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Chemical Hydroxy Acids

These are exposure studies associated with the chemical and all of its children.

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1–50 of 98 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Goniewicz ML, et al. (2018). Population Assessment of Tobacco and Health (PATH) Study These findings provide evidence that using combusted tobacco cigarettes alone or in combination with e-cigarettes is associated with higher concentrations of potentially harmful tobacco constituents in comparison with using e-cigarettes alone. tobacco 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-butenal | 2-hydroxyfluorene | 2-naphthol | 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol | Acrolein | Acrylamide | Acrylonitrile | Anabasine | anatabine | Arsenic | Benzene | Beryllium | Cadmium | Carbon Disulfide | Cobalt | Cotinine | cotinine-N-oxide | Dimethylformamide | ethylbenzene | Ethylene Oxide | Fluorenes | hydroxycotinine | Isocyanates | isoprene | Lead | mandelic acid | Manganese | nicotine 1-N-oxide | Nicotine | N'-nitrosoanabasine | N'-nitrosoanatabine | N'-nitrosonornicotine | norcotinine | nornicotine | Phenanthrenes | propylene oxide | Strontium | Styrene | Thallium | Toluene | Uranium | Vinyl Chloride | Xylenes Study subjects United States urine 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-butenal | 2-hydroxyfluorene | 2-methylhippuric acid | 2-naphthol | 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol | Acrolein | Acrylamide | Acrylonitrile | Anabasine | anatabine | Arsenic | Benzene | Beryllium | Cadmium | Carbon Disulfide | Cobalt | Cotinine | cotinine-N-oxide | Dimethylformamide | Fluorenes | Hippurates | hydroxycotinine | isoprene | Lead | mandelic acid | Manganese | N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine | N-acetyl-S-(2-cyanoethyl)cysteine | N-acetyl-S-(2-hydroxyethyl)cysteine | nicotine 1-N-oxide | Nicotine | N'-nitrosoanabasine | N'-nitrosoanatabine | N'-nitrosonornicotine | norcotinine | nornicotine | Phenanthrenes | phenylglyoxylic acid | propylene oxide | S-(3-hydroxypropyl)cysteine N-acetate | S-benzyl-N-acetyl-L-cysteine | Strontium | Thallium | Uranium Details
2. Shahab L, et al. (2017). This study assessed whether long-term e-cigarette (EC)-only, nicotine replacement therapy (NRT)-only, dual cigarette-EC or dual cigarette-NRT use is associated with differences in metabolites of a) nicotine; b) tobacco-specific nitrosaminess and c) volatile organic compounds (VOC) compared with cigarette-only smokers. tobacco 1,3-butadiene | 2-butenal | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Acrolein | Acrylamide | Acrylonitrile | Anabasine | anatabine | Benzene | Carbon Disulfide | Cyanides | Dimethylformamide | ethylbenzene | Ethylene Oxide | Nicotine | N'-nitrosoanabasine | N'-nitrosoanatabine | propylene oxide | Styrene | Vinyl Chloride | Xylenes Study subjects United Kingdom saliva | urine 1,3-butadiene | 2-amino-delta(2)-thiazoline-4-carboxylic acid | 2-butenal | 2-methylhippuric acid | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol | Acrolein | Acrylamide | Acrylonitrile | Anabasine | anatabine | Benzene | Cotinine | cotinine-N-oxide | Dimethylformamide | Hippurates | hydroxycotinine | mandelic acid | muconic acid | N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine | nicotine 1-N-oxide | Nicotine | N'-nitrosoanabasine | N'-nitrosoanatabine | norcotinine | nornicotine | phenylglyoxylic acid | propylene oxide | raphanusamic acid | S-(3-hydroxypropyl)cysteine N-acetate | Styrene Details
3. Hofmann JN, et al. (2013). Shanghai Women's Health Study (SWHS) In this nested case-control study among participants in the Shanghai Women's Health Study, we did not find evidence of an association between urinary concentration of 1-hydroxypyrene glucuronide, an established marker of polycyclic aromatic hydrocarbon exposure, and risk of colorectal cancer. 1-hydroxypyrene-glucuronide | Polycyclic Aromatic Hydrocarbons Controls for disease:Colorectal Neoplasms | Subjects with disease:Colorectal Neoplasms | Study subjects China urine 1-hydroxypyrene-glucuronide Details Colorectal Neoplasms
