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Chemical Pancreatic Polypeptide

Name Pancreatic Polypeptide
Equivalent Terms Pancreatic Polypeptide Hormone | Pancreatic Polypeptide (PP) | Pancreatic Prohormone
CAS Registry Number 59763-91-6
Definition A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D010191
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Top ↑ Ancestors

1. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Pancreatic Hormones Has associated genes Has associated diseases Has associated exposure references Pancreatic Polypeptide
2. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Neuropeptides Has associated genes Has associated diseases Pancreatic Polypeptide
3. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Pancreatic Hormones Has associated genes Has associated diseases Has associated exposure references Pancreatic Polypeptide

Top ↑ Descendants

Pancreatic Polypeptide
  gut PLY, Torpedo marmorata
  pancreatic eicosapeptide
  pancreatic polypeptide (31-36)
  pancreatic polypeptide, avian
  pancreatic polypeptide, salmon
  PP 1420
  PPY2 protein, human
  PPY protein, human
  skin peptide tyrosine-tyrosine