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Chemical Hydroxycholecalciferols

These diseases are associated with Hydroxycholecalciferols or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 3,660 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. seocalcitol Hypercalcemia M
4 genes: CYP24A1 | CYP27B1 | PTH | PTHLH
15.15 13
2. calcipotriene Dermatitis, Atopic M
3 genes: FLG | MAPK8 | TSLP
13.01 8
3. 1,25-dihydroxy-16-ene-vitamin D3 Hypercalcemia M
2 genes: CYP24A1 | PTH
10.60 10
4. Calcitriol Calcinosis M
11 genes: BGLAP | CASP3 | CCL2 | COL1A1 | FGF23 | IL1B | LCN2 | LSP1 | MMP2 | MMP9 | SPP1
10.20 6
5. Calcitriol Infertility, Female M
12 genes: AR | CEBPA | CEBPB | CYP19A1 | ESR1 | LEP | MAPK1 | MAPK3 | MTHFR | NR1I2 | PAPPA | TP53
9.98 8
6. Calcitriol Poisoning M
3 genes: ABCB1 | BCHE | CDKN2B
9.59 7
7. alfacalcidol Hypercalcemia M
3 genes: CYP24A1 | PTH | TNF
9.57 11
8. seocalcitol Hypercalciuria M
2 genes: CYP24A1 | PTH
9.32 4
9. maxacalcitol Hypercalcemia M
2 genes: CYP24A1 | PTH
8.81 11
10. Calcifediol Hypercalcemia M
2 genes: CYP24A1 | CYP27B1
8.44 3
11. Calcitriol Hypertension M
58 genes: ABCC1 | ADIPOQ | AGTR1B | AOC3 | AR | ATP1A1 | ATP1A2 | ATP2B1 | BCL2 | CAV1 | CCL2 | COL1A1 | COL3A1 | CRP | CXCL2 | CYP1A1 | DUSP5 | EDN1 | ELN | FOS | GAL | GCLC | GJA4 | GUCY1A3 | HMOX1 | HSD11B1 | HSD11B2 | IER3 | IGF1 | INS | KCNJ1 | LEP | LPL | LTF | MCPT1 | MMP2 | NOS2 | NOS3 | OLR1 | PPARA | PPARG | PTGS2 | PTH | RELA | REN | SCNN1A | SCNN1B | SOD2 | SOD3 | STK39 | TGFB1 | TGM2 | TNF | TP53 | UCP2 | VAV3 | VDR | VWF
6.46 100
12. Calcitriol Bone Diseases, Metabolic M
6 genes: CYP27A1 | DHCR7 | ESR1 | GC | IGF1 | MMP2
5.89 5
13. maxacalcitol Hyperphosphatemia M   1 gene: PTH 5.58 2
14. 1 alpha,24-dihydroxyvitamin D3 Hypercalciuria M   1 gene: CYP24A1 5.41 3
15. Ro 23-7553 Hypercalcemia M   1 gene: PTH 5.10 8
16. alfacalcidol Hyperphosphatemia M   1 gene: PTH 4.92 2
17. alfacalcidol Acute Kidney Injury M
3 genes: ALB | TGFB1 | TNF
4.84 8
18. 24,25-Dihydroxyvitamin D 3 Hypocalcemia M   1 gene: PTH 4.82 3
19. 1 alpha,24-dihydroxyvitamin D3 Hypercalcemia M   1 gene: CYP24A1 4.81 4
20. Calcitriol Drug Eruptions M
4 genes: ALOX5 | CYP1A1 | IL4 | MTHFR
4.60 4
21. calcipotriene Hypercalcemia M   1 gene: CYP24A1 4.50 6
22. Calcitriol Hypertrophy, Left Ventricular M
9 genes: ACTA1 | COL1A1 | COL3A1 | EDN1 | GDF15 | HBEGF | MYC | PPP3CA | REN
3.96 10
23. Calcitriol Hyperphosphatemia M
2 genes: FGF23 | PTH
3.89 9
24. Calcitriol AORTIC VALVE DISEASE 1 M   1 gene: MGP 3.79 2
25. Calcitriol Nephrocalcinosis M   1 gene: PHEX 3.48 6
26. Calcitriol Uterine Diseases M   1 gene: CGA 3.35 2
27. Calcitriol Hypercalciuria M
2 genes: CYP24A1 | PTH
3.22 12
28. Calcitriol Nephrolithiasis M   1 gene: CYP24A1 3.20 2
29. Calcitriol Myoglobinuria M   1 gene: LDHA 3.11 2
30. Calcitriol Weight Loss M
9 genes: ADIPOQ | ATG5 | IFNA2 | IL10 | IL4 | INS | LTF | MAPT | TSC22D3
3.01 9
31. Calcitriol Ovarian Diseases M
2 genes: CGA | CYP19A1
2.99 3
32. Calcitriol Kidney Calculi M   1 gene: SPP1 2.96 3
33. Calcitriol Aneurysm M   1 gene: MMP1 2.93 2
34. Calcitriol Aortic Diseases M
3 genes: MMP2 | MMP9 | SOD2
2.85 3
35. Calcitriol Gout M
2 genes: CD14 | IL1B
2.70 2
36. Calcitriol Lymphoma, Non-Hodgkin M
6 genes: BCL2 | CHEK2 | IFNA2 | MTHFR | RAD54L | TYMS
1.91 8
37. alfacalcidol Alkalosis M     1
38. Calcitriol Alkalosis M     1
39. Calcitriol Angioedema M     1
40. 24,25-Dihydroxyvitamin D 3 Bone Diseases, Metabolic M     1
41. Dihydroxycholecalciferols Drug-Related Side Effects and Adverse Reactions M     1
42. 1,25-(dihydroxy-21-(3-hydorxy-3-methyl-butyl)-nor-cholecalciferol) Hypercalcemia M     1
43. Dihydroxycholecalciferols Hypercalcemia M     1
44. calcipotriene Hypernatremia M     1
45. maxacalcitol Kidney Failure, Chronic M     1
46. Calcitriol Mood Disorders M     1
47. alfacalcidol Nephrocalcinosis M     1
48. Ro 23-7553 Nephrocalcinosis M     1
49. Hydroxycholecalciferols Nephrolithiasis M     1
50. Calcitriol Parathyroid Diseases M     1
1–50 of 3,660 results.