| 1. |
Sexton K, et al. (2007).
|
|
Our aim was to compare and rank relative health risks of 179 air pollutants in Houston using an evidence-based approach supplemented by the expert judgment of a panel of academic scientists. |
|
1,1,2,2-tetrachloroethane
| 1,3-butadiene
| 1,6-hexamethylene diisocyanate
| Acetaldehyde
| Acrolein
| acrylic acid
| Acrylonitrile
| Arsenicals
| Benzene
| Carbon Tetrachloride
| Chlorine
| chromium hexavalent ion
| Ethylene Dibromide
| ethylene dichloride
| Ethylene Oxide
| Formaldehyde
| naphthalene
| Ozone
| Particulate Matter
| Vehicle Emissions
| Vinyl Chloride
|
Study subjects |
United States |
|
|
Details
|
Disorders of Environmental Origin
| Neoplasms
|
| 2. |
Loh MM, et al. (2007).
|
|
In this study we compared cancer risks from organic hazardous air pollutants (HAPs) based on total personal exposure summed across different microenvironments and exposure pathways. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1,3-dichloro-1-propene
| 4-dichlorobenzene
| Acetaldehyde
| anthracene
| benz(a)anthracene
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| Carbon Tetrachloride
| Chloroform
| chrysene
| Dioxins
| Ethylene Dibromide
| ethylene dichloride
| fluoranthene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Methylene Chloride
| naphthalene
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Study subjects |
United States |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1,3-dichloro-1-propene
| 4-dichlorobenzene
| Acetaldehyde
| anthracene
| benz(a)anthracene
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| Carbon Tetrachloride
| Chloroform
| chrysene
| Dioxins
| Ethylene Dibromide
| ethylene dichloride
| fluoranthene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Methylene Chloride
| naphthalene
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Details
|
Neoplasms
|
| 3. |
Aquilina NJ, et al. (2010).
|
Measurement and Modelling of Air Toxic Concentrations for Health Effect Studies Project (MATCH) |
The objective of this study was to analyse environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbon (PAH) metabolites in urine samples of non-occupationally exposed non-smoker adult subjects and to establish relationships between airborne exposures and urinary concentrations in order to assess the suitability of the studied metabolites as biomarkers of PAH and ETS, study the use of 3-ethenypyridine as ETS tracer, and link ETS scenarios with exposures to carcinogenic PAH and volatile organic compounds. |
tobacco |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-vinylpyridine
| acenaphthene
| acenaphthylene
| anthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| coronene
| fluoranthene
| fluorene
| hydroxycotinine
| indeno(1,2,3-cd)pyrene
| naphthalene
| Nicotine
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Study subjects |
United Kingdom |
urine |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-vinylpyridine
| acenaphthene
| acenaphthylene
| anthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| coronene
| fluoranthene
| fluorene
| hydroxycotinine
| indeno(1,2,3-cd)pyrene
| naphthalene
| Nicotine
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Details
|
|
| 4. |
von Ehrenstein OS, et al. (2016).
|
California Cancer Registry |
Our data suggest that in utero and infancy exposures to air toxics generated by industrial and road traffic sources may increase the risk of primitive neuroectodermal tumor and medulloblastoma, with limited support for increased risks for astrocytoma in children up to age 6. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 2-dichlorobenzene
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| Chloroform
| Chromium
| chromium hexavalent ion
| ethylbenzene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Lead
| Methylene Chloride
| Nickel
| Polycyclic Aromatic Hydrocarbons
| Selenium
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Study subjects |
United States |
air |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 2-dichlorobenzene
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| Chloroform
| Chromium
| chromium hexavalent ion
| ethylbenzene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Lead
| Methylene Chloride
| Nickel
| Polycyclic Aromatic Hydrocarbons
| Selenium
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Details
|
Astrocytoma
| Medulloblastoma
| Neuroectodermal Tumors, Primitive
|
| 5. |
Choi H, et al. (2008).
|
|
Prenatal polycyclic aromatic hydrocarbon exposure is likely to contribute to the occurrence of small size for gestational age as well as preterm births among African Americans. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
|
Pregnant females |
United States |
air |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
|
Details
|
Fetal Growth Retardation
| Premature Birth
| Prenatal Exposure Delayed Effects
|
| 6. |
Tonne CC, et al. (2004).
|
|
In this study, we examined levels of exposures to polycyclic aromatic hydrocarbons and tested for associations with potential predictor variables collected from questionnaires addressing socioeconomic factors and day-to-day activities during pregnancy as well as activities and environmental exposures during the 48-hr monitoring period. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Pregnant females |
Croatia|France|
Italy|United States |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Details
|
|
| 7. |
Varlet V, et al. (2015).
|
|
We analyzed 42 models from 14 brands of refill liquids for e-cigarettes for the presence of micro-organisms, diethylene glycol, ethylene glycol, hydrocarbons, ethanol, aldehydes, tobacco-specific nitrosamines, and solvents. |
|
1,1-diethoxyethane
| 1,3-butadiene
| 1-Butanol
| 1-Propanol
| 2-butenal
| 2-methylbenzaldehyde
| 3-methylbenzaldehyde
| 4-cymene
| 4-methylbenzaldehyde
| Acetaldehyde
| Acetoin
| Acetone
| Acrolein
| alpha-pinene
| benzaldehyde
| beta-pinene
| butyraldehyde
| Cyclohexane
| Diacetyl
| diethylene glycol
| Ethanol
| ethyl acetate
| Ethylene Glycol
| ethyl propionate
| Formaldehyde
| gamma-terpinene
| Hydrocarbons
| isobutyl acetate
| isovalerylaldehyde
| Limonene
| n-hexanal
| Nitrosamines
| pentanal
| propionaldehyde
|
|
Switzerland |
e-cigarette, liquid |
1,1-diethoxyethane
| 1,3-butadiene
| 1-Butanol
| 1-Propanol
| 2-butenal
| 2-methylbenzaldehyde
| 3-methylbenzaldehyde
| 4-cymene
| 4-methylbenzaldehyde
| Acetaldehyde
| Acetoin
| Acetone
| Acrolein
| alpha-pinene
| benzaldehyde
| beta-pinene
| butyraldehyde
| Cyclohexane
| Diacetyl
| diethylene glycol
| Ethanol
| ethyl acetate
| Ethylene Glycol
| ethyl propionate
| Formaldehyde
| gamma-terpinene
| Hydrocarbons
| isobutyl acetate
| isovalerylaldehyde
| Limonene
| n-hexanal
| Nitrosamines
| pentanal
| propionaldehyde
|
Details
|
|
| 8. |
Dodson RE, et al. (2015).
