis that higher intake of heterocyclic amine intake per se substantially increases risk of colorectal cancer. However, we observed positive association between 2-amino-1-methyl-6-phenylimidazo pyridine from red meat, but not from white meat, and proximal colon cancers. 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine Workers United States Details Colorectal Neoplasms
34. Beard JD, et al. (2013). Agricultural Health Study (AHS) Our study adds further evidence that high level pesticide exposure, such as pesticide poisoning, is associated with increased risk of depression and sets a lower bound on the level of exposure related to depression, thereby providing reassurance that the moderate levels of pesticide exposure experienced by farmers' wives likely do not increase risk. age | tobacco 2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide | Carbamates | Herbicides | metalaxyl | Permethrin | Pesticides | Triazines Study subjects United States Details Agricultural Workers' Diseases | Depressive Disorder
35. Lu C, et al. (2006). We were able to demonstrate that an organic diet provides a dramatic and immediate protective effect against exposures to organophosphorus pesticides that are commonly used in agricultural production. diet 2-isopropyl-6-methyl-4-pyrimidinol | 3,5,6-trichloro-2-pyridinol | chlorferron | Malathion | pirimiphos methyl Children United States urine 2-isopropyl-6-methyl-4-pyrimidinol | 3,5,6-trichloro-2-pyridinol | chlorferron | Malathion | pirimiphos methyl Details
36. Mitro SD, et al. (2016). National Health and Nutrition Examination Survey (NHANES) Our analysis shows that exposure to non-ortho polychlorinated biphenyls and toxic equivalency was associated with increased leukocyte telomere length in our study population of U.S. adults, contributing population-level findings to the evidence that exposure to environmental contaminants may influence telomere regulation. race 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Dioxins | Furans | Polychlorinated Biphenyls Controls for disease:Neoplasms | Subjects with disease:Neoplasms | Study subjects United States serum Polychlorinated Biphenyls Details regulation of telomere maintenance
37. Smarr MM, et al. (2017). Longitudinal Investigation of Fertility and the Environment Study (LIFE) Higher quartiles of preconception urinary concentrations of methyl paraben and ethyl paraben among female partners were associated with reduced couple fecundity in partner-specific and couple-based exposure models. sex 4-hydroxybenzoic acid | Anti-Infective Agents | benzylparaben | butylparaben | ethyl-p-hydroxybenzoate | heptylparaben | methylparaben | Parabens | propylparaben | protocatechuic acid | triclocarban | Triclosan Study subjects United States urine 4-hydroxybenzoic acid | benzylparaben | butylparaben | Creatinine | ethyl-p-hydroxybenzoate | heptylparaben | methylparaben | propylparaben | protocatechuic acid | triclocarban | Triclosan Details Infertility, Female | reproductive process
38. Farsalinos KE, et al. (2015). In this study, electronic cigarette liquids were evaluated for the presence of selected tobacco-derived chemicals. 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Acetaldehyde | Formaldehyde | Nicotine | Nitrates | Nitrosamines | N'-nitrosonornicotine | Phenols Greece|United States cigarette | e-cigarette, liquid 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Acetaldehyde | Formaldehyde | Nicotine | Nitrates | Nitrosamines | N'-nitrosonornicotine | Phenols Details
39. Dodson RE, et al. (2012). Common products contain complex mixtures of Endocrine-disrupting compounds and asthma-related compounds. 4-nonylphenol | 4-tert-octylphenol | benzophenone | benzyl acetate | bisphenol A | butylbenzyl phthalate | butylparaben | decamethylcyclopentasiloxane | Dibutyl Phthalate | dicyclohexyl phthalate | diethanolamine | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisononyl phthalate | di-n-hexyl phthalate | di-n-octyl phthalate | di-n-propylphthalate | Ethanolamine | ethyl-p-hydroxybenzoate | Eugenol | galaxolide | limonene | linalool | methyleugenol | methylionone | methylparaben | methyl salicylate | musk ketone | musk xylene | n-butoxyethanol | octamethylcyclotetrasiloxane | octylmethoxycinnamate | oxybenzone | phenoxyethanol | Phenyl Ethers | Phenylethyl Alcohol | pichtosin | triclocarban | Triclosan United States air freshener | air freshener, car | baking soda | bar soap | body lotion | body wash | Borax | car interior cleaner | carpet cleaner | cat litter | conditioner | deodorant | diaper | dish liquid | dishwasher detergent | dryer sheet | fabric refresher | facial cleanser | facial lotion | floor cleaner | foundation | fragrance or perfume | glass cleaner | hair gel | hair spray or mousse or gel | hand sanitizer | hand soap | laundry bleach | laundry detergent | lip balm | lipstick | mascara | nail polish | pillow protector | polish or wax | scrubbing powder | shampoo | shaving cream | shower curtain, vinyl | stain remover | sunscreen | sunscreen composite | surface cleaner | toilet bowl cleaner | toothpaste | tub and tile cleaner | wet mop 4-nonylphenol | 4-tert-octylphenol | benzophenone | benzyl acetate | bisphenol A | butylbenzyl phthalate | butylparaben | decamethylcyclopentasiloxane | Dibutyl Phthalate | dicyclohexyl phthalate | diethanolamine | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisononyl phthalate | di-n-hexyl phthalate | di-n-octyl phthalate | di-n-propylphthalate | Ethanolamine | ethyl-p-hydroxybenzoate | Eugenol | galaxolide | limonene | linalool | methyleugenol | methylionone | methylparaben | methyl salicylate | musk ketone | musk xylene | n-butoxyethanol | octamethylcyclotetrasiloxane | octylmethoxycinnamate | oxybenzone | phenoxyethanol | Phenyl Ethers | Phenylethyl Alcohol | pichtosin | triclocarban | Triclosan Details
