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Chemical Piperidones

1–50 of 447 results.
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1. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid results in decreased cell growth 1: Homo sapiens Brain | Cell Line, Tumor   1
2. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth TP53 [TP53 protein results in increased susceptibility to 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid] which results in decreased cell growth 1: Homo sapiens HCT116 Cells   1
3. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid results in decreased cell growth 1: Homo sapiens HCT116 Cells   1
4. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth TP53 [TP53 protein results in increased susceptibility to 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid] promotes the reaction [2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid results in decreased cell growth] 1: Homo sapiens Brain | Cell Line, Tumor   1
5. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth TP53 TP53 protein affects the reaction [2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid results in decreased cell growth] 1: Homo sapiens HCT116 Cells   1
6. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid results in decreased cell growth 1: Homo sapiens Brain | Tumor Cells, Cultured   1
7. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid cell growth TP53 [TP53 protein results in increased susceptibility to 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid] promotes the reaction [2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid results in decreased cell growth] 1: Homo sapiens Brain | Tumor Cells, Cultured   1
8. 3,5-bis(2-fluorobenzylidene)piperidin-4-one negative regulation of NF-kappaB transcription factor activity 3,5-bis(2-fluorobenzylidene)piperidin-4-one affects negative regulation of NF-kappaB transcription factor activity  
4 genes: IRAK1 | IRAK2 | NFKBIA | NLRP12
1
9. 3,5-bis(2-fluorobenzylidene)piperidin-4-one positive regulation of interleukin-8 secretion Lipopolysaccharides 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Lipopolysaccharides affects positive regulation of interleukin-8 secretion] 1: Homo sapiens Granulocytes | Cells, Cultured
3 genes: F2R | TLR1 | TLR2
1
10. 3,5-bis(2-fluorobenzylidene)piperidin-4-one cellular response to hypoxia Oxygen 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency affects cellular response to hypoxia] 1: Homo sapiens MCF-7 Cells
8 genes: AKT1 | AQP1 | BCL2L1 | CFLAR | HIF1A | HMOX1 | IRAK1 | SRC
1
11. 3,5-bis(2-fluorobenzylidene)piperidin-4-one cellular response to ionizing radiation 3,5-bis(2-fluorobenzylidene)piperidin-4-one affects cellular response to ionizing radiation 1: Homo sapiens MCF-7 Cells   1
12. 3,5-bis(2-fluorobenzylidene)piperidin-4-one negative regulation of I-kappaB kinase/NF-kappaB signaling 3,5-bis(2-fluorobenzylidene)piperidin-4-one affects negative regulation of I-kappaB kinase/NF-kappaB signaling 1: Homo sapiens MCF-7 Cells
4 genes: CASP8 | NLRP12 | RHOA | RIPK1
1
13. 3,5-bis(2-fluorobenzylidene)piperidin-4-one negative regulation of NF-kappaB transcription factor activity 3,5-bis(2-fluorobenzylidene)piperidin-4-one affects negative regulation of NF-kappaB transcription factor activity 1: Homo sapiens MCF-7 Cells
4 genes: IRAK1 | IRAK2 | NFKBIA | NLRP12
1
14. 3,5-bis(2-fluorobenzylidene)piperidin-4-one positive regulation of cell death Oxygen [3,5-bis(2-fluorobenzylidene)piperidin-4-one co-treated with Oxygen deficiency] affects positive regulation of cell death 1: Homo sapiens MCF-7 Cells
2 genes: NOD1 | RIPK1
1
15. 3,5-bis(2-fluorobenzylidene)piperidin-4-one positive regulation of I-kappaB phosphorylation Oxygen 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency affects positive regulation of I-kappaB phosphorylation] 1: Homo sapiens MCF-7 Cells 1 gene: AKT1 1
16. 3,5-bis(2-fluorobenzylidene)piperidin-4-one positive regulation of NIK/NF-kappaB signaling Oxygen 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency affects positive regulation of NIK/NF-kappaB signaling] 1: Homo sapiens MCF-7 Cells
10 genes: IL12B | MYD88 | NLRP12 | NOD1 | REL | RELA | RHOA | TLR2 | TNF | TNFSF14
1
