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Chemical Lipids

These are exposure studies associated with the chemical and all of its children.

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1–50 of 88 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Vermeulen R, et al. (2004). Benzene and toluene exposures were determined in part by the degree of contact with glues, the benzene and toluene content of each glue, air movement and ventilation patterns. 1,1,1-trichloroethane | 2,2,4-trimethylpentane | 3-xylene | 4-xylene | Acetone | Benzene | chlorobenzene | ethyl acetate | ethylbenzene | ethylene dichloride | Heptanes | Hexanes | Methylene Chloride | methylethyl ketone | methyl isobutyl ketone | octane | pentane | Toluene Workers China air, indoor 1,1,1-trichloroethane | 2,2,4-trimethylpentane | 3-xylene | 4-xylene | Acetone | Benzene | chlorobenzene | ethyl acetate | ethylbenzene | ethylene dichloride | Heptanes | Hexanes | Methylene Chloride | methylethyl ketone | methyl isobutyl ketone | octane | pentane | Toluene Details
2. Svedberg UR, et al. (2004). High levels of hexanal and carbon monoxide were strongly associated with storage of wood pellets and may constitute an occupational and domestic health hazard. 1-Butanol | 2-heptenal | Acetone | Aldehydes | butyraldehyde | Carbon Monoxide | decanaldehyde | formic acid | heptanal | Methanol | n-hexanal | nonanal | pentanal | Terpenes | Toluene Study subjects Sweden air 1-Butanol | 2-heptenal | Acetone | Aldehydes | butyraldehyde | Carbon Monoxide | decanaldehyde | formic acid | heptanal | Methanol | n-hexanal | nonanal | pentanal | Terpenes | Toluene Details
3. Woodruff TJ, et al. (2011). National Health and Nutrition Examination Survey (NHANES) Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Pregnant females | Study subjects United States blood | serum | urine 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Details
4. Robledo CA, et al. (2015). Longitudinal Investigation of Fertility and the Environment Study (LIFE) Preconceptional maternal and paternal concentrations of several persistent organic pollutants were associated with statistically significant differences in birth size among offspring. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Fluorocarbons | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | Lindane | Mirex | N-ethyl perfluorooctane sulfonamido acetate | nonachlor | o,p'-DDT | oxychlordane | PBB 153 | PCB 180 | pentabromodiphenyl ether | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Infants or newborns | Mothers | Study subjects United States serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Fluorocarbons | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | Lindane | Mirex | N-ethyl perfluorooctane sulfonamido acetate | nonachlor | o,p'-DDT | oxychlordane | PBB 153 | PCB 180 | pentabromodiphenyl ether | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Details Prenatal Exposure Delayed Effects | developmental growth | head development
5. Braun JM, et al. (2014). Health Outcomes and Measures of the Environment (HOME) | National Health and Nutrition Examination Survey (NHANES) We used a semi-Bayesian hierarchical regression model to estimate associations between prenatal blood or urine concentrations of 52 suspected endocrine disrupting chemicals and autistic behaviors at 4 and 5 years of age in a prospective birth cohort of 175 mothers and their children. socioeconomic status | tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Children | Pregnant females | Study subjects United States serum | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Details Autism Spectrum Disorder
6. Robinson O, et al. (2015). INfancia y Medio Ambiente (INMA) Project In summary, the correlation analysis presented here of multiple environmental exposures among pregnant women provide a first picture of the structure of the exposome during the crucial in utero period. 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Pregnant females Spain air | blood, cord | colostrum | serum | urine | water 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Details
7. Makey CM, et al. (2016). Our findings suggest that polybrominated diphenyl ether exposure might decrease the binding of thyroxine (T4) to serum T4 binding proteins. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | perchlorate | thiocyanate | Thyroxine | tribromodiphenyl ether 28 Workers United States serum | urine 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | Iodine | Lipids | pentabrominated diphenyl ether 100 | perchlorate | thiocyanate | Thyroxine | tribromodiphenyl ether 28 | Triiodothyronine | TSHB Details thyroid hormone metabolic process
