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Chemical Naltrexone

Name Naltrexone
CAS Type 1 Name Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-
Equivalent Terms Antaxone | Bristol Myers Squibb Brand of Naltrexone Hydrochloride | Bristol-Myers Squibb Brand of Naltrexone Hydrochloride | Celupan | Du Pont Brand of Naltrexone Hydrochloride | EN1639A | EN 1639A | EN-1639A | Hydrochloride, Naltrexone | Lacer Brand of Naltrexone Hydrochloride | Lamepro Brand of Naltrexone Hydrochloride | Nalorex | Naltrexone Hydrochloride | Nemexin | Orphan Brand of Naltrexone Hydrochloride | Pharmazam Brand of Naltrexone Hydrochloride | ReVia | Schering Plough Brand of Naltrexone Hydrochloride | Schering-Plough Brand of Naltrexone Hydrochloride | Trexan | United Drug Brand of Naltrexone Hydrochloride
CAS Registry Number 16590-41-3
Definition Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Structure Naltrexone
Top Interacting
Genes
MeSH® ID D009271
External Links

Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Alkaloids Has associated genes Has associated diseases Has associated exposure references Opiate Alkaloids Has associated genes Has associated diseases Morphinans Has associated genes Has associated diseases Naloxone Has associated genes Has associated diseases Naltrexone Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds with 4 or More Rings Has associated genes Has associated diseases Has associated exposure references Morphinans Has associated genes Has associated diseases Naloxone Has associated genes Has associated diseases Naltrexone Has associated genes Has associated diseases
3. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Bridged-Ring Has associated genes Has associated diseases Morphinans Has associated genes Has associated diseases Naloxone Has associated genes Has associated diseases Naltrexone Has associated genes Has associated diseases
4. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Polycyclic Hydrocarbons, Aromatic Has associated genes Has associated diseases Has associated exposure references Phenanthrenes Has associated genes Has associated diseases Has associated exposure references Morphinans Has associated genes Has associated diseases Naloxone Has associated genes Has associated diseases Naltrexone Has associated genes Has associated diseases

Top ↑ Descendants

Naltrexone Has associated genes Has associated diseases
  10-ketonaltrexone
  14-chloroacetylnaltrexone
  17,17'-bis(cyclopropylmethyl)-6,6',7,7'-tetrahydro-4,5-4',5'-diepoxy-6,6'-(benzylimino)(7,7'-bimorphinan)-3,3',14,14'-tetrol Has associated genes Has associated diseases
  17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-((2'-indolyl)acetamido)morphinan
  17-cyclopropylmethyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one-7-spiro-2'-indan
  17-(cyclopropylmethyl)-4,5-epoxy-3,4-dihydroxy-6-((phthalaldehydecarboxamido)acetamido)morphinan
  17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5',6'-dihydro-3-methoxy-4'H-pyrrolo(3,2,1-ij)quinolino(2',1'-6,7)morphinan-14-ol
  17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-8'-fluoro-5',6'-dihydro-4'H-pyrrolo(3,2,1-ij)quinolino(2',1'-6,7)morphinan-3,14-diol
  17-cyclopropylmethyl-6,7-didehydro-4-hydroxy-3-methoxy-6,7-2',3'-indolomorphinan
  17-(cyclopropylmethyl)-7-benzyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one
  2-hydroxy-3-methoxy-6 beta-naltrexol
  3,3'-di-(N-cyclopropylmethyl-4,5-epoxy-14-hydroxymorphinan-6-one-3-yl)carbonate
  3,6,14-trihydroxy-6-(2-carboxyallyl)-17-(cyclopropylmethyl)morphinan gamma-lactone 4,5-epoxide
  3-acetyl-6-deoxy-6-fluoronaltrexone
  3-carboxamido-4-hydroxynaltrexone
  3-methoxynaltrexone
  5'-acetamidinoethylnaltrindole
  6-(2-phenylethyl)oximino naltrexone
  6-(3-phenylpropyl)oximino naltrexone
  6,6'-(ethylenebis(oxyethyleneimino))bis(17-cyclopropylmethyl)-4,5-epoxymorphinan-3,14-diol
  6 beta-hydroxynaltrexone Has associated genes Has associated diseases
  6-bromoacetamido-6-desoxynaltrexone
  6-deoxy-6-fluoronaltrexone
  6'-guanidinonaltrindole Has associated genes Has associated diseases
  6-thioglycolamido-6-desoxynaltrexone
  7-(2-methoxybenzylidene)naltrexone
  7-(4-methylbenzylidene)naltrexone
  7-(5',6'-benzo-2'-spiroindanyl)naltrexone
  7-benzylidenenaltrexone Has associated genes Has associated diseases
  beta-funaltrexamine Has associated genes Has associated diseases
  beta-naltrexamine Has associated genes Has associated diseases
  beta-naltrexyl-6-ethylenediamine
  binaltorphimine
  bupropion hydrochloride, naltrexone hydrochoride drug combination
  chlornaltrexamine Has associated genes Has associated diseases
  CNGN-TI compound
  HS 378
  iodobenzoylnaltrexamide
  KDAN 18
  KDN 21
  KMN-21 compound
  KNT 93
  methylnaltrexone Has associated genes Has associated diseases
  morphine, naltrexone combination Has associated diseases
  N1'-fluoroethyl-(14-formylamino)naltrindole
  N1'-fluoroethyl-naltrindole
  nalmafene 3-O-diglucuronide
  nalmefene Has associated genes Has associated diseases
  naltrexamine, N(beta)-(Leu-Arg-Arg-Leu-Phe)-
  naltrexazone
  naltrexonazine
  naltrexone 3-glucuronide
  naltrexone-3-O-(2'-ethylbutyrate)
  naltrexone-3-O-valerate
  naltrexone-3-salicylate
  naltrexone-estrone azine
  naltrexone phenyl oxime
  naltrindole Has associated genes Has associated diseases
  naltrindole 5'-isothiocyanate
  naltrindole benzofuran Has associated genes Has associated diseases
  NAP naltrexamine
  N-benzylnaltrindole
  N-methylfunaltrexamine
  N-naphthoyl-beta-naltrexamine
  norbinaltorphimine Has associated genes Has associated diseases
  NTI compound
  oxycodone naltrexone combination
  oxymorphone-3-methoxynaltrexonazine
  oxymorphone-naltrexonazine
  Oxytrex Has associated diseases
  pregnenolone-naltrexone azine
  SDM 25N
  SG-II-49 compound
  WYE-120318