| 1. |
Malek AM, et al. (2015).
|
|
A potential association was found for exposure to ambient air concentrations of suspected neurotoxicant hazardous air pollutants, specifically aromatic solvents, among place of residence in 2002 and 1999 and risk of Amyotrophic Lateral Sclerosis. |
|
1,1,1-trichloroethane
| 1,1,2,2-tetrachloroethane
| 2,4-dinitrotoluene
| Acrylamide
| allyl chloride
| Arsenicals
| Benzene
| Cadmium Compounds
| Carbon Disulfide
| Carbon Tetrachloride
| Chloroform
| Cresols
| Cyanides
| ethylbenzene
| Ethylene Dibromide
| ethylene dichloride
| Ethylene Oxide
| Hexachlorobenzene
| hexachloroethane
| Hexanes
| hydrazine
| Lead
| Manganese Compounds
| Mercury Compounds
| Methyl Chloride
| Methylene Chloride
| Nickel
| Polychlorinated Biphenyls
| Selenium Compounds
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
| Vinyl Chloride
| Xylenes
|
Controls for disease:Amyotrophic Lateral Sclerosis
| Subjects with disease:Amyotrophic Lateral Sclerosis
| Study subjects |
United States |
|
1,1,1-trichloroethane
| 1,1,2,2-tetrachloroethane
| 2,4-dinitrotoluene
| Acrylamide
| allyl chloride
| Arsenicals
| Benzene
| Cadmium Compounds
| Carbon Disulfide
| Carbon Tetrachloride
| Chloroform
| Cresols
| Cyanides
| ethylbenzene
| Ethylene Dibromide
| ethylene dichloride
| Ethylene Oxide
| Hexachlorobenzene
| hexachloroethane
| Hexanes
| hydrazine
| Lead
| Manganese Compounds
| Mercury Compounds
| Methyl Chloride
| Methylene Chloride
| Nickel
| Polychlorinated Biphenyls
| Selenium Compounds
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
| Vinyl Chloride
| Xylenes
|
Details
|
Amyotrophic Lateral Sclerosis
|
| 2. |
Vermeulen R, et al. (2004).
|
|
Benzene and toluene exposures were determined in part by the degree of contact with glues, the benzene and toluene content of each glue, air movement and ventilation patterns. |
|
1,1,1-trichloroethane
| 2,2,4-trimethylpentane
| 3-xylene
| 4-xylene
| Acetone
| Benzene
| chlorobenzene
| ethyl acetate
| ethylbenzene
| ethylene dichloride
| Heptanes
| Hexanes
| Methylene Chloride
| methylethyl ketone
| methyl isobutyl ketone
| octane
| pentane
| Toluene
|
Workers |
China |
air, indoor |
1,1,1-trichloroethane
| 2,2,4-trimethylpentane
| 3-xylene
| 4-xylene
| Acetone
| Benzene
| chlorobenzene
| ethyl acetate
| ethylbenzene
| ethylene dichloride
| Heptanes
| Hexanes
| Methylene Chloride
| methylethyl ketone
| methyl isobutyl ketone
| octane
| pentane
| Toluene
|
Details
|
|
| 3. |
Sexton K, et al. (2005).
|
National Health and Nutrition Examination Survey (NHANES) | The School Health Initiative: Environment, Learning, Disease (SHIELD) |
Results indicate that childhood exposures to some compounds equaled or exceeded volatile organic compound (VOC) exposures of adults, including smokers, in an earlier national survey, and that within-child variability was greater than between-child variability for 7 of 11 individual VOCs. |
|
1,1,1-trichloroethane
| 2-xylene
| 3-xylene
| 4-dichlorobenzene
| 4-xylene
| Benzene
| Carbon Tetrachloride
| ethylbenzene
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Children | Study subjects |
United States |
blood |
1,1,1-trichloroethane
| 2-xylene
| 3-xylene
| 4-dichlorobenzene
| 4-xylene
| Benzene
| Carbon Tetrachloride
| ethylbenzene
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Details
|
|
| 4. |
Sexton K, et al. (2007).
|
|
Our aim was to compare and rank relative health risks of 179 air pollutants in Houston using an evidence-based approach supplemented by the expert judgment of a panel of academic scientists. |
|
1,1,2,2-tetrachloroethane
| 1,3-butadiene
| 1,6-hexamethylene diisocyanate
| Acetaldehyde
| Acrolein
| acrylic acid
| Acrylonitrile
| Arsenicals
| Benzene
| Carbon Tetrachloride
| Chlorine
| chromium hexavalent ion
| Ethylene Dibromide
| ethylene dichloride
| Ethylene Oxide
| Formaldehyde
| naphthalene
| Ozone
| Particulate Matter
| Vehicle Emissions
| Vinyl Chloride
|
Study subjects |
United States |
|
|
Details
|
Disorders of Environmental Origin
| Neoplasms
|
| 5. |
Loh MM, et al. (2007).
|
|
In this study we compared cancer risks from organic hazardous air pollutants (HAPs) based on total personal exposure summed across different microenvironments and exposure pathways. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1,3-dichloro-1-propene
| 4-dichlorobenzene
| Acetaldehyde
| anthracene
| benz(a)anthracene
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| Carbon Tetrachloride
| Chloroform
| chrysene
| Dioxins
| Ethylene Dibromide
| ethylene dichloride
| fluoranthene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Methylene Chloride
| naphthalene
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Study subjects |
United States |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1,3-dichloro-1-propene
| 4-dichlorobenzene
| Acetaldehyde
| anthracene
| benz(a)anthracene
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| Carbon Tetrachloride
| Chloroform
| chrysene
| Dioxins
| Ethylene Dibromide
| ethylene dichloride
| fluoranthene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Methylene Chloride
| naphthalene
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Details
|
Neoplasms
|
| 6. |
Aquilina NJ, et al. (2010).
|
Measurement and Modelling of Air Toxic Concentrations for Health Effect Studies Project (MATCH) |
The objective of this study was to analyse environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbon (PAH) metabolites in urine samples of non-occupationally exposed non-smoker adult subjects and to establish relationships between airborne exposures and urinary concentrations in order to assess the suitability of the studied metabolites as biomarkers of PAH and ETS, study the use of 3-ethenypyridine as ETS tracer, and link ETS scenarios with exposures to carcinogenic PAH and volatile organic compounds. |
tobacco |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-vinylpyridine
| acenaphthene
| acenaphthylene
| anthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| coronene
| fluoranthene
| fluorene
| hydroxycotinine
| indeno(1,2,3-cd)pyrene
| naphthalene
| Nicotine
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Study subjects |
United Kingdom |
urine |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-vinylpyridine
| acenaphthene
| acenaphthylene
| anthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| coronene
| fluoranthene
| fluorene
| hydroxycotinine
| indeno(1,2,3-cd)pyrene
| naphthalene
| Nicotine
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Details
|
|
| 7. |
von Ehrenstein OS, et al. (2016).
