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Chemical Indazoles

1–50 of 57 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine cell death palbociclib [palbociclib results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased cell death 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
2 genes: CDKN1B | OPTN
1
2. 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine cell proliferation 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in decreased cell proliferation 1: Homo sapiens Blood | Cell Line, Tumor
46 genes: AKT1 | AR | AREG | BAD | BAX | BCL2 | BOK | BOP1 | CDC25A | CDK1 | CDK5R1 | CITED2 | DKC1 | EGFR | EHF | EIF4B | ELF5 | ERBB2 | FOXN1 | GSK3B | HHEX | IGF1 | IL18 | INSIG1 | IRS2 | MAP2K1 | MCM10 | MET | MYC | NRG1 | PA2G4 | PDK1 | PDXK | PIM1 | POLR3G | PRKDC | PTEN | SKP2 | STAT3 | TCF19 | TNF | TP53 | UBR5 | UHRF1 | VEGFA | YPEL5
1
3. 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine positive regulation of cell death 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased positive regulation of cell death 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor
5 genes: ACOX2 | BCL2L11 | CDKN1A | CDKN1B | MTOR
1
4. 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine positive regulation of cell death 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased positive regulation of cell death 1: Mus musculus Mammary Glands, Animal | Cells, Cultured
5 genes: ACOX2 | BCL2L11 | CDKN1A | CDKN1B | MTOR
1
5. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole regulation of membrane permeability Glucose 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Glucose affects regulation of membrane permeability] 2: Homo sapiens | Mus musculus Brain | Microvessels | Endothelial Cells | Cells, Cultured   1
6. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole cell proliferation cobaltous chloride 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [cobaltous chloride results in decreased cell proliferation] 1: Mus musculus Retina | Cell Line, Transformed
5 genes: BAX | BCL2 | EPO | TP53 | VEGFA
1
7. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole apoptotic process cobaltous chloride [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole co-treated with cobaltous chloride] results in increased apoptotic process 1: Mus musculus Retina | Cell Line, Transformed
9 genes: APAF1 | BAX | BCL2 | BID | CASP3 | CYCS | EPO | TP53 | TRP53
1
8. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole cell proliferation 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole results in decreased cell proliferation 1: Mus musculus Retina | Cell Line, Transformed
5 genes: BAX | BCL2 | EPO | TP53 | VEGFA
1
9. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole cell proliferation Oxygen 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Oxygen deficiency results in decreased cell proliferation] 1: Mus musculus Retina | Cell Line, Transformed
5 genes: BAX | BCL2 | EPO | TP53 | VEGFA
1
10. 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole vasoconstriction Nitric Oxide | Phenylephrine 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole inhibits the reaction [Nitric Oxide inhibits the reaction [Phenylephrine results in increased vasoconstriction]] 1: Rattus norvegicus Aorta   1
11. 7-nitroindazole cell death trimethyltin 7-nitroindazole inhibits the reaction [trimethyltin results in increased cell death] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured   1
12. 7-nitroindazole apoptotic process NOS1 [7-nitroindazole results in decreased activity of NOS1 protein] which results in decreased apoptotic process 1: Canis lupus familiaris Dentate Gyrus | Neurons
4 genes: CASP3 | GAPDH | SIAH1A | TP53
1
13. 7-nitroindazole cell death 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 7-nitroindazole inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased cell death] 1: Danio rerio Diencephalon | Dopaminergic Neurons   1
14. 7-nitroindazole cell proliferation cobaltous chloride 7-nitroindazole inhibits the reaction [cobaltous chloride results in decreased cell proliferation] 1: Rattus norvegicus PC12 Cells 1 gene: TP53 1
15. 7-nitroindazole inorganic cation transmembrane transport 7-nitroindazole results in increased inorganic cation transmembrane transport 1: Mus musculus Kidney | Epithelial Cells | Cell Line   1
16. 7-nitroindazole inorganic cation transmembrane transport Rubidium [7-nitroindazole results in increased inorganic cation transmembrane transport] which results in increased uptake of Rubidium 1: Mus musculus Kidney | Epithelial Cells | Cell Line   1
17. 7-nitroindazole positive regulation of reactive oxygen species biosynthetic process Staurosporine 7-nitroindazole inhibits the reaction [Staurosporine results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Gallus gallus Retinal Neurons | Cells, Cultured   1
18. 7-nitroindazole positive regulation of apoptotic DNA fragmentation Staurosporine 7-nitroindazole inhibits the reaction [Staurosporine results in increased positive regulation of apoptotic DNA fragmentation] 1: Gallus gallus Retinal Neurons | Cells, Cultured   1
19. 7-nitroindazole cell death Paraquat 7-nitroindazole inhibits the reaction [Paraquat results in increased cell death] 1: Homo sapiens Neurons | Cell Line, Tumor   1
20. 7-nitroindazole cell proliferation Paraquat 7-nitroindazole inhibits the reaction [Paraquat results in decreased cell proliferation] 1: Homo sapiens Neurons | Cell Line, Tumor 1 gene: TP53 1
21. 7-nitroindazole nitric oxide biosynthetic process Paraquat 7-nitroindazole inhibits the reaction [Paraquat results in increased nitric oxide biosynthetic process] 1: Homo sapiens Neurons | Cell Line, Tumor 1 gene: NOS1 1