17. 3,5-bis(2-fluorobenzylidene)piperidin-4-one cell proliferation 3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
8 genes: AKT1 | BCL2L1 | HMGA2 | IL12A | IL12B | SRC | STAT3 | TNF
1
18. 3,5-bis(2-fluorobenzylidene)piperidin-4-one wound healing 3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased wound healing 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: AQP1 | MAP3K1 | VIM
1
19. 3,5-bis(2-fluorobenzylidene)piperidin-4-one wound healing HMGA2 HMGA2 protein inhibits the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased wound healing] 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: AQP1 | MAP3K1 | VIM
1
20. 3,5-bis(2-fluorobenzylidene)piperidin-4-one epithelial to mesenchymal transition 3,5-bis(2-fluorobenzylidene)piperidin-4-one results in increased epithelial to mesenchymal transition 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: HIF1A | HMGA2 | STAT3
1
21. 3,5-bis(2-fluorobenzylidene)piperidin-4-one epithelial to mesenchymal transition MIR33B MIR33B mRNA affects the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in increased epithelial to mesenchymal transition] 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: HIF1A | HMGA2 | STAT3
1
22. 3,5-bis(2-fluorobenzylidene)piperidin-4-one epithelial to mesenchymal transition HMGA2 HMGA2 protein inhibits the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in increased epithelial to mesenchymal transition] 1: Homo sapiens Skin | Cell Line, Tumor
3 genes: HIF1A | HMGA2 | STAT3
1
23. 3,5-bis(2-fluorobenzylidene)piperidin-4-one stress fiber assembly 3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased stress fiber assembly 1: Homo sapiens Skin | Cell Line, Tumor
2 genes: RHOA | SRC
1
24. 3,5-bis(2-fluorobenzylidene)piperidin-4-one stress fiber assembly HMGA2 HMGA2 protein inhibits the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased stress fiber assembly] 1: Homo sapiens Skin | Cell Line, Tumor
2 genes: RHOA | SRC
1
25. 3,5-bis(2-fluorobenzylidene)piperidin-4-one stress fiber assembly MIR33B MIR33B mRNA affects the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased stress fiber assembly] 1: Homo sapiens Skin | Cell Line, Tumor
2 genes: RHOA | SRC
1
26. 3,5-bis(2-fluorobenzylidene)piperidin-4-one focal adhesion assembly 3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased focal adhesion assembly 1: Homo sapiens Skin | Cell Line, Tumor   1
27. 3,5-bis(2-fluorobenzylidene)piperidin-4-one focal adhesion assembly MIR33B MIR33B mRNA affects the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased focal adhesion assembly] 1: Homo sapiens Skin | Cell Line, Tumor   1
28. 3,5-bis(2-fluorobenzylidene)piperidin-4-one focal adhesion assembly HMGA2 HMGA2 protein inhibits the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one results in decreased focal adhesion assembly] 1: Homo sapiens Skin | Cell Line, Tumor   1
29. 4-amino-1,8-naphthalimide G2 DNA damage checkpoint Arsenic Trioxide 4-amino-1,8-naphthalimide inhibits the reaction [Arsenic Trioxide results in increased G2 DNA damage checkpoint] 1: Homo sapiens Hep G2 Cells   1
30. 4-amino-1,8-naphthalimide positive regulation of DNA repair 4-amino-1,8-naphthalimide results in decreased positive regulation of DNA repair 1: Homo sapiens Hep G2 Cells   1
31. 4-amino-1,8-naphthalimide positive regulation of apoptotic process Arsenic Trioxide 4-amino-1,8-naphthalimide promotes the reaction [Arsenic Trioxide results in increased positive regulation of apoptotic process] 1: Homo sapiens Hep G2 Cells
6 genes: ATM | BAX | CASP3 | NOS2 | PRKDC | RELA
1
32. 4-amino-1,8-naphthalimide cell proliferation Arsenic Trioxide 4-amino-1,8-naphthalimide promotes the reaction [Arsenic Trioxide results in decreased cell proliferation] 1: Homo sapiens Hep G2 Cells
4 genes: BAX | BCL2 | PRKDC | XRCC5
1
33. 4-amino-1,8-naphthalimide cell proliferation Arsenic Trioxide | Lipopolysaccharides Lipopolysaccharides inhibits the reaction [4-amino-1,8-naphthalimide promotes the reaction [Arsenic Trioxide results in decreased cell proliferation]] 1: Homo sapiens Hep G2 Cells
4 genes: BAX | BCL2 | PRKDC | XRCC5
1
34. 4-amino-1,8-naphthalimide apoptotic process Arsenic Trioxide 4-amino-1,8-naphthalimide promotes the reaction [Arsenic Trioxide results in increased apoptotic process] 1: Homo sapiens Hep G2 Cells