8. Béranger R, et al. (2016). PELAGIE Prenatal urine concentrations of two glycol ethers metabolites were associated with lower Wechsler Intelligence Scale for Children IV Verbal Comprehension Index scores and Developmental Neuropsychological Assessment Design Copying subscale scores, respectively, at age six. 2-(2-methoxyethoxy)ethanol | carbitol | Ethylene Glycols | n-butoxyacetic acid | phenoxyethanol Children | Pregnant females France urine carbitol | ethoxyacetic acid | methoxyacetic acid | n-butoxyacetic acid | phenoxyacetic acid Details cognition | visual learning
9. Lenters V, et al. (2016). In this study of mother-newborn pairs from Greenland, Poland, and Ukraine, prenatal exposure to a diethylhexyl phthalate metabolite (mono(2-ethyl-5-hydroxyhexyl) phthalate), perfluorooctanoic acid, and dichlorodiphenyldichloroethylene were independently associated with lower birth weight in term newborns. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Hydrocarbons, Chlorinated | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | phthalic acid Pregnant females Greenland|Poland|
Ukraine
serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | diisononyl phthalate | Hydrocarbons, Chlorinated | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono(carboxy-isooctyl)phthalate | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | phthalic acid Details Prenatal Exposure Delayed Effects
10. Hoppin JA, et al. (2017). Agricultural Health Study (AHS) We evaluated the association of currently used pesticides with allergic and non-allergic wheeze among male farmers, and our results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects. 2,4-Dichlorophenoxyacetic Acid | acetochlor | Atrazine | bentazone | Carbaryl | Chlorpyrifos | clomazone | clopyralid | cyfluthrin | Dicamba | Dimethoate | Disulfoton | fenoxaprop ethyl | fluazifop-butyl | glyphosate | Herbicides | imazaquin | Insecticides | Malathion | mesotrione | metolachlor | N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide | nicosulfuron | Permethrin | Petroleum | Picloram | Pyrethrins | Rodenticides | Simazine | triclopyr | Trifluralin | Warfarin Workers United States Details Respiratory Sounds | Rhinitis, Allergic
11. Louis GM, et al. (2015). Longitudinal Investigation of Fertility and the Environment Study (LIFE) We found that select perfluorinated chemicals at environmentally relevant concentrations were associated with differences in sperm head, morphology, and DNA characteristics, including differences indicative of higher and lower semen quality. 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Sulfonamides Study subjects United States serum 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Sulfonamides Details spermatogenesis
12. Fraser AJ, et al. (2013). Our investigation provides insight into concentrations of polyfluorinated compounds (PFCs) in the dust of offices, homes and vehicles in the United States and represents a novel attempt to assess contributions of different exposure media and microenvironments on PFC body burdens. 8-2 fluorotelomer alcohol | Fluorocarbons | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Workers United States dust 8-2 fluorotelomer alcohol | Fluorocarbons | hexadecafluoro-nonanoic acid | Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
13. Fraser AJ, et al. (2012). Fluorotelomer alcohol concentrations in office air significantly predict serum perfluorooctanoate concentrations in office workers. 8-2 fluorotelomer alcohol | Hydrocarbons, Fluorinated Workers United States air | serum 2-(N-ethylperfluorooctanesulfonamido)ethyl alcohol | 8-2 fluorotelomer alcohol | Hydrocarbons, Fluorinated | perfluorodecanoic acid | perfluorododecanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
14. Ferguson KK, et al. (2016). In the present mediation analysis we statistically demonstrate within a causal framework that the relationship between phthalate exposure and spontaneous preterm birth is mediated in part by phthalate-induced oxidative stress, which has not been elucidated clearly in human or animal studies previously. 8-epi-prostaglandin F2alpha | Diethylhexyl Phthalate | monobutyl phthalate Pregnant females United States urine Details Premature Birth | detection of oxidative stress
