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Chemical Kininogens

Name Kininogens
Equivalent Terms Cystatins, Kininogen | Kininogen | Kininogen Cystatins | Prekinins | Prokinins | Thiostatin | T Kininogen | T-Kininogen
Definition Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D007704
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Blood Coagulation Factors Has associated genes Has associated diseases Has associated exposure references Kininogens
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Inflammation Mediators Has associated genes Has associated diseases Has associated exposure references Autacoids Has associated genes Has associated diseases Has associated exposure references Kinins Has associated genes Has associated diseases Kininogens
3. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Kinins Has associated genes Has associated diseases Kininogens

Top ↑ Descendants

Kininogens
  alpha-thiol proteinase inhibitor
  kininogen 1, human
  Kininogen Deficiency, High Molecular Weight and Low Molecular Weight
View node Kininogen, High-Molecular-Weight
  Kininogen, Low-Molecular-Weight
  leucyl-asparaginyl-alanyl-glutamyl-asparaginyl-asparaginyl-alanine
  PU-15 protein, synthetic
  PU-D1 peptide