|
California Household Exposure Study (CAHES) |
We collected house dust and indoor air samples in 49 California homes and analyzed for 76 semivolatile organic compounds-phthalates, polybrominated diphenyl ethers, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, and pesticides. |
|
1,2,5,6-dibenzanthracene
| 1-methylphenanthrene
| 1-nitropyrene
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| 2-methylphenanthrene
| 2-phenylphenol
| 4,6-dimethyldibenzothiophene
| 4-nitrotoluene
| acenaphthene
| acenaphthylene
| alachlor
| Aldrin
| anthracene
| Atrazine
| bendiocarb
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(j)fluoranthene
| benzo(k)fluoranthene
| benzothiophene
| butylbenzyl phthalate
| Carbaryl
| Carbofuran
| Chlordan
| Chlorpyrifos
| chrysene
| cyanazine
| cypermethrin
| DDT
| Diazinon
| dibenzo(a,e)pyrene
| dibenzothiophene
| Dibutyl Phthalate
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Dicofol
| dicyclohexyl phthalate
| Dieldrin
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| di-n-hexyl phthalate
| di-n-octyl phthalate
| di-n-pentyl phthalate
| di-n-propylphthalate
| dioctyl adipate
| Endrin
| fluoranthene
| fluorene
| Heptachlor
| Hexachlorocyclohexane
| indeno(1,2,3-cd)pyrene
| Malathion
| Methoxychlor
| Methyl Parathion
| metolachlor
| nitrofen
| Parathion
| pentabrominated diphenyl ether 100
| Permethrin
| phenanthrene
| Phenanthrenes
| Piperonyl Butoxide
| prometone
| Propoxur
| pyrene
| Simazine
| tetrachloroisophthalonitrile
| Trifluralin
| tris(2,3-dibromopropyl)phosphate
|
|
United States |
dust |
1,2,5,6-dibenzanthracene
| 1-methylphenanthrene
| 1-nitropyrene
| 2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| 2-methylphenanthrene
| 2-phenylphenol
| 4,6-dimethyldibenzothiophene
| 4-nitrotoluene
| acenaphthene
| acenaphthylene
| alachlor
| Aldrin
| anthracene
| Atrazine
| bendiocarb
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(j)fluoranthene
| benzo(k)fluoranthene
| benzothiophene
| butylbenzyl phthalate
| Carbaryl
| Carbofuran
| Chlordan
| Chlorpyrifos
| chrysene
| cyanazine
| cypermethrin
| DDT
| Diazinon
| dibenzo(a,e)pyrene
| dibenzothiophene
| Dibutyl Phthalate
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Dicofol
| dicyclohexyl phthalate
| Dieldrin
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| di-n-hexyl phthalate
| di-n-octyl phthalate
| di-n-pentyl phthalate
| di-n-propylphthalate
| dioctyl adipate
| Endrin
| fluoranthene
| fluorene
| Heptachlor
| Hexachlorocyclohexane
| indeno(1,2,3-cd)pyrene
| Malathion
| Methoxychlor
| Methyl Parathion
| metolachlor
| nitrofen
| Parathion
| pentabrominated diphenyl ether 100
| Permethrin
| phenanthrene
| Phenanthrenes
| Piperonyl Butoxide
| prometone
| Propoxur
| pyrene
| Simazine
| tetrachloroisophthalonitrile
| Trifluralin
| tris(2,3-dibromopropyl)phosphate
|
Details
|
|
| 9. |
Goniewicz ML, et al. (2018).
|
Population Assessment of Tobacco and Health (PATH) Study |
These findings provide evidence that using combusted tobacco cigarettes alone or in combination with e-cigarettes is associated with higher concentrations of potentially harmful tobacco constituents in comparison with using e-cigarettes alone. |
tobacco |
1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-butenal
| 2-hydroxyfluorene
| 2-naphthol
| 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol
| Acrolein
| Acrylamide
| Acrylonitrile
| Anabasine
| anatabine
| Arsenic
| Benzene
| Beryllium
| Cadmium
| Carbon Disulfide
| Cobalt
| Cotinine
| cotinine-N-oxide
| Dimethylformamide
| ethylbenzene
| Ethylene Oxide
| Fluorenes
| hydroxycotinine
| Isocyanates
| isoprene
| Lead
| mandelic acid
| Manganese
| nicotine 1-N-oxide
| Nicotine
| N'-nitrosoanabasine
| N'-nitrosoanatabine
| N'-nitrosonornicotine
| norcotinine
| nornicotine
| Phenanthrenes
| propylene oxide
| Strontium
| Styrene
| Thallium
| Toluene
| Uranium
| Vinyl Chloride
| Xylenes
|
Study subjects |
United States |
urine |
1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-butenal
| 2-hydroxyfluorene
| 2-methylhippuric acid
| 2-naphthol
| 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol
| Acrolein
| Acrylamide
| Acrylonitrile
| Anabasine
| anatabine
| Arsenic
| Benzene
| Beryllium
| Cadmium
| Carbon Disulfide
| Cobalt
| Cotinine
| cotinine-N-oxide
| Dimethylformamide
| Fluorenes
| Hippurates
| hydroxycotinine
| isoprene
| Lead
| mandelic acid
| Manganese
| N-acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
| N-acetyl-S-(2-cyanoethyl)cysteine
| N-acetyl-S-(2-hydroxyethyl)cysteine
| nicotine 1-N-oxide
| Nicotine
| N'-nitrosoanabasine
| N'-nitrosoanatabine
| N'-nitrosonornicotine
| norcotinine
| nornicotine
| Phenanthrenes
| phenylglyoxylic acid
| propylene oxide
| S-(3-hydroxypropyl)cysteine N-acetate
| S-benzyl-N-acetyl-L-cysteine
| Strontium
| Thallium
| Uranium
|
Details
|
|
| 10. |
Goniewicz ML, et al. (2017).
