Histamine H1 Antagonists

Name	Histamine H1 Antagonists
Equivalent Terms	Antagonists, Histamine H1 \| Antagonists, Histamine H1 Receptor \| Antihistamines, Classical \| Antihistamines, Sedating \| Antihistaminics, Classical \| Antihistaminics, H1 \| Blockaders, Histamine H1 Receptor \| Classical Antihistamines \| Classical Antihistaminics \| First Generation H1 Antagonists \| H1 Antagonists, Histamine \| H1 Antihistaminics \| H1 Receptor Blockaders \| Histamine H1 Blockers \| Histamine H1 Receptor Antagonists \| Histamine H1 Receptor Blockaders \| Receptor Blockaders, H1 \| Sedating Antihistamines
Definition	Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Curation Status	No gene interactions have been curated for this chemical yet. Request curation
MeSH^® ID	D006634
External Links	PubChem D006634 TOXLINE^® Query

Top ↑ Ancestors

1.	Chemicals ← Chemical Actions and Uses ← Pharmacologic Actions ← Molecular Mechanisms of Pharmacological Action ← Neurotransmitter Agents ← Histamine Agents ← Histamine Antagonists ← Histamine H1 Antagonists
2.	Chemicals ← Chemical Actions and Uses ← Pharmacologic Actions ← Physiological Effects of Drugs ← Neurotransmitter Agents ← Histamine Agents ← Histamine Antagonists ← Histamine H1 Antagonists

Top ↑ Descendants

Histamine H1 Antagonists
	Histamine H1 Antagonists, Non-Sedating