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Chemical Heterocyclic Compounds, 4 or More Rings

These are exposure studies associated with the chemical and all of its children.

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1–11 of 11 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Ayotte P, et al. (2005). In summary, we found no relation between biomarkers of organochlorine exposure and markers of hepatic enzyme induction in this highly exposed group of fish eaters from the Lower North Shore of the St. Lawrence River. Our results suggest that smoking induces liver CYP1A2 activity, which in turn alters porphyrin metabolism and increases the biotransformation of mono-ortho polychlorinated biphenyls. tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Hydrocarbons, Chlorinated | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Study subjects Canada plasma | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Coproporphyrins | Dichlorodiphenyl Dichloroethylene | Glucaric Acid | Hexachlorobenzene | Hydrocarbons, Chlorinated | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls | Uroporphyrins Details enzyme activator activity
2. Kamel F, et al. (2014). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) Polyunsaturated fatty acid intake was consistently associated with lower Parkinson's disease (PD) risk, and dietary fats modified the association of PD risk with pesticide exposure. alpha-Linolenic Acid | Fatty Acids | Fatty Acids, Unsaturated | Paraquat | Rotenone Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
3. Rosado JL, et al. (2007). Children living in an area contaminated with both arsenic and lead showed that arsenic contamination can affect children's cognitive development, independent of any effect of lead. sex | socioeconomic status Arsenic | Copper | Lead | Zinc | zinc protoporphyrin Children Mexico blood | urine Arsenic | Copper | Lead | Zinc | zinc protoporphyrin Details cognition
4. Hall MN, et al. (2009). In summary, among this group of Bangladeshi adults with a high prevalence of cobalamin deficiency, cobalamin appeared to facilitate the methylation of inorganic arsenic to monomethylarsonic acid, particularly among women and among folate sufficient individuals. Arsenic | Creatinine | Folic Acid | Homocysteine | Vitamin B 12 Study subjects Bangladesh plasma | urine | water Arsenic | Creatinine | Folic Acid | Homocysteine | Vitamin B 12 Details
5. George CM, et al. (2013). Health Effects of Arsenic Longitudinal Study (HEALS) Our results suggest that selenium is inversely associated with biomarkers of arsenic burden in both adults and children. Arsenic | Creatinine | Folic Acid | Selenium | Vitamin B 12 Children | Study subjects Bangladesh blood | urine | water Arsenic | Creatinine | Folic Acid | Selenium | Vitamin B 12 Details
6. Hall MN, et al. (2009). Health Effects of Arsenic Longitudinal Study (HEALS) These findings suggest that, similar to adults, folate and cysteine facilitate arsenic methylation in children. However, the inverse correlation between total homocysteine and %monomethylarsonic, and positive correlation with %dimethylarsinic acids, are both opposite to our previous findings in adults. age Arsenic | Cysteine | Folic Acid Children Bangladesh plasma | urine | water Arsenic | Creatinine | Cysteine | Folic Acid | Homocysteine | Vitamin B 12 Details cellular response to chemical stimulus
7. Sunyer J, et al. (2008). The aim of the present study is to assess the association between Hexachlorobenzene and other organochlorines compounds, and urinary porphyrin excretion during childhood, at an age with a more valid assessment of porphyrins than at birth, and without the confounding effect of other determinants occurring at adulthood. Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Hydrocarbons, Chlorinated | Porphyrins Children Spain hair | serum | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | coproporphyrin I | coproporphyrin III | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Methylmercury Compounds | PCB 180 | Porphyrins | uroporphyrin I | uroporphyrin III Details heme biosynthetic process
8. Kasperczyk S, et al. (2014). We examined the effects of N-acetylcysteine administration on the non-enzymatic defense systems (e.g., uric acid, albumin, bilirubin and alpha-tocopherol) in male workers exposed to lead, over a 12 week study period. Lead Workers Poland blood ALB | alpha-Tocopherol | Bilirubin | Lead | Lipid Peroxides | Uric Acid | zinc protoporphyrin Details
9. Rubio-Andrade M, et al. (2011). A follow-up study on lead exposure in children living in a smelter community in northern Mexico indicates that blood lead levels have significantly decreased. This could be explained by environmental interventions by authorities and the smelter companies, normal changes in hygienic habits as children age, and lead redistribution from blood to hard tissues. Lead Children Mexico blood Lead | zinc protoporphyrin Details
10. Furlong M, et al. (2015). Farming and Movement Evaluation Study (FAME) Although sample size was limited, protective glove use and hygiene practices appeared to be important modifiers of the association between pesticides and Parkinson disease and may reduce risk of Parkinson disease associated with certain pesticides. Paraquat | Permethrin | Rotenone | Trifluralin Workers United States Details Parkinson Disease
11. Tanner CM, et al. (2011). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) Parkinson's Disease (PD) was positively associated with two groups of pesticides defined by mechanisms implicated experimentally-those that impair mitochondrial function and those that increase oxidative stress-supporting a role for these mechanisms in PD pathophysiology. Paraquat | Rotenone Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
1–11 of 11 results.