|
|
This study showed for the first time that after switching from tobacco to e-cigarettes, nicotine exposure remains unchanged, while exposure to selected carcinogens and toxicants is substantially reduced. |
tobacco |
1,3-butadiene
| 2-butenal
| 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
| Acrolein
| Acrylamide
| Acrylonitrile
| Benzene
| Carbon Monoxide
| Ethylene Oxide
| fluorene
| naphthalene
| Nicotine
| phenanthrene
| propylene oxide
| pyrene
|
Study subjects |
Poland |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-hydroxy-1-methylpropylmercapturic acid
| 4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol
| Acetylcysteine
| Carbon Monoxide
| Cotinine
| cotinine-N-oxide
| fluorene
| hydroxycotinine
| N-acetyl-S-(2-hydroxyethyl)cysteine
| nicotine 1-N-oxide
| Nicotine
| norcotinine
| nornicotine
| phenanthrene
| S-phenyl-N-acetylcysteine
|
Details
|
|
| 11. |
Rull RP, et al. (2006).
|
|
Data on two case-control study populations of infants with neural tube defects (NTDs) and nonmalformed controls delivered in California between 1987 and 1991 were pooled to investigate whether maternal residential proximity to applications of specific pesticides or physicochemical groups of pesticides during early gestation increases the risk of these malformations. |
|
1,3-dichloro-1-propene
| Amides
| Benomyl
| Benzimidazoles
| Captan
| Chlorpyrifos
| devrinol
| Dimethoate
| Disulfoton
| Methomyl
| methyl carbamate
| methyl demeton
| Naled
| Organophosphorus Compounds
| vendex
|
Infants or newborns |
United States |
|
1,3-dichloro-1-propene
| Amides
| Benomyl
| Benzimidazoles
| Captan
| Chlorpyrifos
| devrinol
| Dimethoate
| Disulfoton
| Methomyl
| methyl carbamate
| methyl demeton
| Naled
| Organophosphorus Compounds
| vendex
|
Details
|
Anencephaly
| Neural Tube Defects
| Spinal Dysraphism
|
| 12. |
Kponee KZ, et al. (2018).
|
|
In this pilot study, we measured indoor volatile organic compound (VOC) concentrations in the indoor air of 20 households in Ogale, an Ogoniland community whose groundwater system is contaminated with benzene at levels 900 times the World Health Organization guidelines and evaluated self-reported health conditions and predicted cancer risks and hazards from inhalation exposure to VOCs. |
|
1,4-dioxane
| 2,5-dimethylfuran
| 2-xylene
| 3-xylene
| 4-cymene
| 4-dichlorobenzene
| 4-xylene
| Benzene
| Carbon Tetrachloride
| cumene
| ethylbenzene
| hemimellitene
| Limonene
| mesitylene
| naphthalene
| n-propylbenzene
| pseudocumene
| sec-butylbenzene
| Styrene
| Toluene
| Xylenes
|
Study subjects |
Nigeria |
air |
1,4-dioxane
| 2,5-dimethylfuran
| 2-xylene
| 3-xylene
| 4-cymene
| 4-dichlorobenzene
| 4-xylene
| Benzene
| Carbon Tetrachloride
| cumene
| ethylbenzene
| hemimellitene
| Limonene
| mesitylene
| naphthalene
| n-propylbenzene
| pseudocumene
| sec-butylbenzene
| Styrene
| Toluene
| Xylenes
|
Details
|
Neoplasms
|
| 13. |
Pronk A, et al. (2006).
|
|
The aim of this study was to assess which compounds contribute to isocyanate exposure in car body repair shops and industrial painting companies, and to identify tasks with a high risk of isocyanate exposure. |
|
1,6-hexamethyleneaminoisocyanate
| 1,6-hexamethylene diisocyanate
| 2,6-diisocyanatotoluene
| 4,4'-diphenylmethane diisocyanate
| Biuret
| ethyl isocyanate
| Isocyanates
| isophorone diisocyanate
| methyl isocyanate
| phenyl isocyanate
| Toluene 2,4-Diisocyanate
|
Workers |
Netherlands |
|
1,6-hexamethyleneaminoisocyanate
| 1,6-hexamethylene diisocyanate
| 2,6-diisocyanatotoluene
| 4,4'-diphenylmethane diisocyanate
| Biuret
| ethyl isocyanate
| Isocyanates
| isophorone diisocyanate
| methyl isocyanate
| phenyl isocyanate
| Toluene 2,4-Diisocyanate
|
Details
|
|
| 14. |
Deng Q, et al. (2014).
|
Coke-oven Workers (COW) Cohort |
We identified five potentially polycyclic aromatic hydrocarbon (PAH)-associated miRNAs in plasma, and the same miRNAs were associated with a marker of chromosome damage in coke oven workers, suggesting that miRNAs might be a novel mechanism mediating the effects of PAH exposure on chromosome damage. |
alcohol drinking |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Workers |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
miRNA metabolic process
|
| 15. |
Li J, et al. (2018).
