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Chemical Gonadotropin-Releasing Hormone

Name Gonadotropin-Releasing Hormone
CAS Type 1 Name 5-oxoPro-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (human or pig)
Equivalent Terms Cystorelin | Dirigestran | Factrel | FSH Releasing Hormone | FSH-Releasing Hormone | GnRH | Gn-RH | Gonadoliberin | Gonadorelin | Gonadorelin Acetate | Gonadorelin Hydrochloride | Gonadotropin Releasing Hormone | Kryptocur | LFRH | LH FSH Releasing Hormone | LH-FSH Releasing Hormone | LHFSH Releasing Hormone | LHFSHRH | LH Releasing Hormone | LH-Releasing Hormone | LHRH | LH-RH | Luliberin | Luteinizing Hormone Releasing Hormone | Luteinizing Hormone-Releasing Hormone | Releasing Hormone, LHFSH
CAS Registry Number 33515-09-2
Definition A decapeptide that stimulates the synthesis and secretion of both pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE. GnRH is produced by neurons in the septum PREOPTIC AREA of the HYPOTHALAMUS and released into the pituitary portal blood, leading to stimulation of GONADOTROPHS in the ANTERIOR PITUITARY GLAND.
Structure Gonadotropin-Releasing Hormone
Top Interacting
Genes
MeSH® ID D007987
External Links

Top ↑ Ancestors

1. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Hypothalamic Hormones Has associated genes Has associated diseases Pituitary Hormone-Releasing Hormones Has associated genes Has associated diseases Gonadotropin-Releasing Hormone Has associated genes Has associated diseases
2. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Neuropeptides Has associated genes Has associated diseases Hypothalamic Hormones Has associated genes Has associated diseases Pituitary Hormone-Releasing Hormones Has associated genes Has associated diseases Gonadotropin-Releasing Hormone Has associated genes Has associated diseases
3. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Oligopeptides Has associated genes Has associated diseases Gonadotropin-Releasing Hormone Has associated genes Has associated diseases
4. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Hypothalamic Hormones Has associated genes Has associated diseases Pituitary Hormone-Releasing Hormones Has associated genes Has associated diseases Gonadotropin-Releasing Hormone Has associated genes Has associated diseases

Top ↑ Descendants

Gonadotropin-Releasing Hormone Has associated genes Has associated diseases
