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Chemical Nomifensine

Name Nomifensine
CAS Type 1 Name 8-Isoquinolinamine, 1,2,3,4-tetrahydro-2-methyl-4-phenyl-
Equivalent Terms Hoe984 | Hoe 984 | Hoe-984 | Linamiphen | Maleate, Nomifensine | Merital | Nomifensin | Nomifensine Maleate | Nomifensine Maleate (1:1)
CAS Registry Number 24526-64-5
Definition An isoquinoline derivative that prevents dopamine reuptake into synaptosomes. The maleate was formerly used in the treatment of depression. It was withdrawn worldwide in 1986 due to the risk of acute hemolytic anemia with intravascular hemolysis resulting from its use. In some cases, renal failure also developed. (From Martindale, The Extra Pharmacopoeia, 30th ed, p266)
Structure Nomifensine
Top Interacting
Genes
MeSH® ID D009627
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Isoquinolines Has associated genes Has associated diseases Nomifensine Has associated genes Has associated diseases

Top ↑ Descendants

Nomifensine Has associated genes Has associated diseases
  3',4'-dihydroxynomifensine
  3'-hydroxy-4'-methoxynomifensine
  4-hydroxy-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
  4'-hydroxy-3'-methoxynomifensine
  4'-hydroxynomifensine Has associated diseases
  psyton