|
Coke-oven Workers (COW) Cohort | Shiyan (SY) Cohort | Wuhan-Zhuhai (WHZH) Cohort |
Our findings suggest that exposure to polycyclic aromatic hydrocarbons may be associated with an adverse impact on human aging and epigenetic alterations in Chinese populations. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Study subjects |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
aging
| DNA methylation
|
| 16. |
Yang B, et al. (2016).
|
|
Our results indicated polycyclic aromatic hydrocarbons exposure was associated with plasma cytokines, and higher cytokines were associated with decreased heart rate variability, but additional human and potential mechanistic studies are needed. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Workers |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| ALCAM
| BDNF
| CRP
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
Cardiovascular Diseases
| gene expression
|
| 17. |
Li Z, et al. (2012).
|
|
This study aimed to investigate the excretion half-life of 1-hydroxypyrene (1-PYR), the most used biomarker for polycyclic aromatic hydrocarbon (PAH) exposure, and 9 other mono-hydroxylated metabolites following a dietary exposure in 9 non-smoking volunteers with no occupational exposure to PAHs. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
|
Study subjects |
United States |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
|
Details
|
|
| 18. |
Barraza-Villarreal A, et al. (2014).
|
|
Biomarkers of polycyclic aromatic hydrocarbons exposure were inversely associated with lung function and decrease of pH of exhaled breath condensate as a marker of airway inflammation in Mexican schoolchildren. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Children |
Mexico |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| fluoren-9-ol
| Fluorenes
| Phenanthrenes
|
Details
|
respiratory system process
|
| 19. |
Zhou Y, et al. (2016).
|
Wuhan-Zhuhai (WHZH) Cohort |
Total and specific urinary polycyclic aromatic hydrocarbons metabolites were associated with lung function reduction in a general Chinese population. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Study subjects |
China |
urine |
Polycyclic Aromatic Hydrocarbons
|
Details
|
respiratory system process
|
| 20. |
Tuakuila J, et al. (2013).
|
|
This study reveals the high pyrene (PAH) exposure of the Kinshasa population requiring the determination of PAH concentrations in ambient air of Kinshasa and limits values for the protection of human health. |
tobacco |
1-hydroxypyrene
|
Study subjects |
Congo, the Democratic Republic of the |
urine |
1-hydroxypyrene
|
Details
|
|
| 21. |
Ji G, et al. (2010).
|
Nanjing Medical University Infertile Study |
These findings provided the first evidence that polymorphisms of XRCC1 may modify sperm Polycyclic Aromatic Hydrocarbons-DNA adduct levels and may be useful biomarkers to identify individuals susceptible to DNA damage resulting from PAHs exposure. |
genetics |
1-hydroxypyrene
|
Subjects with disease:Infertility, Male
|
China |
urine |
1-hydroxypyrene
|
Details
|
Infertility, Male
|
| 22. |
Trejo-Acevedo A, et al. (2012).
|
|
The aim of this study was to evaluate the exposure levels to persistent organic pollutants and 1-hydroxypyrene in children living in an endemic malaria zone in Mexico. |
|
1-hydroxypyrene
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',3,4',5,5',6-heptachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,2',3',4'-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Aldrin
| alpha-hexachlorocyclohexane
| beta-hexachlorocyclohexane
| Chlordan
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hexachlorocyclohexane
| Mirex
| nonachlor
| PCB 180
| Polychlorinated Biphenyls
|
Children |
Mexico |
plasma | urine |
1-hydroxypyrene
| 2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',3,4',5,5',6-heptachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3,4,2',3',4'-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Aldrin
| alpha-hexachlorocyclohexane
| beta-hexachlorocyclohexane
| Chlordan
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hexachlorocyclohexane
| Mirex
| nonachlor
| PCB 180
| Polychlorinated Biphenyls
|
Details
|
|
| 23. |
Woodruff TJ, et al. (2011).
|
National Health and Nutrition Examination Survey (NHANES) |
Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. |
|
1-hydroxypyrene
| 2,2',4,4',5,5'-hexabrominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2-naphthol
| 4-dichlorobenzene
| Benzene
| bisphenol A
| Cadmium
| Cotinine
| DDT
| Dichlorodiphenyl Dichloroethylene
| diethyl phosphate
| dimethyl phosphate
| fluoren-9-ol
| Hexachlorobenzene
| Lead
| Mercury
| methyl tert-butyl ether
| mono-benzyl phthalate
| monobutyl phthalate
| mono-isobutyl phthalate
| O,O-dimethyl phosphorodithioate
| O,O-dimethyl phosphorothionate
| oxybenzone
| PCB 180
| perchlorate
| perfluorooctane sulfonic acid
| perfluorooctanoic acid
| thiophosphoric acid
| Toluene
| Triclosan
|
Pregnant females | Study subjects |
United States |
blood | serum | urine |
1-hydroxypyrene
| 2,2',4,4',5,5'-hexabrominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2-naphthol
| 4-dichlorobenzene
| Benzene
| bisphenol A
| Cadmium
| Cotinine
| DDT
| Dichlorodiphenyl Dichloroethylene
| diethyl phosphate
| dimethyl phosphate
| fluoren-9-ol
| Hexachlorobenzene
| Lead
| Mercury
| methyl tert-butyl ether
| mono-benzyl phthalate
| monobutyl phthalate
| mono-isobutyl phthalate
| O,O-dimethyl phosphorodithioate
| O,O-dimethyl phosphorothionate
| oxybenzone
| PCB 180
| perchlorate
| perfluorooctane sulfonic acid
| perfluorooctanoic acid
| thiophosphoric acid
| Toluene
| Triclosan
|
Details
|
|
| 24. |
Johnson NM, et al. (2010).
