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Chemical Heterocyclic Compounds, 2-Ring

1–50 of 23,214 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10-(2-(5H-(1,2,4)triazino(5,6-b)indol-3-ylthio)butanoyl)-10H-phenothiazine cell proliferation resveratrol | Sodium Fluoride 10-(2-(5H-(1,2,4)triazino(5,6-b)indol-3-ylthio)butanoyl)-10H-phenothiazine inhibits the reaction [resveratrol inhibits the reaction [Sodium Fluoride results in decreased cell proliferation]] 1: Mus musculus Ameloblasts | Cell Line   1
2. 10-decarbamoylmitomycin C apoptotic process 10-decarbamoylmitomycin C results in increased apoptotic process 1: Homo sapiens Cell Line, Tumor
4 genes: CASP3 | CASP9 | CHEK1 | TP53
1
3. 10-hydroxywarfarin xenobiotic glucuronidation Zidovudine [10-hydroxywarfarin results in decreased xenobiotic glucuronidation] which results in decreased glucuronidation of Zidovudine 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
4. 10-hydroxywarfarin xenobiotic glucuronidation 10-hydroxywarfarin results in decreased xenobiotic glucuronidation 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
5. 10-propargyl-10-deazaaminopterin apoptotic process Cytarabine [Cytarabine co-treated with 10-propargyl-10-deazaaminopterin] results in increased apoptotic process 1: Homo sapiens Tumor Cells, Cultured 1 gene: CASP3 1
6. 10-propargyl-10-deazaaminopterin apoptotic process gemcitabine [10-propargyl-10-deazaaminopterin co-treated with gemcitabine] results in increased apoptotic process 1: Mus musculus Tumor Cells, Cultured 1 gene: CASP3 1
7. 10-propargyl-10-deazaaminopterin cell cycle gemcitabine [10-propargyl-10-deazaaminopterin co-treated with gemcitabine] affects cell cycle 1: Mus musculus Tumor Cells, Cultured   1
8. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons
3 genes: CASP1 | IL1A | TLR4
1
9. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane locomotory behavior 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased locomotory behavior] 1: Mus musculus  
2 genes: SLC6A3 | TH
1
10. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons   1
11. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
12. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
13. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons 1 gene: CASP8 1
14. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons
3 genes: ATF4 | CASP3 | DDIT3
1
15. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell adhesion FN1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [FN1 protein results in increased cell adhesion] 1: Homo sapiens Breast | Cell Line, Tumor
2 genes: ITGB1 | ITGB3
1
16. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation 1: Homo sapiens Kidney | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
17. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane DNA damage response, detection of DNA damage 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: PARP1 1
18. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration TGFB1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [TGFB1 protein results in increased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
19. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration NR4A1 NR4A1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
20. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane calcium ion homeostasis 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane affects calcium ion homeostasis 1: Homo sapiens Pancreas | Cell Line, Tumor   1
21. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Pancreas | Cell Line, Tumor   1
22. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane apoptotic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased apoptotic process 1: Homo sapiens Kidney | Cell Line, Tumor
12 genes: BCL2 | BID | BIRC5 | CASP3 | CASP7 | CASP8 | DDIT3 | EP300 | NR4A1 | PARP1 | RPS6KB1 | XBP1
1
23. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration ITGB1 ITGB1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
24. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation NR4A1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane affects the reaction [NR4A1 protein affects cell proliferation] 1: Homo sapiens Pancreas | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
25. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane apoptotic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased apoptotic process 1: Homo sapiens Pancreas | Cell Line, Tumor
12 genes: BCL2 | BID | BIRC5 | CASP3 | CASP7 | CASP8 | DDIT3 | EP300 | NR4A1 | PARP1 | RPS6KB1 | XBP1
1
26. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process Glutathione Glutathione inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens Pancreas | Cell Line, Tumor   1
27. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation NR4A1 NR4A1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation] 1: Homo sapiens Kidney | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
28. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell adhesion FN1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [FN1 protein results in increased cell adhesion] 1: Homo sapiens MCF-7 Cells
2 genes: ITGB1 | ITGB3
1
29. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Kidney | Cell Line, Tumor   1
30. 1,1-bis(3'-indolyl)-1-(p-anisyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons 1 gene: IL1A 1
31. 1,1-bis(3'-indolyl)-1-(p-anisyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons   1
32. 1,1-bis(3'-indolyl)-1-(p-anisyl)methane locomotory behavior 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased locomotory behavior] 1: Mus musculus  
2 genes: SLC6A3 | TH
1
33. 1,2,3,4,6,7,8-heptachlorodibenzofuran regulation of blood pressure 1,2,3,4,6,7,8-heptachlorodibenzofuran affects regulation of blood pressure 1: Homo sapiens Cardiovascular System 1 gene: AHR 1
34. 1,2,3,4,6,7,8-heptachlorodibenzofuran triglyceride metabolic process 1,2,3,4,6,7,8-heptachlorodibenzofuran affects triglyceride metabolic process 1: Homo sapiens Serum   1
35. 1,2,3,4,7,8-hexachlorodibenzofuran regulation of blood pressure 1,2,3,4,7,8-hexachlorodibenzofuran affects regulation of blood pressure 1: Homo sapiens Cardiovascular System 1 gene: AHR 1
36. 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline cell proliferation 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in decreased cell proliferation 1: Homo sapiens Neurons | Cell Line, Tumor   1
37. 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline cell proliferation 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline metabolite results in decreased cell proliferation 1: Homo sapiens Neurons | Cell Line, Tumor   1
38. 1,2,3,5,6,7-hexahydroquinoxaline glutathione derivative biosynthetic process 2,3,5,6,7,8-hexahydroquinoxaline | Glutathione [[2,3,5,6,7,8-hexahydroquinoxaline co-treated with 1,2,3,5,6,7-hexahydroquinoxaline] results in increased oxidation of Glutathione] which results in increased glutathione derivative biosynthetic process     1
39. 1,2,3,7,8-pentachlorodibenzofuran immunoglobulin secretion involved in immune response 1,2,3,7,8-pentachlorodibenzofuran results in decreased immunoglobulin secretion involved in immune response 1: Mus musculus Serum   1
40. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole cell proliferation gemcitabine [gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor   1
41. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy Acetylcysteine | gemcitabine Acetylcysteine inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
42. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy 3-methyladenine | gemcitabine 3-methyladenine inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
43. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy chloroquine diphosphate | gemcitabine chloroquine diphosphate inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
44. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy gemcitabine [gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
45. 1',2'-dihydrorotenone cell proliferation 1',2'-dihydrorotenone results in decreased cell proliferation 1: Homo sapiens Plasma Cells | Cell Line, Tumor
3 genes: AKT1 | CDK4 | TP53
1
46. 1',2'-dihydrorotenone apoptotic process 1',2'-dihydrorotenone results in increased apoptotic process 1: Homo sapiens Plasma Cells
6 genes: AKT1 | E2F1 | MAPK1 | MAPK3 | RB1 | TP53
1
47. 1',2'-dihydrorotenone mitotic cell cycle arrest 1',2'-dihydrorotenone results in increased mitotic cell cycle arrest 1: Homo sapiens Plasma Cells
2 genes: CDKN1A | TP53
1
48. 1',2'-dihydrorotenone mitotic cell cycle arrest 1',2'-dihydrorotenone results in increased mitotic cell cycle arrest 1: Homo sapiens Plasma Cells | Cell Line, Tumor
2 genes: CDKN1A | TP53
1
49. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction NAADP 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog affects the reaction [NAADP results in increased acrosome reaction] 1: Mus musculus Spermatozoa   1
50. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid microtubule motor activity Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased microtubule motor activity] 1: Mus musculus Coronary Vessels | Muscle Cells   1
1–50 of 23,214 results.