15. Luben TJ, et al. (2007). Healthy Men Study (HMS) The results of this study do not support an association between exposure to levels of disinfection by-products near or below regulatory limits and adverse sperm outcomes in humans. Acetates | Trihalomethanes | Water Pollutants, Chemical Study subjects United States Acetates | Trihalomethanes Details spermatogenesis
16. Lundström SL, et al. (2011). Several of the altered oxylipins have known or suspected bronchoprotective or anti-inflammatory effects, suggesting a possible reduced anti-inflammatory response in asthmatics following exposure to subway air. disease Air Pollutants Controls for disease:Asthma | Subjects with disease:Asthma Sweden lung 12,13-epoxy-9- keto-10-octadecenoic acid | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid | 13-hydroxy-9,11-octadecadienoic acid | 13-Hydroxy-octadecatrienoic acid | 13-oxo-9,11-octadecadienoic acid | 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid | 15-hydroxy-5,8,11,13-eicosatetraenoic acid | 15-hydroxyeicosatrienoic acid | 15-keto-5,8,11,13-eicosatetraenoic acid | 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid | 5,6-epoxy-8,11,14-eicosatrienoic acid | 5-hydroxy-6,8,11,14-eicosatetraenoic acid | 8,9-epoxyeicosatrienoic acid | 9,10,13-trihydroxyoctadec-11-enoic acid | 9,12,13-trihydroxy-10-octadecenoic acid | 9-hydroxy-10,12-octadecadienoic acid | 9-oxo-10,12-octadecadienoic acid | ALOX15 | Dinoprostone | Leukotriene B4 | PPARG | Prostaglandin D2 | PTGS1 | PTGS2 | Thromboxane B2 Details negative regulation of inflammatory response | oxylipin biosynthetic process
17. Logue JM, et al. (2012). The approach demonstrated in this study may be used to assess regional and national initiatives that affect indoor air quality at the population level. Cumulative health impacts from inhalation in U.S. residences of the indoor air pollutants assessed in this study are estimated at 400-1,100 disability-adjusted life years lost annually per 100,000 persons. Air Pollutants United States 1,1,1,2-tetrachloroethane | 1,1,2-trichloroethane | 1,3-butadiene | 2-butenal | 2-ethoxyethanol | 2-ethylhexanol | 2-phenylphenol | 2-xylene | 4-dichlorobenzene | Acetaldehyde | Acrolein | Acrylonitrile | Ammonia | Arsenic | Atrazine | Benzaldehydes | Benzene | Benzo(a)pyrene | benzyl chloride | Beryllium | bromodichloromethane | bromoform | Cadmium | Carbon Disulfide | Carbon Monoxide | Carbon Tetrachloride | chlorobenzene | chlorodibromomethane | Chloroform | Chromium | cumene | Cyclohexane | Diethylhexyl Phthalate | dioctyl adipate | Ethanol | ethylbenzene | Ethyl Chloride | Ethylene Dibromide | ethylene dichloride | Formaldehyde | hexachlorobutadiene | Manganese | Mercury | methyl cellosolve | Methyl Chloride | Methylene Chloride | methylethyl ketone | methyl isobutyl ketone | Methylmethacrylate | methyl tert-butyl ether | naphthalene | n-butoxyethanol | Nitrogen Dioxide | Ozone | Particulate Matter | Pentachlorophenol | Styrene | Sulfur Dioxide | Tetrachloroethylene | tetrahydrofuran | Toluene | Trichloroethylene | Vinyl Chloride | vinylidene chloride | Xylenes Details
18. Virtanen JK, et al. (2014). Kuopio Ischemic Heart Disease Risk Factor Study (KIHD) Serum long-chain omega-3 polyunsaturated fatty acids concentration, an objective biomarker for fish intake, was associated with long-term lower risk of type 2 diabetes. diet alpha-Linolenic Acid | Docosahexaenoic Acids | docosapentaenoic acid | Fatty Acids, Omega-3 | Mercury Study subjects Finland hair Mercury Details Diabetes Mellitus, Type 2
19. Kamel F, et al. (2014). Agricultural Health Study (AHS) | Farming and Movement Evaluation Study (FAME) Polyunsaturated fatty acid intake was consistently associated with lower Parkinson's disease (PD) risk, and dietary fats modified the association of PD risk with pesticide exposure. alpha-Linolenic Acid | Fatty Acids | Fatty Acids, Unsaturated | Paraquat | Rotenone Controls for disease:Parkinson Disease | Subjects with disease:Parkinson Disease | Workers United States Details Agricultural Workers' Diseases | Parkinson Disease
20. Nelson JW, et al. (2012). National Health and Nutrition Examination Survey (NHANES) In these data, family income with adjustment for family size was the strongest predictor of bisphenol A and polyfluoroalkyl chemicals levels among the different measures of socioeconomic position we studied. socioeconomic status bisphenol A Children | Study subjects United States serum | urine bisphenol A | perfluorohexanesulfonic acid | perfluoro-n-nonanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
