| 1. |
Sexton K, et al. (2007).
|
|
Our aim was to compare and rank relative health risks of 179 air pollutants in Houston using an evidence-based approach supplemented by the expert judgment of a panel of academic scientists. |
|
1,1,2,2-tetrachloroethane
| 1,3-butadiene
| 1,6-hexamethylene diisocyanate
| Acetaldehyde
| Acrolein
| acrylic acid
| Acrylonitrile
| Arsenicals
| Benzene
| Carbon Tetrachloride
| Chlorine
| chromium hexavalent ion
| Ethylene Dibromide
| ethylene dichloride
| Ethylene Oxide
| Formaldehyde
| naphthalene
| Ozone
| Particulate Matter
| Vehicle Emissions
| Vinyl Chloride
|
Study subjects |
United States |
|
|
Details
|
Disorders of Environmental Origin
| Neoplasms
|
| 2. |
Loh MM, et al. (2007).
|
|
In this study we compared cancer risks from organic hazardous air pollutants (HAPs) based on total personal exposure summed across different microenvironments and exposure pathways. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1,3-dichloro-1-propene
| 4-dichlorobenzene
| Acetaldehyde
| anthracene
| benz(a)anthracene
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| Carbon Tetrachloride
| Chloroform
| chrysene
| Dioxins
| Ethylene Dibromide
| ethylene dichloride
| fluoranthene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Methylene Chloride
| naphthalene
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Study subjects |
United States |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1,3-dichloro-1-propene
| 4-dichlorobenzene
| Acetaldehyde
| anthracene
| benz(a)anthracene
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| Carbon Tetrachloride
| Chloroform
| chrysene
| Dioxins
| Ethylene Dibromide
| ethylene dichloride
| fluoranthene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Methylene Chloride
| naphthalene
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Tetrachloroethylene
| Trichloroethylene
| Vinyl Chloride
|
Details
|
Neoplasms
|
| 3. |
Aquilina NJ, et al. (2010).
|
Measurement and Modelling of Air Toxic Concentrations for Health Effect Studies Project (MATCH) |
The objective of this study was to analyse environmental tobacco smoke (ETS) and polycyclic aromatic hydrocarbon (PAH) metabolites in urine samples of non-occupationally exposed non-smoker adult subjects and to establish relationships between airborne exposures and urinary concentrations in order to assess the suitability of the studied metabolites as biomarkers of PAH and ETS, study the use of 3-ethenypyridine as ETS tracer, and link ETS scenarios with exposures to carcinogenic PAH and volatile organic compounds. |
tobacco |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-vinylpyridine
| acenaphthene
| acenaphthylene
| anthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| coronene
| fluoranthene
| fluorene
| hydroxycotinine
| indeno(1,2,3-cd)pyrene
| naphthalene
| Nicotine
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Study subjects |
United Kingdom |
urine |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 2-naphthol
| 3-vinylpyridine
| acenaphthene
| acenaphthylene
| anthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| coronene
| fluoranthene
| fluorene
| hydroxycotinine
| indeno(1,2,3-cd)pyrene
| naphthalene
| Nicotine
| phenanthrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Details
|
|
| 4. |
von Ehrenstein OS, et al. (2016).
|
California Cancer Registry |
Our data suggest that in utero and infancy exposures to air toxics generated by industrial and road traffic sources may increase the risk of primitive neuroectodermal tumor and medulloblastoma, with limited support for increased risks for astrocytoma in children up to age 6. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 2-dichlorobenzene
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| Chloroform
| Chromium
| chromium hexavalent ion
| ethylbenzene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Lead
| Methylene Chloride
| Nickel
| Polycyclic Aromatic Hydrocarbons
| Selenium
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Controls for disease:Neuroectodermal Tumors, Primitive
| Subjects with disease:Neuroectodermal Tumors, Primitive
|
United States |
air |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| 1,3-butadiene
| 2-dichlorobenzene
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Benzene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| Chloroform
| Chromium
| chromium hexavalent ion
| ethylbenzene
| Formaldehyde
| indeno(1,2,3-cd)pyrene
| Lead
| Methylene Chloride
| Nickel
| Polycyclic Aromatic Hydrocarbons
| Selenium
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
|
Details
|
Astrocytoma
| Medulloblastoma
| Neuroectodermal Tumors, Primitive
|
| 5. |
Choi H, et al. (2008).