4. Ayotte P, et al. (2005). In summary, we found no relation between biomarkers of organochlorine exposure and markers of hepatic enzyme induction in this highly exposed group of fish eaters from the Lower North Shore of the St. Lawrence River. Our results suggest that smoking induces liver CYP1A2 activity, which in turn alters porphyrin metabolism and increases the biotransformation of mono-ortho polychlorinated biphenyls. tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Hydrocarbons, Chlorinated | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Study subjects Canada plasma | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Coproporphyrins | Dichlorodiphenyl Dichloroethylene | Glucaric Acid | Hexachlorobenzene | Hydrocarbons, Chlorinated | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls | Uroporphyrins Details enzyme activator activity
5. Patel CJ, et al. (2012). National Health and Nutrition Examination Survey (NHANES) We screened for correlation between environmental factors and lipid levels, utilizing four independent surveys with information on 188 environmental factors from the Centers of Disease Control, National Health and Nutrition Examination Survey, collected between 1999 and 2006. age | body mass index | race | sex | socioeconomic status 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2,4,4',5-tetrachlorobiphenyl | 2-hydroxyfluorene | alpha-Tocopherol | Ascorbic Acid | beta Carotene | Cotinine | Cryptoxanthins | Fluorenes | Folic Acid | gamma-Tocopherol | Heptachlor Epoxide | Iron | Lycopene | Mercury | nonachlor | oxychlordane | retinol palmitate | retinyl stearate | Vitamin A | Vitamin D Study subjects United States Details cholesterol metabolic process | triglyceride metabolic process
6. Béranger R, et al. (2016). PELAGIE Prenatal urine concentrations of two glycol ethers metabolites were associated with lower Wechsler Intelligence Scale for Children IV Verbal Comprehension Index scores and Developmental Neuropsychological Assessment Design Copying subscale scores, respectively, at age six. 2-(2-methoxyethoxy)ethanol | carbitol | Ethylene Glycols | n-butoxyacetic acid | phenoxyethanol Children | Pregnant females France urine carbitol | ethoxyacetic acid | methoxyacetic acid | n-butoxyacetic acid | phenoxyacetic acid Details cognition | visual learning
7. Arcury TA, et al. (2007). In this investigation we documented the pesticide urinary metabolite levels of farmworker children in North Carolina, determined the number of different metabolites detected for each child, and delineated risk factors associated with the number of metabolites. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | 3-phenoxybenzoic acid | acetochlor | Atrazine | Chlorpyrifos | Coumaphos | DEET | Diazinon | isazophos | Malathion | metolachlor | Parathion | pirimiphos methyl Children United States urine 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | 3-phenoxybenzoic acid | acetochlor | Atrazine | Chlorpyrifos | Coumaphos | DEET | Diazinon | isazophos | Malathion | metolachlor | Parathion | pirimiphos methyl Details
8. Bakke B, et al. (2009). Agricultural Health Study (AHS) We measured the exposure to atrazine and selected non-persistent pesticides among corn farmers during a growing season; urinary atrazine mercapturate levels in farmers were largely driven by recent application of atrazine; therefore, the amount of atrazine applied is likely to provide valid surrogates of atrazine exposure in epidemiologic studies. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | acetochlor | Atrazine | Chlorpyrifos | Coumaphos | Diazinon | Malathion | Methyl Parathion | metolachlor | pirimiphos methyl | Pyrethrins Workers United States urine 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol | 3-phenoxybenzoic acid | acetochlor mercapturate | atrazine mercapturate | chlorferron | Diazinon | Malathion | Methyl Parathion | metolachlor | pirimiphos methyl Details