|
|
Findings suggest that the incidence and level of aflatoxins and polycyclic aromatic hydrocarbon exposure was less than that observed in a high-risk population; however, participants consuming higher amounts of foods prone to aflatoxin contamination may be more vulnerable to exposure and interactions with other environmental/biological factors (i.e., hepatitis C virus). |
diet |
1-hydroxypyrene
| Aflatoxin M1
|
Study subjects |
United States |
urine |
1-hydroxypyrene
| Aflatoxin M1
|
Details
|
|
| 25. |
Hofmann JN, et al. (2013).
|
Shanghai Women's Health Study (SWHS) |
In this nested case-control study among participants in the Shanghai Women's Health Study, we did not find evidence of an association between urinary concentration of 1-hydroxypyrene glucuronide, an established marker of polycyclic aromatic hydrocarbon exposure, and risk of colorectal cancer. |
|
1-hydroxypyrene-glucuronide
| Polycyclic Aromatic Hydrocarbons
|
Controls for disease:Colorectal Neoplasms
| Subjects with disease:Colorectal Neoplasms
| Study subjects |
China |
urine |
1-hydroxypyrene-glucuronide
|
Details
|
Colorectal Neoplasms
|
| 26. |
Brody JG, et al. (2009).
|
Northern California Household Exposure Study |
In this study, we found that cumulative air pollution burdens were more pronounced indoors than outdoors in an urban industrial environmental justice community in comparison with a rural community. |
|
1-methylphenanthrene
| 2-methylphenanthrene
| 2-phenylphenol
| acenaphthene
| Aluminum
| Ammonia
| Calcium
| Carbon
| Copper
| Diethylhexyl Phthalate
| dioctyl adipate
| fluoranthene
| fluorene
| Iron
| Lead
| Manganese
| Nitrates
| Particulate Matter
| phenanthrene
| Potassium
| pyrene
| Sulfates
| Vanadium
|
|
United States |
air, indoor | air, outdoor |
1-methylphenanthrene
| 2-methylphenanthrene
| 2-phenylphenol
| acenaphthene
| Aluminum
| Ammonia
| Calcium
| Carbon
| Copper
| Diethylhexyl Phthalate
| dioctyl adipate
| fluoranthene
| fluorene
| Iron
| Lead
| Manganese
| Nitrates
| Particulate Matter
| phenanthrene
| Potassium
| pyrene
| Sulfates
| Vanadium
|
Details
|
|
| 27. |
Jung KH, et al. (2014).
|
Columbia Center for Children's Environmental Health (CCCEH) |
Obese young children may be more likely to develop asthma in association with greater exposure to polycyclic aromatic hydrocarbons, and methylphenanthrenes in particular, than non-obese children. |
body mass index | disease | sex |
1-methylphenanthrene
| 2-methylphenanthrene
| phenanthrene
| pyrene
|
Children | Controls for disease:Obesity
| Subjects with disease:Obesity
|
United States |
air |
1-methylphenanthrene
| 2-methylphenanthrene
| phenanthrene
| pyrene
|
Details
|
Asthma
|
| 28. |
Bradman A, et al. (2003).
|
|
As a first step in validating this (amniotic fluid) exposure biomarker, we collected 100 amniotic fluid samples slated for disposal and evaluated analytical methods to measure organophosphate and carbamate pesticides and metabolites, synthetic pyrethroid metabolites, herbicides, and chlorinated phenolic compounds. |
|
1-naphthol
| 2,5-dichlorophenol
| 2-naphthol
| 2-phenylphenol
| Carbofuran
| diethyl phosphate
| dimethyl phosphate
| O,O-dimethyl phosphorothionate
| Pentachlorophenol
|
Mothers |
United States |
amniotic fluid |
1-naphthol
| 2,5-dichlorophenol
| 2-naphthol
| 2-phenylphenol
| Carbofuran
| diethyl phosphate
| dimethyl phosphate
| O,O-dimethyl phosphorothionate
| Pentachlorophenol
|
Details
|
|
| 29. |
Meeker JD, et al. (2004).
|
|
In the present study we found associations between urinary metabolites of contemporary-use insecticides and decreased sperm concentration and motility in humans. |
|
1-naphthol
| 3,5,6-trichloro-2-pyridinol
| Insecticides
|
Subjects with disease:Infertility, Male
|
United States |
semen | urine |
1-naphthol
| 3,5,6-trichloro-2-pyridinol
|
Details
|
Infertility, Male
| spermatogenesis
| sperm motility
|
| 30. |
Ayotte P, et al. (2005).
|
|
In summary, we found no relation between biomarkers of organochlorine exposure and markers of hepatic enzyme induction in this highly exposed group of fish eaters from the Lower North Shore of the St. Lawrence River. Our results suggest that smoking induces liver CYP1A2 activity, which in turn alters porphyrin metabolism and increases the biotransformation of mono-ortho polychlorinated biphenyls. |
tobacco |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hydrocarbons, Chlorinated
| Mirex
| nonachlor
| oxychlordane
| PCB 180
| Polychlorinated Biphenyls
|
Study subjects |
Canada |
plasma | urine |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Coproporphyrins
| Dichlorodiphenyl Dichloroethylene
| Glucaric Acid
| Hexachlorobenzene
| Hydrocarbons, Chlorinated
| Mirex
| nonachlor
| oxychlordane
| PCB 180
| Polychlorinated Biphenyls
| Uroporphyrins
|
Details
|
enzyme activator activity
|
| 31. |
Vested A, et al. (2014).
