Skip navigation

Chemical Naphthols

These are exposure studies associated with the chemical and all of its children.

Send correction
1–24 of 24 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Aquilina NJ, et al. (2010). Measurement and Modelling of Air Toxic Concentrations for Health Effect Studies Project (MATCH) The objective of this study was to analyse environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbon (PAH) metabolites in urine samples of non-occupationally exposed non-smoker adult subjects and to establish relationships between airborne exposures and urinary concentrations in order to assess the suitability of the studied metabolites as biomarkers of PAH and ETS, study the use of 3-ethenypyridine as ETS tracer, and link ETS scenarios with exposures to carcinogenic PAH and volatile organic compounds. tobacco 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 3-vinylpyridine | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | coronene | fluoranthene | fluorene | hydroxycotinine | indeno(1,2,3-cd)pyrene | naphthalene | Nicotine | phenanthrene | Polycyclic Aromatic Hydrocarbons | pyrene Study subjects United Kingdom urine 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 3-vinylpyridine | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | coronene | fluoranthene | fluorene | hydroxycotinine | indeno(1,2,3-cd)pyrene | naphthalene | Nicotine | phenanthrene | Polycyclic Aromatic Hydrocarbons | pyrene Details
2. Goniewicz ML, et al. (2018). Population Assessment of Tobacco and Health (PATH) Study These findings provide evidence that using combusted tobacco cigarettes alone or in combination with e-cigarettes is associated with higher concentrations of potentially harmful tobacco constituents in comparison with using e-cigarettes alone. tobacco 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-butenal | 2-hydroxyfluorene | 2-naphthol | 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol | Acrolein | Acrylamide | Acrylonitrile | Anabasine | anatabine | Arsenic | Benzene | Beryllium | Cadmium | Carbon Disulfide | Cobalt | Cotinine | cotinine-N-oxide | Dimethylformamide | ethylbenzene | Ethylene Oxide | Fluorenes | hydroxycotinine | Isocyanates | isoprene | Lead | mandelic acid | Manganese | nicotine 1-N-oxide | Nicotine | N'-nitrosoanabasine | N'-nitrosoanatabine | N'-nitrosonornicotine | norcotinine | nornicotine | Phenanthrenes | propylene oxide | Strontium | Styrene | Thallium | Toluene | Uranium | Vinyl Chloride | Xylenes Study subjects United States urine 1,3-butadiene | 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-butenal | 2-hydroxyfluorene | 2-methylhippuric acid | 2-naphthol | 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol | Acrolein | Acrylamide | Acrylonitrile | Anabasine | anatabine | Arsenic | Benzene | Beryllium | Cadmium | Carbon Disulfide | Cobalt | Cotinine | cotinine-N-oxide | Dimethylformamide | Fluorenes | Hippurates | hydroxycotinine | isoprene | Lead | mandelic acid | Manganese | N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine | N-acetyl-S-(2-cyanoethyl)cysteine | N-acetyl-S-(2-hydroxyethyl)cysteine | nicotine 1-N-oxide | Nicotine | N'-nitrosoanabasine | N'-nitrosoanatabine | N'-nitrosonornicotine | norcotinine | nornicotine | Phenanthrenes | phenylglyoxylic acid | propylene oxide | S-(3-hydroxypropyl)cysteine N-acetate | S-benzyl-N-acetyl-L-cysteine | Strontium | Thallium | Uranium Details
3. Goniewicz ML, et al. (2017). This study showed for the first time that after switching from tobacco to e-cigarettes, nicotine exposure remains unchanged, while exposure to selected carcinogens and toxicants is substantially reduced. tobacco 1,3-butadiene | 2-butenal | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Acrolein | Acrylamide | Acrylonitrile | Benzene | Carbon Monoxide | Ethylene Oxide | fluorene | naphthalene | Nicotine | phenanthrene | propylene oxide | pyrene Study subjects Poland urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 3-hydroxy-1-methylpropylmercapturic acid | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol | Acetylcysteine | Carbon Monoxide | Cotinine | cotinine-N-oxide | fluorene | hydroxycotinine | N-acetyl-S-(2-hydroxyethyl)cysteine | nicotine 1-N-oxide | Nicotine | norcotinine | nornicotine | phenanthrene | S-phenyl-N-acetylcysteine Details
4. Li J, et al. (2018). Coke-oven Workers (COW) Cohort | Shiyan (SY) Cohort | Wuhan-Zhuhai (WHZH) Cohort Our findings suggest that exposure to polycyclic aromatic hydrocarbons may be associated with an adverse impact on human aging and epigenetic alterations in Chinese populations. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Study subjects China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details aging | DNA methylation
5. Deng Q, et al. (2014). Coke-oven Workers (COW) Cohort We identified five potentially polycyclic aromatic hydrocarbon (PAH)-associated miRNAs in plasma, and the same miRNAs were associated with a marker of chromosome damage in coke oven workers, suggesting that miRNAs might be a novel mechanism mediating the effects of PAH exposure on chromosome damage. alcohol drinking 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Workers China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details miRNA metabolic process
