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Chemical Nicotinic Acids

1–50 of 653 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 2-(7-(3,4-dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide positive regulation of retinoic acid receptor signaling pathway Vitamin A 2-(7-(3,4-dimethoxyphenyl)imidazo(1,2-c)pyrimidin-5-ylamino)nicotinamide inhibits the reaction [Vitamin A results in increased positive regulation of retinoic acid receptor signaling pathway] 1: Mus musculus Embryo, Mammalian | Fibroblasts | Cell Line   1
2. 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide negative regulation of prostaglandin biosynthetic process 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide results in increased negative regulation of prostaglandin biosynthetic process 1: Mus musculus Sertoli Cells | Cell Line   1
3. 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide cell proliferation 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide results in decreased cell proliferation 1: Homo sapiens Breast | Cell Line, Tumor   1
4. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of blood pressure 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of blood pressure 1: Rattus norvegicus Hippocampus | Blood Vessels
2 genes: CALCA | CYP11B2
1
5. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of blood pressure methylatropine methylatropine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of blood pressure] 1: Rattus norvegicus Hippocampus | Blood Vessels
2 genes: CALCA | CYP11B2
1
6. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of membrane potential 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of membrane potential 1: Cavia porcellus Papillary Muscles   1
7. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester ion transport 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester affects ion transport 1: Rattus norvegicus Heart Ventricles
3 genes: CACNA1F | GRIA1 | GRIA2
1
8. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of blood pressure 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of blood pressure 1: Canis lupus familiaris Blood Vessels
2 genes: CALCA | CYP11B2
1
9. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester cardiac muscle contraction 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cardiac muscle contraction 1: Canis lupus familiaris Blood Vessels   1
10. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester cell cycle Nifedipine 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [Nifedipine affects cell cycle] 1: Rattus norvegicus Aorta | Connective Tissue | Fibroblasts | Cells, Cultured   1
11. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester cell proliferation Nifedipine 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [Nifedipine results in decreased cell proliferation] 1: Rattus norvegicus Aorta | Connective Tissue | Fibroblasts | Cells, Cultured   1
12. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester histamine secretion mediated by immunoglobulin Amb a I protein, Ambrosia artemisiifolia 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Amb a I protein, Ambrosia artemisiifolia results in increased histamine secretion mediated by immunoglobulin] 1: Homo sapiens Basophils   1
13. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester histamine secretion mediated by immunoglobulin Amb a I protein, Ambrosia artemisiifolia | Nitrendipine Nitrendipine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Amb a I protein, Ambrosia artemisiifolia results in increased histamine secretion mediated by immunoglobulin]] 1: Homo sapiens Basophils   1
14. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester cell death Thapsigargin 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [Thapsigargin results in increased cell death] 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
15. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester vasoconstriction 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased vasoconstriction 1: Rattus norvegicus Kidney | Arterioles   1
16. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester vasoconstriction Pinacidil Pinacidil inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased vasoconstriction] 1: Rattus norvegicus Kidney | Arterioles   1
17. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester vasoconstriction Glyburide | Pinacidil Glyburide inhibits the reaction [Pinacidil inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased vasoconstriction]] 1: Rattus norvegicus Kidney | Arterioles   1
18. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of vascular smooth muscle contraction 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of vascular smooth muscle contraction 1: Rattus norvegicus Aorta   1
19. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of vascular smooth muscle contraction Simvastatin Simvastatin inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of vascular smooth muscle contraction] 1: Rattus norvegicus Aorta   1
20. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester positive regulation of cytosolic calcium ion concentration 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased positive regulation of cytosolic calcium ion concentration 1: Rattus norvegicus Muscle, Smooth, Vascular | Cells, Cultured 1 gene: CALCA 1
21. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester positive regulation of cytosolic calcium ion concentration Simvastatin Simvastatin inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased positive regulation of cytosolic calcium ion concentration] 1: Rattus norvegicus Muscle, Smooth, Vascular | Cells, Cultured 1 gene: CALCA 1
22. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of vascular smooth muscle contraction Mevalonic Acid | Simvastatin Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of vascular smooth muscle contraction]] 1: Rattus norvegicus Aorta   1
23. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester regulation of vascular smooth muscle contraction geranylgeraniol | Simvastatin geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased regulation of vascular smooth muscle contraction]] 1: Rattus norvegicus Aorta   1
24. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester positive regulation of vasoconstriction isomethyleugenol isomethyleugenol inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased positive regulation of vasoconstriction] 1: Rattus norvegicus Aorta   1
25. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester positive regulation of vasoconstriction 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased positive regulation of vasoconstriction 1: Rattus norvegicus Aorta   1
26. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester negative regulation of cytosolic calcium ion concentration linsidomine 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [linsidomine results in increased negative regulation of cytosolic calcium ion concentration] 1: Rattus norvegicus Cerebellar Cortex | Interneurons | Cells, Cultured 1 gene: DRD2 1
27. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester calcium ion homeostasis 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester affects calcium ion homeostasis 1: Rattus norvegicus Pancreas | Cell Line
2 genes: CALCA | PTH
1
28. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester calcium ion homeostasis Quercetin [Quercetin co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] affects calcium ion homeostasis 1: Rattus norvegicus Pancreas | Cell Line
2 genes: CALCA | PTH
1
29. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester sensitization Cocaine 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Cocaine results in increased sensitization] 1: Mus musculus Ventral Tegmental Area   1
30. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester locomotion involved in locomotory behavior Cocaine 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [Cocaine results in increased locomotion involved in locomotory behavior] 1: Mus musculus Ventral Tegmental Area   1
31. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 1: Rattus norvegicus Embryo, Mammalian | Aorta, Thoracic | Muscle, Smooth, Vascular | Cell Line   1
32. 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel bisphenol A bisphenol A inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel] 1: Rattus norvegicus Embryo, Mammalian | Aorta, Thoracic | Muscle, Smooth, Vascular | Cell Line   1
33. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide mitotic cell cycle arrest 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased mitotic cell cycle arrest 1: Homo sapiens Prostate | Cell Line, Tumor   1
34. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide apoptotic process 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased apoptotic process 1: Homo sapiens Prostate | Cell Line, Tumor
7 genes: AKT1 | BAD | CASP3 | CASP8 | CASP9 | CDK1 | PARP1
1
35. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide regulation of mitochondrial membrane potential 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog affects regulation of mitochondrial membrane potential 1: Homo sapiens Prostate | Cell Line, Tumor   1
36. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide release of cytochrome c from mitochondria 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased release of cytochrome c from mitochondria 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: BAD 1
37. 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide cell proliferation Dihydrotestosterone 6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog inhibits the reaction [Dihydrotestosterone results in increased cell proliferation] 1: Homo sapiens Prostate | Cell Line, Tumor
4 genes: AKT1 | AR | BAD | CDK1
1
38. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens HCT116 Cells
3 genes: AKT1 | BCL2L1 | CDC25C
1
39. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells
3 genes: AKT1 | BCL2L1 | CDC25C
1
40. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: AKT1 | BCL2L1 | CDC25C
1
41. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens HeLa Cells
3 genes: AKT1 | BCL2L1 | CDC25C
1
42. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens Ovary | Cell Line, Tumor
3 genes: AKT1 | BCL2L1 | CDC25C
1
43. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid cell proliferation 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor
3 genes: AKT1 | BCL2L1 | CDC25C
1
44. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic cell cycle arrest 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased mitotic cell cycle arrest 1: Homo sapiens HCT116 Cells   1
45. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic cell cycle arrest 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased mitotic cell cycle arrest 1: Homo sapiens Ovary | Cell Line, Tumor   1
46. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid tubulin complex assembly 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased tubulin complex assembly     1
47. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid regulation of microtubule polymerization 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects regulation of microtubule polymerization 1: Homo sapiens HCT116 Cells   1
48. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic spindle assembly 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in decreased mitotic spindle assembly 1: Homo sapiens HCT116 Cells   1
49. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid mitotic spindle assembly 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects mitotic spindle assembly 1: Homo sapiens Ovary | Cell Line, Tumor   1
50. 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid chromosome localization 6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid affects chromosome localization 1: Homo sapiens HCT116 Cells   1
1–50 of 653 results.