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Chemical Lactones

1–50 of 2,225 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 12-acetoxyhawtriwaic acid lactone sensory perception of pain TAC1 12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain] 1: Mus musculus Hindlimb   1
2. 12-acetoxyhawtriwaic acid lactone sensory perception of pain TAC1 | Theophylline Theophylline inhibits the reaction [12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain]] 1: Mus musculus Hindlimb   1
3. 12-acetoxyhawtriwaic acid lactone sensory perception of pain Glyburide | TAC1 Glyburide inhibits the reaction [12-acetoxyhawtriwaic acid lactone inhibits the reaction [TAC1 protein results in increased sensory perception of pain]] 1: Mus musculus Hindlimb   1
4. 12-acetoxyhawtriwaic acid lactone positive regulation of neutrophil chemotaxis Tetradecanoylphorbol Acetate 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased positive regulation of neutrophil chemotaxis] 1: Mus musculus Ear | Neutrophils   1
5. 22,23-dihydroavermectin B(1)a positive regulation of cell death 22,23-dihydroavermectin B(1)a results in increased positive regulation of cell death 1: Homo sapiens HEK293 Cells   1
6. 22,23-dihydroavermectin B(1)a positive regulation of nuclear receptor transcription coactivator activity Chenodeoxycholic Acid 22,23-dihydroavermectin B(1)a inhibits the reaction [Chenodeoxycholic Acid results in increased positive regulation of nuclear receptor transcription coactivator activity] 1: Homo sapiens HEK293 Cells   1
7. 2,3-bis(3'-hydroxybenzyl)butyrolactone triglyceride metabolic process 2,3-bis(3'-hydroxybenzyl)butyrolactone affects triglyceride metabolic process 1: Homo sapiens Serum
3 genes: GPAT4 | INSIG1 | SLC37A4
1
8. 2,3-bis(3'-hydroxybenzyl)butyrolactone cellular response to X-ray 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: DBN1 1
9. 2,3-bis(3'-hydroxybenzyl)butyrolactone cellular response to X-ray mitotic cell cycle arrest [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased mitotic cell cycle arrest 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: DBN1 1
10. 2,3-bis(3'-hydroxybenzyl)butyrolactone mitotic cell cycle arrest cellular response to X-ray [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased mitotic cell cycle arrest 1: Homo sapiens Breast | Cell Line, Tumor
4 genes: CDKN1A | DDIAS | DUSP1 | GADD45A
1
11. 2,3-bis(3'-hydroxybenzyl)butyrolactone apoptotic process cellular response to X-ray [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased apoptotic process 1: Homo sapiens Breast | Cell Line, Tumor
50 genes: BAG3 | BCL2 | BCL2L12 | BEX2 | BIRC5 | BMF | BRAT1 | BRCA1 | BUB1B | CADM1 | CDK1 | CHEK1 | CHEK2 | CSE1L | CSRNP2 | DDIAS | ESPL1 | FOXO3 | G2E3 | GADD45A | GULP1 | IFIT2 | ITGB3BP | ITPR1 | LGALS1 | LMNB1 | MCM2 | MEF2A | MELK | MKNK2 | MOAP1 | MTFP1 | PARP1 | PAWR | PDCD4 | PDCD6IP | PHLDA2 | PPIF | RAD21 | RRAGC | SH3KBP1 | SQSTM1 | TGFBR1 | TIGAR | TNFAIP1 | TNFRSF12A | TNFRSF21 | TP53INP1 | TPX2 | ZC3H12A
1
12. 2,3-bis(3'-hydroxybenzyl)butyrolactone cellular response to X-ray apoptotic process [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased apoptotic process 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: DBN1 1
13. 2,3-bis(3'-hydroxybenzyl)butyrolactone cellular response to X-ray DNA damage response, detection of DNA damage [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: DBN1 1
14. 2,3-bis(3'-hydroxybenzyl)butyrolactone DNA damage response, detection of DNA damage cellular response to X-ray [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Breast | Cell Line, Tumor
15 genes: MRPS26 | PARP1 | PCNA | POLD1 | POLD2 | POLD3 | RFC2 | RFC3 | RFC4 | RFC5 | RPA1 | RPA3 | SOX4 | UBE2B | USP1
1
15. 2,3-bis(3'-hydroxybenzyl)butyrolactone cellular response to X-ray micronucleus organization [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased micronucleus organization 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: DBN1 1
16. 2,3-bis(3'-hydroxybenzyl)butyrolactone micronucleus organization cellular response to X-ray [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased micronucleus organization 1: Homo sapiens Breast | Cell Line, Tumor   1
17. 2,3-bis(3'-hydroxybenzyl)butyrolactone cellular response to X-ray chromosome breakage [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased chromosome breakage 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: DBN1 1