21. Wright JM, et al. (2017). This is the first epidemiological study of birth defects and disinfection by-products (DBPs) to examine several individual cardiovascular defects, different exposure surrogate mixtures (sum of chloroform, bromoform, bromodichloromethane, and dibromochloromethane (THM4), brominated trihalomethanes, sum of monochloroacetic acid, dichloroacetic acid, trichloroacetic acid, monobromoacetic acid, and dibromoacetic acid (HAA5), sum of THM4 and HAA5, and various individual DBP species. sex bromoacetate | bromodichloromethane | bromoform | chloroacetic acid | chlorodibromomethane | Chloroform | dibromoacetic acid | Dichloroacetic Acid | Trichloroacetic Acid Fetuses | Pregnant females United States water, drinking Acetates | bromoacetate | bromodichloromethane | bromoform | chloroacetic acid | chlorodibromomethane | Chloroform | dibromoacetic acid | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Details Cardiovascular Abnormalities | Heart Septal Defects, Atrial | Heart Septal Defects, Ventricular | Pulmonary Valve Stenosis | Tetralogy of Fallot | Transposition of Great Vessels
22. Smith RB, et al. (2016). Born in Bradford (BiB) Study Our findings demonstrate associations between trihalomethane, but not haloacetic acid, exposure during pregnancy and reduced birth weight, but suggest this differs by ethnicity. race bromodichloroacetic acid | bromodichloromethane | chlorodibromomethane | Chloroform | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Pregnant females United Kingdom bromodichloroacetic acid | bromodichloromethane | chlorodibromomethane | Chloroform | Dichloroacetic Acid | Trichloroacetic Acid | Trihalomethanes Details
23. Kelishadi R, et al. (2013). Childhood and Adolescence Surveillance and Prevention of Adult Noncommunicable disease (CASPIAN) Cadmium levels were considerably high in adolescents with and without metabolic syndrome, and levels had positive but nonsignificant association with some cardiometabolic risk factors and liver enzymes; the associations did not reach statistical significance, perhaps due to high levels of cadmium in both groups or because of the young age of participants. Cadmium Children | Controls for disease:Metabolic Syndrome | Subjects with disease:Metabolic Syndrome Iran, Islamic Republic of blood | serum Blood Glucose | Cadmium | Cholesterol, HDL | Cholesterol, LDL | GOT1 | GPT | Triglycerides Details Metabolic Syndrome
24. Ellis JK, et al. (2012). This study shows evidence that metabolic profiling in an uncontrolled human population is capable of identifying intermediate biomarkers of response to cadmium at true environmental concentrations, paving the way for exposome research. Cadmium Study subjects United Kingdom urine 8-oxo-7-hydrodeoxyguanosine | beta-hydroxyisovaleric acid | Citric Acid | Creatine | Creatinine Details cellular response to oxidative stress
25. Tornhammar P, et al. (2014). Our objective was to assess the link between season of birth, neonatal 25-hydroxyvitamin D3, and adult cardiovascular disease; we report higher neonatal 25(OH)D3 associated with higher levels of cholesterol (in women), fasting insulin, and triglyceride, and with a higher risk of overweight at 35 years of age, but not with other adult cardiovascular disease risk factors. sex Calcifediol | Vitamin D Infants or newborns | Study subjects Sweden blood | serum Calcifediol | Cholesterol | Insulin | Triglycerides Details Obesity | Weight Gain | cholesterol homeostasis | regulation of insulin secretion | triglyceride homeostasis
26. Knobeloch L, et al. (2012). In an effort to assess residential exposure, we tested vacuum cleaner dust from 39 Wisconsin homes for several perflouroalkyl chemicals; the most commonly detected compounds were perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoic acid. Dust Study subjects United States dust, indoor perfluorobutyric acid | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Details
27. La Rocca C, et al. (2014). Our study indicates the relevance of the living environment when investigating the exposure to endocrine disrupters and the modulation of nuclear receptors (as a suitable biomarker of the effect) to assess the endocrine disrupters impact on reproductive health. Endocrine Disruptors Controls for disease:Infertility, Female | Subjects with disease:Infertility, Female Italy blood | leukocyte, mononuclear | serum AHR | AR | bisphenol A | ESR1 | ESR2 | mono-(2-ethylhexyl)phthalate | NR1I2 | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
