These are exposure studies associated with the chemical and all of its children.
Reference | Associated Study Title | Author's Summary | Study Factors | Stressor | Receptors | Country | Medium | Exposure Marker | Measurements | Outcome | |
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1. | Bergauff MA, et al. (2010). | These studies suggest that diet is a major factor in determining urinary levoglucosan levels and recent dietary history needs to be taken into account for future work involving levoglucosan as a biomarker of wood smoke exposure. | diet | 1,6- |
Study subjects | United States | urine | 1,6- |
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2. | Peng C, et al. (2016). | Normative Aging Study (NAS) | Among nondiabetics, short and medium-term exposures to PM2.5 particulate matter were associated with higher fasting blood glucose levels, and part of this association was mediated by ICAM1 gene promoter methylation. | Air Pollutants | Particulate Matter | Controls for disease:Diabetes Mellitus | United States | air, ambient | blood | blood buffy coat | Blood Glucose | ICAM1 | Particulate Matter | Details | glucose homeostasis | |
3. | Adetona O, et al. (2017). | In this study, we assessed occupational exposure to wildland fire smoke in wildland firefighters by measuring the urinary concentrations of hydroxylated metabolites of polycyclic aromatic hydrocarbons; our results suggest that hydroxylated PAHs (especially 4-hydroxyphenanthrene) may be useful biomarkers of wildland fire smoke exposure. | Air Pollutants, Occupational | Smoke | Workers | United States | air, ambient | urine | 1,6- |
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4. | Kelishadi R, et al. (2013). | Childhood and Adolescence Surveillance and Prevention of Adult Noncommunicable disease (CASPIAN) | Cadmium levels were considerably high in adolescents with and without metabolic syndrome, and levels had positive but nonsignificant association with some cardiometabolic risk factors and liver enzymes; the associations did not reach statistical significance, perhaps due to high levels of cadmium in both groups or because of the young age of participants. | Cadmium | Children | Controls for disease:Metabolic Syndrome | Subjects with disease:Metabolic Syndrome | Iran, Islamic Republic of | blood | serum | Blood Glucose | Cadmium | Cholesterol, HDL | Cholesterol, LDL | GOT1 | GPT | Triglycerides | Details | Metabolic Syndrome | |
5. | He K, et al. (2013). | Coronary Artery Risk Development in Young Adults (CARDIA) Study | Our results provide longitudinal human data suggesting that people with high mercury exposure in young adulthood may have elevated risk of diabetes later in life. | Mercury | Study subjects | United States | nail, toe | plasma | Blood Glucose | INS | Mercury | Details | Diabetes Mellitus | regulation of insulin secretion involved in cellular response to glucose stimulus | |
6. | Migliaccio CT, et al. (2009). | These results demonstrate that levoglucosan in the lungs is detectable in the urine of both mice and humans and that it is a good candidate as a biomarker of exposure to biomass smoke. | Particulate Matter | Tobacco Smoke Pollution | Children | United States | air | urine | 1,6- |
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