22. 7-nitroindazole protein modification process Paraquat 7-nitroindazole inhibits the reaction [Paraquat results in increased protein modification process] 1: Homo sapiens Neurons | Cell Line, Tumor   1
23. 7-nitroindazole DNA damage response, detection of DNA damage Paraquat 7-nitroindazole inhibits the reaction [Paraquat results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Neurons | Cell Line, Tumor   1
24. 7-nitroindazole nitric-oxide synthase activity Paraquat 7-nitroindazole inhibits the reaction [Paraquat results in increased nitric-oxide synthase activity] 1: Homo sapiens Neurons | Cell Line, Tumor 1 gene: NOS1 1
25. A 443654 positive regulation of cell death A 443654 results in increased positive regulation of cell death 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor   1
26. A 443654 positive regulation of cell death A 443654 results in increased positive regulation of cell death 1: Mus musculus Mammary Glands, Animal | Cells, Cultured   1
27. Axitinib cell proliferation Axitinib results in decreased cell proliferation 1: Homo sapiens Human Umbilical Vein Endothelial Cells 1 gene: VEGFA 1
28. Axitinib apoptotic process Axitinib affects apoptotic process 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: PAK1 1
29. Axitinib cell proliferation Axitinib affects cell proliferation 1: Rattus norvegicus Neuroglia | Cell Line, Tumor 1 gene: VEGFA 1
30. Axitinib cell chemotaxis VEGFA Axitinib inhibits the reaction [VEGFA protein results in increased cell chemotaxis] 1: Homo sapiens Human Umbilical Vein Endothelial Cells 1 gene: VEGFA 1
31. Axitinib cell proliferation VEGFA Axitinib inhibits the reaction [VEGFA protein results in increased cell proliferation] 1: Homo sapiens Human Umbilical Vein Endothelial Cells 1 gene: VEGFA 1
32. Axitinib regulation of vascular permeability VEGFA Axitinib inhibits the reaction [VEGFA protein affects regulation of vascular permeability] 1: Mus musculus Blood Vessels   1
33. Axitinib ATP biosynthetic process Axitinib results in decreased ATP biosynthetic process 1: Homo sapiens Hepatocytes | Cells, Cultured   1
34. Axitinib activation of cysteine-type endopeptidase activity involved in apoptotic process Axitinib results in increased activation of cysteine-type endopeptidase activity involved in apoptotic process 1: Rattus norvegicus Hepatocytes | Cells, Cultured   1
35. Granisetron ion transport Estramustine Granisetron affects the reaction [Estramustine affects ion transport] 1: Homo sapiens Neuroglia | Cell Line
2 genes: HTR3A | SLC22A2
1
36. Granisetron apoptotic process Granisetron results in increased apoptotic process 1: Homo sapiens Fetus | Heart | Cells, Cultured 1 gene: ADRA1A 1
37. Granisetron cell death Tretinoin [Granisetron co-treated with Tretinoin] results in increased cell death 1: Homo sapiens Lung | Cell Line, Tumor   1
38. GSK343 positive regulation of apoptotic process GSK343 results in increased positive regulation of apoptotic process 1: Homo sapiens Ovary | Epithelial Cells | Tumor Cells, Cultured   1
39. GSK343 cell growth GSK343 results in decreased cell growth 1: Homo sapiens Ovary | Epithelial Cells | Tumor Cells, Cultured   1
40. GSK343 histone-lysine N-methyltransferase activity GSK343 results in decreased histone-lysine N-methyltransferase activity 1: Homo sapiens Ovary | Epithelial Cells | Tumor Cells, Cultured 1 gene: EZH2 1
41. GSK343 histone-lysine N-methyltransferase activity GSK343 results in decreased histone-lysine N-methyltransferase activity 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: EZH2 1
42. GSK343 positive regulation of histone H3-K27 trimethylation GSK343 results in decreased positive regulation of histone H3-K27 trimethylation 1: Homo sapiens MCF-7 Cells   1
43. Indazoles positive regulation of retinoic acid receptor signaling pathway Indazoles analog results in increased positive regulation of retinoic acid receptor signaling pathway 1: Mus musculus Embryo, Mammalian | Fibroblasts | Cell Line   1
44. lonidamine positive regulation of apoptotic process Arsenic Trioxide [Arsenic Trioxide co-treated with lonidamine] results in increased positive regulation of apoptotic process 1: Homo sapiens Cell Line, Tumor
9 genes: AKT1 | BAX | BCL2L1 | BID | CASP3 | CASP8 | CASP9 | HTRA2 | RPS6
1
45. lonidamine positive regulation of apoptotic process Curcumin [Curcumin co-treated with lonidamine] results in increased positive regulation of apoptotic process 1: Homo sapiens Cell Line, Tumor
9 genes: AKT1 | BAX | BCL2L1 | BID | CASP3 | CASP8 | CASP9 | HTRA2 | RPS6
1
46. lonidamine positive regulation of apoptotic process TNF [TNF protein co-treated with lonidamine] results in increased positive regulation of apoptotic process 1: Homo sapiens Cell Line, Tumor
9 genes: AKT1 | BAX | BCL2L1 | BID | CASP3 | CASP8 | CASP9 | HTRA2 | RPS6
1
47. lonidamine positive regulation of cAMP-dependent protein kinase activity lonidamine results in increased positive regulation of cAMP-dependent protein kinase activity 1: Homo sapiens Cell Line, Tumor   1
48. lonidamine positive regulation of cAMP-dependent protein kinase activity Arsenic Trioxide Arsenic Trioxide inhibits the reaction [lonidamine results in increased positive regulation of cAMP-dependent protein kinase activity] 1: Homo sapiens Cell Line, Tumor   1
49. lonidamine cell proliferation lonidamine results in decreased cell proliferation 1: Rattus norvegicus Testis | Germ Cells
4 genes: AKT1 | BAX | BCL2 | BCL2L1
1
50. N-(1-adamantyl)-1-pentylindazole-3-carboxamide drug metabolic process NAD [NAD results in increased drug metabolic process] which results in increased oxidation of N-(1-adamantyl)-1-pentylindazole-3-carboxamide metabolite 1: Homo sapiens Liver | Cytosol   1
1–50 of 57 results.