28. de Cock M, et al. (2014). We assessed the association between prenatal exposure to various endocrine disrupting chemicals and child growth during the first year; exposure to phthalates and DDE was associated with body mass index as well as with head circumference during the first year after birth; these results should be interpreted with caution though, due to the limited sample size. Endocrine Disruptors Infants or newborns Netherlands blood, cord | milk, human 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | perfluorooctane sulfonic acid | perfluorooctanoic acid Details developmental growth | head development
29. Wattigney WA, et al. (2015). National Health and Nutrition Examination Survey (NHANES) We examined serum levels of persistent organic pollutants among four geographical U.S. regions (northeast, midwest, south, and west); differences in higher body burdens of exposure could be attributed to region-specific patterns of land use, industrial and agricultural chemical applications, and different levels of regulatory activity. Environmental Pollutants Study subjects United States serum 1,2,3,4,6,7,8-heptachlorodibenzodioxin | 1,2,3,6,7,8-hexachlorodibenzodioxin | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | tribromodiphenyl ether 28 Details
30. Berg V, et al. (2017). Northern Norway Mother-and-Child Contaminant Cohort Study (MISA) The present results suggest that background exposures to persistent organic pollutants can alter maternal thyroid homeostasis. Environmental Pollutants | Hexachlorobenzene | nonachlor | perfluorodecanoic acid | perfluorooctane sulfonic acid | perfluoroundecanoic acid | Pesticides | Polychlorinated Biphenyls Pregnant females Norway serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,4',5,5',6-heptachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | nonachlor | PCB 180 | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Thyroxine | Triiodothyronine | TSHB Details thyroid hormone generation | thyroid-stimulating hormone secretion
31. Lemire M, et al. (2015). Nunavik Health Survey The study objectives are to identify contemporary country food sources of methylmercury, selenium and long-chain omega-3 polyunsaturated fatty acids in Nunavik, particularly among childbearing-age women, taking into account regional differences in consumption profiles. Fatty Acids, Unsaturated | Methylmercury Compounds | Selenium Study subjects Canada blood | erythrocyte Fatty Acids, Unsaturated | Mercury | Methylmercury Compounds | Selenium Details
32. Schecter A, et al. (2012). Our results show that several Polyfluoroalkyl Compounds (PFCs) were detectable in children in Dallas, Texas, in 2009, including those born after changes in PFC manufacturing occurred. Fluorocarbons Children United States serum perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluoro-n-nonanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
33. Kataria A, et al. (2015). National Health and Nutrition Examination Survey (NHANES) Perfluoroalkyl acids are associated with a reduction in kidney function and increased uric acid levels in otherwise healthy adolescents. Fluorocarbons Children United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid | Uric Acid Details glomerular filtration
34. Fan H, et al. (2014). C8 Health Project (C8HP) Using 2005-2006 data from a large perfluorocarbon (PFC)-exposure population survey, we compared serum PFCs concentrations between Gilbert Syndrome (GS) and non GS clinical phenotypes, in a cross sectional design, adjusting for standard risk factors, including age, body mass index, smoking status, socioeconomic status and gender. sex Fluorocarbons | perfluorodecanoic acid | perfluorododecanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Controls for disease:Gilbert Disease | Subjects with disease:Gilbert Disease | Study subjects United States serum Fluorocarbons | perfluorodecanoic acid | perfluorododecanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Details Gilbert Disease
35. Lopez-Espinosa MJ, et al. (2016). C8 Health Project (C8HP) We found serum perfluoroalkyl substances concentrations to be associated with lower levels of sex hormones and IGF-1 in children aged 6-9 years. Fluorocarbons | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children United States serum Estradiol | IGF1 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Testosterone Details estradiol secretion | gene expression | testosterone secretion