|
|
Prenatal polycyclic aromatic hydrocarbon exposure is likely to contribute to the occurrence of small size for gestational age as well as preterm births among African Americans. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
|
Pregnant females |
United States |
air |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
|
Details
|
Fetal Growth Retardation
| Premature Birth
| Prenatal Exposure Delayed Effects
|
| 6. |
Tonne CC, et al. (2004).
|
|
In this study, we examined levels of exposures to polycyclic aromatic hydrocarbons and tested for associations with potential predictor variables collected from questionnaires addressing socioeconomic factors and day-to-day activities during pregnancy as well as activities and environmental exposures during the 48-hr monitoring period. |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Pregnant females |
Croatia|France|
Italy|United States |
|
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(k)fluoranthene
| chrysene
| indeno(1,2,3-cd)pyrene
| Polycyclic Aromatic Hydrocarbons
| pyrene
|
Details
|
|
| 7. |
Dodson RE, et al. (2015).
|
California Household Exposure Study (CAHES) |
We collected house dust and indoor air samples in 49 California homes and analyzed for 76 semivolatile organic compounds-phthalates, polybrominated diphenyl ethers, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, and pesticides. |
|
1,2,5,6-dibenzanthracene
| 1-methylphenanthrene
| 1-nitropyrene
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| 2-methylphenanthrene
| 2-phenylphenol
| 4,6-dimethyldibenzothiophene
| 4-nitrotoluene
| acenaphthene
| acenaphthylene
| alachlor
| Aldrin
| anthracene
| Atrazine
| bendiocarb
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(j)fluoranthene
| benzo(k)fluoranthene
| benzothiophene
| butylbenzyl phthalate
| Carbaryl
| Carbofuran
| Chlordan
| Chlorpyrifos
| chrysene
| cyanazine
| cypermethrin
| DDT
| Diazinon
| dibenzo(a,e)pyrene
| dibenzothiophene
| Dibutyl Phthalate
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Dicofol
| dicyclohexyl phthalate
| Dieldrin
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| di-n-hexyl phthalate
| di-n-octyl phthalate
| di-n-pentyl phthalate
| di-n-propylphthalate
| dioctyl adipate
| Endrin
| fluoranthene
| fluorene
| Heptachlor
| indeno(1,2,3-cd)pyrene
| Lindane
| Malathion
| Methoxychlor
| Methyl Parathion
| metolachlor
| nitrofen
| Parathion
| pentabromodiphenyl ether
| Permethrin
| phenanthrene
| Phenanthrenes
| Piperonyl Butoxide
| prometone
| Propoxur
| pyrene
| Simazine
| tetrachloroisophthalonitrile
| Trifluralin
| tris(2,3-dibromopropyl)phosphate
|
|
United States |
dust |
1,2,5,6-dibenzanthracene
| 1-methylphenanthrene
| 1-nitropyrene
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| 2-methylphenanthrene
| 2-phenylphenol
| 4,6-dimethyldibenzothiophene
| 4-nitrotoluene
| acenaphthene
| acenaphthylene
| alachlor
| Aldrin
| anthracene
| Atrazine
| bendiocarb
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(j)fluoranthene
| benzo(k)fluoranthene
| benzothiophene
| butylbenzyl phthalate
| Carbaryl
| Carbofuran
| Chlordan
| Chlorpyrifos
| chrysene
| cyanazine
| cypermethrin
| DDT
| Diazinon
| dibenzo(a,e)pyrene
| dibenzothiophene
| Dibutyl Phthalate
| Dichlorodiphenyldichloroethane
| Dichlorodiphenyl Dichloroethylene
| Dicofol
| dicyclohexyl phthalate
| Dieldrin
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| di-n-hexyl phthalate
| di-n-octyl phthalate
| di-n-pentyl phthalate
| di-n-propylphthalate
| dioctyl adipate
| Endrin
| fluoranthene
| fluorene
| Heptachlor
| indeno(1,2,3-cd)pyrene
| Lindane
| Malathion
| Methoxychlor
| Methyl Parathion
| metolachlor
| nitrofen
| Parathion
| pentabromodiphenyl ether
| Permethrin
| phenanthrene
| Phenanthrenes
| Piperonyl Butoxide
| prometone
| Propoxur
| pyrene
| Simazine
| tetrachloroisophthalonitrile
| Trifluralin
| tris(2,3-dibromopropyl)phosphate
|
Details
|
|
| 8. |
Rull RP, et al. (2006).