|
|
The objective of this study was to investigate whether maternal serum concentrations of polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) during pregnancy are associated with son's semen quality and reproductive hormone levels. |
|
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Dichlorodiphenyl Dichloroethylene
| PCB 180
| Polychlorinated Biphenyls
|
Mothers | Study subjects |
Denmark |
semen | serum |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Dichlorodiphenyl Dichloroethylene
| Estradiol
| FSHB
| INHBB
| LHB
| PCB 180
| SHBG
| Testosterone
|
Details
|
spermatogenesis
| sperm motility
|
| 32. |
Patel CJ, et al. (2012).
|
National Health and Nutrition Examination Survey (NHANES) |
We screened for correlation between environmental factors and lipid levels, utilizing four independent surveys with information on 188 environmental factors from the Centers of Disease Control, National Health and Nutrition Examination Survey, collected between 1999 and 2006. |
age | body mass index | race | sex | socioeconomic status |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,3-bis(3'-hydroxybenzyl)butyrolactone
| 2,4,4',5-tetrachlorobiphenyl
| 2-hydroxyfluorene
| alpha-Tocopherol
| Ascorbic Acid
| beta Carotene
| Cotinine
| Cryptoxanthins
| Fluorenes
| Folic Acid
| gamma-Tocopherol
| Heptachlor Epoxide
| Iron
| Lycopene
| Mercury
| nonachlor
| oxychlordane
| retinol palmitate
| retinyl stearate
| Vitamin A
| Vitamin D
|
Study subjects |
United States |
|
|
Details
|
cholesterol metabolic process
| triglyceride metabolic process
|
| 33. |
Chevrier J, et al. (2007).
|
Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) |
In summary, we report a positive association between neonatal thyroid-stimulating hormone levels and prenatal exposure to polychlorinated biphenyls (PCBs) reported to induce microsomal enzymes (specifically CYP2B) and suspected to induce uridinediphosphate glucuronosyltransferase in animals but not with the sum of all PCB congeners, or PCBs grouped according to their dioxin-like activity or structure. |
|
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4',5-tetrachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| PCB 180
| Polycyclic Aromatic Hydrocarbons
|
Pregnant females |
United States |
serum |
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4',5-tetrachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| PCB 180
| Polycyclic Aromatic Hydrocarbons
|
Details
|
hormone metabolic process
|
| 34. |
Gagnon F, et al. (2004).
|
|
A survey was carried out on 162 recreational harvesters, and shellfish were sampled for chemical contaminant analysis. |
|
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Arsenic
| benzo(e)pyrene
| Cadmium
| Chlordan
| Chromium
| Copper
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Lead
| Manganese
| Mercury
| naphthalene
| Nickel
| nonachlor
| Polychlorinated Biphenyls
| Selenium
| Zinc
|
Workers |
Canada |
|
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Arsenic
| benzo(e)pyrene
| Cadmium
| Chlordan
| Chromium
| Copper
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Lead
| Manganese
| Mercury
| naphthalene
| Nickel
| nonachlor
| Polychlorinated Biphenyls
| Selenium
| Zinc
|
Details
|
|
| 35. |
Turyk ME, et al. (2008).
|
Consortium for the health assessment of Great Lakes sport fish consumption |
Polychlorinated biphenyls exposure, at levels comparable with those of the general U.S. population, was associated with increased thyroglobulin antibodies and increased T(4) in adult males. |
|
2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| Dichlorodiphenyl Dichloroethylene
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| pentabrominated diphenyl ether 100
| Polychlorinated Biphenyls
|
Study subjects |
United States |
serum | urine |
2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| Dichlorodiphenyl Dichloroethylene
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| pentabrominated diphenyl ether 100
| Polychlorinated Biphenyls
| SERPINA7
| Testosterone
| Thyrotropin
| Thyroxine
| Triiodothyronine
|
Details
|
immunoglobulin production
| testosterone biosynthetic process
| thyroid hormone metabolic process
|
| 36. |
Johansson GM, et al. (2015).
|
|
This first study of amine adducts in hairdressers and consumers identified an increase in o- and m-toluidine Hb-adduct concentrations among hairdressers, associated with the weekly number of hair dye and hair waving treatments performed. |
|
2,3-didehydro-5-O-mycaminosyl-23-O-acetyltylonolide
| 2-toluidine
| 3-toluidine
| 4-toluidine
|
Study subjects | Workers |
Sweden |
blood |
2,3-didehydro-5-O-mycaminosyl-23-O-acetyltylonolide
| 2-toluidine
| 3-toluidine
| 4-toluidine
|
Details
|
|
| 37. |
Goldner WS, et al. (2010).
|
Agricultural Health Study (AHS) |
These data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study. |
|
2,4,5-Trichlorophenoxyacetic Acid
| 2,4-Dichlorophenoxyacetic Acid
| alachlor
| Aldrin
| Atrazine
| Benomyl
| butylate
| Captan
| Carbaryl
| Carbon Disulfide
| Carbon Tetrachloride
| Chlordan
| chlorimuron ethyl
| Chlorpyrifos
| cyanazine
| DDT
| Diazinon
| Dicamba
| Dichlorvos
| EPTC
| Fonofos
| Fungicides, Industrial
| glyphosate
| Heptachlor
| Hexachlorocyclohexane
| Hydrocarbons, Chlorinated
| imazethapyr
| Insecticides
| Malathion
| mancozeb
| Maneb
| metalaxyl
| methyl bromide
| metolachlor
| metribuzin
| Paraquat
| Parathion
| pendimethalin
| Petroleum
| terbufos
| tetrachloroisophthalonitrile
| Trifluralin
|
Study subjects |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Hyperthyroidism
| Hypothyroidism
|
| 38. |
Hoppin JA, et al. (2007).