6. Yang B, et al. (2016). Our results indicated polycyclic aromatic hydrocarbons exposure was associated with plasma cytokines, and higher cytokines were associated with decreased heart rate variability, but additional human and potential mechanistic studies are needed. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Workers China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | ALCAM | BDNF | CRP | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details Cardiovascular Diseases | gene expression
7. Li Z, et al. (2012). This study aimed to investigate the excretion half-life of 1-hydroxypyrene (1-PYR), the most used biomarker for polycyclic aromatic hydrocarbon (PAH) exposure, and 9 other mono-hydroxylated metabolites following a dietary exposure in 9 non-smoking volunteers with no occupational exposure to PAHs. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Fluorenes | Phenanthrenes Study subjects United States urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Fluorenes | Phenanthrenes Details
8. Barraza-Villarreal A, et al. (2014). Biomarkers of polycyclic aromatic hydrocarbons exposure were inversely associated with lung function and decrease of pH of exhaled breath condensate as a marker of airway inflammation in Mexican schoolchildren. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Fluorenes | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Children Mexico urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Fluorenes | Phenanthrenes Details respiratory system process
9. Zhou Y, et al. (2016). Wuhan-Zhuhai (WHZH) Cohort Total and specific urinary polycyclic aromatic hydrocarbons metabolites were associated with lung function reduction in a general Chinese population. 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Study subjects China urine Polycyclic Aromatic Hydrocarbons Details respiratory system process
10. Woodruff TJ, et al. (2011). National Health and Nutrition Examination Survey (NHANES) Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Pregnant females | Study subjects United States blood | serum | urine 1-hydroxypyrene | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-naphthol | 4-dichlorobenzene | Benzene | bisphenol A | Cadmium | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | fluoren-9-ol | Hexachlorobenzene | Lead | Mercury | methyl tert-butyl ether | mono-benzyl phthalate | monobutyl phthalate | mono-isobutyl phthalate | O,O-dimethyl phosphorodithioate | O,O-dimethyl phosphorothionate | oxybenzone | PCB 180 | perchlorate | perfluorooctane sulfonic acid | perfluorooctanoic acid | thiophosphoric acid | Toluene | Triclosan Details
11. Bradman A, et al. (2003). As a first step in validating this (amniotic fluid) exposure biomarker, we collected 100 amniotic fluid samples slated for disposal and evaluated analytical methods to measure organophosphate and carbamate pesticides and metabolites, synthetic pyrethroid metabolites, herbicides, and chlorinated phenolic compounds. 1-naphthol | 2,5-dichlorophenol | 2-naphthol | 2-phenylphenol | Carbofuran | diethyl phosphate | dimethyl phosphate | O,O-dimethyl phosphorothionate | Pentachlorophenol Mothers United States amniotic fluid 1-naphthol | 2,5-dichlorophenol | 2-naphthol | 2-phenylphenol | Carbofuran | diethyl phosphate | dimethyl phosphate | O,O-dimethyl phosphorothionate | Pentachlorophenol Details
12. Meeker JD, et al. (2004). In the present study we found associations between urinary metabolites of contemporary-use insecticides and decreased sperm concentration and motility in humans. 1-naphthol | 3,5,6-trichloro-2-pyridinol | Insecticides Subjects with disease:Infertility, Male United States semen | urine 1-naphthol | 3,5,6-trichloro-2-pyridinol Details Infertility, Male | spermatogenesis | sperm motility
13. Adetona O, et al. (2017). In this study, we assessed occupational exposure to wildland fire smoke in wildland firefighters by measuring the urinary concentrations of hydroxylated metabolites of polycyclic aromatic hydrocarbons; our results suggest that hydroxylated PAHs (especially 4-hydroxyphenanthrene) may be useful biomarkers of wildland fire smoke exposure. Air Pollutants, Occupational | Smoke Workers United States air, ambient | urine 1,6-anhydro-beta-glucopyranose | 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | Carbon Monoxide | Particulate Matter | Polycyclic Aromatic Hydrocarbons Details
14. Kieszak SM, et al. (2002). National Health and Nutrition Examination Survey (NHANES) | Priority Toxicant Reference Range Study (PTRRS) The main objective of our study was to determine whether we could use data from the Third National Health and Nutrition Examination Survey (NHANES III) to detect a relation between self-reported food consumption (particularly consumption of fruits, vegetables, and bread products) and urinary levels of pesticides or their metabolites in a population of 978 adults living in the US. diet Carbaryl | Chlorpyrifos | naphthalene | Pentachlorophenol | Pesticides Study subjects United States urine 1-naphthol | 2-isopropoxyphenol | 3,5,6-trichloro-2-pyridinol | 4-nitrophenol | Pentachlorophenol Details