18. 2,3-bis(3'-hydroxybenzyl)butyrolactone chromosome breakage cellular response to X-ray [2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased cellular response to X-ray] which results in increased chromosome breakage 1: Homo sapiens Breast | Cell Line, Tumor   1
19. 2,3-bis(3'-hydroxybenzyl)butyrolactone thelarche Phenols [Phenols results in increased abundance of 2,3-bis(3'-hydroxybenzyl)butyrolactone] which results in decreased thelarche 1: Homo sapiens Breast   1
20. 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3H)-one leukocyte migration involved in inflammatory response lipopolysaccharide, E coli O55-B5 | Metformin 3-benzyl-5-((2-nitrophenoxy)methyl)dihydrofuran-2(3H)-one inhibits the reaction [Metformin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased leukocyte migration involved in inflammatory response]] 1: Mus musculus Lung   1
21. 4-acetylantroquinonol B cell death 4-acetylantroquinonol B results in increased cell death 1: Homo sapiens Colon | Cell Line, Tumor   1
22. 4-acetylantroquinonol B cell death Fluorouracil 4-acetylantroquinonol B promotes the reaction [Fluorouracil results in increased cell death] 1: Homo sapiens Colon | Cell Line, Tumor   1
23. 4-acetylantroquinonol B positive regulation of stem cell population maintenance 4-acetylantroquinonol B results in decreased positive regulation of stem cell population maintenance 1: Homo sapiens Colon | Cell Line, Tumor 1 gene: NANOG 1
24. 4-acetylantroquinonol B positive regulation of cell migration 4-acetylantroquinonol B results in decreased positive regulation of cell migration 1: Homo sapiens Colon | Cell Line, Tumor
2 genes: JAK2 | STAT3
1
25. 4-acetylantroquinonol B positive regulation of cell proliferation 4-acetylantroquinonol B results in decreased positive regulation of cell proliferation 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor
7 genes: CTNNB1 | EZH2 | JAK2 | NANOG | SMO | STAT3 | SUZ12
1
26. 4-acetylantroquinonol B positive regulation of autophagy 4-acetylantroquinonol B results in decreased positive regulation of autophagy 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor
2 genes: ATG7 | GSK3B
1
27. 4-acetylantroquinonol B protein lipidation involved in autophagosome assembly 4-acetylantroquinonol B results in decreased protein lipidation involved in autophagosome assembly 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor 1 gene: ATG5 1
28. 4-acetylantroquinonol B activation of protein kinase B activity 4-acetylantroquinonol B results in decreased activation of protein kinase B activity 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor
2 genes: MTOR | SRC
1
29. 4-acetylantroquinonol B positive regulation of apoptotic process 4-acetylantroquinonol B results in increased positive regulation of apoptotic process 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor
5 genes: ATG7 | CTNNB1 | GSK3B | JAK2 | SRC
1
30. 4-acetylantroquinonol B response to antineoplastic agent 4-acetylantroquinonol B results in increased response to antineoplastic agent 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor   1
31. 4-acetylantroquinonol B response to antineoplastic agent Cisplatin [4-acetylantroquinonol B results in increased response to antineoplastic agent] which results in increased susceptibility to Cisplatin 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor   1
32. 4-acetylantroquinonol B positive regulation of cell death Cisplatin 4-acetylantroquinonol B promotes the reaction [Cisplatin results in increased positive regulation of cell death] 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor 1 gene: MTOR 1
33. 4-acetylantroquinonol B protein lipidation involved in autophagosome assembly Cisplatin 4-acetylantroquinonol B promotes the reaction [Cisplatin results in increased protein lipidation involved in autophagosome assembly] 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor 1 gene: ATG5 1
34. 4-acetylantroquinonol B positive regulation of cell proliferation ATG5 ATG5 protein inhibits the reaction [4-acetylantroquinonol B results in decreased positive regulation of cell proliferation] 1: Homo sapiens Ovary | Epithelium | Cell Line, Tumor
7 genes: CTNNB1 | EZH2 | JAK2 | NANOG | SMO | STAT3 | SUZ12
1
35. 4-acetylantroquinonol B positive regulation of apoptotic process ATG5 ATG5 protein inhibits the reaction [4-acetylantroquinonol B results in increased positive regulation of apoptotic process] 1: Homo sapiens Ovary | Epithelium | Cell Line, Tumor