  5-oxo-pro-his-trp-ser-tyr-gly-trp-leu-pro-glynh2
  9-hydroxyproline-gonadorelin
  A 76154
  AEZS-125
  AN 207
  argtide
  azaline
  azo-GnRH tetanus toxoid conjugate
  azo-LHRH-bovine serum albumin conjugate
  azo-LHRH-tetanus toxoid conjugate
  (beta-Asp(alpha-DEA))(6),Gln(8)-GnRH
  BIM 21009
  bovine serum albumin-LHRH conjugate
  Buserelin Has associated genes Has associated diseases
  Cerebellar Ataxia and Hypogonadotropic Hypogonadism
  cetrorelix Has associated genes Has associated diseases
  cyclo(4-9)GnRH, Lys(4)-Trp(6)-Glu(9)-
  dalarelin
  (des-Gly10,D-Ala6)-LHRH ethylamide
  detirelix
  fertirelin
  folligen
  ganirelix Has associated genes Has associated diseases
  GnRH (1-9)nonapeptide ethylamide, penicillamine-(tert-butyl)(6)-
  GnRH3-hinge-MVP
  GnRH, Ac(3,4)-dehydro-Pro(1)-4-fluoro-Phe(2)-Trp(3,6)-
  GnRH, Ac(4-Cl-Phe(1,2)-Trp(3)-Tyr(5)-Lys(6)-Ala(10))-
  GnRH, (Ac-dehydro-Pro(1)-4-Cl-Phe(2)-Trp(3,6))-N-(alpha)-MeLeu(7)-
  GnRH, acetyl(4-azidobenzoyl)-Lys(1)-4-chloro-Phe(2),Trp(3),Arg(6),Ala(10)-
  GnRH-hinge-MVP peptide
  GnRH-II, Ac-2-Nal(1)-4Cpa(2)-3Pal(3,6)-Leu(8)-Ala(10)-
  GnRH-III, acetyllysyl(4)-(daunorubicin-aminooxyacetyl)lysyl(8)-
  GnRH-II, Lys(6)-
  GnRH, Trp(6)-N-Me-Leu(7)-Pro(9)-N-Et-
  gonadorelin(6-D-Phe)
  Gonadorelin-like peptides
  gonadotropin releasing hormone associated peptide
  gonadotropin-releasing hormone-III
  Goserelin Has associated genes Has associated diseases
  histrelin
  lamprey GnRH-I
View node Leuprolide Has associated genes Has associated diseases
  L-GnRH-PE66 protein, chimeric
  LHRH (1-10)
  LHRH (1-5)
  LHRH (1-6)
  LHRH, 1,6-cyclo(Ac-Glu(1)-Phe(2)-Trp(3)-Lys(6))-
  LHRH (1-6), GlyNH2(6)-
  LHRH (1-9)
  LHRH, (1,9)-nonapeptide N-Et-ProNH(2)(9)-Gln(cyclohexyl)(6)-des-GlyNH(2)(10)-
  LHRH (2-10)
  LHRH (2-10), Trp(6)-
  LHRH, (3-(1H-pyrazol-3-yl))-Ala(2)-
  LHRH, 4-amino-Phe(6)-
  LHRH, 4-ClPhe(2)-Trp(3,6)-
  LHRH(5-10), Ac-
  LHRH, Ac-2-Nal(1)-4-Cl-Phe(2)-3-Pal(3)-Arg(5)-4-methoxybenzoyl-2-ABA(6)-Ala(10)-
  LHRH, Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Arg(Et2)(6)-Ala(10)-
  LHRH, Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Ser(Rha)(6)-AzGlyNH2(10)-
  LHRH, Ac-(4-Cl-Phe(1,2)-Trp(3)-Lys(6)-Ala(10))-
  LHRH, Ac-dehydro-Phe(1)-dehydro-4-Cl-Phe(2)-dehydro-Trp(3,6)-
  LHRH, Ac-dehydro-Pro(1)-4-Cl-Phe(2)-Trp(3,6)-