|
California Cancer Registry |
Our data suggest that in utero and infancy exposures to air toxics generated by industrial and road traffic sources may increase the risk of primitive neuroectodermal tumor and medulloblastoma, with limited support for increased risks for astrocytoma in children up to age 6. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 2-dichlorobenzene
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| Chloroform
| Chromium
| chromium hexavalent ion
| ethylbenzene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Lead
| Methylene Chloride
| Nickel
| Polycyclic Aromatic Hydrocarbons
| Selenium
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Study subjects |
United States |
air |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 2-dichlorobenzene
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| Chloroform
| Chromium
| chromium hexavalent ion
| ethylbenzene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Lead
| Methylene Chloride
| Nickel
| Polycyclic Aromatic Hydrocarbons
| Selenium
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Details
|
Astrocytoma
| Medulloblastoma
| Neuroectodermal Tumors, Primitive
|
| 8. |
Choi H, et al. (2008).
|
|
Prenatal polycyclic aromatic hydrocarbon exposure is likely to contribute to the occurrence of small size for gestational age as well as preterm births among African Americans. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
|
Pregnant females |
United States |
air |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
|
Details
|
Fetal Growth Retardation
| Premature Birth
| Prenatal Exposure Delayed Effects
|
| 9. |
Tonne CC, et al. (2004).
|
|
In this study, we examined levels of exposures to polycyclic aromatic hydrocarbons and tested for associations with potential predictor variables collected from questionnaires addressing socioeconomic factors and day-to-day activities during pregnancy as well as activities and environmental exposures during the 48-hr monitoring period. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Pregnant females |
Croatia|France|
Italy|United States |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Details
|
|
| 10. |
Varlet V, et al. (2015).
|
|
We analyzed 42 models from 14 brands of refill liquids for e-cigarettes for the presence of micro-organisms, diethylene glycol, ethylene glycol, hydrocarbons, ethanol, aldehydes, tobacco-specific nitrosamines, and solvents. |
|
1,1-diethoxyethane
| 1,3-butadiene
| 1-Butanol
| 1-Propanol
| 2-butenal
| 2-methylbenzaldehyde
| 3-methylbenzaldehyde
| 4-cymene
| 4-methylbenzaldehyde
| Acetaldehyde
| Acetoin
| Acetone
| Acrolein
| alpha-pinene
| benzaldehyde
| beta-pinene
| butyraldehyde
| Cyclohexane
| Diacetyl
| diethylene glycol
| Ethanol
| ethyl acetate
| Ethylene Glycol
| ethyl propionate
| Formaldehyde
| gamma-terpinene
| Hydrocarbons
| isobutyl acetate
| isovalerylaldehyde
| Limonene
| n-hexanal
| Nitrosamines
| pentanal
| propionaldehyde
|
|
Switzerland |
e-cigarette, liquid |
1,1-diethoxyethane
| 1,3-butadiene
| 1-Butanol
| 1-Propanol
| 2-butenal
| 2-methylbenzaldehyde
| 3-methylbenzaldehyde
| 4-cymene
| 4-methylbenzaldehyde
| Acetaldehyde
| Acetoin
| Acetone
| Acrolein
| alpha-pinene
| benzaldehyde
| beta-pinene
| butyraldehyde
| Cyclohexane
| Diacetyl
| diethylene glycol
| Ethanol
| ethyl acetate
| Ethylene Glycol
| ethyl propionate
| Formaldehyde
| gamma-terpinene
| Hydrocarbons
| isobutyl acetate
| isovalerylaldehyde
| Limonene
| n-hexanal
| Nitrosamines
| pentanal
| propionaldehyde
|
Details
|
|
| 11. |
Hedley AJ, et al. (2006).
|
|
In a 2002-2003 World Health Organization exposure study, 13 pools of breast milk comprising samples from 316 primiparous women in Hong Kong in 2002 were analyzed by gas chromatography/mass spectrometry for 29 polychlorinated dibenzo-para-dioxins /dibenzofurans and dioxin-like poly-chlorinated biphenyls congeners. |
|
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 1,2,3,6,7,8-hexachlorodibenzodioxin
| 1,2,3,7,8-pentachlorodibenzofuran
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,4'5-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| 2,3,7,8-tetrachlorodibenzofuran
| 3,4,3',4'-tetrachlorobiphenyl
| 3,4,5,3',4',5'-hexachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| Benzofurans
| octachlorodibenzofuran
| Polychlorinated Biphenyls
| Polychlorinated Dibenzodioxins
| polychlorodibenzofuran
| Tetrachlorodibenzodioxin
|
Mothers |
Hong Kong |
milk, human |
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 1,2,3,6,7,8-hexachlorodibenzodioxin
| 1,2,3,7,8-pentachlorodibenzofuran
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,4'5-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| 2,3,7,8-tetrachlorodibenzofuran
| 3,4,3',4'-tetrachlorobiphenyl
| 3,4,5,3',4',5'-hexachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| Benzofurans
| octachlorodibenzofuran
| Polychlorinated Biphenyls
| Polychlorinated Dibenzodioxins
| polychlorodibenzofuran
| Tetrachlorodibenzodioxin
|
Details
|
|
| 12. |
Warner M, et al. (2014).
|
Seveso Women's Health Study (SWHS) |
We measured individual 2,3,7,8-tetrachlorodibenzo-p-dioxin and total toxic equivalent concentrations in serum collected approximately twenty years after the 1976 explosion for a sample of the Seveso Women's Health Study cohort. |
|
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 1,2,3,6,7,8-hexachlorodibenzodioxin
| 1,2,3,7,8-pentachlorodibenzofuran
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| 2,3,7,8-tetrachlorodibenzofuran
| 3,4,3',4'-tetrachlorobiphenyl
| 3,4,5,3',4',5'-hexachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| octachlorodibenzo-4-dioxin
| octachlorodibenzofuran
| Polychlorinated Biphenyls
| Tetrachlorodibenzodioxin
|
Controls for disease:Chloracne
| Subjects with disease:Chloracne
| Study subjects |
Italy |
serum |
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 1,2,3,6,7,8-hexachlorodibenzodioxin
| 1,2,3,7,8-pentachlorodibenzofuran
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| 2,3,7,8-tetrachlorodibenzofuran
| 3,4,3',4'-tetrachlorobiphenyl
| 3,4,5,3',4',5'-hexachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| octachlorodibenzo-4-dioxin
| octachlorodibenzofuran
| Polychlorinated Biphenyls
| Tetrachlorodibenzodioxin
|
Details
|
|
| 13. |
Lee DH, et al. (2007).