5 genes: ATG7 | CTNNB1 | GSK3B | JAK2 | SRC
1
36. 4-acetylantroquinonol B positive regulation of cell death Cisplatin Cisplatin promotes the reaction [4-acetylantroquinonol B results in increased positive regulation of cell death] 1: Homo sapiens Ovary | Epithelial Cells | Cell Line, Tumor 1 gene: MTOR 1
37. 4-hydroxy-7-oxo-5-heptenoic acid lactone endothelial tube morphogenesis 4-hydroxy-7-oxo-5-heptenoic acid lactone results in increased endothelial tube morphogenesis 1: Homo sapiens Human Umbilical Vein Endothelial Cells | Cells, Cultured   1
38. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of reactive oxygen species biosynthetic process 4-hydroxy-7-oxo-5-heptenoic acid lactone results in increased positive regulation of reactive oxygen species biosynthetic process 1: Homo sapiens Retinal Pigment Epithelium | Cell Line   1
39. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of cell proliferation 4-hydroxy-7-oxo-5-heptenoic acid lactone results in increased positive regulation of cell proliferation 1: Homo sapiens Retinal Pigment Epithelium | Cell Line 1 gene: VEGFA 1
40. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of cell death 4-hydroxy-7-oxo-5-heptenoic acid lactone results in increased positive regulation of cell death 1: Homo sapiens Retinal Pigment Epithelium | Cell Line   1
41. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of endothelial cell migration 4-hydroxy-7-oxo-5-heptenoic acid lactone results in increased positive regulation of endothelial cell migration 1: Homo sapiens Human Umbilical Vein Endothelial Cells | Cells, Cultured 1 gene: VEGFA 1
42. 4-hydroxy-7-oxo-5-heptenoic acid lactone glutathione metabolic process 4-hydroxy-7-oxo-5-heptenoic acid lactone affects glutathione metabolic process 1: Homo sapiens Retinal Pigment Epithelium | Cell Line   1
43. 4-hydroxy-7-oxo-5-heptenoic acid lactone glutathione metabolic process Glutathione [4-hydroxy-7-oxo-5-heptenoic acid lactone affects glutathione metabolic process] which results in decreased abundance of Glutathione 1: Homo sapiens Retinal Pigment Epithelium | Cell Line   1
44. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of reactive oxygen species biosynthetic process Acetylcysteine Acetylcysteine inhibits the reaction [4-hydroxy-7-oxo-5-heptenoic acid lactone results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Homo sapiens Retinal Pigment Epithelium | Cell Line   1
45. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of endothelial cell proliferation Glutathione [Glutathione binds to 4-hydroxy-7-oxo-5-heptenoic acid lactone] which results in increased positive regulation of endothelial cell proliferation 1: Homo sapiens Human Umbilical Vein Endothelial Cells | Cells, Cultured 1 gene: VEGFA 1
46. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of endothelial cell migration Glutathione [Glutathione binds to 4-hydroxy-7-oxo-5-heptenoic acid lactone] which results in increased positive regulation of endothelial cell migration 1: Homo sapiens Human Umbilical Vein Endothelial Cells | Cells, Cultured 1 gene: VEGFA 1
47. 4-hydroxy-7-oxo-5-heptenoic acid lactone endothelial tube morphogenesis Glutathione [Glutathione binds to 4-hydroxy-7-oxo-5-heptenoic acid lactone] which results in increased endothelial tube morphogenesis 1: Homo sapiens Human Umbilical Vein Endothelial Cells | Cells, Cultured   1
48. 4-hydroxy-7-oxo-5-heptenoic acid lactone fatty acid oxidation Docosahexaenoic Acids | Oxidants [[Oxidants results in increased fatty acid oxidation] which results in increased oxidation of Docosahexaenoic Acids] which results in increased chemical synthesis of 4-hydroxy-7-oxo-5-heptenoic acid lactone     1
49. 4-hydroxy-7-oxo-5-heptenoic acid lactone positive regulation of angiogenesis 2-(omega-carboxyethyl)pyrrole | Amines [[4-hydroxy-7-oxo-5-heptenoic acid lactone co-treated with Amines] results in increased chemical synthesis of 2-(omega-carboxyethyl)pyrrole analog] which results in increased positive regulation of angiogenesis  
5 genes: C3 | C5 | HMOX1 | NFE2L2 | VEGFA
1
50. 4-hydroxy-7-oxo-5-heptenoic acid lactone glutathione biosynthetic process 4-hydroxy-7-oxo-5-heptenoic acid lactone results in decreased glutathione biosynthetic process 1: Homo sapiens Retinal Pigment Epithelium | Cell Line   1
1–50 of 2,225 results.