|
|
Data on two case-control study populations of infants with neural tube defects (NTDs) and nonmalformed controls delivered in California between 1987 and 1991 were pooled to investigate whether maternal residential proximity to applications of specific pesticides or physicochemical groups of pesticides during early gestation increases the risk of these malformations. |
|
1,3-dichloro-1-propene
| Amides
| Benomyl
| Benzimidazoles
| Captan
| Chlorpyrifos
| devrinol
| Dimethoate
| Disulfoton
| Methomyl
| methyl carbamate
| methyl demeton
| Naled
| Organophosphorus Compounds
| vendex
|
Infants or newborns |
United States |
|
1,3-dichloro-1-propene
| Amides
| Benomyl
| Benzimidazoles
| Captan
| Chlorpyrifos
| devrinol
| Dimethoate
| Disulfoton
| Methomyl
| methyl carbamate
| methyl demeton
| Naled
| Organophosphorus Compounds
| vendex
|
Details
|
Anencephaly
| Neural Tube Defects
| Spinal Dysraphism
|
| 9. |
Pronk A, et al. (2006).
|
|
The aim of this study was to assess which compounds contribute to isocyanate exposure in car body repair shops and industrial painting companies, and to identify tasks with a high risk of isocyanate exposure. |
|
1,6-hexamethyleneaminoisocyanate
| 1,6-hexamethylene diisocyanate
| 2,6-diisocyanatotoluene
| 4,4'-diphenylmethane diisocyanate
| Biuret
| ethyl isocyanate
| Isocyanates
| isophorone diisocyanate
| methyl isocyanate
| phenyl isocyanate
| Toluene 2,4-Diisocyanate
|
Workers |
Netherlands |
|
1,6-hexamethyleneaminoisocyanate
| 1,6-hexamethylene diisocyanate
| 2,6-diisocyanatotoluene
| 4,4'-diphenylmethane diisocyanate
| Biuret
| ethyl isocyanate
| Isocyanates
| isophorone diisocyanate
| methyl isocyanate
| phenyl isocyanate
| Toluene 2,4-Diisocyanate
|
Details
|
|
| 10. |
Yang B, et al. (2016).
|
|
Our results indicated polycyclic aromatic hydrocarbons exposure was associated with plasma cytokines, and higher cytokines were associated with decreased heart rate variability, but additional human and potential mechanistic studies are needed. |
|
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Workers |
China |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| 9-phenanthrol
| ALCAM
| BDNF
| CRP
| fluoren-9-ol
| Phenanthrenes
| Polycyclic Aromatic Hydrocarbons
|
Details
|
Cardiovascular Diseases
| gene expression
|
| 11. |
Tuakuila J, et al. (2013).
|
|
This study reveals the high pyrene (PAH) exposure of the Kinshasa population requiring the determination of PAH concentrations in ambient air of Kinshasa and limits values for the protection of human health. |
tobacco |
1-hydroxypyrene
|
Study subjects |
Congo, the Democratic Republic of the |
urine |
1-hydroxypyrene
|
Details
|
|
| 12. |
Ji G, et al. (2010).
