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Chemical Insulin-Like Growth Factor I

Name Insulin-Like Growth Factor I
CAS Type 1 Name Insulin-like growth factor I
Equivalent Terms IGF-1 | IGF-I | IGF-I-SmC | Insulin Like Growth Factor I | Insulin Like Somatomedin Peptide I | Insulin-Like Somatomedin Peptide I | Somatomedin C
CAS Registry Number 67763-96-6
Definition A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D007334
External Links

Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Has associated phenotype references Somatomedins Insulin-Like Growth Factor I

Top ↑ Descendants

Insulin-Like Growth Factor I
  cementum-derived growth factor, 14-kDa
  Growth Factors, Combined Defect of
  human insulin-like-growth-factor-I (21-40)
  IGF1 protein, human
  IGF1RA protein, zebrafish
  IGF-I-IGFBP-3 complex
  insulin, A(27)-B-insulin-like growth factor I
  insulin-like growth factor 1A prohormone (91-103)
  insulin-like growth factor 1, des-(1-3)-
  insulin-like growth factor-1 D peptide
  insulin-like growth factor-1, mouse
  insulin-like growth factor-1, rat
  insulin like growth factor I (1-27)-Gly-Gly-Gly-Gly-(38-70)
  insulin-like growth factor I (24-41)
  insulin-like growth factor I (57-70)
  Insulin-Like Growth Factor I Deficiency
  insulin-like growth factor I, Gln(3)-Ala(4)-Tyr(15)-Leu(16)-
  insulin-like growth factor I, N-Ala-Glu-
  insulin-like growth factor I, N-methionyl-
  insulin-like growth factor I-Pseudomonas exotoxin A (40)
  insulin-like growth factor I, Thr(59)-
  insulin-like growth factor I, Val(59)-
  long R(3)-insulin-like growth factor-I
  mechano-growth factor E, human
  mechano-growth factor, mouse
  mechano-growth factor, rat
  Nalpha(Gly1)-((2-6-(biotinamido)-2-(4-azidobenzamido)hexanoamido)ethyl-1.'-dithiopropionyl)-insulin-like growth factor-1
  Nalpha(Gly1)-(4-azidobenzoyl)-insulin-like growth factor-1
  preproinsulin-like growth factor I
  pro-insulin-like growth factor I