40. Adad LM, et al. (2015). In this study, we determined the mutagenic and cell death potential of pesticides through the increased frequency of micronuclei and other nuclear abnormalities in exposed individuals abamectin | copper oxychloride | Dimethoate | glyphosate | Methyl Parathion | Triazines Workers Brazil Details cholinesterase activity | cytokinetic process | lipid metabolic process | micronucleus organization | nuclear fragmentation involved in apoptotic nuclear change
41. Ueyama J, et al. (2014). In this study, we developed and validated a rapid and sensitive method for quantifying urinary neonicotinoid (NEO) concentrations using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). acetamiprid | clothianidin | dinotefuran | imidacloprid | nitenpyram | thiacloprid | thiamethoxam Study subjects Japan urine acetamiprid | clothianidin | dinotefuran | imidacloprid | nitenpyram | thiacloprid | thiamethoxam Details
42. Marfo JT, et al. (2015). Urinary N-desmethylacetamiprid can be used as a biomarker for environmental exposure to acetamiprid, and detection of N-desmethylacetamiprid was associated with increased prevalence of neurological symptoms. acetamiprid | Insecticides Controls for disease:Neurologic Manifestations | Subjects with disease:Neurologic Manifestations Japan urine clothianidin | N-desmethylacetamiprid | nitenpyram | thiacloprid | thiamethoxam Details Neurologic Manifestations
43. Lai H, et al. (2014). The findings of this study indicate that occupational aflatoxin B1 airway exposure might be associated with the risk of hepatocellular carcinoma among factory workers. Aflatoxin B1 Controls for disease:Carcinoma, Hepatocellular | Subjects with disease:Carcinoma, Hepatocellular | Workers China dust | serum aflatoxin-albumin adduct | Aflatoxin B1 Details Carcinoma, Hepatocellular
44. Groopman JD, et al. (2014). In this study we have found that aflatoxin exposure is ubiquitous among at least some of the rural populations of Nepal and Bangladesh, as assessed by a robust mass spectrometry-based albumin adduct biomarker. Aflatoxin B1 Children | Fetuses | Pregnant females Bangladesh|Nepal blood | blood, cord | serum aflatoxin B1-lysine adduct Details
45. Mizrak D, et al. (2009). We have documented that in viral hepatitis patients, aflatoxin exposure is significantly higher than in healthy subjects in Turkey and it may play an important role in the development of hepatocellular carcinoma. diet | disease Aflatoxins Controls for disease:Hepatitis, Viral, Human | Subjects with disease:Hepatitis, Viral, Human Turkey serum Aflatoxin B1 | aflatoxin B2 | aflatoxin G1 | aflatoxin G2 Details
46. Mitchell NJ, et al. (2017). Malnutrition and Enteric Disease Study (MAL-ED) Exposure to aflatoxin (a mycotoxin common in maize and groundnuts) has been associated with childhood stunting in sub-Saharan Africa; in an effort to further our understanding of growth impairment in relation to mycotoxins, biospecimens from a cohort of children in Bhaktapur (Nepal) were assessed for aflatoxin exposure at 15, 24, and 36 months of age. age Aflatoxins Children Nepal serum aflatoxin B1-lysine adduct Details
47. Yard EE, et al. (2013). Kenya AIDS Indicator Survey (KAIS) Our findings suggest that aflatoxin exposure is a public health problem throughout Kenya, and it could be substantially impacting human health. Aflatoxins Pregnant females | Study subjects Kenya serum aflatoxin B1-lysine adduct Details
48. Liu Y, et al. (2010). Aflatoxin may play a causative role in 4.6-28.2% of all global hepatocellular carcinoma cases. Aflatoxins Study subjects Argentina|Australia|
Brazil|China|
Congo, the Democratic Republic of the|Egypt|
Ethiopia|Gambia|
India|Indonesia|
Iran, Islamic Republic of|Kenya|
Korea, Republic of|Malaysia|
Mexico|Mozambique|
Nigeria|Pakistan|
Philippines|South Africa|
Sudan|Tanzania, United Republic of|
Thailand|United States|
Zimbabwe
Aflatoxins Details Carcinoma, Hepatocellular
49. Jager AV, et al. (2014). We performed a longitudinal assessment to evaluate the short-term exposure to aflatoxins in Sao Paulo (Brazil) by determination of urine levels: aflatoxin M1 was found (but there was no significant difference among the mean levels in four sampling periods), and the levels indicate a low short-term exposure to aflatoxins through the diet. diet Aflatoxins Study subjects Brazil urine Aflatoxin M1 Details
50. Shirima CP, et al. (2015). We investigated the association between child growth and aflatoxin and fumonisin exposure in Tanzania. Aflatoxins | fumonisin B1 Children Tanzania, United Republic of plasma | urine aflatoxin-albumin adduct | fumonisin B1 Details Growth Disorders
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