9. Goldner WS, et al. (2010). Agricultural Health Study (AHS) These data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldrin | Atrazine | Benomyl | butylate | Captan | Carbaryl | Carbon Disulfide | Carbon Tetrachloride | Chlordan | chlorimuron ethyl | Chlorpyrifos | cyanazine | DDT | Diazinon | Dicamba | Dichlorvos | EPTC | Fonofos | Fungicides, Industrial | glyphosate | Heptachlor | Hexachlorocyclohexane | Hydrocarbons, Chlorinated | imazethapyr | Insecticides | Malathion | mancozeb | Maneb | metalaxyl | methyl bromide | metolachlor | metribuzin | Paraquat | Parathion | pendimethalin | Petroleum | terbufos | tetrachloroisophthalonitrile | Trifluralin Study subjects United States Details Agricultural Workers' Diseases | Hyperthyroidism | Hypothyroidism
10. Goldner WS, et al. (2013). Agricultural Health Study (AHS) We found statistically significant associations between specific herbicides and insecticides and hypothyroid disease in male pesticide applicators. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldrin | butylate | Carbofuran | Chlordan | DDT | Diazinon | Dicamba | fenoprop | Heptachlor | Hexachlorocyclohexane | Malathion | metalaxyl | Parathion | Petroleum | Toxaphene Workers United States Details Agricultural Workers' Diseases | Hyperthyroidism | Hypothyroidism
11. Waggoner JK, et al. (2013). Agricultural Health Study (AHS) In this large cohort of male farmers, pesticide use, in addition to farm machinery use, was associated with fatal injury. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | metribuzin | Paraquat | Ziram Workers United States Details Death
12. Beard JD, et al. (2014). Agricultural Health Study (AHS) Our study supports a positive association between pesticide exposure and depression, including associations with several specific pesticides. 2,4,5-Trichlorophenoxyacetic Acid | aluminum phosphide | Diazinon | Dieldrin | Ethylene Dibromide | Hydrocarbons, Chlorinated | Malathion | Parathion | Pesticides Workers United States Details Agricultural Workers' Diseases | Depressive Disorder
13. Saldana TM, et al. (2007). Agricultural Health Study (AHS) These findings suggest that activities involving exposure to agricultural pesticides during the first trimester of pregnancy may increase the risk of gestational diabetes mellitus. 2,4,5-Trichlorophenoxyacetic Acid | Atrazine | butylate | Carbofuran | Diazinon | fenoprop | Pesticides | Phorate Mothers United States Details Agricultural Workers' Diseases | Diabetes, Gestational
14. Kamel F, et al. (2007). Agricultural Health Study (AHS) This study suggests that exposure to certain pesticides may increase Parkinson's disease risk. 2,4,5-Trichlorophenoxyacetic Acid | Benomyl | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | Dicamba | Ethylene Dibromide | Hexachlorocyclohexane | mancozeb | Maneb | methyl bromide | Paraquat | pendimethalin | Pesticides | Phorate | tetrachloroisophthalonitrile Study subjects | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
15. Engel LS, et al. (2005). Agricultural Health Study (AHS) While pesticide use overall is not associated with an increased rate of breast cancer among the wives of farmers in the Agricultural Health Study cohort, use of certain pesticides may be related to increased risk. These include the herbicides 2,4,5-trichloro-phenoxypropionic acid and 2,4,5-trichlorophenoxyacetic acid, the insecticide dieldrin, and the fungicide captan. 2,4,5-Trichlorophenoxyacetic Acid | Captan | Dieldrin | fenoprop Study subjects United States Details Breast Neoplasms
16. Hoppin JA, et al. (2007). Agricultural Health Study (AHS) These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence. 2,4,5-Trichlorophenoxyacetic Acid | Carbaryl | Carbofuran | chlorimuron ethyl | DDT | Diazinon | Dichlorvos | fenoprop | Heptachlor | Malathion | Permethrin Workers United States Details Agricultural Workers' Diseases | Bronchitis, Chronic
17. Koutros S, et al. (2011). Agricultural Health Study (AHS) We evaluated pesticide-single nucleotide polymorphism (SNP) interactions between 45 pesticides and 1913 xenobiotic metabolic enzyme SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study. genetics 2,4,5-Trichlorophenoxyacetic Acid | Carbaryl | Diazinon | Dieldrin | Fonofos | Hexachlorocyclohexane | methyl bromide | Petroleum | Phorate | terbufos Subjects with gene influence:GCLC | Workers United States Details Agricultural Workers' Diseases | Prostatic Neoplasms