|
National Health and Nutrition Examination Survey (NHANES) |
This study suggests that the prevalence of a cluster of cardiovascular risk factors relates to background exposure to a mixture of persistent organic pollutants, several of which are also related to the prevalence of diabetes. |
|
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4',5-tetrachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| Dibenzofurans, Polychlorinated
| Hydrocarbons, Chlorinated
| Pesticides
| Polychlorinated Biphenyls
| Polychlorinated Dibenzodioxins
|
Study subjects |
United States |
|
|
Details
|
Insulin Resistance
| Metabolic Syndrome
| cholesterol metabolic process
| regulation of blood pressure
| triglyceride metabolic process
|
| 14. |
Pless-Mulloli T, et al. (2005).
|
|
Long term residency near heavy and chemical industry did not have an effect on women's body burden of polychlorinated dibenzo-dioxins and furans and polychlorinated biphenyls on Teesside, UK. |
|
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 1,2,3,6,7,8-hexachlorodibenzodioxin
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| Benzofurans
| Dibenzofurans, Polychlorinated
| octachlorodibenzo-4-dioxin
| Polychlorinated Biphenyls
| Polychlorinated Dibenzodioxins
| Tetrachlorodibenzodioxin
|
Study subjects |
United Kingdom |
blood |
1,2,3,4,6,7,8-heptachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzodioxin
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 1,2,3,6,7,8-hexachlorodibenzodioxin
| 1,2,3,7,8-pentachlorodibenzo-p-dioxin
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| Benzofurans
| Dibenzofurans, Polychlorinated
| octachlorodibenzo-4-dioxin
| Polychlorinated Biphenyls
| Polychlorinated Dibenzodioxins
| Tetrachlorodibenzodioxin
|
Details
|
|
| 15. |
Turyk ME, et al. (2007).
|
National Health and Nutrition Examination Survey (NHANES) |
In the adult participants of NHANES from 1999 to 2002, total thyroxine was negatively associated with serum dioxin-like toxic equivalents in a dose-dependent fashion, with stronger associations in women than men. |
age | sex |
1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| 2,4,4',5-tetrachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 3,4,5,3',4',5'-hexachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| Benzofurans
| dibenzodioxin
| Dichlorodiphenyl Dichloroethylene
| Dioxins and Dioxin-like Compounds
| Hydrocarbons, Chlorinated
| PCB 180
| Polychlorinated Biphenyls
|
Study subjects |
United States |
serum |
1,2,3,4,6,7,8-heptachlorodibenzofuran
| 1,2,3,4,7,8-hexachlorodibenzofuran
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,3,4,7,8-pentachlorodibenzofuran
| 2,4,4',5-tetrachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 3,4,5,3',4',5'-hexachlorobiphenyl
| 3,4,5,3',4'-pentachlorobiphenyl
| Benzofurans
| dibenzodioxin
| Dichlorodiphenyl Dichloroethylene
| PCB 180
| Polychlorinated Biphenyls
| Thyrotropin
| Thyroxine
|
Details
|
thyroid hormone metabolic process
|
| 16. |
Mi T, et al. (2013).
|
|
We describe two cases of acute toxic leukoencephalopathy in migrant workers who were occupationally exposed to organic solvents in construction materials. |
|
1,2,3-trichloropropane
| Solvents
| Toluene
|
Workers |
China |
blood | urine |
1,2,3-trichloropropane
| Benzoic Acid
|
Details
|
Leukoencephalopathies
| Neurotoxicity Syndromes
| Occupational Diseases
|
| 17. |
Dodson RE, et al. (2015).
|
California Household Exposure Study (CAHES) |
We collected house dust and indoor air samples in 49 California homes and analyzed for 76 semivolatile organic compounds-phthalates, polybrominated diphenyl ethers, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, and pesticides. |
|
1,2,5,6-dibenzanthracene
| 1-methylphenanthrene
| 1-nitropyrene
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| 2-methylphenanthrene
| 2-phenylphenol
| 4,6-dimethyldibenzothiophene
| 4-nitrotoluene
| acenaphthene
| acenaphthylene
| alachlor
| Aldrin
| anthracene
| Atrazine
| bendiocarb
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(j)fluoranthene
| benzo(k)fluoranthene
| benzothiophene
| butylbenzyl phthalate
| Carbaryl
| Carbofuran
| Chlordan
| Chlorpyrifos
| chrysene
| cyanazine
| cypermethrin
| DDT
| Diazinon
| dibenzo(a,e)pyrene
| dibenzothiophene
| Dibutyl Phthalate
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Dicofol
| dicyclohexyl phthalate
| Dieldrin
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| di-n-hexyl phthalate
| di-n-octyl phthalate
| di-n-pentyl phthalate
| di-n-propylphthalate
| dioctyl adipate
| Endrin
| fluoranthene
| fluorene
| Heptachlor
| Hexachlorocyclohexane
| indeno(1,2,3-cd)pyrene
| Malathion
| Methoxychlor
| Methyl Parathion
| metolachlor
| nitrofen
| Parathion
| pentabrominated diphenyl ether 100
| Permethrin
| phenanthrene
| Phenanthrenes
| Piperonyl Butoxide
| prometone
| Propoxur
| pyrene
| Simazine
| tetrachloroisophthalonitrile
| Trifluralin
| tris(2,3-dibromopropyl)phosphate
|
|
United States |
dust |
1,2,5,6-dibenzanthracene
| 1-methylphenanthrene
| 1-nitropyrene
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| 2-methylphenanthrene
| 2-phenylphenol
| 4,6-dimethyldibenzothiophene
| 4-nitrotoluene
| acenaphthene
| acenaphthylene
| alachlor
| Aldrin
| anthracene
| Atrazine
| bendiocarb
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(j)fluoranthene
| benzo(k)fluoranthene
| benzothiophene
| butylbenzyl phthalate
| Carbaryl
| Carbofuran
| Chlordan
| Chlorpyrifos
| chrysene
| cyanazine
| cypermethrin
| DDT
| Diazinon
| dibenzo(a,e)pyrene
| dibenzothiophene
| Dibutyl Phthalate
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Dicofol
| dicyclohexyl phthalate
| Dieldrin
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| di-n-hexyl phthalate
| di-n-octyl phthalate
| di-n-pentyl phthalate
| di-n-propylphthalate
| dioctyl adipate
| Endrin
| fluoranthene
| fluorene
| Heptachlor
| Hexachlorocyclohexane
| indeno(1,2,3-cd)pyrene
| Malathion
| Methoxychlor
| Methyl Parathion
| metolachlor
| nitrofen
| Parathion
| pentabrominated diphenyl ether 100
| Permethrin
| phenanthrene
| Phenanthrenes
| Piperonyl Butoxide
| prometone
| Propoxur
| pyrene
| Simazine
| tetrachloroisophthalonitrile
| Trifluralin
| tris(2,3-dibromopropyl)phosphate
|
Details
|
|
| 18. |
Schreder ED, et al. (2014).