|
Nanjing Medical University Infertile Study |
These findings provided the first evidence that polymorphisms of XRCC1 may modify sperm Polycyclic Aromatic Hydrocarbons-DNA adduct levels and may be useful biomarkers to identify individuals susceptible to DNA damage resulting from PAHs exposure. |
genetics |
1-hydroxypyrene
|
Subjects with disease:Infertility, Male
|
China |
urine |
1-hydroxypyrene
|
Details
|
Infertility, Male
|
| 13. |
Woodruff TJ, et al. (2011).
|
National Health and Nutrition Examination Survey (NHANES) |
Our analysis of the NHANES pregnancy data shows ubiquitous exposure to multiple chemicals during a sensitive period of fetal development. |
|
1-hydroxypyrene
| 2,2',4,4',5,5'-hexabrominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2-naphthol
| 4-dichlorobenzene
| Benzene
| bisphenol A
| Cadmium
| Cotinine
| DDT
| Dichlorodiphenyl Dichloroethylene
| diethyl phosphate
| dimethyl phosphate
| fluoren-9-ol
| Hexachlorobenzene
| Lead
| Mercury
| methyl tert-butyl ether
| mono-benzyl phthalate
| monobutyl phthalate
| mono-isobutyl phthalate
| O,O-dimethyl phosphorodithioate
| O,O-dimethyl phosphorothionate
| oxybenzone
| PCB 180
| perchlorate
| perfluorooctane sulfonic acid
| perfluorooctanoic acid
| thiophosphoric acid
| Toluene
| Triclosan
|
Pregnant females | Study subjects |
United States |
blood | serum | urine |
1-hydroxypyrene
| 2,2',4,4',5,5'-hexabrominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2-naphthol
| 4-dichlorobenzene
| Benzene
| bisphenol A
| Cadmium
| Cotinine
| DDT
| Dichlorodiphenyl Dichloroethylene
| diethyl phosphate
| dimethyl phosphate
| fluoren-9-ol
| Hexachlorobenzene
| Lead
| Mercury
| methyl tert-butyl ether
| mono-benzyl phthalate
| monobutyl phthalate
| mono-isobutyl phthalate
| O,O-dimethyl phosphorodithioate
| O,O-dimethyl phosphorothionate
| oxybenzone
| PCB 180
| perchlorate
| perfluorooctane sulfonic acid
| perfluorooctanoic acid
| thiophosphoric acid
| Toluene
| Triclosan
|
Details
|
|
| 14. |
Johnson NM, et al. (2010).
|
|
Findings suggest that the incidence and level of aflatoxins and polycyclic aromatic hydrocarbon exposure was less than that observed in a high-risk population; however, participants consuming higher amounts of foods prone to aflatoxin contamination may be more vulnerable to exposure and interactions with other environmental/biological factors (i.e., hepatitis C virus). |
diet |
1-hydroxypyrene
| Aflatoxin M1
|
Study subjects |
United States |
urine |
1-hydroxypyrene
| Aflatoxin M1
|
Details
|
|
| 15. |
Brody JG, et al. (2009).
|
Northern California Household Exposure Study |
In this study, we found that cumulative air pollution burdens were more pronounced indoors than outdoors in an urban industrial environmental justice community in comparison with a rural community. |
|
1-methylphenanthrene
| 2-methylphenanthrene
| 2-phenylphenol
| acenaphthene
| Aluminum
| Ammonia
| Calcium
| Carbon
| Copper
| Diethylhexyl Phthalate
| dioctyl adipate
| fluoranthene
| fluorene
| Iron
| Lead
| Manganese
| Nitrates
| Particulate Matter
| phenanthrene
| Potassium
| pyrene
| Sulfates
| Vanadium
|
|
United States |
air, indoor | air, outdoor |
1-methylphenanthrene
| 2-methylphenanthrene
| 2-phenylphenol
| acenaphthene
| Aluminum
| Ammonia
| Calcium
| Carbon
| Copper
| Diethylhexyl Phthalate
| dioctyl adipate
| fluoranthene
| fluorene
| Iron
| Lead
| Manganese
| Nitrates
| Particulate Matter
| phenanthrene
| Potassium
| pyrene
| Sulfates
| Vanadium
|
Details
|
|
| 16. |
Jung KH, et al. (2014).