36. Goudarzi H, et al. (2017). Sapporo Cohort, Hokkaido Study on Environment and Child Health Our results indicate that prenatal exposure to perfluorinated chemicals is significantly associated with glucocorticoid and dehydroepiandrosterone levels in cord blood. tobacco Fluorocarbons | perfluorooctane sulfonic acid | perfluorooctanoic acid Fetuses | Infants or newborns | Pregnant females Japan blood, cord | serum Androstenedione | Cortisone | Dehydroepiandrosterone | Hydrocortisone | perfluorooctane sulfonic acid | perfluorooctanoic acid Details cortisol secretion | dehydroepiandrosterone secretion
37. Shrestha S, et al. (2015). In the current study of older residents of the upper Hudson River communities, we detected positive associations between serum perfluorooctane sulfonate and free thyroxine and total thyroxine. age Halogenated Diphenyl Ethers | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls Study subjects United States serum Halogenated Diphenyl Ethers | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | Thyroxine | Triiodothyronine | TSHB Details thyroid hormone metabolic process
38. Webster GM, et al. (2016). National Health and Nutrition Examination Survey (NHANES) We found evidence of perfluoroalkyl acids-associated thyroid disruption in a subset of U.S. adults with high thyroid peroxidase antibody (a marker of autoimmune hypothyroidism) and low iodine status, who may represent a vulnerable subgroup. sex hexadecafluoro-nonanoic acid | Iodine | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum | urine hexadecafluoro-nonanoic acid | Iodine | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Thyrotropin | Thyroxine | Triiodothyronine Details thyroid hormone metabolic process
39. Grandjean P, et al. (2016). Diphtheria antibody concentrations decreased at elevated perfluorinated alkylate substance concentrations at ages 13 and 7 years, associations being statistically significant for perfluorodecanoate at age 7 and perfluorooctanoate at age 13, both suggesting a decrease by about 25% for each doubling of exposure. hexadecafluoro-nonanoic acid | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children Faroe Islands serum hexadecafluoro-nonanoic acid | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details IgG immunoglobulin complex, circulating
40. Mora AM, et al. (2016). Project Viva In this cohort, prenatal exposure to PFASs was associated with small increases in adiposity measurements in mid-childhood, but only among girls. sex hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children | Pregnant females United States plasma hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid Details Obesity | adipose tissue development
41. Calafat AM, et al. (2007). National Health and Nutrition Examination Survey (NHANES) In the general U.S. population in 2003-2004, perfluorooctane sulfonic acid, perfluorooctanoic acid, perfluorohexane sulfonic acid, and perfluorononanoic acid serum concentrations were measurable in each demographic population group studied. hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum hexadecafluoro-nonanoic acid | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
42. Lee WC, et al. (2017). Maternal-Infant Research on Environmental Chemicals (MIREC) Study We present an approach using factor analysis through principal component method and cluster analysis as an attempt to determine the pregnancy exposome; our results show the association between certain socio-demographic characteristics of the population of pregnant women and the presence of residual mixtures of common chemicals in their blood and urine. socioeconomic status Hydrocarbons, Fluorinated | Metals | Pesticides | Plasticizers | Polychlorinated Biphenyls Pregnant females Canada blood | plasma | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Arsenic | beta-hexachlorocyclohexane | bisphenol A | Cacodylic Acid | Cadmium | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | Lead | Manganese | Mercury | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | nonachlor | O,O-dimethyl phosphorothionate | oxychlordane | PCB 180 | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