|
|
Levels of flame retardants in house dust and a transport pathway from homes to the outdoor environment were investigated in communities near the Columbia River in Washington state. |
|
1,2-bis(2,4,6-tribromophenoxy)ethane
| 2,2',3,3',4,4',5,5',6-nonabromodiphenyl ether
| 2,2',3,4,4',5',6-heptabromodiphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2-ethylhexyl 2,3,4,5-tetrabromobenzoate
| bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate
| decabromobiphenyl ether
| decabromodiphenyl ethane
| Flame Retardants
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| hexabromocyclododecane
| hexabromodiphenyl ether 154
| pentabrominated diphenyl ether 100
| pentabromodiphenyl ether
| tetrabromobisphenol A
| tribromodiphenyl ether 28
| tris(1,3-dichloro-2-propyl)phosphate
| tris(1-chloro-2-propyl)phosphate
| tris(chloroethyl)phosphate
|
|
United States |
dust | waste water, laundry |
1,2-bis(2,4,6-tribromophenoxy)ethane
| 2,2',3,3',4,4',5,5',6-nonabromodiphenyl ether
| 2,2',3,4,4',5',6-heptabromodiphenyl ether
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2-ethylhexyl 2,3,4,5-tetrabromobenzoate
| bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate
| decabromobiphenyl ether
| decabromodiphenyl ethane
| Flame Retardants
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| hexabromocyclododecane
| hexabromodiphenyl ether 154
| pentabrominated diphenyl ether 100
| pentabromodiphenyl ether
| tetrabromobisphenol A
| tribromodiphenyl ether 28
| tris(1,3-dichloro-2-propyl)phosphate
| tris(1-chloro-2-propyl)phosphate
| tris(chloroethyl)phosphate
|
Details
|
|
| 19. |
Stapleton HM, et al. (2009).
|
|
We designed this study to identify potential organophosphate flame retardant chemicals currently being used in polyurethane foam in residential and office furniture purchased in the United States. |
|
1,2-bis(2,4,6-tribromophenoxy)ethane
| 2-ethylhexyl 2,3,4,5-tetrabromobenzoate
| bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate
| Flame Retardants
| Halogenated Diphenyl Ethers
| hexabromocyclododecane
| triphenyl phosphate
| tris(1,3-dichloro-2-propyl)phosphate
| tris(1-chloro-2-propyl)phosphate
|
Children | Study subjects |
United States |
dust |
1,2-bis(2,4,6-tribromophenoxy)ethane
| 2-ethylhexyl 2,3,4,5-tetrabromobenzoate
| bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate
| Flame Retardants
| Halogenated Diphenyl Ethers
| hexabromocyclododecane
| triphenyl phosphate
| tris(1,3-dichloro-2-propyl)phosphate
| tris(1-chloro-2-propyl)phosphate
|
Details
|
|
| 20. |
Ruckart PZ, et al. (2015).
|
|
Findings suggested possible associations between male breast cancer and being stationed at Camp Lejeune and cumulative exposure to tetrachloroethylene, t-1,2 dichloroethylene, and vinyl chloride. |
|
1,2-dichloroethylene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Controls for disease:Breast Neoplasms
| Subjects with disease:Breast Neoplasms
| Veterans |
United States |
|
1,2-dichloroethylene
| Tetrachloroethylene
| Trichloroethylene
|
Details
|
Breast Neoplasms
|
| 21. |
Goniewicz ML, et al. (2018).
|
Population Assessment of Tobacco and Health (PATH) Study |
These findings provide evidence that using combusted tobacco cigarettes alone or in combination with e-cigarettes is associated with higher concentrations of potentially harmful tobacco constituents in comparison with using e-cigarettes alone. |
tobacco |
1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-butenal
| 2-hydroxyfluorene
| 2-naphthol
| 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol
| Acrolein
| Acrylamide
| Acrylonitrile
| Anabasine
| anatabine
| Arsenic
| Benzene
| Beryllium
| Cadmium
| Carbon Disulfide
| Cobalt
| Cotinine
| cotinine-N-oxide
| Dimethylformamide
| ethylbenzene
| Ethylene Oxide
| Fluorenes
| hydroxycotinine
| Isocyanates
| isoprene
| Lead
| mandelic acid
| Manganese
| nicotine 1-N-oxide
| Nicotine
| N'-nitrosoanabasine
| N'-nitrosoanatabine
| N'-nitrosonornicotine
| norcotinine
| nornicotine
| Phenanthrenes
| propylene oxide
| Strontium
| Styrene
| Thallium
| Toluene
| Uranium
| Vinyl Chloride
| Xylenes
|
Study subjects |
United States |
urine |
1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-butenal
| 2-hydroxyfluorene
| 2-methylhippuric acid
| 2-naphthol
| 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol
| Acrolein
| Acrylamide
| Acrylonitrile
| Anabasine
| anatabine
| Arsenic
| Benzene
| Beryllium
| Cadmium
| Carbon Disulfide
| Cobalt
| Cotinine
| cotinine-N-oxide
| Dimethylformamide
| Fluorenes
| Hippurates
| hydroxycotinine
| isoprene
| Lead
| mandelic acid
| Manganese
| N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
| N-acetyl-S-(2-cyanoethyl)cysteine
| N-acetyl-S-(2-hydroxyethyl)cysteine
| nicotine 1-N-oxide
| Nicotine
| N'-nitrosoanabasine
| N'-nitrosoanatabine
| N'-nitrosonornicotine
| norcotinine
| nornicotine
| Phenanthrenes
| phenylglyoxylic acid
| propylene oxide
| S-(3-hydroxypropyl)cysteine N-acetate
| S-benzyl-N-acetyl-L-cysteine
| Strontium
| Thallium
| Uranium
|
Details
|
|
| 22. |
Shahab L, et al. (2017).