|
Columbia Center for Children's Environmental Health (CCCEH) |
Obese young children may be more likely to develop asthma in association with greater exposure to polycyclic aromatic hydrocarbons, and methylphenanthrenes in particular, than non-obese children. |
body mass index | disease | sex |
1-methylphenanthrene
| 2-methylphenanthrene
| phenanthrene
| pyrene
|
Children | Controls for disease:Obesity
| Subjects with disease:Obesity
|
United States |
air |
1-methylphenanthrene
| 2-methylphenanthrene
| phenanthrene
| pyrene
|
Details
|
Asthma
|
| 17. |
Bradman A, et al. (2003).
|
|
As a first step in validating this (amniotic fluid) exposure biomarker, we collected 100 amniotic fluid samples slated for disposal and evaluated analytical methods to measure organophosphate and carbamate pesticides and metabolites, synthetic pyrethroid metabolites, herbicides, and chlorinated phenolic compounds. |
|
1-naphthol
| 2,5-dichlorophenol
| 2-naphthol
| 2-phenylphenol
| Carbofuran
| diethyl phosphate
| dimethyl phosphate
| O,O-dimethyl phosphorothionate
| Pentachlorophenol
|
Mothers |
United States |
amniotic fluid |
1-naphthol
| 2,5-dichlorophenol
| 2-naphthol
| 2-phenylphenol
| Carbofuran
| diethyl phosphate
| dimethyl phosphate
| O,O-dimethyl phosphorothionate
| Pentachlorophenol
|
Details
|
|
| 18. |
Meeker JD, et al. (2004).
|
|
In the present study we found associations between urinary metabolites of contemporary-use insecticides and decreased sperm concentration and motility in humans. |
|
1-naphthol
| 3,5,6-trichloro-2-pyridinol
| Insecticides
|
Subjects with disease:Infertility, Male
|
United States |
semen | urine |
1-naphthol
| 3,5,6-trichloro-2-pyridinol
|
Details
|
Infertility, Male
| spermatogenesis
| sperm motility
|
| 19. |
Ayotte P, et al. (2005).
|
|
In summary, we found no relation between biomarkers of organochlorine exposure and markers of hepatic enzyme induction in this highly exposed group of fish eaters from the Lower North Shore of the St. Lawrence River. Our results suggest that smoking induces liver CYP1A2 activity, which in turn alters porphyrin metabolism and increases the biotransformation of mono-ortho polychlorinated biphenyls. |
tobacco |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Hydrocarbons, Chlorinated
| Mirex
| nonachlor
| oxychlordane
| PCB 180
| Polychlorinated Biphenyls
|
Study subjects |
Canada |
plasma | urine |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Coproporphyrins
| Dichlorodiphenyl Dichloroethylene
| Glucaric Acid
| Hexachlorobenzene
| Hydrocarbons, Chlorinated
| Mirex
| nonachlor
| oxychlordane
| PCB 180
| Polychlorinated Biphenyls
| Uroporphyrins
|
Details
|
enzyme activator activity
|
| 20. |
Vested A, et al. (2014).
|
|
The objective of this study was to investigate whether maternal serum concentrations of polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) during pregnancy are associated with son's semen quality and reproductive hormone levels. |
|
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Dichlorodiphenyl Dichloroethylene
| PCB 180
| Polychlorinated Biphenyls
|
Mothers | Study subjects |
Denmark |
semen | serum |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,2',3',4,4',5-hexachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| Dichlorodiphenyl Dichloroethylene
| Estradiol
| FSHB
| INHBB
| LHB
| PCB 180
| SHBG
| Testosterone
|
Details
|
spermatogenesis
| sperm motility
|
| 21. |
Patel CJ, et al. (2012).
