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Chemical Mycophenolic Acid

Name Mycophenolic Acid
CAS Type 1 Name -Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
Equivalent Term Acid, Mycophenolic
CAS Registry Number 24280-93-1
Definition An antibiotic substance derived from Penicillium stoloniferum, and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1301)
Structure Mycophenolic Acid
Top Interacting
Genes
MeSH® ID D009173
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Carboxylic Acids Has associated genes Has associated diseases Has associated exposure references Acids, Acyclic Has associated genes Has associated diseases Has associated exposure references Caproates Has associated genes Has associated diseases Has associated exposure references Mycophenolic Acid Has associated genes Has associated diseases
2. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Mycophenolic Acid Has associated genes Has associated diseases

Top ↑ Descendants

Mycophenolic Acid Has associated genes Has associated diseases
  1,3-dipalmitoyl-2-mycophenoloyl glycerol
  2,3,5-trihydroxy-5-(propylcarbamoyl)cyclohexyl 6-(4-ethoxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate
  6-((2E,6E)-3,7,11-trimethyldedoca-2,6,10-trienyl)-7-hydroxy-5-methoxy-4-methylphtanlan-1-one
  6-((2E,6E)-3,7-dimethyldeca-2,6-dienyl)-7-hydroxy-5-methoxy-4-methylphtanlan-1-one
  beta-methylene-mycophenolic adenine dinucleotide
  C2-mycophenolic adenine dinucleotide
  C4-mycophenolic adenine dinucleotide
  C6-mycophenolic adenine dinucleotide
  carbamoyl mycophenolic acid ethyl ester
  dextran T70-mycophenolic acid conjugate
  ethyl O-(N-(4-carboxyphenyl)carbamoyl)mycophenolate
  euparvic acid
  F01 1358A
  F01 1358B
  F13459
  mycophenolate mofetil Has associated genes Has associated diseases
  mycophenolic acid glucuronide Has associated genes Has associated diseases
  mycophenolic adenine dinucleotide
  penicacid A
  penicacid B
  penicacid C