|
|
This study assessed whether long-term e-cigarette (EC)-only, nicotine replacement therapy (NRT)-only, dual cigarette-EC or dual cigarette-NRT use is associated with differences in metabolites of a) nicotine; b) tobacco-specific nitrosaminess and c) volatile organic compounds (VOC) compared with cigarette-only smokers. |
tobacco |
1,3-butadiene
| 2-butenal
| 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
| Acrolein
| Acrylamide
| Acrylonitrile
| Anabasine
| anatabine
| Benzene
| Carbon Disulfide
| Cyanides
| Dimethylformamide
| ethylbenzene
| Ethylene Oxide
| Nicotine
| N'-nitrosoanabasine
| N'-nitrosoanatabine
| propylene oxide
| Styrene
| Vinyl Chloride
| Xylenes
|
Study subjects |
United Kingdom |
saliva | urine |
1,3-butadiene
| 2-amino-delta(2)-thiazoline-4-carboxylic acid
| 2-butenal
| 2-methylhippuric acid
| 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol
| Acrolein
| Acrylamide
| Acrylonitrile
| Anabasine
| anatabine
| Benzene
| Cotinine
| cotinine-N-oxide
| Dimethylformamide
| Hippurates
| hydroxycotinine
| mandelic acid
| muconic acid
| N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
| nicotine 1-N-oxide
| Nicotine
| N'-nitrosoanabasine
| N'-nitrosoanatabine
| norcotinine
| nornicotine
| phenylglyoxylic acid
| propylene oxide
| raphanusamic acid
| S-(3-hydroxypropyl)cysteine N-acetate
| Styrene
|
Details
|
|
| 23. |
Goniewicz ML, et al. (2017).
|
|
This study showed for the first time that after switching from tobacco to e-cigarettes, nicotine exposure remains unchanged, while exposure to selected carcinogens and toxicants is substantially reduced. |
tobacco |
1,3-butadiene
| 2-butenal
| 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
| Acrolein
| Acrylamide
| Acrylonitrile
| Benzene
| Carbon Monoxide
| Ethylene Oxide
| fluorene
| naphthalene
| Nicotine
| phenanthrene
| propylene oxide
| pyrene
|
Study subjects |
Poland |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-hydroxy-1-methylpropylmercapturic acid
| 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol
| Acetylcysteine
| Carbon Monoxide
| Cotinine
| cotinine-N-oxide
| fluorene
| hydroxycotinine
| N-acetyl-S-(2-hydroxyethyl)cysteine
| nicotine 1-N-oxide
| Nicotine
| norcotinine
| nornicotine
| phenanthrene
| S-phenyl-N-acetylcysteine
|
Details
|
|
| 24. |
Rull RP, et al. (2006).
|
|
Data on two case-control study populations of infants with neural tube defects (NTDs) and nonmalformed controls delivered in California between 1987 and 1991 were pooled to investigate whether maternal residential proximity to applications of specific pesticides or physicochemical groups of pesticides during early gestation increases the risk of these malformations. |
|
1,3-dichloro-1-propene
| Amides
| Benomyl
| Benzimidazoles
| Captan
| Chlorpyrifos
| devrinol
| Dimethoate
| Disulfoton
| Methomyl
| methyl carbamate
| methyl demeton
| Naled
| Organophosphorus Compounds
| vendex
|
Infants or newborns |
United States |
|
1,3-dichloro-1-propene
| Amides
| Benomyl
| Benzimidazoles
| Captan
| Chlorpyrifos
| devrinol
| Dimethoate
| Disulfoton
| Methomyl
| methyl carbamate
| methyl demeton
| Naled
| Organophosphorus Compounds
| vendex
|
Details
|
Anencephaly
| Neural Tube Defects
| Spinal Dysraphism
|
| 25. |
Kponee KZ, et al. (2018).
|
|
In this pilot study, we measured indoor volatile organic compound (VOC) concentrations in the indoor air of 20 households in Ogale, an Ogoniland community whose groundwater system is contaminated with benzene at levels 900 times the World Health Organization guidelines and evaluated self-reported health conditions and predicted cancer risks and hazards from inhalation exposure to VOCs. |
|
1,4-dioxane
| 2,5-dimethylfuran
| 2-xylene
| 3-xylene
| 4-cymene
| 4-dichlorobenzene
| 4-xylene
| Benzene
| Carbon Tetrachloride
| cumene
| ethylbenzene
| hemimellitene
| Limonene
| mesitylene
| naphthalene
| n-propylbenzene
| pseudocumene
| sec-butylbenzene
| Styrene
| Toluene
| Xylenes
|
Study subjects |
Nigeria |
air |
1,4-dioxane
| 2,5-dimethylfuran
| 2-xylene
| 3-xylene
| 4-cymene
| 4-dichlorobenzene
| 4-xylene
| Benzene
| Carbon Tetrachloride
| cumene
| ethylbenzene
| hemimellitene
| Limonene
| mesitylene
| naphthalene
| n-propylbenzene
| pseudocumene
| sec-butylbenzene
| Styrene
| Toluene
| Xylenes
|
Details
|
Neoplasms
|
| 26. |
Kalkbrenner AE, et al. (2018).
|
Autism Genetic Resource Exchange (AGRE) |
Some air toxics were associated with autism spectrum disorder risk and severity, including some traffic-related air pollutants and newly-reported associations, but other previously reported associations with metals and volatile organic compounds were not reproducible. |
|
1,4-dioxane
| 4,4'-diphenylmethane diisocyanate
| 4-dichlorobenzene
| benzidine
| bromoform
| Carbon Disulfide
| chlorobenzene
| Dibenzofurans
| methyl tert-butyl ether
| propionaldehyde
| Urethane
|
Subjects with disease:Autism Spectrum Disorder
|
United States |
|
|
Details
|
Autism Spectrum Disorder
|
| 27. |
Pronk A, et al. (2006).