18. Godduhn A, et al. (2013). Northway Health Study (NHS) The NHS found complex patterns of association between reported resource uses and cancer and thyroid-, reproductive-, metabolic-, and cardiac problems. 2,4,5-Trichlorophenoxyacetic Acid | Chlorine | Pesticides | Petroleum | Vehicle Emissions Study subjects United States Details Cardiovascular Diseases | Neoplasms | Thyroid Diseases | Urologic Diseases
19. Starling AP, et al. (2014). Agricultural Health Study (AHS) Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study 2,4,5-Trichlorophenoxyacetic Acid | Dieldrin | fenoprop | Fonofos | Parathion | Phorate Study subjects United States Details Agricultural Workers' Diseases | Diabetes Mellitus
20. Vernet C, et al. (2018). SEPAGES During pregnancy, phenol biomarkers showed a strong within-day variability, while the variability between days of a given week was more limited. 2,4-dichlorophenol | 2,5-dichlorophenol | bis(4-hydroxyphenyl)sulfone | bisphenol A | butylparaben | ethyl-p-hydroxybenzoate | methylparaben | oxybenzone | propylparaben | Triclosan Pregnant females France urine 2,4-dichlorophenol | 2,5-dichlorophenol | bis(4-hydroxyphenyl)sulfone | bisphenol A | butylparaben | ethyl-p-hydroxybenzoate | methylparaben | oxybenzone | propylparaben | Triclosan Details
21. LaRocca J, et al. (2015). Harvard Epigenetic Birth Cohort (HEBC) These results suggest that prenatal phenol and phthalate exposure is associated with altered microRNA expression in placenta, suggesting a potential mechanism of endocrine-disrupting chemicals toxicity in humans. 2,4-dichlorophenol | 2,5-dichlorophenol | bisphenol A | butylbenzyl phthalate | butylparaben | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisodecyl phthalate | diisononyl phthalate | methylparaben | oxybenzone | Parabens | Phenols | Phthalic Acids | propylparaben | Triclosan Infants or newborns | Pregnant females United States placenta | urine 2,4-dichlorophenol | 2,5-dichlorophenol | 2-ethyl-5-carboxypentyl phthalate | bisphenol A | butylparaben | diisodecyl phthalate | diisononyl phthalate | methylparaben | MIR142 | MIR15A | MIR185 | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | oxybenzone | propylparaben | Triclosan Details regulation of gene silencing by miRNA
22. Schreinemachers DM. (2010). National Health and Nutrition Examination Survey (NHANES) The results indicate that exposure to 2,4-dichlorophenoxyacetic acid was associated with changes in biomarkers that, based on the published literature, have been linked to risk factors for acute myocardial infarction and type 2 diabetes. 2,4-Dichlorophenoxyacetic Acid Study subjects United States urine 2,4-Dichlorophenoxyacetic Acid Details Diabetes Mellitus, Type 2 | Heart Diseases | cellular triglyceride homeostasis | glucose metabolic process | insulin metabolic process | thyroid-stimulating hormone secretion
23. Carreón T, et al. (2005). Upper Midwest Health Study (UMHS) Results show that exposure to pesticides was not associated with an increased risk of intracranial gliomas in women. 2,4-Dichlorophenoxyacetic Acid | 2-chloro-N-(ethoxymethyl)-N-(2-methyl-6-(trifluoromethyl)phenyl)acetamide | alachlor | Aniline Compounds | Arsenicals | Atrazine | bentazone | Benzoic Acid | Carbamates | cyanazine | DDT | Diazinon | Dicamba | Hydrocarbons, Chlorinated | imazethapyr | Inorganic Chemicals | Malathion | metolachlor | Organophosphates | pendimethalin | Pesticides | Triazines | Trifluralin Controls for disease:Glioma | Subjects with disease:Glioma United States Details Glioma
24. Jurewicz J, et al. (2012). The presented study confirms that farmers' spouses are exposed to pesticides after spraying, which indicates that there is transfer of pesticides from the field to the home environment. 2,4-Dichlorophenoxyacetic Acid | 2-Methyl-4-chlorophenoxyacetic Acid Study subjects Poland urine 2,4-Dichlorophenoxyacetic Acid | 2-Methyl-4-chlorophenoxyacetic Acid | Herbicides Details
