These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Ma L, et al. (2016).||We reveal that specific histone modifications are associated with arsenic exposure and oxidative damage, and persistent dysregulation of these histone modifications could be a potential biomarker that evaluates the burden of arsenic exposure and predicts the adverse biological effects.||Arsenic||Study subjects||China||hair | lymphocyte | plasma | urine||8-oxo-7-hydrodeoxyguanosine | Arsenic | Malondialdehyde||Details||Arsenic Poisoning | positive regulation of histone H3-K14 acetylation | positive regulation of histone H3-K18 acetylation | positive regulation of histone H3-K36 trimethylation | positive regulation of histone H3-K9 dimethylation|
|2.||Yoshida R, et al. (2001).||We show that 8-oxodG levels in asbestos-exposed construction workers were higher (although not statistically significant), and that levels tended to correlate with duration of suspected exposure; these results suggest that even low-level asbestos exposure may induce oxidative stress.||Asbestos||Workers||Japan||urine||8-oxo-7-hydrodeoxyguanosine||Details||cellular response to oxidative stress|
|3.||Ellis JK, et al. (2012).||This study shows evidence that metabolic profiling in an uncontrolled human population is capable of identifying intermediate biomarkers of response to cadmium at true environmental concentrations, paving the way for exposome research.||Cadmium||Study subjects||United Kingdom||urine||8-oxo-7-hydrodeoxyguanosine | beta-hydroxyisovaleric acid | Citric Acid | Creatine | Creatinine||Details||cellular response to oxidative stress|
|4.||Kang S, et al. (2013).||The present study was designed to determine urinary paraben levels among pregnant women and their matching newborn infants, and the association between paraben levels and stress markers; methylparaben was detected as the highest and butylparaben as the lowest in both pregnant women and their infants; levels of ethyl paraben were 4-9 fold higher than found in pregnant women of other countries.||body mass index||ethyl-p-hydroxybenzoate | methylparaben | Parabens||Infants or newborns | Pregnant females||Korea, Republic of||urine||8-oxo-7-hydrodeoxyguanosine | butylparaben | ethyl-p-hydroxybenzoate | Malondialdehyde | methylparaben | propylparaben||Details||response to stress|