43. Borg D, et al. (2013). The objective of this study was to for the first time perform a cumulative health risk assessment of the 17 perfluoroalkylated and polyfluoroalkylated substances measured in the Swedish population, individually and in combination, using the Hazard Index approach. Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Study subjects | Workers Sweden serum Hydrocarbons, Fluorinated | perfluorobutane | perfluorobutyric acid | perfluorodecanoic acid | perfluorododecanoic acid | perfluoroheptanoic acid | perfluorohexanesulfonic acid | perfluorohexanoic acid | perfluorononanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid Details Liver Diseases | immune response | mammary gland development | reproductive process
44. Weihe P, et al. (2008). To determine the prevalence and magnitude of exposure to polyfluoroalkyl compounds (PFCs) in the Faroe Islands, we measured the serum concentrations of 9 PFCs in two Faroese population groups. Hydrocarbons, Halogenated Children | Pregnant females Faroe Islands serum perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluoro-n-nonanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
45. Peters JL, et al. (2012). Normative Aging Study (NAS) Blood lead level may be related with cardiovascular disease in healthy older men through its association with tumor necrosis factor receptor-2 (TNFRSF1B); in addition, the magnitude of the association of blood lead level with TNFRSF1B level increased with age in the study population. genetics Lead Study subjects United States blood | patella | serum | tibia Cholesterol | Cholesterol, HDL | Cholesterol, LDL | CRP | ICAM1 | IL6 | Lead | TNFRSF1B | Triglycerides Details Cardiovascular Diseases
46. Kasperczyk S, et al. (2014). We examined the effects of N-acetylcysteine administration on the non-enzymatic defense systems (e.g., uric acid, albumin, bilirubin and alpha-tocopherol) in male workers exposed to lead, over a 12 week study period. Lead Workers Poland blood ALB | alpha-Tocopherol | Bilirubin | Lead | Lipid Peroxides | Uric Acid | zinc protoporphyrin Details
47. Khalil N, et al. (2016). National Health and Nutrition Examination Survey (NHANES) In a representative sample of the U.S. adult population, serum perfluoroalkyl substance (PFAS) concentrations were associated with lower bone mineral density, which varied according to the specific PFAS and bone site assessed. sex Lead | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States blood | serum Lead | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details Osteoporosis | bone mineralization
48. Harari F, et al. (2016). Our study suggests that lithium exposure through drinking water during pregnancy may impair the calcium homeostasis (particularly vitamin D): blood lithium was inversely associated with 25-hydroxyvitamin D3, positively associated with serum magnesium, and inversely associated with urinary calcium and magnesium. diet Lithium Pregnant females | Study subjects Argentina blood | plasma | serum | urine | water, drinking Arsenic | Boron | Calcifediol | Calcium | Cesium | Lithium | Magnesium | Phosphorus Details calcium ion homeostasis
49. Standl M, et al. (2011). German Infant Study on the Influence of Nutrition Intervention plus Environmental and Genetic Influences on Allergy (GINIplus) | Lifestyle-Related factors on the Immune System and the Development of Allergies in Childhood plus the influence of traffic emissions and genetics (LISAplus) The association between dietary intake of fatty acids (e.g., margarine) and allergic diseases (e.g., asthma) in children might be modulated by variants in the fatty acid desaturase gene cluster. diet | genetics Margarine Controls for disease:Asthma | Subjects with disease:Asthma | Children | Controls for disease:Eczema | Subjects with disease:Eczema | Subjects with gene influence:FADS1 | Subjects with gene influence:FADS2 | Controls for disease:Ige Responsiveness, Atopic | Subjects with disease:Ige Responsiveness, Atopic | Controls for disease:Rhinitis, Allergic, Seasonal | Subjects with disease:Rhinitis, Allergic, Seasonal Germany margarine Margarine Details Asthma
50. Olsen GW, et al. (2005). The present study was designed to assess the concentration trends of perfluorooctanesulfonate, perfluorooctanoate, and five other fluorochemicals in blood samples from individuals in the general population who resided near Washington County, Maryland, between 1974 and 1989. age N-ethyl perfluorooctane sulfonamido acetate | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Sulfonamides Study subjects United States plasma | serum N-ethyl perfluorooctane sulfonamido acetate | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Sulfonamides Details
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