15. Chao YC, et al. (2006). We conclude that dermal exposure to jet propellant type-8 significantly contributes to the systemic dose and affects the levels of urinary naphthalene metabolites. JP8 aviation fuel Military personnel United States air, breath | skin | urine 1-naphthol | 2-naphthol | naphthalene Details
16. Smith KW, et al. (2012). Overall, we found that the a priori assigned exposure group and breathing-zone naphthalene were significant predictors of post-shift levels of both urinary biomarkers and that there may be accumulation of 1-naphthol over the work week. Job-related activities such as entering the fuel tank and wearing gloves during the work-shift were found to influence post-shift urinary biomarker levels among participants in the high exposure group. JP8 aviation fuel | naphthalene Military personnel United States urine 1-naphthol | 2-naphthol Details
17. Sul D, et al. (2012). Korea National Survey for Environmental Pollutants in the Human Body This study is the first nationwide survey of exposure to polycyclic aromatic hydrocarbons and nicotine in Korea and provides a background reference range for exposure to polycyclic aromatic hydrocarbons and nicotine in the Korean general population. Nicotine | Polycyclic Aromatic Hydrocarbons Study subjects Korea, Republic of urine 1-hydroxypyrene | 2-naphthol | Cotinine Details
18. Castorina R, et al. (2010). Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) | National Health and Nutrition Examination Survey (NHANES) Our findings indicate that pregnant women in the Salinas Valley are chronically exposed to several current-use organophosphorus and organochlorine pesticides and chlorinated phenols, with additional intermittent exposures to other pesticides. Findings suggest that the CHAMACOS cohort has an additional burden of precursor pesticide exposure compared with the national sample, possibly from living and/or working in an agricultural area. Pesticides Pregnant females United States urine 1-naphthol | 2,4,5-trichlorophenol | 2,4,6-trichlorophenol | 2,4-dichlorophenol | 2,4-Dichlorophenoxyacetic Acid | 2,5-dichlorophenol | 2-naphthol | 2-phenylphenol | 3,5,6-trichloro-2-pyridinol | 3-phenoxybenzoic acid | 4-nitrophenol | acephate | DEET | Dimethoate | Ethylenethiourea | Pentachlorophenol Details
19. Alshaarawy O, et al. (2016). National Health and Nutrition Examination Survey (NHANES) A modest association between levels of polycyclic aromatic hydrocarbon urinary biomarkers and cardiovascular disease was detected in US adults. Polycyclic Aromatic Hydrocarbons Study subjects United States urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol Details Cardiovascular Diseases
20. Nethery E, et al. (2012). Study to identify polycyclic aromatic hydrocarbons in the urine of pregnant women as biomarkers of exposure in air Polycyclic Aromatic Hydrocarbons Pregnant females Canada urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Nitric Oxide | Nitrogen Dioxide | Particulate Matter Details
21. Yoon HS, et al. (2012). Using the urinary biomarkers 1-hydroxypyrene-glucuronide (1-OHPG), 2-naphthol, and malondialdehyde (MDA), we evaluated seasonal and regional variations in polycyclic aromatic hydrocarbon (PAH) exposure and oxidative stress among Korean adults and children. Polycyclic Aromatic Hydrocarbons | Tobacco Smoke Pollution Children | Study subjects Korea, Republic of urine 1-hydroxypyrene-glucuronide | 2-naphthol | Malondialdehyde Details
22. St Helen G, et al. (2012). Concentrations of polycyclic aromatic hydrocarbon (PAH) metabolites in smokers and nonsmokers, their elimination kinetics in smokers, and the associations between nicotine intake, tobacco biomarkers, and PAH metabolites in smokers were investigated. Polycyclic Aromatic Hydrocarbons | Tobacco Smoke Pollution Study subjects Poland|United States urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol | Fluorenes | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details
23. Zhu X, et al. (2016). Wuhan-Zhuhai (WHZH) Cohort We identified DNA methylation markers associated with smoking in a Chinese population, including some markers that were also correlated with gene expression. tobacco Tobacco Smoke Pollution Study subjects China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Polycyclic Aromatic Hydrocarbons Details DNA methylation on cytosine within a CG sequence
24. Zhang X, et al. (2015). Our results show that occupational exposure to diesel engine exhaust can induce increases in micronucleus, nucleoplasmic bridge, and nuclear bud frequencies in peripheral blood lymphocytes. Vehicle Emissions Workers China air, indoor | urine 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 9-phenanthrol | acenaphthene | acenaphthylene | anthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | Carbon | chrysene | fluoranthene | fluorene | indeno(1,2,3-cd)pyrene | naphthalene | Particulate Matter | phenanthrene | Polycyclic Aromatic Hydrocarbons Details Chromosome Aberrations | Micronuclei, Chromosome-Defective | micronucleus organization
1–24 of 24 results.