|
|
The aim of this study was to assess which compounds contribute to isocyanate exposure in car body repair shops and industrial painting companies, and to identify tasks with a high risk of isocyanate exposure. |
|
1,6-hexamethyleneaminoisocyanate
| 1,6-hexamethylene diisocyanate
| 2,6-diisocyanatotoluene
| 4,4'-diphenylmethane diisocyanate
| Biuret
| ethyl isocyanate
| Isocyanates
| isophorone diisocyanate
| methyl isocyanate
| phenyl isocyanate
| Toluene 2,4-Diisocyanate
|
Workers |
Netherlands |
|
1,6-hexamethyleneaminoisocyanate
| 1,6-hexamethylene diisocyanate
| 2,6-diisocyanatotoluene
| 4,4'-diphenylmethane diisocyanate
| Biuret
| ethyl isocyanate
| Isocyanates
| isophorone diisocyanate
| methyl isocyanate
| phenyl isocyanate
| Toluene 2,4-Diisocyanate
|
Details
|
|
| 28. |
Svedberg UR, et al. (2004).
|
|
High levels of hexanal and carbon monoxide were strongly associated with storage of wood pellets and may constitute an occupational and domestic health hazard. |
|
1-Butanol
| 2-heptenal
| Acetone
| Aldehydes
| butyraldehyde
| Carbon Monoxide
| decanaldehyde
| formic acid
| heptanal
| Methanol
| n-hexanal
| nonanal
| pentanal
| Terpenes
| Toluene
|
Study subjects |
Sweden |
air |
1-Butanol
| 2-heptenal
| Acetone
| Aldehydes
| butyraldehyde
| Carbon Monoxide
| decanaldehyde
| formic acid
| heptanal
| Methanol
| n-hexanal
| nonanal
| pentanal
| Terpenes
| Toluene
|
Details
|
|
| 29. |
Aszyk J, et al. (2017).
|
|
A gas chromatography-electron ionization-mass spectometry method was developed and validated for the simultaneous determination of 46 commonly used flavour additives in e-liquids. |
|
1-hexanol
| 3,4-dihydrocoumarin
| 3-hexen-1-ol
| 4-Butyrolactone
| alpha-terpineol
| anisyl acetate
| benzaldehyde
| benzyl acetate
| Benzyl Alcohol
| citronellol
| decan-4-olide
| decanaldehyde
| ethyl hexanoate
| Eugenol
| Furaldehyde
| furfuryl alcohol
| isoamyl acetate
| Limonene
| linalyl acetate
| methyl acetate
| n-pentanol
| raspberry ketone
|
|
Poland |
e-cigarette, liquid |
1-hexanol
| 3,4-dihydrocoumarin
| 3-hexen-1-ol
| 4-Butyrolactone
| alpha-terpineol
| anisyl acetate
| benzaldehyde
| benzyl acetate
| Benzyl Alcohol
| citronellol
| decan-4-olide
| decanaldehyde
| ethyl hexanoate
| Eugenol
| Furaldehyde
| furfuryl alcohol
| isoamyl acetate
| Limonene
| linalyl acetate
| methyl acetate
| n-pentanol
| raspberry ketone
|
Details
|
|
| 30. |
Deng Q, et al. (2014).
|
Coke-oven Workers (COW) Cohort |
We identified five potentially polycyclic aromatic hydrocarbon (PAH)-associated miRNAs in plasma, and the same miRNAs were associated with a marker of chromosome damage in coke oven workers, suggesting that miRNAs might be a novel mechanism mediating the effects of PAH exposure on chromosome damage. |
alcohol drinking |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Workers |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
miRNA metabolic process
|
| 31. |
Li J, et al. (2018).
|
Coke-oven Workers (COW) Cohort | Shiyan (SY) Cohort | Wuhan-Zhuhai (WHZH) Cohort |
Our findings suggest that exposure to polycyclic aromatic hydrocarbons may be associated with an adverse impact on human aging and epigenetic alterations in Chinese populations. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Study subjects |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
aging
| DNA methylation
|
| 32. |
Yang B, et al. (2016).
|
|
Our results indicated polycyclic aromatic hydrocarbons exposure was associated with plasma cytokines, and higher cytokines were associated with decreased heart rate variability, but additional human and potential mechanistic studies are needed. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Workers |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| ALCAM
| BDNF
| CRP
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
Cardiovascular Diseases
| gene expression
|
| 33. |
Li Z, et al. (2012).
|
|
This study aimed to investigate the excretion half-life of 1-hydroxypyrene (1-PYR), the most used biomarker for polycyclic aromatic hydrocarbon (PAH) exposure, and 9 other mono-hydroxylated metabolites following a dietary exposure in 9 non-smoking volunteers with no occupational exposure to PAHs. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
|
Study subjects |
United States |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
|
Details
|
|
| 34. |
Barraza-Villarreal A, et al. (2014).
|
|
Biomarkers of polycyclic aromatic hydrocarbons exposure were inversely associated with lung function and decrease of pH of exhaled breath condensate as a marker of airway inflammation in Mexican schoolchildren. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Children |
Mexico |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
|
Details
|
respiratory system process
|
| 35. |
Zhou Y, et al. (2016).
|
Wuhan-Zhuhai (WHZH) Cohort |
Total and specific urinary polycyclic aromatic hydrocarbons metabolites were associated with lung function reduction in a general Chinese population. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Study subjects |
China |
urine |
Polycyclic Aromatic Hydrocarbons
|
Details
|
respiratory system process
|
| 36. |
Ji G, et al. (2010).
|
Nanjing Medical University Infertile Study |
These findings provided the first evidence that polymorphisms of XRCC1 may modify sperm Polycyclic Aromatic Hydrocarbons-DNA adduct levels and may be useful biomarkers to identify individuals susceptible to DNA damage resulting from PAHs exposure. |
genetics |
1-hydroxypyrene
|
Subjects with disease:Infertility, Male
|
China |
urine |
1-hydroxypyrene
|
Details
|
Infertility, Male
|
| 37. |
Tuakuila J, et al. (2013).
|
|
This study reveals the high pyrene (PAH) exposure of the Kinshasa population requiring the determination of PAH concentrations in ambient air of Kinshasa and limits values for the protection of human health. |
tobacco |
1-hydroxypyrene
|
Study subjects |
Congo, the Democratic Republic of the |
urine |
1-hydroxypyrene
|
Details
|
|
| 38. |
Trejo-Acevedo A, et al. (2012).
