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Chemical Histamine H1 Antagonists

Name Histamine H1 Antagonists
Equivalent Terms Antagonists, Histamine H1 | Antagonists, Histamine H1 Receptor | Antihistamines, Classical | Antihistamines, Sedating | Antihistaminics, Classical | Antihistaminics, H1 | Blockaders, Histamine H1 Receptor | Classical Antihistamines | Classical Antihistaminics | First Generation H1 Antagonists | H1 Antagonists, Histamine | H1 Antihistaminics | H1 Receptor Blockaders | Histamine H1 Blockers | Histamine H1 Receptor Antagonists | Histamine H1 Receptor Blockaders | Receptor Blockaders, H1 | Sedating Antihistamines
Definition Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Curation Status No gene interactions have been curated for this chemical yet.
MeSH® ID D006634
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PubChem
D006634
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1. Chemicals ← Chemical Actions and Uses Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Pharmacologic Actions Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Molecular Mechanisms of Pharmacological Action Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Neurotransmitter Agents Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Histamine Agents Has associated diseases ← Histamine Antagonists Has associated diseases ← Histamine H1 Antagonists Has associated diseases
2. Chemicals ← Chemical Actions and Uses Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Pharmacologic Actions Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Physiological Effects of Drugs Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Neurotransmitter Agents Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references ← Histamine Agents Has associated diseases ← Histamine Antagonists Has associated diseases ← Histamine H1 Antagonists Has associated diseases

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Histamine H1 Antagonists Has associated diseases
  Histamine H1 Antagonists, Non-Sedating Has associated diseases