Name | Histamine H1 Antagonists |
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Equivalent Terms | Antagonists, Histamine H1 | Antagonists, Histamine H1 Receptor | Antihistamines, Classical | Antihistamines, Sedating | Antihistaminics, Classical | Antihistaminics, H1 | Blockaders, Histamine H1 Receptor | Classical Antihistamines | Classical Antihistaminics | First Generation H1 Antagonists | H1 Antagonists, Histamine | H1 Antihistaminics | H1 Receptor Blockaders | Histamine H1 Blockers | Histamine H1 Receptor Antagonists | Histamine H1 Receptor Blockaders | Receptor Blockaders, H1 | Sedating Antihistamines |
Definition | Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. |
Curation Status | No gene interactions have been curated for this chemical yet. |
MeSH® ID | D006634 |
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Chemicals
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Chemical Actions and Uses
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Histamine H1 Antagonists
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Histamine H1 Antagonists, Non-Sedating
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