|
National Health and Nutrition Examination Survey (NHANES) |
We screened for correlation between environmental factors and lipid levels, utilizing four independent surveys with information on 188 environmental factors from the Centers of Disease Control, National Health and Nutrition Examination Survey, collected between 1999 and 2006. |
age | body mass index | race | sex | socioeconomic status |
2,2',3,3',4,4',5-heptachlorobiphenyl
| 2,3-bis(3'-hydroxybenzyl)butyrolactone
| 2,4,4',5-tetrachlorobiphenyl
| 2-hydroxyfluorene
| alpha-Tocopherol
| Ascorbic Acid
| beta Carotene
| Cotinine
| Cryptoxanthins
| Fluorenes
| Folic Acid
| gamma-Tocopherol
| Heptachlor Epoxide
| Iron
| lycopene
| Mercury
| nonachlor
| oxychlordane
| retinol palmitate
| retinyl stearate
| Vitamin A
| Vitamin D
|
Study subjects |
United States |
|
|
Details
|
cholesterol metabolic process
| triglyceride metabolic process
|
| 22. |
Chevrier J, et al. (2007).
|
Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) |
In summary, we report a positive association between neonatal thyroid-stimulating hormone levels and prenatal exposure to polychlorinated biphenyls (PCBs) reported to induce microsomal enzymes (specifically CYP2B) and suspected to induce uridinediphosphate glucuronosyltransferase in animals but not with the sum of all PCB congeners, or PCBs grouped according to their dioxin-like activity or structure. |
|
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4',5-tetrachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| PCB 180
| Polycyclic Aromatic Hydrocarbons
|
Pregnant females |
United States |
serum |
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4',5-hexachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,4',5-tetrachlorobiphenyl
| 2,4,4'-trichlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| PCB 180
| Polycyclic Aromatic Hydrocarbons
|
Details
|
hormone metabolic process
|
| 23. |
Gagnon F, et al. (2004).
|
|
A survey was carried out on 162 recreational harvesters, and shellfish were sampled for chemical contaminant analysis. |
|
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Arsenic
| benzo(e)pyrene
| Cadmium
| Chlordan
| Chromium
| Copper
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Lead
| Manganese
| Mercury
| naphthalene
| Nickel
| nonachlor
| Polychlorinated Biphenyls
| Selenium
| Zinc
|
Workers |
Canada |
|
2,2',3',4,4',5-hexachlorobiphenyl
| 2,2',4,4',5-pentachlorobiphenyl
| 2,3,3',4,4'-pentachlorobiphenyl
| 2,3',4,4',5-pentachlorobiphenyl
| 2,4,5,2',4',5'-hexachlorobiphenyl
| 2,4,5,2',5'-pentachlorobiphenyl
| 2,5,2',5'-tetrachlorobiphenyl
| Arsenic
| benzo(e)pyrene
| Cadmium
| Chlordan
| Chromium
| Copper
| DDT
| Dichlorodiphenyl Dichloroethylene
| Hexachlorobenzene
| Lead
| Manganese
| Mercury
| naphthalene
| Nickel
| nonachlor
| Polychlorinated Biphenyls
| Selenium
| Zinc
|
Details
|
|
| 24. |
Turyk ME, et al. (2008).
|
Consortium for the health assessment of Great Lakes sport fish consumption |
Polychlorinated biphenyls exposure, at levels comparable with those of the general U.S. population, was associated with increased thyroglobulin antibodies and increased T(4) in adult males. |
|
2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| Dichlorodiphenyl Dichloroethylene
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| pentabrominated diphenyl ether 100
| Polychlorinated Biphenyls
|
Study subjects |
United States |
serum | urine |
2,2',4,4',5-brominated diphenyl ether
| 2,2',4,4'-tetrabromodiphenyl ether
| Dichlorodiphenyl Dichloroethylene
| Halogenated Diphenyl Ethers
| hexabrominated diphenyl ether 153
| pentabrominated diphenyl ether 100
| Polychlorinated Biphenyls
| SERPINA7
| Testosterone
| Thyrotropin
| Thyroxine
| Triiodothyronine
|
Details
|
immunoglobulin production
| testosterone biosynthetic process
| thyroid hormone metabolic process
|
| 25. |
Johansson GM, et al. (2015).