|
Agricultural Health Study (AHS) |
These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence. |
|
2,4,5-Trichlorophenoxyacetic Acid
| Carbaryl
| Carbofuran
| chlorimuron ethyl
| DDT
| Diazinon
| Dichlorvos
| fenoprop
| Heptachlor
| Malathion
| Permethrin
|
Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Bronchitis, Chronic
|
| 39. |
Koutros S, et al. (2011).
|
Agricultural Health Study (AHS) |
We evaluated pesticide-single nucleotide polymorphism (SNP) interactions between 45 pesticides and 1913 xenobiotic metabolic enzyme SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study. |
genetics |
2,4,5-Trichlorophenoxyacetic Acid
| Carbaryl
| Diazinon
| Dieldrin
| Fonofos
| Hexachlorocyclohexane
| methyl bromide
| Petroleum
| Phorate
| terbufos
|
Subjects with gene influence:GCLC
| Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Prostatic Neoplasms
|
| 40. |
Hoppin JA, et al. (2017).
|
Agricultural Health Study (AHS) |
We evaluated the association of currently used pesticides with allergic and non-allergic wheeze among male farmers, and our results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects. |
|
2,4-Dichlorophenoxyacetic Acid
| acetochlor
| Atrazine
| bentazone
| Carbaryl
| Chlorpyrifos
| clomazone
| clopyralid
| cyfluthrin
| Dicamba
| Dimethoate
| Disulfoton
| fenoxaprop ethyl
| fluazifop-butyl
| glyphosate
| Herbicides
| imazaquin
| Insecticides
| Malathion
| mesotrione
| metolachlor
| N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide
| nicosulfuron
| Permethrin
| Petroleum
| Picloram
| Pyrethrins
| Rodenticides
| Simazine
| triclopyr
| Trifluralin
| Warfarin
|
Workers |
United States |
|
|
Details
|
Respiratory Sounds
| Rhinitis, Allergic
|
| 41. |
Hoppin JA, et al. (2002).
|
Agricultural Health Study (AHS) |
Prevalence of wheeze was associated with individual pesticides independent of animals, crops, and grains. |
disease |
2,4-Dichlorophenoxyacetic Acid
| alachlor
| Aldicarb
| aluminum phosphide
| Atrazine
| Benomyl
| butylate
| Captan
| Carbaryl
| Carbofuran
| chlorimuron ethyl
| Chlorpyrifos
| Coumaphos
| cyanazine
| Diazinon
| Dicamba
| Dichlorvos
| EPTC
| Fonofos
| glyphosate
| Hexachlorocyclohexane
| imazethapyr
| Malathion
| Maneb
| metalaxyl
| metolachlor
| metribuzin
| Paraquat
| Parathion
| pendimethalin
| Permethrin
| Petroleum
| Phorate
| terbufos
| tetrachloroisophthalonitrile
| Trichlorfon
| Trifluralin
| Ziram
|
Subjects with disease:Asthma
| Subjects with disease:Ige Responsiveness, Atopic
| Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Respiratory Sounds
|
| 42. |
Lee WJ, et al. (2007).
|
Agricultural Health Study (AHS) |
This explorative study suggests an association between the incidence of colorectal cancer and use of certain pesticides, in particularly chlorpyrifos and aldicarb, although some findings could be due to chance. |
age | body mass index | tobacco |
2,4-Dichlorophenoxyacetic Acid
| Aldicarb
| Carbaryl
| Chlorpyrifos
| Fonofos
| Toxaphene
|
Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Colorectal Neoplasms
| Rectal Neoplasms
|
| 43. |
Hoppin JA, et al. (2008).
|
Agricultural Health Study (AHS) |
These findings suggest that pesticides may contribute to atopic asthma, but not nonatopic asthma, among farm women. |
|
2,4-Dichlorophenoxyacetic Acid
| Carbamates
| Carbaryl
| Coumaphos
| DDT
| glyphosate
| Hydrocarbons, Chlorinated
| Malathion
| metalaxyl
| Organophosphates
| Parathion
| Permethrin
| Pesticides
| Phorate
|
Study subjects |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Asthma
|
| 44. |
Meng JE, et al. (2012).
|
Osteoporosis and Periodontal Disease (OsteoPerio) Study | Women's Health Initiative (WHI) Observational Study |
We investigated the intraindividual variability between two measures of plasma 25(OH)D concentrations collected 5 years apart (1997-2000 to 2002-2005) in 672 postmenopausal women participating in the Women's Health Initiative. |
|
25-hydroxyvitamin D
|
Study subjects |
United States |
plasma |
25-hydroxyvitamin D
|
Details
|
|
| 45. |
Sonderman JS, et al. (2012).
|
Southern Community Cohort Study (SCCS) |
The present findings suggest that single, prediagnostic measurements of serum 25(OH)D and vitamin D-binding protein levels provide a reasonably representative baseline measure of these compounds for both white and black adults, demonstrating their utility as epidemiologic biomarkers in prospective studies. |
|
25-hydroxyvitamin D
|
Study subjects |
United States |
serum |
25-hydroxyvitamin D
|
Details
|
|
| 46. |
Palacios C, et al. (2012).
|
|
In this group of overweight and obese individuals, 25-Hydroxyvitamin D was significantly related to vitamin D intake, sun exposure and vitamin D intake indices and percent body fat. |
body mass index | diet |
25-hydroxyvitamin D
| Vitamin D
|
Study subjects |
Puerto Rico |
serum |
25-hydroxyvitamin D
| Vitamin D
|
Details
|
|
| 47. |
Ferguson KK, et al. (2014).
