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Chemical Insulin-Like Growth Factor I

Name Insulin-Like Growth Factor I
CAS Type 1 Name Insulin-like growth factor I
Equivalent Terms IGF-1 | IGF-I | IGF-I-SmC | Insulin Like Growth Factor I | Insulin Like Somatomedin Peptide I | Insulin-Like Somatomedin Peptide I | Somatomedin C
CAS Registry Number 67763-96-6
Definition A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D007334
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Somatomedins Insulin-Like Growth Factor I

Top ↑ Descendants

Insulin-Like Growth Factor I
  cementum-derived growth factor, 14-kDa
  Growth Factors, Combined Defect of
  human insulin-like-growth-factor-I (21-40)
  IGF1 protein, human
  IGF1RA protein, zebrafish
  IGF-I-IGFBP-3 complex
  insulin, A(27)-B-insulin-like growth factor I
  insulin-like growth factor 1A prohormone (91-103)
  insulin-like growth factor 1, des-(1-3)-
  insulin-like growth factor-1 D peptide
  insulin-like growth factor-1, mouse
  insulin-like growth factor-1, rat
  insulin like growth factor I (1-27)-Gly-Gly-Gly-Gly-(38-70)
  insulin-like growth factor I (24-41)
  insulin-like growth factor I (57-70)
  Insulin-Like Growth Factor I Deficiency
  insulin-like growth factor I, Gln(3)-Ala(4)-Tyr(15)-Leu(16)-
  insulin-like growth factor I, N-Ala-Glu-
  insulin-like growth factor I, N-methionyl-
  insulin-like growth factor I-Pseudomonas exotoxin A (40)
  insulin-like growth factor I, Thr(59)-
  insulin-like growth factor I, Val(59)-
  long R(3)-insulin-like growth factor-I
  mechano-growth factor E, human
  mechano-growth factor, mouse
  mechano-growth factor, rat
  Nalpha(Gly1)-((2-6-(biotinamido)-2-(4-azidobenzamido)hexanoamido)ethyl-1.'-dithiopropionyl)-insulin-like growth factor-1
  Nalpha(Gly1)-(4-azidobenzoyl)-insulin-like growth factor-1
  preproinsulin-like growth factor I
  pro-insulin-like growth factor I