|
|
This first study of amine adducts in hairdressers and consumers identified an increase in o- and m-toluidine Hb-adduct concentrations among hairdressers, associated with the weekly number of hair dye and hair waving treatments performed. |
|
2,3-didehydro-5-O-mycaminosyl-23-O-acetyltylonolide
| 2-toluidine
| 3-toluidine
| 4-toluidine
|
Study subjects | Workers |
Sweden |
blood |
2,3-didehydro-5-O-mycaminosyl-23-O-acetyltylonolide
| 2-toluidine
| 3-toluidine
| 4-toluidine
|
Details
|
|
| 26. |
Goldner WS, et al. (2010).
|
Agricultural Health Study (AHS) |
These data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study. |
|
2,4,5-Trichlorophenoxyacetic Acid
| 2,4-Dichlorophenoxyacetic Acid
| alachlor
| Aldrin
| Atrazine
| Benomyl
| butylate
| Captan
| Carbaryl
| Carbon Disulfide
| Carbon Tetrachloride
| Chlordan
| chlorimuron ethyl
| Chlorpyrifos
| cyanazine
| DDT
| Diazinon
| Dicamba
| Dichlorvos
| EPTC
| Fonofos
| Fungicides, Industrial
| glyphosate
| Heptachlor
| Hydrocarbons, Chlorinated
| imazethapyr
| Insecticides
| Lindane
| Malathion
| mancozeb
| Maneb
| metalaxyl
| methyl bromide
| metolachlor
| metribuzin
| Paraquat
| Parathion
| pendimethalin
| Petroleum
| terbufos
| tetrachloroisophthalonitrile
| Trifluralin
|
Study subjects |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Hyperthyroidism
| Hypothyroidism
|
| 27. |
Hoppin JA, et al. (2007).
|
Agricultural Health Study (AHS) |
These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence. |
|
2,4,5-Trichlorophenoxyacetic Acid
| Carbaryl
| Carbofuran
| chlorimuron ethyl
| DDT
| Diazinon
| Dichlorvos
| fenoprop
| Heptachlor
| Malathion
| Permethrin
|
Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Bronchitis, Chronic
|
| 28. |
Koutros S, et al. (2011).
|
Agricultural Health Study (AHS) |
We evaluated pesticide-single nucleotide polymorphism (SNP) interactions between 45 pesticides and 1913 xenobiotic metabolic enzyme SNPs with respect to prostrate cancer among 776 cases and 1444 controls in the Agricultural Health Study. |
genetics |
2,4,5-Trichlorophenoxyacetic Acid
| Carbaryl
| Diazinon
| Dieldrin
| Fonofos
| Lindane
| methyl bromide
| Petroleum
| Phorate
| terbufos
|
Subjects with gene influence:GCLC
| Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Prostatic Neoplasms
|
| 29. |
Hoppin JA, et al. (2017).
|
Agricultural Health Study (AHS) |
We evaluated the association of currently used pesticides with allergic and non-allergic wheeze among male farmers, and our results implicate several pesticides that are commonly used in agricultural and residential settings with adverse respiratory effects. |
|
2,4-Dichlorophenoxyacetic Acid
| acetochlor
| Atrazine
| bentazone
| Carbaryl
| Chlorpyrifos
| clomazone
| clopyralid
| cyfluthrin
| Dicamba
| Dimethoate
| Disulfoton
| fenoxaprop ethyl
| fluazifop-butyl
| glyphosate
| Herbicides
| imazaquin
| Insecticides
| Malathion
| mesotrione
| metolachlor
| N-(2,6-difluorophenyl)-5-methyl(1,2,4)-triazol(1,5-a)pyrimidine-2-sulfonamide
| nicosulfuron
| Permethrin
| Petroleum
| Picloram
| Pyrethrins
| Rodenticides
| Simazine
| triclopyr
| Trifluralin
| Warfarin
|
Workers |
United States |
|
|
Details
|
Respiratory Sounds
| Rhinitis, Allergic
|
| 30. |
Hoppin JA, et al. (2002).
