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Chemical Indoles

1–50 of 3,523 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10-(2-(5H-(1,2,4)triazino(5,6-b)indol-3-ylthio)butanoyl)-10H-phenothiazine cell proliferation resveratrol | Sodium Fluoride 10-(2-(5H-(1,2,4)triazino(5,6-b)indol-3-ylthio)butanoyl)-10H-phenothiazine inhibits the reaction [resveratrol inhibits the reaction [Sodium Fluoride results in decreased cell proliferation]] 1: Mus musculus Ameloblasts | Cell Line   1
2. 10-decarbamoylmitomycin C apoptotic process 10-decarbamoylmitomycin C results in increased apoptotic process 1: Homo sapiens Cell Line, Tumor
4 genes: CASP3 | CASP9 | CHEK1 | TP53
1
3. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons   1
4. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane locomotory behavior 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased locomotory behavior] 1: Mus musculus  
2 genes: SLC6A3 | TH
1
5. 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons
3 genes: CASP1 | IL1A | TLR4
1
6. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
7. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration NR4A1 NR4A1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
8. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane DNA damage response, detection of DNA damage 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: PARP1 1
9. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration TGFB1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [TGFB1 protein results in increased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
10. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Pancreas | Cell Line, Tumor   1
11. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons
3 genes: ATF4 | CASP3 | DDIT3
1
12. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation NR4A1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane affects the reaction [NR4A1 protein affects cell proliferation] 1: Homo sapiens Pancreas | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
13. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons 1 gene: CASP8 1
14. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell migration ITGB1 ITGB1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell migration] 1: Homo sapiens Breast | Cell Line, Tumor
3 genes: ITGB1 | RPS6KB1 | TGFB1
1
15. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell adhesion FN1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [FN1 protein results in increased cell adhesion] 1: Homo sapiens MCF-7 Cells
2 genes: ITGB1 | ITGB3
1
16. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane calcium ion homeostasis 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane affects calcium ion homeostasis 1: Homo sapiens Pancreas | Cell Line, Tumor   1
17. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane apoptotic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased apoptotic process 1: Homo sapiens Pancreas | Cell Line, Tumor
12 genes: BCL2 | BID | BIRC5 | CASP3 | CASP7 | CASP8 | DDIT3 | EP300 | NR4A1 | PARP1 | RPS6KB1 | XBP1
1
18. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell adhesion FN1 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [FN1 protein results in increased cell adhesion] 1: Homo sapiens Breast | Cell Line, Tumor
2 genes: ITGB1 | ITGB3
1
19. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process Glutathione Glutathione inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens Pancreas | Cell Line, Tumor   1
20. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation NR4A1 NR4A1 protein affects the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation] 1: Homo sapiens Kidney | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
21. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation 1: Homo sapiens Kidney | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
22. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane reactive oxygen species biosynthetic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Kidney | Cell Line, Tumor   1
23. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane cell proliferation 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor
4 genes: AXIN2 | BCL2 | EGFR | TGFB1
1
24. 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane apoptotic process 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased apoptotic process 1: Homo sapiens Kidney | Cell Line, Tumor
12 genes: BCL2 | BID | BIRC5 | CASP3 | CASP7 | CASP8 | DDIT3 | EP300 | NR4A1 | PARP1 | RPS6KB1 | XBP1
1
25. 1,1-bis(3'-indolyl)-1-(p-anisyl)methane positive regulation of neuron apoptotic process 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of neuron apoptotic process] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons   1
26. 1,1-bis(3'-indolyl)-1-(p-anisyl)methane positive regulation of I-kappaB kinase/NF-kappaB signaling 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased positive regulation of I-kappaB kinase/NF-kappaB signaling] 1: Mus musculus Substantia Nigra | Dopaminergic Neurons 1 gene: IL1A 1
27. 1,1-bis(3'-indolyl)-1-(p-anisyl)methane locomotory behavior 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Probenecid 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased locomotory behavior] 1: Mus musculus  
2 genes: SLC6A3 | TH
1
28. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy Acetylcysteine | gemcitabine Acetylcysteine inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
29. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy gemcitabine [gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
30. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy chloroquine diphosphate | gemcitabine chloroquine diphosphate inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
31. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy 3-methyladenine | gemcitabine 3-methyladenine inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
32. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole cell proliferation gemcitabine [gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor   1
33. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid autophagosome maturation Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased autophagosome maturation] 1: Mus musculus Coronary Vessels | Muscle Cells   1
34. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid microtubule motor activity Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased microtubule motor activity] 1: Mus musculus Coronary Vessels | Muscle Cells   1
35. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog results in increased acrosome reaction 1: Mus musculus Spermatozoa   1
36. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction NAADP 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog affects the reaction [NAADP results in increased acrosome reaction] 1: Mus musculus Spermatozoa   1
37. 1-(4-chlorobenzoyl)-5-methoxy-2-1H-indole-3-acetic acid 3-(nitrooxymethyl)phenyl ester apoptotic process Celecoxib 1-(4-chlorobenzoyl)-5-methoxy-2-1H-indole-3-acetic acid 3-(nitrooxymethyl)phenyl ester inhibits the reaction [Celecoxib results in increased apoptotic process] 1: Cavia Gastric Mucosa | Cells, Cultured   1
38. 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine leukocyte degranulation N-Formylmethionine Leucyl-Phenylalanine 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased leukocyte degranulation] 1: Homo sapiens Granulocytes   1
39. 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine histamine secretion Trinitrobenzenesulfonic Acid 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased histamine secretion] 1: Rattus norvegicus Colon   1
40. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole positive regulation of cell division 1-(5-fluoropentyl)-3-(1-naphthoyl)indole results in decreased positive regulation of cell division 1: Homo sapiens Lymphocytes | Cells, Cultured   1
41. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole positive regulation of cell division 1-(5-fluoropentyl)-3-(1-naphthoyl)indole analog results in decreased positive regulation of cell division 1: Homo sapiens Lymphocytes | Cells, Cultured   1
42. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole positive regulation of neuron apoptotic process 1-(5-fluoropentyl)-3-(1-naphthoyl)indole affects positive regulation of neuron apoptotic process 1: Mus musculus Prosencephalon | Neurons | Cells, Cultured   1
43. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole cellular response to toxic substance AM 251 | CNR1 [AM 251 binds to and results in decreased activity of CNR1 protein] inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole affects cellular response to toxic substance] 1: Mus musculus Prosencephalon | Neurons | Cells, Cultured   1
44. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole positive regulation of neuron death AM 251 | CNR1 [AM 251 binds to and results in decreased activity of CNR1 protein] inhibits the reaction [1-(5-fluoropentyl)-3-(1-naphthoyl)indole affects positive regulation of neuron death] 1: Mus musculus Prosencephalon | Neurons | Cells, Cultured   1
45. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole cellular response to toxic substance 1-(5-fluoropentyl)-3-(1-naphthoyl)indole affects cellular response to toxic substance 1: Mus musculus Prosencephalon | Neurons | Cells, Cultured   1
46. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole positive regulation of glutamate secretion, neurotransmission 1-(5-fluoropentyl)-3-(1-naphthoyl)indole results in increased positive regulation of glutamate secretion, neurotransmission 1: Mus musculus Hippocampus   1
47. 1-(5-fluoropentyl)-3-(1-naphthoyl)indole drug metabolic process NADP [NADP results in increased drug metabolic process] which results in increased hydroxylation of 1-(5-fluoropentyl)-3-(1-naphthoyl)indole 1: Homo sapiens Microsomes, Liver   1
48. (1-(5-hydropentyl)indol-3-yl)-(1-naphthyl)methanone drug metabolic process fomepizole | NAD fomepizole inhibits the reaction [[NAD results in increased drug metabolic process] which results in increased oxidation of (1-(5-hydropentyl)indol-3-yl)-(1-naphthyl)methanone] 1: Homo sapiens Liver | Cytosol   1
49. (1-(5-hydropentyl)indol-3-yl)-(1-naphthyl)methanone drug metabolic process NADP [NADP results in increased drug metabolic process] which results in increased hydroxylation of (1-(5-hydropentyl)indol-3-yl)-(1-naphthyl)methanone 1: Homo sapiens Microsomes, Liver   1
50. (1-(5-hydropentyl)indol-3-yl)-(1-naphthyl)methanone drug metabolic process NAD [NAD results in increased drug metabolic process] which results in increased oxidation of (1-(5-hydropentyl)indol-3-yl)-(1-naphthyl)methanone 1: Homo sapiens Liver | Cytosol   1
1–50 of 3,523 results.