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Chemical Phenytoin

Name Phenytoin
CAS Type 1 Name 2,4-Imidazolidinedione, 5,5-diphenyl-
Equivalent Terms 5,5-Diphenylhydantoin | Antisacer | Difenin | Dihydan | Dilantin | Diphenylhydantoin | Diphenylhydantoinate, Sodium | Epamin | Epanutin | Fenitoin | Hydantol | Park Davis brand of Phenytoin | Pfizer Brand of Phenytoin | Phenytoin Pfizer Brand | Phenytoin Phizer Brand | Phenytoin Sodium | Phizer Brand of Phenytoin | Sodium Diphenylhydantoinate
CAS Registry Number 57-41-0
Definition An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
Structure Phenytoin
Top Interacting
Genes
MeSH® ID D010672
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Azoles Has associated genes Has associated diseases Has associated exposure references Imidazoles Has associated genes Has associated diseases Has associated exposure references Imidazolidines Has associated genes Has associated diseases Has associated exposure references Hydantoins Has associated genes Has associated diseases Has associated exposure references Phenytoin Has associated genes Has associated diseases

Top ↑ Descendants

Phenytoin Has associated genes Has associated diseases
  1-acetyl-3-acetoxy-5',5-diphenylhydantoin
  2-cyanoguanidinophenytoin
  3-(2-propylpentanoyl)-5,5-diphenylhydantoin
  3-(hydroxymethyl)phenytoin Has associated genes
  3-(hydroxymethyl)phenytoin N,N-dimethylaminoethyl carbonate
  3-hydroxymethylphenytoin N,N-dimethylglycine ester
  3-pentanoyl-5,5-diphenylhydantoin
  4-aminophenytoin
  5-(2-hydroxyphenyl)-5-phenylhydantoin
  5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin
  5-(3,4-dihydroxyphenyl)-5-phenylhydantoin
  5-(3-hydroxyphenyl)-5-phenylhydantoin
  5-(4'-fluorophenyl)-5-phenylhydantoin
  5-(4-hydroxy-3-methoxyphenyl)-5-phenylhydantoin
  5,5-bis(4-hydroxyphenyl)hydantoin
  5,5-diphenyl-2-thiohydantoin-N10
  5,5-diphenylhydantoin-3-valerate-bovine serum albumin
  5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide Has associated genes Has associated diseases
  5-p-methylphenyl-5-phenylhydantoin Has associated genes Has associated diseases
  diphenylhydantil
  diphenylhydantoic acid
  diphenylhydantoin-3-phenyltricarbonylchromium ethyl acetate
  diphenylthiohydantoin
  fosphenytoin Has associated diseases
  Hydanphene
  hydroxyphenytoin Has associated genes Has associated diseases
  mephobarbital, phenobarbital, phenytoin drug combination
  N'-3-oxymethylglucuronide phenytoin
  N-acetylphenytoin
  N-aminodiphenylhydantoin
  N,N-dichlorophenytoin
  PC-796
  phenrytmat
  phenytoin-1-methylnicotininate
  phenytoin-bis-hydroxyisobutyrate
  phenytoin dihydrodiol
  ropitoin hydrochloride
  Sendai cocktail