25. Munger R, et al. (1997). We conclude that communities in southern Iowa with drinking water supplies contaminated with herbicides have elevated rates of intrauterine growth retardation compared to neighboring communities with different water supplies. 2,4-Dichlorophenoxyacetic Acid | 2-xylene | 3-xylene | 4-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane Pregnant females United States water, drinking 2,4-Dichlorophenoxyacetic Acid | 2-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane | Xylenes Details Fetal Growth Retardation
26. Swan SH, et al. (2003). Study for Future Families (SFF) This is the first population-based study to demonstrate links between specific biomarkers of environmental exposures and biomarkers of male reproduction in humans. 2,4-Dichlorophenoxyacetic Acid | acetochlor | alachlor | Atrazine | DEET | Diazinon | Malathion | metolachlor Controls for disease:Infertility, Male | Subjects with disease:Infertility, Male | Study subjects United States semen 2,4-Dichlorophenoxyacetic Acid | acetochlor | alachlor | Atrazine | DEET | Diazinon | Malathion | metolachlor Details Infertility, Male
27. Hoppin JA, et al. (2017). Agricultural Health Study (AHS) We evaluated the association of currently used pesticides with allergic and non-allergic wheeze among male farmers, and our results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects. 2,4-Dichlorophenoxyacetic Acid | acetochlor | Atrazine | bentazone | Carbaryl | Chlorpyrifos | clomazone | clopyralid | cyfluthrin | Dicamba | Dimethoate | Disulfoton | fenoxaprop ethyl | fluazifop-butyl | glyphosate | Herbicides | imazaquin | Insecticides | Malathion | mesotrione | metolachlor | N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide | nicosulfuron | Permethrin | Petroleum | Picloram | Pyrethrins | Rodenticides | Simazine | triclopyr | Trifluralin | Warfarin Workers United States Details Respiratory Sounds | Rhinitis, Allergic
28. Hoppin JA, et al. (2002). Agricultural Health Study (AHS) Prevalence of wheeze was associated with individual pesticides independent of animals, crops, and grains. disease 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldicarb | aluminum phosphide | Atrazine | Benomyl | butylate | Captan | Carbaryl | Carbofuran | chlorimuron ethyl | Chlorpyrifos | Coumaphos | cyanazine | Diazinon | Dicamba | Dichlorvos | EPTC | Fonofos | glyphosate | Hexachlorocyclohexane | imazethapyr | Malathion | Maneb | metalaxyl | metolachlor | metribuzin | Paraquat | Parathion | pendimethalin | Permethrin | Petroleum | Phorate | terbufos | tetrachloroisophthalonitrile | Trichlorfon | Trifluralin | Ziram Subjects with disease:Asthma | Subjects with disease:Ige Responsiveness, Atopic | Workers United States Details Agricultural Workers' Diseases | Respiratory Sounds
29. Andreotti G, et al. (2014). Agricultural Health Study (AHS) We found two herbicides (alachlor and 2,4-dichlorophenoxyacetic acid) and two insecticides (diazinon and aldrin) significantly associated with alterations in relative telomere length in blood DNA. 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldrin | Diazinon Workers United States Details telomere maintenance
30. Hou L, et al. (2013). Agricultural Health Study (AHS) Seven pesticides previously associated with cancer risk in the epidemiologic literature were inversely associated with relative telomere length in buccal cell DNA among cancer-free pesticide applicators. age 2,4-Dichlorophenoxyacetic Acid | alachlor | DDT | metolachlor | Permethrin | Toxaphene | Trifluralin Workers United States Details telomere maintenance
31. Lee WJ, et al. (2007). Agricultural Health Study (AHS) This explorative study suggests an association between the incidence of colorectal cancer and use of certain pesticides, in particularly chlorpyrifos and aldicarb, although some findings could be due to chance. age | body mass index | tobacco 2,4-Dichlorophenoxyacetic Acid | Aldicarb | Carbaryl | Chlorpyrifos | Fonofos | Toxaphene Workers United States Details Agricultural Workers' Diseases | Colorectal Neoplasms | Rectal Neoplasms