|
|
The aim of this study was to evaluate the exposure levels to persistent organic pollutants and 1-hydroxypyrene in children living in an endemic malaria zone in Mexico. |
|
1-hydroxypyrene
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',3,4',5,5',6-heptachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,2',3',4'-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Aldrin
| alpha-hexachlorocyclohexane
| beta-hexachlorocyclohexane
| Chlordan
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hexachlorocyclohexane
| Mirex
| nonachlor
| PCB 180
| Polychlorinated Biphenyls
|
Children |
Mexico |
plasma | urine |
1-hydroxypyrene
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',3,4',5,5',6-heptachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,2',3',4'-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Aldrin
| alpha-hexachlorocyclohexane
| beta-hexachlorocyclohexane
| Chlordan
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hexachlorocyclohexane
| Mirex
| nonachlor
| PCB 180
| Polychlorinated Biphenyls
|
Details
|
|
| 39. |
Woodruff TJ, et al. (2011).
|
National Health and Nutrition Examination Survey (NHANES) |
Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. |
|
1-hydroxypyrene
| 2,2',4,4',5,5'-hexabrominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2-naphthol
| 4-dichlorobenzene
| Benzene
| bisphenol A
| Cadmium
| Cotinine
| DDT
| Dichlorodiphenyl Dichloroethylene
| diethyl phosphate
| dimethyl phosphate
| fluoren-9-ol
| Hexachlorobenzene
| Lead
| Mercury
| methyl tert-butyl ether
| mono-benzyl phthalate
| monobutyl phthalate
| mono-isobutyl phthalate
| O,O-dimethyl phosphorodithioate
| O,O-dimethyl phosphorothionate
| oxybenzone
| PCB 180
| perchlorate
| perfluorooctane sulfonic acid
| perfluorooctanoic acid
| thiophosphoric acid
| Toluene
| Triclosan
|
Pregnant females | Study subjects |
United States |
blood | serum | urine |
1-hydroxypyrene
| 2,2',4,4',5,5'-hexabrominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2-naphthol
| 4-dichlorobenzene
| Benzene
| bisphenol A
| Cadmium
| Cotinine
| DDT
| Dichlorodiphenyl Dichloroethylene
| diethyl phosphate
| dimethyl phosphate
| fluoren-9-ol
| Hexachlorobenzene
| Lead
| Mercury
| methyl tert-butyl ether
| mono-benzyl phthalate
| monobutyl phthalate
| mono-isobutyl phthalate
| O,O-dimethyl phosphorodithioate
| O,O-dimethyl phosphorothionate
| oxybenzone
| PCB 180
| perchlorate
| perfluorooctane sulfonic acid
| perfluorooctanoic acid
| thiophosphoric acid
| Toluene
| Triclosan
|
Details
|
|
| 40. |
Johnson NM, et al. (2010).
|
|
Findings suggest that the incidence and level of aflatoxins and polycyclic aromatic hydrocarbon exposure was less than that observed in a high-risk population; however, participants consuming higher amounts of foods prone to aflatoxin contamination may be more vulnerable to exposure and interactions with other environmental/biological factors (i.e., hepatitis C virus). |
diet |
1-hydroxypyrene
| Aflatoxin M1
|
Study subjects |
United States |
urine |
1-hydroxypyrene
| Aflatoxin M1
|
Details
|
|
| 41. |
Hofmann JN, et al. (2013).
|
Shanghai Women's Health Study (SWHS) |
In this nested case-control study among participants in the Shanghai Women's Health Study, we did not find evidence of an association between urinary concentration of 1-hydroxypyrene glucuronide, an established marker of polycyclic aromatic hydrocarbon exposure, and risk of colorectal cancer. |
|
1-hydroxypyrene-glucuronide
| Polycyclic Aromatic Hydrocarbons
|
Controls for disease:Colorectal Neoplasms
| Subjects with disease:Colorectal Neoplasms
| Study subjects |
China |
urine |
1-hydroxypyrene-glucuronide
|
Details
|
Colorectal Neoplasms
|
| 42. |
Brody JG, et al. (2009).
|
Northern California Household Exposure Study |
In this study, we found that cumulative air pollution burdens were more pronounced indoors than outdoors in an urban industrial environmental justice community in comparison with a rural community. |
|
1-methylphenanthrene
| 2-methylphenanthrene
| 2-phenylphenol
| acenaphthene
| Aluminum
| Ammonia
| Calcium
| Carbon
| Copper
| Diethylhexyl Phthalate
| dioctyl adipate
| fluoranthene
| fluorene
| Iron
| Lead
| Manganese
| Nitrates
| Particulate Matter
| phenanthrene
| Potassium
| pyrene
| Sulfates
| Vanadium
|
|
United States |
air, indoor | air, outdoor |
1-methylphenanthrene
| 2-methylphenanthrene
| 2-phenylphenol
| acenaphthene
| Aluminum
| Ammonia
| Calcium
| Carbon
| Copper
| Diethylhexyl Phthalate
| dioctyl adipate
| fluoranthene
| fluorene
| Iron
| Lead
| Manganese
| Nitrates
| Particulate Matter
| phenanthrene
| Potassium
| pyrene
| Sulfates
| Vanadium
|
Details
|
|
| 43. |
Jung KH, et al. (2014).
|
Columbia Center for Children's Environmental Health (CCCEH) |
Obese young children may be more likely to develop asthma in association with greater exposure to polycyclic aromatic hydrocarbons, and methylphenanthrenes in particular, than non-obese children. |
body mass index | disease | sex |
1-methylphenanthrene
| 2-methylphenanthrene
| phenanthrene
| pyrene
|
Children | Controls for disease:Obesity
| Subjects with disease:Obesity
|
United States |
air |
1-methylphenanthrene
| 2-methylphenanthrene
| phenanthrene
| pyrene
|
Details
|
Asthma
|
| 44. |
Bradman A, et al. (2003).
|
|
As a first step in validating this (amniotic fluid) exposure biomarker, we collected 100 amniotic fluid samples slated for disposal and evaluated analytical methods to measure organophosphate and carbamate pesticides and metabolites, synthetic pyrethroid metabolites, herbicides, and chlorinated phenolic compounds. |
|
1-naphthol
| 2,5-dichlorophenol
| 2-naphthol
| 2-phenylphenol
| Carbofuran
| diethyl phosphate
| dimethyl phosphate
| O,O-dimethyl phosphorothionate
| Pentachlorophenol
|
Mothers |
United States |
amniotic fluid |
1-naphthol
| 2,5-dichlorophenol
| 2-naphthol
| 2-phenylphenol
| Carbofuran
| diethyl phosphate
| dimethyl phosphate
| O,O-dimethyl phosphorothionate
| Pentachlorophenol
|
Details
|
|
| 45. |
Meeker JD, et al. (2004).