  LHRH, Ac-dehydro-Pro(1)-4-F-Phe(2)-Trp(3,6)-
  LHRH, Ac-delta(3)-Pro(1)-4-F-Phe(2)-Trp(3)-Lys(6)-
  LHRH, acetyl-2-(2-naphthyl)-Ala(1)-4-F-Phe(2)-Trp(3)-Arg(6)- Has associated genes Has associated diseases
  LHRH, Ac-Nal(1)-4-Cl-Phe(2)-Pal(3,6)-
  LHRH, Ac-Nal(1)-4-Cl-Phe(2)-Trp(3)-Arg(6)-Trp(7)-Ala(10)-
  LHRH, Ac-Nal(1)-Cpa(2)-Pal(3,6)-Arg(5)-Ala(10)-
  LHRH, Ac-Nal(1)-Cpa(2)-Trp(3)-Arg(6)-Ala(10)-
  LHRH, Ac-Nal-Ala(1)-4-Cl-Phe(2)-Ser(Rha)(6)-
  LHRH, Ala(6)-
  LHRH, Ala(6)-des-Gly(10)-
  LHRH, Ala(6)-Gly(10)-ethylamide- Has associated genes Has associated diseases
  LHRH, Ala(6)-N-Et-ProNH2(9)-iodo-
  LHRH, biotin-Lys(6)-
  LHRH, Boc-(Bzl)Ser(1)-des-His(2)-Trp(6)-
  LHRH, cLeu(7)-
  LHRH, cyclohexyl-Ala(7)-
  LHRH cysteamide, des-Arg-
  LHRH, des-His(2)-Ala(6)-
  LHRH, des-His(2)-Ala(6)-N-Et-ProNH2(9)-
  LHRH, des-His(2)-Leu(6)-
  LHRH, des-Tyr(5)-
  LHRH ethylamide, des-Gly(10)-Ala(6)-
  LHRH, Gln(1)-des-His(2)-Phe(6)-N-Et-ProNH2(9)-
  LHRH, Gln(8)-
  LHRH, Gly(10)-
  LHRH, His(5)-Arg(6)-Trp(7)-Tyr(8)-
  LHRH, His(5)-Trp(7)-Tyr(8)-
  LHRH, His(5)-Tyr(6)-
  LHRH, His(6)-N-Et-ProNH2(9)-
  LHRH, hydroxyprolyl(9)-
  LHRH, Leu(6)-
  LHRH, Leu(6)-des-Et-GlyNH2(10)- Has associated genes Has associated diseases
  LHRH, Leu(6)-Leu(N-alpha-Me)(7)-N-Et-ProNH2(9)-
  LHRH, Leu(6)-N-Et-GlyNH2(10)-
  LHRH, Lys(6)-
  LHRH, Lys(6)-EGS-Lys(6)-LHRH
  LHRH, Lys(6)-N-Et-GlyNH2(10)-
  LHRH, Lys(6)-N-Et-ProNH2(9)-
  LHRH, Lys(8)-
  LHRH, lysine(6)-doxorubicin
  LHRH, lysine(6)-glutaryl-2-(hydroxymethyl)anthraquinone
  LHRH, N-Ac(2)-Nal(1)-4-Cl-Phe(2)-3-Pal(3)-Arg(5)-5-(4-methoxyphenyl)-5-oxo-2-aminopentanoic acid(6)-Ala(10)-
  LHRH, N-Ac-2-Nal(1)-4-Cl-Phe(2)-3-Pal(3)-Arg(5)-Glu(6)-AlaNH2(10)-
  LHRH, N-Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Hci(6)-AlaNH2(10)-
  LHRH, N-Ac-2-naphthyl-Ala(1)-4-chloro-Phe(2)-pyridyl-Ala(3)-nicotinyl-Lys(5,6)-isopropyl-Lys(8)-AlaNH2(10)-
  LHRH, N-Ac-3-(2-dibenzofuranyl)-Ala(1)-
  LHRH, (N)-Ac-3(2-naphthyl)Ala(1)-(4-Cl-Phe)(2)-Trp(3)-Arg(6)-Phe(7)-AlaNH2(10)-
  LHRH, N-Ac-3(2-naphthyl)Ala(1)-Phe(2,3)-Arg(6)-Phe(7)-AlaNH2(10)-
  LHRH, N-Ac-(4-Cl-Phe)(1,2)-Phe(3)-Arg(6)-AlaNH2(10)-
  LHRH, N-Ac-(4-Cl-Phe)(1,2)-Trp(3)-Arg(6)-AlaNH2(10)-
  LHRH,(N)-Ac-(4-Cl-Phe)(1)-(4-Cl-Phe)(2)-Trp(3)-Phe(6)-AlaNH2(10)-
  LHRH, N-Ac-(4-F-Phe)(1)-(4-Cl-Phe)(2)-Trp(3,6)-AlaNH2(10)-
  LHRH, N-Ac-Ala(1)-(4-Cl-Phe)(2)-Trp(3,6)-
  LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- Has associated genes Has associated diseases
  LHRH, N-Ac-Gly(1)-(4-Cl-Phe)(2)-Trp(3,6)-
  LHRH, N-Ac-muramyl-Ala-iso-Glu-LysNH2-
  LHRH, N-Ac-Nal(1)-4-Cl-Phe(2)-Trp(3)-Cit(6)-AlaNH2(10)-
  LHRH, N-Ac-naphthyl(1)-(4-Cl-Phe)(2)-Trp(3)-Arg(6)-Ala(10)-
  LHRH, N-Ac-O-phenylTyr(1)-
  LHRH, N-Ac-Pro(1)-(4-Cl-Phe)(2)-(2-naphthyl-Ala)(3,6)-
  LHRH, N-Ac-Trp(1)-(4-Cl-Phe)(2)-Trp(3)-Arg(6)-Ala(10)-
  LHRH,(N)-Ac-Trp(1)-(4-Cl-Phe)(2)-Trp(3)-Phe(6)-AlaNH2(10)-
  LHRH, N-(Ac)-Trp(1)-(4-Cl-Phe)(2)-Trp(3)-Trp(6)-AlaNH2(10)-
  LHRH, N-epsilon-azidobenzoyl-Lys(6)-
  LHRH, N-Et-AlaNH2(6)-
  LHRH, pGlu(1)-4-Cl-Phe(2)-Trp(3,6)-
  LHRH, pGlu(1)-Phe(2)-Trp(3,6)-
  LHRH, pGlu(1)-Phe(2)-Trp(3)-Lys(6)-
  LHRH, pGlu(1)-Phe(2)-Trp(3)-Ser(4)-N-epsilon-azidobenzoyl-Lys(6)-
  LHRH, Phe(2)-Ala(6)-
  LHRH, Phe(2)-Leu(6)-
  LHRH, Phe(2)-N-epsilon-(2,4)-dinitrophenol-Lys(6)-
  LHRH, Phe(2)-Pro(3)-Phe(6)-
  LHRH, Phe(2)-Trp(3)-Phe(6)-
  LHRH, Phe(2)-Trp(6)-
  LHRH, Phe(5)-delta-Ala(6)-
  LHRH, Phe(5)-delta-Ala(6)-N-Et-ProNH2(9)-
  LHRH, Phe(6)-
  LHRH, Phe(7)-
  LHRH, Pro(1)-Phe(2)-Trp(3,6)-
  LHRH propylamide, Ala(6)-des-Gly(10)-
  LHRH, rhodamine
  LHRH, rhodamine-Lys(6)-
  LHRH, Ser(6)-
  LHRH, Trp(6)-des-GlyNH2(10)-
  LHRH, Trp(7)-
  LHRH, Trp(8)-
  lutrelin acetate
  (lysine(6)(1,3,8-trihydroxy-6-carboxyanthraquinone))GnRH
  meterelin
  MI 1544
  MI 1892
  MP 264
  MP 265
  N-Ac-(4-Cl-Phe)(1)-(4-Cl-Phe)(2)-Trp(3)-Lys(6)-AlaNH2(10)-LHRH
  N-acetyl-3-(3-quinolyl)alanyl-3-(4-chlorophenyl)alanyl-3-(3-pyridyl)alanyl-seryl-3-(4-pyrazinylcarbonylaminocyclohexyl)alanyl-N(epsilon)picolinoyllysyl-valyl-arginyl-prolyl-alaninamide
View node Nafarelin
  nymfon-orion
  Org 30850
  orntide acetate
  ovaprim
  ovurelin
  phLHRH (14-36), Ala(17)-
  porf-2 protein, rat
  progonadoliberin I
  pro-LHRH (14-69)OH
  P-X 1544
  P-X 1892
  pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl-alanyl-leucyl-arginyl-N-ethylprolinamide
  pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl methyl ester
  pyroglutamyl-histidyl-tryptophyl--seryl-tyrosyl-tryptophyl-leucyl-arginyl-prolyl-glycinamide
  relisorm L
  ricin A-GnRH conjugate
  RS 15378
  RS 18286
  salmon gonadotropin-releasing hormone precursor
  surfagon
View node Triptorelin Pamoate Has associated genes Has associated diseases
  Vaxstrate
  Wy 40905
  Wy 43657