32. Slager RE, et al. (2009). Agricultural Health Study (AHS) Exposure to pesticides may increase the risk of rhinitis. 2,4-Dichlorophenoxyacetic Acid | Benomyl | Carbofuran | Diazinon | glyphosate | Petroleum Workers United States Details Agricultural Workers' Diseases | Rhinitis
33. Hoppin JA, et al. (2008). Agricultural Health Study (AHS) These findings suggest that pesticides may contribute to atopic asthma, but not nonatopic asthma, among farm women. 2,4-Dichlorophenoxyacetic Acid | Carbamates | Carbaryl | Coumaphos | DDT | glyphosate | Hydrocarbons, Chlorinated | Malathion | metalaxyl | Organophosphates | Parathion | Permethrin | Pesticides | Phorate Study subjects United States Details Agricultural Workers' Diseases | Asthma
34. Coble J, et al. (2011). Agricultural Health Study (AHS) Revised weighting factors in a pesticide exposure intensity algorithm were developed for use in epidemiologic analyses for the Agricultural Health Study by using exposure monitoring data from two monitoring substudies in combination with the world's exposure literature and Pesticide Handlers Exposure Database. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos Workers United States urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol Details
35. Thomas KW, et al. (2010). Agricultural Health Study (AHS) This study provides a direct assessment of the intensity score algorithm within the Agricultural Health Study cohort for several application methods. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos Workers United States urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol Details
36. Thomas KW, et al. (2010). Agricultural Health Study (AHS) This study provides information on pesticide exposures and possible exposure determinants for several application methods commonly used by farmers and will provide information to assess and refine exposure classification; results may also be of use in pesticide safety education for reducing exposures to pesticide applicators. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos Workers United States air, personal | body region | hand | urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol | Chlorpyrifos Details
37. Mandel JS, et al. (2005). The results of the study showed that exposure to farm family members can be quantified using biological markers of exposure and the exposure was variable by chemical largely, though not exclusively, determined by the degree of direct contact with the application process. 2,4-Dichlorophenoxyacetic Acid | Chlorpyrifos | Herbicides Children | Study subjects | Workers United States urine 2,4-Dichlorophenoxyacetic Acid | 3,5,6-trichloro-2-pyridinol | Herbicides Details
38. Aszyk J, et al. (2017). Liquid chromatography-tandem mass spectrometry with electrospray ionization methods were developed for the simultaneous determination of 42 flavouring compounds and nicotine in liquids for e-cigarettes. 2,5-dimethylpyrazine | 2,6-lutidine | 2-acetylpyrrole | 5-methyl-2-furfural | benzyl acetate | cyclotene | diethyl succinate | ethyl acetoacetate | ethyl lactate | ethyl maltol | ethyl vanillin | furaneol | gamma-valerolactone | linalool | maltol | Menthol | menthone | methyl cinnamate | methylheptenone | methyl salicylate | Nicotine | pyridine | tetramethylpyrazine | vanillin Poland e-cigarette 2,5-dimethylpyrazine | 2,6-lutidine | 2-acetylpyrrole | 5-methyl-2-furfural | benzyl acetate | cyclotene | diethyl succinate | ethyl acetoacetate | ethyl lactate | ethyl maltol | ethyl vanillin | furaneol | gamma-valerolactone | linalool | maltol | Menthol | menthone | methyl cinnamate | methylheptenone | methyl salicylate | Nicotine | pyridine | tetramethylpyrazine | vanillin Details