6 genes: ATM | BAX | BCL2 | CASP3 | CHEK2 | PARP1
1
35. 4-amino-1,8-naphthalimide apoptotic process Arsenic Trioxide | Lipopolysaccharides Lipopolysaccharides inhibits the reaction [4-amino-1,8-naphthalimide promotes the reaction [Arsenic Trioxide results in increased apoptotic process]] 1: Homo sapiens Hep G2 Cells
6 genes: ATM | BAX | BCL2 | CASP3 | CHEK2 | PARP1
1
36. 5-hydroxythalidomide drug metabolic process Thalidomide [Thalidomide results in increased drug metabolic process] which results in increased chemical synthesis of 5-hydroxythalidomide 1: Homo sapiens Placenta | Cell Line, Tumor
2 genes: CYP2C19 | CYP3A4
1
37. Aminoglutethimide positive regulation of apoptotic process Hydrogen Peroxide Hydrogen Peroxide promotes the reaction [Aminoglutethimide results in increased positive regulation of apoptotic process] 1: Homo sapiens HL-60 Cells 1 gene: UBC 1
38. Aminoglutethimide positive regulation of necrotic cell death Aminoglutethimide results in increased positive regulation of necrotic cell death 1: Homo sapiens HL-60 Cells   1
39. Aminoglutethimide positive regulation of apoptotic process 4-aminobenzhydrazide 4-aminobenzhydrazide inhibits the reaction [Aminoglutethimide results in increased positive regulation of apoptotic process] 1: Homo sapiens HL-60 Cells 1 gene: UBC 1
40. Aminoglutethimide positive regulation of necrotic cell death 4-aminobenzhydrazide 4-aminobenzhydrazide inhibits the reaction [Aminoglutethimide results in increased positive regulation of necrotic cell death] 1: Homo sapiens HL-60 Cells   1
41. Aminoglutethimide protein oxidation Hydrogen Peroxide [Aminoglutethimide co-treated with Hydrogen Peroxide] results in increased protein oxidation 1: Homo sapiens HL-60 Cells 1 gene: GPX1 1
42. Aminoglutethimide progesterone biosynthetic process Aminoglutethimide results in decreased progesterone biosynthetic process 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
2 genes: FSHB | LHB
1
43. Aminoglutethimide progesterone biosynthetic process Progesterone [Aminoglutethimide results in decreased progesterone biosynthetic process] which results in decreased abundance of Progesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
2 genes: FSHB | LHB
1
44. Aminoglutethimide testosterone biosynthetic process Aminoglutethimide results in decreased testosterone biosynthetic process 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
4 genes: CYP11A1 | CYP19A1 | HSD17B1 | STAR
1
45. Aminoglutethimide testosterone biosynthetic process Testosterone [Aminoglutethimide results in decreased testosterone biosynthetic process] which results in decreased abundance of Testosterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
4 genes: CYP11A1 | CYP19A1 | HSD17B1 | STAR
1
46. Aminoglutethimide positive regulation of estrogen biosynthetic process Aminoglutethimide results in decreased positive regulation of estrogen biosynthetic process 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
47. Aminoglutethimide positive regulation of estrogen biosynthetic process Estradiol [Aminoglutethimide results in decreased positive regulation of estrogen biosynthetic process] which results in decreased abundance of Estradiol 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
48. Aminoglutethimide testosterone biosynthetic process Colforsin Aminoglutethimide inhibits the reaction [Colforsin results in increased testosterone biosynthetic process] 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
4 genes: CYP11A1 | CYP19A1 | HSD17B1 | STAR
1
49. Aminoglutethimide testosterone biosynthetic process Colforsin | Testosterone Aminoglutethimide inhibits the reaction [[Colforsin results in increased testosterone biosynthetic process] which results in increased abundance of Testosterone] 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
4 genes: CYP11A1 | CYP19A1 | HSD17B1 | STAR
1
50. Aminoglutethimide positive regulation of estrogen biosynthetic process Colforsin Aminoglutethimide inhibits the reaction [Colforsin results in increased positive regulation of estrogen biosynthetic process] 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
1–50 of 447 results.