Name | Lovastatin |
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CAS Type 1 Name | Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))- |
Equivalent Terms | 1 alpha-Isomer Lovastatin | 6 Methylcompactin | 6-Methylcompactin | alpha-Isomer Lovastatin, 1 | Lovastatin, 1 alpha Isomer | Lovastatin, 1 alpha-Isomer | Lovastatin, (1 alpha(S*))-Isomer | Mevacor | Mevinolin | MK803 | MK 803 | MK-803 | Monacolin K |
CAS Registry Number | 75330-75-5 |
Definition | A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. |
Structure | ![]() |
Top Interacting Genes |
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MeSH® ID | D008148 |
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