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Chemical Peptides

These are exposure studies associated with the chemical and all of its children.

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1–12 of 12 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Turyk ME, et al. (2007). National Health and Nutrition Examination Survey (NHANES) In the adult participants of NHANES from 1999 to 2002, total thyroxine was negatively associated with serum dioxin-like toxic equivalents in a dose-dependent fashion, with stronger associations in women than men. age | sex 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3,4,7,8-pentachlorodibenzofuran | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Benzofurans | dibenzodioxin | Dichlorodiphenyl Dichloroethylene | Dioxins and Dioxin-like Compounds | Hydrocarbons, Chlorinated | PCB 180 | Polychlorinated Biphenyls Study subjects United States serum 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3,4,7,8-pentachlorodibenzofuran | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Benzofurans | dibenzodioxin | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
2. Herbstman JB, et al. (2008). Prenatal polychlorinated biphenyls (PCBs) and poly-brominated diphenyl ether (PBDE) exposures were associated with reduced total thyroxine and free thyroxine levels among infants born by spontaneous, unassisted vaginal delivery. Intrapartum stress associated with delivery mode may mask hormonal effects of PCBs and PBDEs. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Halogenated Diphenyl Ethers | PCB 180 | pentabromodiphenyl ether | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Infants or newborns United States blood | blood, cord 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | PCB 180 | pentabromodiphenyl ether | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
3. Turyk ME, et al. (2008). Consortium for the health assessment of Great Lakes sport fish consumption Polychlorinated biphenyls exposure, at levels comparable with those of the general U.S. population, was associated with increased thyroglobulin antibodies and increased T(4) in adult males. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls Study subjects United States serum | urine 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls | SERPINA7 | Testosterone | Thyrotropin | Thyroxine | Triiodothyronine Details immunoglobulin production | testosterone biosynthetic process | thyroid hormone metabolic process
4. Solfrizzi V, et al. (2013). Italian Longitudinal Study on Aging (ILSA) Using a large, population-based cohort, we investigated whether angiotensin-converting enzyme inhibitors collectively as a 'class' and as sub-groups according to their chemical structures and drug potencies, compared with other antihypertensive agents and beyond the natural course in time of the hypertension, reduced the incidence of mild cognitive impairment in cognitively normal individuals. Angiotensin-Converting Enzyme Inhibitors | Enalapril | Lisinopril Subjects with disease:Hypertension Italy Details Cognitive Dysfunction
5. Wallin M, et al. (2013). This study provides support for an association between kidney Cadmium levels and urinary calcium excretion in women, but not in men. Cadmium Study subjects Sweden kidney | serum | urine Cadmium | Calcifediol | Calcitriol | Calcium | Parathyroid Hormone Details calcium ion homeostasis
6. Tornhammar P, et al. (2014). Our objective was to assess the link between season of birth, neonatal 25-hydroxyvitamin D3, and adult cardiovascular disease; we report higher neonatal 25(OH)D3 associated with higher levels of cholesterol (in women), fasting insulin, and triglyceride, and with a higher risk of overweight at 35 years of age, but not with other adult cardiovascular disease risk factors. sex Calcifediol | Vitamin D Infants or newborns | Study subjects Sweden blood | serum Calcifediol | Cholesterol | Insulin | Triglycerides Details Obesity | Weight Gain | cholesterol homeostasis | regulation of insulin secretion | triglyceride homeostasis
7. Wang Y, et al. (2013). Norwegian Mother and Child Cohort Study (MoBa) Our results suggest an association between perfluorooctane sulfonate and thyroid stimulating hormone in pregnant women that is small and may be of no clinical significance. Fluorocarbons | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Sulfonic Acids Pregnant females Norway plasma perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | perfluoroundecanoic acid | Sulfonic Acids | Thyrotropin Details thyroid hormone metabolic process
8. Preston EV, et al. (2018). Project Viva In this study, prenatal exposure to some per- and polyfluoroalkyl substances during early pregnancy was inversely associated with maternal free thyroxine (T4) index and neonatal T4 in male infants. Fluorocarbons | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Infants or newborns | Pregnant females United States plasma perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
9. Webster GM, et al. (2016). National Health and Nutrition Examination Survey (NHANES) We found evidence of perfluoroalkyl acids-associated thyroid disruption in a subset of U.S. adults with high thyroid peroxidase antibody (a marker of autoimmune hypothyroidism) and low iodine status, who may represent a vulnerable subgroup. sex hexadecafluoro-nonanoic acid | Iodine | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum | urine hexadecafluoro-nonanoic acid | Iodine | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Thyrotropin | Thyroxine | Triiodothyronine Details thyroid hormone metabolic process
10. Horton MK, et al. (2015). Endocrine Disruption in Pregnant Women: Thyroid Disruption and Infant Development Study Co-exposure to perchlorate, nitrate and thiocyanate may alter maternal thyroid function, specifically thyroid stimulating hormone, during pregnancy. Iodides | Nitrates | perchlorate | thiocyanate Pregnant females United States serum | urine Iodides | Nitrates | perchlorate | thiocyanate | Thyrotropin | Thyroxine Details thyroid-stimulating hormone secretion
11. Keegan TJ, et al. (2009). In the present study, we confirmed for the first time the presence of microcystins in serum samples of fishermen who were chronically exposed to cyanotoxins by oral route. Microcystins Workers China serum Microcystins Details Liver Diseases
12. Johns LE, et al. (2016). LifeCodes Prospective Birth Cohort Overall, the results from our analyses support previous reports showing the potential for environmental phthalate exposure to disturb circulating levels of thyroid hormones in pregnant women. mono-(2-ethylhexyl)phthalate | monoethyl phthalate | phthalic acid Pregnant females United States plasma | urine Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid | Thyroid Hormones | Thyrotropin | Thyroxine | Triiodothyronine Details thyroid hormone metabolic process
1–12 of 12 results.