39. Nazaroff W, et al. (2012). The study introduces the intake-to-production ratio as an economy-wide quantitative indicator of the extent to which chemical production results in human exposure. This ratio is well suited as an aggregate metric of exposure intensity for characterizing population-level exposure to synthesized chemicals, particularly those that move fairly rapidly from manufacture to human intake and have relatively stable production and intake rates. 4-dichlorobenzene | bisphenol A | butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | methylparaben | Triclosan Study subjects United States 4-dichlorobenzene | bisphenol A | butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | methylparaben | Triclosan Details
40. Smarr MM, et al. (2017). Longitudinal Investigation of Fertility and the Environment Study (LIFE) Higher quartiles of preconception urinary concentrations of methyl paraben and ethyl paraben among female partners were associated with reduced couple fecundity in partner-specific and couple-based exposure models. sex 4-hydroxybenzoic acid | Anti-Infective Agents | benzylparaben | butylparaben | ethyl-p-hydroxybenzoate | heptylparaben | methylparaben | Parabens | propylparaben | protocatechuic acid | triclocarban | Triclosan Study subjects United States urine 4-hydroxybenzoic acid | benzylparaben | butylparaben | Creatinine | ethyl-p-hydroxybenzoate | heptylparaben | methylparaben | propylparaben | protocatechuic acid | triclocarban | Triclosan Details Infertility, Female | reproductive process
41. Dodson RE, et al. (2012). Common products contain complex mixtures of Endocrine-disrupting compounds and asthma-related compounds. 4-nonylphenol | 4-tert-octylphenol | benzophenone | benzyl acetate | bisphenol A | butylbenzyl phthalate | butylparaben | decamethylcyclopentasiloxane | Dibutyl Phthalate | dicyclohexyl phthalate | diethanolamine | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisononyl phthalate | di-n-hexyl phthalate | di-n-octyl phthalate | di-n-propylphthalate | Ethanolamine | ethyl-p-hydroxybenzoate | Eugenol | galaxolide | Limonene | linalool | methyleugenol | methylionone | methylparaben | methyl salicylate | musk ketone | musk xylene | n-butoxyethanol | octamethylcyclotetrasiloxane | octylmethoxycinnamate | oxybenzone | phenoxyethanol | Phenyl Ethers | Phenylethyl Alcohol | pichtosin | triclocarban | Triclosan United States air freshener | air freshener, car | baking soda | bar soap | body lotion | body wash | Borax | car interior cleaner | carpet cleaner | cat litter | conditioner | deodorant | diaper | dish liquid | dishwasher detergent | dryer sheet | fabric refresher | facial cleanser | facial lotion | floor cleaner | foundation | fragrance or perfume | glass cleaner | hair gel | hair spray or mousse or gel | hand sanitizer | hand soap | laundry bleach | laundry detergent | lip balm | lipstick | mascara | nail polish | pillow protector | polish or wax | scrubbing powder | shampoo | shaving cream | shower curtain, vinyl | stain remover | sunscreen | sunscreen composite | surface cleaner | toilet bowl cleaner | toothpaste | tub and tile cleaner | wet mop 4-nonylphenol | 4-tert-octylphenol | benzophenone | benzyl acetate | bisphenol A | butylbenzyl phthalate | butylparaben | decamethylcyclopentasiloxane | Dibutyl Phthalate | dicyclohexyl phthalate | diethanolamine | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisononyl phthalate | di-n-hexyl phthalate | di-n-octyl phthalate | di-n-propylphthalate | Ethanolamine | ethyl-p-hydroxybenzoate | Eugenol | galaxolide | Limonene | linalool | methyleugenol | methylionone | methylparaben | methyl salicylate | musk ketone | musk xylene | n-butoxyethanol | octamethylcyclotetrasiloxane | octylmethoxycinnamate | oxybenzone | phenoxyethanol | Phenyl Ethers | Phenylethyl Alcohol | pichtosin | triclocarban | Triclosan Details
42. Kim JS, et al. (2003). We conclude that exposure to Agent Orange is associated with various health impacts in Korean Vietnam veterans. Agent Orange Veterans Vietnam Details Diabetes Mellitus | Eczema | Heart Valve Diseases | Hypertension | Myocardial Ischemia | Peripheral Nervous System Diseases | Radiculopathy | Retinal Diseases
43. Fujiyoshi PT, et al. (2006). Air Force Health Study These results show that the mRNA ratio of SLC2A4 to NFKB1 is a reliable marker for the diabetogenic action of dioxin, particularly at very low exposure levels that are not much higher than those found in the general public. Agent Orange Veterans United States adipose tissue | serum Dioxins | NFKB1 | SLC2A4 Details Diabetes Mellitus, Type 2