|
|
In the present study we found associations between urinary metabolites of contemporary-use insecticides and decreased sperm concentration and motility in humans. |
|
1-naphthol
| 3,5,6-trichloro-2-pyridinol
| Insecticides
|
Subjects with disease:Infertility, Male
|
United States |
semen | urine |
1-naphthol
| 3,5,6-trichloro-2-pyridinol
|
Details
|
Infertility, Male
| spermatogenesis
| sperm motility
|
| 46. |
Nøst TH, et al. (2013).
|
Tromso study |
Our results suggest substantial intraindividual declines in serum concentrations of legacy persistent organic pollutants from 1979 to 2007 in men from Northern Norway. |
|
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,2',3',4'-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| alpha-hexachlorocyclohexane
| beta-hexachlorocyclohexane
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hexachlorocyclohexane
| Hydrocarbons, Chlorinated
| Mirex
| nonachlor
| o,p'-DDT
| oxychlordane
| PCB 180
| Polychlorinated Biphenyls
| Toxaphene
|
Study subjects |
Norway |
serum |
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,2',3',4'-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| alpha-hexachlorocyclohexane
| beta-hexachlorocyclohexane
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hexachlorocyclohexane
| Hydrocarbons, Chlorinated
| Mirex
| nonachlor
| o,p'-DDT
| oxychlordane
| PCB 180
| Polychlorinated Biphenyls
| Toxaphene
|
Details
|
|
| 47. |
Eskenazi B, et al. (2018).
|
Venda Health Examination of Mothers, Babies and the Environment (VHEMBE) Study |
Prenatal exposure to pyrethroids may be associated at 1 y of age with poorer social-emotional development. At 2 y of age, poorer language development was observed with higher prenatal pyrethroid levels. |
|
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
| 3-phenoxybenzoic acid
| DDT
| Dichlorodiphenyl Dichloroethylene
| o,p'-DDT
| Pyrethrins
|
Children | Pregnant females |
South Africa |
serum | urine |
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
| 3-phenoxybenzoic acid
| DDT
| Dichlorodiphenyl Dichloroethylene
| o,p'-DDT
| Pyrethrins
|
Details
|
cognition
| motor behavior
| social behavior
|
| 48. |
Bouwman H, et al. (2006).
|
|
DDT and pyrethroid insecticides were determined in breast milk from primiparous and multiparous mothers living in three towns in South Africa (one of which had no need for DDT for malaria control); the source of water (river vs. piped) affected some levels in one town. |
|
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
| DDT
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Insecticides
| Mitotane
| o,p'-DDT
|
Mothers |
South Africa |
milk, human |
2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene
| cyfluthrin
| cypermethrin
| DDT
| decamethrin
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Mitotane
| o,p'-DDT
| Permethrin
| Pyrethrins
|
Details
|
|
| 49. |
Watkins DJ, et al. (2011).
|
|
Our research suggests that exposure to pentaBDE (sum of brominated diphenyl ether congeners 28/33, 47, 99, 100, and 153) in the office environment contributes to pentaBDE body burden, with exposure likely linked to polybrominated diphenyl ether residues on hands. |
|
2,2',3,3',4,4',5,5',6-nonabromodiphenyl ether
| 2,2',3,3',4,4',5,6,6'-nonabromodiphenyl ether
| 2,2',3,3',4,4',6,6'-octabromodiphenyl ether
| 2,2',3,3',4,5,5',6,6'-nonabromodiphenyl ether
| 2,2',3,4,4',5',6-heptabromodiphenyl ether
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,2',4,5'-tetrabromodiphenyl ether
| decabromobiphenyl ether
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| hexabromodiphenyl ether 154
| pentabrominated diphenyl ether 100
| pentabromodiphenyl ether
| tribromodiphenyl ether 28
|
Workers |
United States |
dust | handwipe | serum |
2,2',3,3',4,4',5,5',6-nonabromodiphenyl ether
| 2,2',3,3',4,4',5,6,6'-nonabromodiphenyl ether
| 2,2',3,3',4,4',6,6'-octabromodiphenyl ether
| 2,2',3,3',4,5,5',6,6'-nonabromodiphenyl ether
| 2,2',3,4,4',5',6-heptabromodiphenyl ether
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,2',4,5'-tetrabromodiphenyl ether
| decabromobiphenyl ether
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| hexabromodiphenyl ether 154
| pentabrominated diphenyl ether 100
| pentabromodiphenyl ether
| tribromodiphenyl ether 28
|
Details
|
|
| 50. |
Allen JG, et al. (2008).
|
|
Our study presents the first systematic examination of the variation of polybrominated diphenyl ether concentrations in dust within homes and over time. |
|
2,2',3,3',4,4',5,5',6-nonabromodiphenyl ether
| 2,2',3,3',4,4',5,6,6'-nonabromodiphenyl ether
| 2,2',3,3',4,4',6,6'-octabromodiphenyl ether
| 2,2',3,3',4,5,5',6,6'-nonabromodiphenyl ether
| 2,2',3,4,4',5',6-heptabromodiphenyl ether
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,2',4,5'-tetrabromodiphenyl ether
| decabromobiphenyl ether
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| hexabromodiphenyl ether 154
| pentabrominated diphenyl ether 100
| tribromodiphenyl ether 28
|
|
United States |
|
2,2',3,3',4,4',5,5',6-nonabromodiphenyl ether
| 2,2',3,3',4,4',5,6,6'-nonabromodiphenyl ether
| 2,2',3,3',4,4',6,6'-octabromodiphenyl ether
| 2,2',3,3',4,5,5',6,6'-nonabromodiphenyl ether
| 2,2',3,4,4',5',6-heptabromodiphenyl ether
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,2',4,5'-tetrabromodiphenyl ether
| decabromobiphenyl ether
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| hexabromodiphenyl ether 154
| pentabrominated diphenyl ether 100
| tribromodiphenyl ether 28
|
Details
|
|
Illuminating how chemicals affect human health.
Organic Chemicals