|
Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) |
We explored the relationship of prenatal and childhood exposures to phthalates and bisphenol A with pubertal onset and sex hormones in boys (ages 8-14); prenatal exposure was associated with decreased dehydroepiandrosterone sulfate, decreased inhibin B, increased SHBG, greatly reduced odds of adrenarche, and slightly reduced odds of puberty, while childhood exposure was not associated with adrenarche or puberty, but some exposures were associated with increased SHBG levels and decreased testosterone levels. |
age | sex |
2-ethyl-5-carboxypentyl phthalate
| bisphenol A
| mono(2-ethyl-5-hydroxyhexyl) phthalate
| mono(2-ethyl-5-oxohexyl)phthalate
| mono-(2-ethylhexyl)phthalate
| mono-benzyl phthalate
| monobutyl phthalate
| monoethyl phthalate
| mono-isobutyl phthalate
| Phthalic Acids
|
Children | Fetuses | Pregnant females |
Mexico |
serum | urine |
2-ethyl-5-carboxypentyl phthalate
| bisphenol A
| Dehydroepiandrosterone Sulfate
| INHBB
| mono(2-ethyl-5-hydroxyhexyl) phthalate
| mono(2-ethyl-5-oxohexyl)phthalate
| mono-(2-ethylhexyl)phthalate
| mono-benzyl phthalate
| monobutyl phthalate
| monoethyl phthalate
| mono-isobutyl phthalate
| SHBG
| Testosterone
|
Details
|
dehydroepiandrosterone secretion
| development of secondary male sexual characteristics
| inhibin secretion
| testosterone secretion
|
| 48. |
Kioumourtzoglou MA, et al. (2013).
|
Aerosol Research and Inhalation Epidemiology Study (ARIES) |
Results suggest that week-long exposures to traffic-related, primary organic species are associated with increased rate of total and cause-specific cardiovascular disease emergency hospital admissions. |
|
9-fluorenone
| acenaphthylene
| benzo(b)fluoranthene
| benzo(e)pyrene
| benzo(k)fluoranthene
| chrysene
| Cyclohexane
| cyclopenta(c,d)pyrene
| docosane
| dotriacontane
| fluoranthene
| hentriacontane
| n-heneicosane
| nonacosane
| n-pentacosane
| n-tricosane
| octacosane
| Particulate Matter
| phenanthrene
| pyrene
| retene
| Soot
| tetracosane
| tritriacontane
|
Subjects with disease:Cardiovascular Diseases
| Subjects with disease:Coronary Disease
| Subjects with disease:Myocardial Infarction
| Subjects with disease:Pulmonary Disease, Chronic Obstructive
|
United States |
air |
9-fluorenone
| acenaphthylene
| benzo(b)fluoranthene
| benzo(e)pyrene
| benzo(k)fluoranthene
| chrysene
| Cyclohexane
| cyclopenta(c,d)pyrene
| docosane
| dotriacontane
| fluoranthene
| hentriacontane
| n-heneicosane
| nonacosane
| n-pentacosane
| n-tricosane
| octacosane
| phenanthrene
| pyrene
| retene
| Soot
| tetracosane
| tritriacontane
|
Details
|
Cardiovascular Diseases
| Coronary Disease
| Myocardial Infarction
| Pulmonary Disease, Chronic Obstructive
|
| 49. |
Tayyarah R, et al. (2014).
|
|
The purpose of this study was to determine content and delivery of e-cigarette ingredients and to compare e-cigarette aerosol to conventional cigarettes with respect to select harmful and potentially harmful constituents for which conventional cigarette smoke is routinely tested. |
tobacco |
Acetaldehyde
| Acrolein
| Carbon Monoxide
| Particulate Matter
| Phenol
| Phenols
| Polycyclic Aromatic Hydrocarbons
| propionaldehyde
| Volatile Organic Compounds
|
|
United States |
air | e-cigarette, vapor |
Acetaldehyde
| Acrolein
| Carbon Monoxide
| Nicotine
| Phenol
| Phenols
| Polycyclic Aromatic Hydrocarbons
| propionaldehyde
| Volatile Organic Compounds
|
Details
|
|
| 50. |
Logue JM, et al. (2012).
|
|
The approach demonstrated in this study may be used to assess regional and national initiatives that affect indoor air quality at the population level. Cumulative health impacts from inhalation in U.S. residences of the indoor air pollutants assessed in this study are estimated at 400-1,100 disability-adjusted life years lost annually per 100,000 persons. |
|
Air Pollutants
|
|
United States |
|
1,1,1,2-tetrachloroethane
| 1,1,2-trichloroethane
| 1,3-butadiene
| 2-butenal
| 2-ethoxyethanol
| 2-ethylhexanol
| 2-phenylphenol
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Acrolein
| Acrylonitrile
| Ammonia
| Arsenic
| Atrazine
| Benzaldehydes
| Benzene
| Benzo(a)pyrene
| benzyl chloride
| Beryllium
| bromodichloromethane
| bromoform
| Cadmium
| Carbon Disulfide
| Carbon Monoxide
| Carbon Tetrachloride
| chlorobenzene
| chlorodibromomethane
| Chloroform
| Chromium
| cumene
| Cyclohexane
| Diethylhexyl Phthalate
| dioctyl adipate
| Ethanol
| ethylbenzene
| Ethyl Chloride
| Ethylene Dibromide
| ethylene dichloride
| Formaldehyde
| hexachlorobutadiene
| Manganese
| Mercury
| methyl cellosolve
| Methyl Chloride
| Methylene Chloride
| methylethyl ketone
| methyl isobutyl ketone
| Methylmethacrylate
| methyl tert-butyl ether
| naphthalene
| n-butoxyethanol
| Nitrogen Dioxide
| Ozone
| Particulate Matter
| Pentachlorophenol
| Styrene
| Sulfur Dioxide
| Tetrachloroethylene
| tetrahydrofuran
| Toluene
| Trichloroethylene
| Vinyl Chloride
| vinylidene chloride
| Xylenes
|
Details
|
|
Illuminating how chemicals affect human health.
Polycyclic Compounds