Illuminating how chemicals affect human health.
Comparative Toxicogenomics Database

• Basics
• Gene Interactions
• Genes
• Diseases
• Comps
• Pathways
• GO
• References

	Interacting Chemical	Interacting Gene	Interaction	References	Organisms
1.	Cyclic AMP	AKT1	Cyclic AMP inhibits the reaction [FGF2 results in increased activity of AKT1]	1	1
2.	AICA ribonucleotide	AKT1	AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in decreased oxidation of Fatty Acids]	1	1
3.	AICA ribonucleotide	AKT1	AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]	1	1
4.	AICA ribonucleotide	AKT1	AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]	1	1
5.	AICA ribonucleotide	AKT1	PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]]	1	1
6.	Azacitidine	AKT1	Azacitidine inhibits the reaction [TGFB1 protein results in increased phosphorylation of AKT1 protein]	1	1
7.	8-Bromo Cyclic Adenosine Monophosphate	AKT1	8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AKT1 mRNA	1	1
8.	Zalcitabine	AKT1	Zalcitabine affects the phosphorylation of AKT1 protein	1	1
9.	decitabine	AKT1	AKT1 protein inhibits the reaction [decitabine results in increased expression of TNFSF10 protein]	1	1
10.	decitabine	AKT1	decitabine results in decreased activity of AKT1 protein	2	1
11.	decitabine	AKT1	decitabine results in increased phosphorylation of AKT1 protein	1	1
12.	fludarabine	AKT1	fludarabine results in decreased phosphorylation of and results in decreased activity of AKT1 protein	1	1
13.	fludarabine	AKT1	fludarabine results in increased activity of AKT1 protein	1	1
14.	gemcitabine	AKT1	AKT1 protein affects the susceptibility to gemcitabine	1	1
15.	Cyclic GMP	AKT1	AKT1 protein inhibits the reaction [Carbon Tetrachloride results in decreased abundance of Cyclic GMP]	1	1
16.	N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine	AKT1	Pertussis Toxin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein]	1	1
17.	N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine	AKT1	wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in increased phosphorylation of AKT1 protein]	1	1
18.	(N)-methanocarba-2MeSADP	AKT1	ADRBK1 protein inhibits the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of and results in increased activity of AKT1 protein]	1	1
19.	(N)-methanocarba-2MeSADP	AKT1	(N)-methanocarba-2MeSADP results in increased phosphorylation of AKT1 protein	1	1
20.	(N)-methanocarba-2MeSADP	AKT1	PRKCZ protein inhibits the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of and results in increased activity of AKT1 protein]	1	1
21.	(N)-methanocarba-2MeSADP	AKT1	RAP1GAP protein inhibits the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of and results in increased activity of AKT1 protein]	1	1
22.	triciribine	AKT1	triciribine results in decreased phosphorylation of AKT1 protein	1	1