44. Zafar MB, et al. (2001). Agent Orange may have a role in the causation of some types of cancer but we identified no significant relationship of prostate cancer with Agent Orange exposure in patients referred for prostate biopsy. Agent Orange | Defoliants, Chemical Veterans United States Details Prostatic Neoplasms
45. Kern PA, et al. (2004). These data suggest that high blood tetrachlorodibenzodioxin (TCDD) levels, from exposure to Agent Orange, may promote an insulin-resistant state, but the magnitude of this effect appeared to be small, such that an 18-fold increase in blood TCDD resulted in only a 10% change in insulin sensitivity. Agent Orange | Defoliants, Chemical Veterans United States serum Tetrachlorodibenzodioxin Details Insulin Resistance
46. Michalek JE, et al. (2001). We found an increased risk of 'other liver disorders' among veterans with the highest dioxin levels; whether the associations observed were causal is unclear from these data. Agent Orange | Defoliants, Chemical Veterans United States serum Tetrachlorodibenzodioxin Details Liver Diseases
47. Chamie K, et al. (2008). Individuals who were exposed to Agent Orange had an increased incidence of prostate cancer, developed the disease at a younger age, and had a more aggressive variant than their unexposed counterparts. Agent Orange | Defoliants, Chemical Veterans United States Details Prostatic Neoplasms
48. Beard JD, et al. (2016). Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis (GENEVA) We evaluated associations between military-related factors and amyotrophic lateral sclerosis using data from a case-control study of US military veterans; among some of the positive associations (needing confirmation) were exposure to military herbicides, military nasopharyngeal radium, and Agent Orange. Agent Orange | Defoliants, Chemical | Radium Subjects with disease:Amyotrophic Lateral Sclerosis | Veterans United States Details Amyotrophic Lateral Sclerosis
49. Lundström SL, et al. (2011). Several of the altered oxylipins have known or suspected bronchoprotective or anti-inflammatory effects, suggesting a possible reduced anti-inflammatory response in asthmatics following exposure to subway air. disease Air Pollutants Controls for disease:Asthma | Subjects with disease:Asthma Sweden lung 12,13-epoxy-9- keto-10-octadecenoic acid | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid | 13-hydroxy-9,11-octadecadienoic acid | 13-Hydroxy-octadecatrienoic acid | 13-oxo-9,11-octadecadienoic acid | 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid | 15-hydroxy-5,8,11,13-eicosatetraenoic acid | 15-hydroxyeicosatrienoic acid | 15-keto-5,8,11,13-eicosatetraenoic acid | 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid | 5,6-epoxy-8,11,14-eicosatrienoic acid | 5-hydroxy-6,8,11,14-eicosatetraenoic acid | 8,9-epoxyeicosatrienoic acid | 9,10,13-trihydroxyoctadec-11-enoic acid | 9,12,13-trihydroxy-10-octadecenoic acid | 9-hydroxy-10,12-octadecadienoic acid | 9-oxo-10,12-octadecadienoic acid | ALOX15 | Dinoprostone | Leukotriene B4 | PPARG | Prostaglandin D2 | PTGS1 | PTGS2 | Thromboxane B2 Details negative regulation of inflammatory response | oxylipin biosynthetic process
50. Christensen CH, et al. (2016). Agricultural Health Study (AHS) In this case-control study nested within the Agricultural Health Study cohort, we evaluated evidence of statistical interaction between pesticide exposure and single nucleotide polymorphisms in genes involved in steroid hormone signaling, metabolism, or regulation with the risk of prostate cancer. genetics alachlor | butylate | Carbaryl | Dicamba | Fonofos | Malathion | terbufos Subjects with gene influence:ESR1 | Subjects with gene influence:HSD17B4 | Subjects with gene influence:SHBG | Subjects with gene influence:SRD5A1 | Subjects with gene influence:SULT2A1 | Workers United States Details Prostatic Neoplasms
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