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Chemical Nicotinic Acids

1–50 of 634 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 2-(7-(3,4-dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide positive regulation of retinoic acid receptor signaling pathway Vitamin A 2-(7-(3,4-dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide inhibits the reaction [Vitamin A results in increased positive regulation of retinoic acid receptor signaling pathway] 1: Mus musculus Embryo, Mammalian | Fibroblasts | Cell Line   1
2. 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide negative regulation of prostaglandin biosynthetic process 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide results in increased negative regulation of prostaglandin biosynthetic process 1: Mus musculus Sertoli Cells | Cell Line   1
3. 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide cell proliferation 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide results in decreased cell proliferation 1: Homo sapiens Breast | Cell Line, Tumor   1
4. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide mitotic cell cycle arrest 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased mitotic cell cycle arrest 1: Homo sapiens Prostate | Cell Line, Tumor   1
5. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide apoptotic process 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased apoptotic process 1: Homo sapiens Prostate | Cell Line, Tumor
7 genes: AKT1 | BAD | CASP3 | CASP8 | CASP9 | CDK1 | PARP1
1
6. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide regulation of mitochondrial membrane potential 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog affects regulation of mitochondrial membrane potential 1: Homo sapiens Prostate | Cell Line, Tumor   1
7. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide release of cytochrome c from mitochondria 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased release of cytochrome c from mitochondria 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: BAD 1
8. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide cell proliferation Dihydrotestosterone 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog inhibits the reaction [Dihydrotestosterone results in increased cell proliferation] 1: Homo sapiens Prostate | Cell Line, Tumor
4 genes: AKT1 | AR | BAD | CDK1
1
9. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens HCT116 Cells
3 genes: AKT1 | BCL2L1 | CDC25C
1
10. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells
3 genes: AKT1 | BCL2L1 | CDC25C
1
11. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: AKT1 | BCL2L1 | CDC25C
1
12. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens HeLa Cells
3 genes: AKT1 | BCL2L1 | CDC25C
1
13. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens Ovary | Cell Line, Tumor
3 genes: AKT1 | BCL2L1 | CDC25C
1
14. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor
3 genes: AKT1 | BCL2L1 | CDC25C
1
15. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic cell cycle arrest 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased mitotic cell cycle arrest 1: Homo sapiens HCT116 Cells   1
16. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic cell cycle arrest 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased mitotic cell cycle arrest 1: Homo sapiens Ovary | Cell Line, Tumor   1
17. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid tubulin complex assembly 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased tubulin complex assembly     1
18. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid regulation of microtubule polymerization 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects regulation of microtubule polymerization 1: Homo sapiens HCT116 Cells   1
19. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic spindle assembly 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased mitotic spindle assembly 1: Homo sapiens HCT116 Cells   1
20. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic spindle assembly 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects mitotic spindle assembly 1: Homo sapiens Ovary | Cell Line, Tumor   1
21. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid chromosome localization 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects chromosome localization 1: Homo sapiens HCT116 Cells   1
22. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid chromosome localization 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects chromosome localization 1: Homo sapiens Ovary | Cell Line, Tumor   1
23. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid apoptotic process 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased apoptotic process 1: Homo sapiens HCT116 Cells
7 genes: AKT1 | BCL2L1 | BID | CASP3 | CASP7 | MCL1 | PARP1
1
24. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid apoptotic process 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased apoptotic process 1: Homo sapiens Ovary | Cell Line, Tumor
7 genes: AKT1 | BCL2L1 | BID | CASP3 | CASP7 | MCL1 | PARP1
1
25. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid activation of cysteine-type endopeptidase activity involved in apoptotic process 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects activation of cysteine-type endopeptidase activity involved in apoptotic process 1: Homo sapiens Dermis | Microvessels | Endothelial Cells | Cell Line
2 genes: BID | CASP3
1
26. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid activation of cysteine-type endopeptidase activity involved in apoptotic process 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased activation of cysteine-type endopeptidase activity involved in apoptotic process 1: Homo sapiens HCT116 Cells
2 genes: BID | CASP3
1
27. 6-Aminonicotinamide positive regulation of protein import into nucleus 6-Aminonicotinamide results in decreased positive regulation of protein import into nucleus 1: Homo sapiens Pluripotent Stem Cells | Cells, Cultured 1 gene: TGFB1 1
28. 6-Aminonicotinamide positive regulation of cell death 6-Aminonicotinamide results in increased positive regulation of cell death 1: Mus musculus Embryonic Stem Cells | Cells, Cultured
2 genes: IL1B | MT3
1
29. 6-Aminonicotinamide positive regulation of stem cell differentiation 6-Aminonicotinamide results in decreased positive regulation of stem cell differentiation 1: Mus musculus Embryonic Stem Cells | Cells, Cultured 1 gene: GSK3B 1
30. 6-Aminonicotinamide positive regulation of cell death 6-Aminonicotinamide results in increased positive regulation of cell death 1: Homo sapiens Retina | Cell Line, Tumor
2 genes: IL1B | MT3
1
31. 6-Aminonicotinamide positive regulation of cell death Fenretinide 6-Aminonicotinamide promotes the reaction [Fenretinide results in increased positive regulation of cell death] 1: Homo sapiens Retina | Cell Line, Tumor
2 genes: IL1B | MT3
1
32. 6-Aminonicotinamide cell death Paraquat | SNCA 6-Aminonicotinamide inhibits the reaction [SNCA protein promotes the reaction [Paraquat results in increased cell death]] 1: Homo sapiens Dopaminergic Neurons | Cell Line, Transformed 1 gene: HMOX1 1
33. 6-Aminonicotinamide cell death Paraquat | SNCA 6-Aminonicotinamide inhibits the reaction [SNCA protein mutant form promotes the reaction [Paraquat results in increased cell death]] 1: Homo sapiens Dopaminergic Neurons | Cell Line, Transformed 1 gene: HMOX1 1
34. arecaidine esters regulation of blood pressure arecaidine esters analog results in increased regulation of blood pressure 1: Rattus norvegicus Hippocampus   1
35. Arecoline regulation of blood pressure Arecoline results in increased regulation of blood pressure 1: Rattus norvegicus Hippocampus 1 gene: PTGS2 1
36. Arecoline regulation of blood pressure Scopolamine Hydrobromide Scopolamine Hydrobromide inhibits the reaction [Arecoline results in increased regulation of blood pressure] 1: Rattus norvegicus Hippocampus 1 gene: PTGS2 1
37. Arecoline regulation of blood pressure Pirenzepine Pirenzepine inhibits the reaction [Arecoline results in increased regulation of blood pressure] 1: Rattus norvegicus Hippocampus 1 gene: PTGS2 1
38. Arecoline skeletal muscle acetylcholine-gated channel clustering AGRN Arecoline inhibits the reaction [AGRN protein results in increased skeletal muscle acetylcholine-gated channel clustering] 1: Mus musculus Muscle Fibers, Skeletal | Cell Line   1
39. Arecoline myoblast differentiation Arecoline results in decreased myoblast differentiation 1: Mus musculus Myoblasts | Cells, Cultured
2 genes: CTNNB1 | MYOG
1
40. Arecoline skeletal muscle acetylcholine-gated channel clustering Arecoline results in decreased skeletal muscle acetylcholine-gated channel clustering 1: Mus musculus Muscle Fibers, Skeletal | Cell Line   1
41. Arecoline reactive oxygen species biosynthetic process Arecoline results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Mouth | Cell Line, Tumor   1
42. Arecoline reactive oxygen species biosynthetic process coniferaldehyde coniferaldehyde inhibits the reaction [Arecoline results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens Mouth | Cell Line, Tumor   1
43. Arecoline DNA damage response, detection of DNA damage Arecoline results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Mouth | Cell Line, Tumor 1 gene: DNAJA1 1
44. Arecoline DNA damage response, detection of DNA damage coniferaldehyde coniferaldehyde inhibits the reaction [Arecoline results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Mouth | Cell Line, Tumor 1 gene: DNAJA1 1
45. Arecoline glutathione biosynthetic process Arecoline results in increased glutathione biosynthetic process 1: Homo sapiens Mouth | Cell Line, Tumor 1 gene: GSS 1
46. Arecoline mitotic cell cycle arrest 4-nitroquinolone-1-oxide | helioxanthin [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects mitotic cell cycle arrest 1: Mus musculus Mouth | Tumor Cells, Cultured 1 gene: TP53 1
47. Arecoline apoptotic process 4-nitroquinolone-1-oxide | helioxanthin [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects apoptotic process 1: Mus musculus Mouth | Tumor Cells, Cultured
9 genes: BCL2 | BRCA1 | CASP3 | CDK1 | DDIT4 | ERCC2 | MAPK1 | MAPK3 | TP53
1
48. Arecoline cell proliferation 4-nitroquinolone-1-oxide [Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased cell proliferation 1: Mus musculus Mouth | Tumor Cells, Cultured
14 genes: AR | BCL2 | CDC25C | CDK1 | CDK4 | CHRM3 | CTNNB1 | CYP1A1 | DDIT4 | EGFR | ERCC2 | PRKDC | TGFB1 | TP53
1
49. Arecoline cell proliferation 4-nitroquinolone-1-oxide | helioxanthin helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased cell proliferation] 1: Mus musculus Mouth | Tumor Cells, Cultured
14 genes: AR | BCL2 | CDC25C | CDK1 | CDK4 | CHRM3 | CTNNB1 | CYP1A1 | DDIT4 | EGFR | ERCC2 | PRKDC | TGFB1 | TP53
1
50. Arecoline positive regulation of myofibroblast differentiation Arecoline results in increased positive regulation of myofibroblast differentiation 1: Homo sapiens Mouth | Fibroblasts   1
1–50 of 634 results.