|
Agricultural Health Study (AHS) |
Prevalence of wheeze was associated with individual pesticides independent of animals, crops, and grains. |
disease |
2,4-Dichlorophenoxyacetic Acid
| alachlor
| Aldicarb
| aluminum phosphide
| Atrazine
| Benomyl
| butylate
| Captan
| Carbaryl
| Carbofuran
| chlorimuron ethyl
| Chlorpyrifos
| Coumaphos
| cyanazine
| Diazinon
| Dicamba
| Dichlorvos
| EPTC
| Fonofos
| glyphosate
| imazethapyr
| Lindane
| Malathion
| Maneb
| metalaxyl
| metolachlor
| metribuzin
| Paraquat
| Parathion
| pendimethalin
| Permethrin
| Petroleum
| Phorate
| terbufos
| tetrachloroisophthalonitrile
| Trichlorfon
| Trifluralin
| Ziram
|
Subjects with disease:Asthma
| Subjects with disease:Ige Responsiveness, Atopic
| Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Respiratory Sounds
|
| 31. |
Lee WJ, et al. (2007).
|
Agricultural Health Study (AHS) |
This explorative study suggests an association between the incidence of colorectal cancer and use of certain pesticides, in particularly chlorpyrifos and aldicarb, although some findings could be due to chance. |
age | body mass index | tobacco |
2,4-Dichlorophenoxyacetic Acid
| Aldicarb
| Carbaryl
| Chlorpyrifos
| Fonofos
| Toxaphene
|
Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Colorectal Neoplasms
| Rectal Neoplasms
|
| 32. |
Hoppin JA, et al. (2008).
|
Agricultural Health Study (AHS) |
These findings suggest that pesticides may contribute to atopic asthma, but not nonatopic asthma, among farm women. |
|
2,4-Dichlorophenoxyacetic Acid
| Carbamates
| Carbaryl
| Coumaphos
| DDT
| glyphosate
| Hydrocarbons, Chlorinated
| Malathion
| metalaxyl
| Organophosphates
| Parathion
| Permethrin
| Pesticides
| Phorate
|
Study subjects |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Asthma
|
| 33. |
Palacios C, et al. (2012).
|
|
In this group of overweight and obese individuals, 25-Hydroxyvitamin D was significantly related to vitamin D intake, sun exposure and vitamin D intake indices and percent body fat. |
body mass index | diet |
25-hydroxyvitamin D
| Vitamin D
|
Study subjects |
Puerto Rico |
serum |
25-hydroxyvitamin D
| Vitamin D
|
Details
|
|
| 34. |
Kioumourtzoglou MA, et al. (2013).
|
Aerosol Research and Inhalation Epidemiology Study (ARIES) |
Results suggest that week-long exposures to traffic-related, primary organic species are associated with increased rate of total and cause-specific cardiovascular disease emergency hospital admissions. |
|
9-fluorenone
| acenaphthylene
| benzo(b)fluoranthene
| benzo(e)pyrene
| benzo(k)fluoranthene
| chrysene
| Cyclohexane
| cyclopenta(c,d)pyrene
| docosane
| dotriacontane
| fluoranthene
| hentriacontane
| n-heneicosane
| nonacosane
| n-pentacosane
| n-tricosane
| octacosane
| Particulate Matter
| phenanthrene
| pyrene
| retene
| Soot
| tetracosane
| tritriacontane
|
Subjects with disease:Cardiovascular Diseases
| Subjects with disease:Coronary Disease
| Subjects with disease:Myocardial Infarction
| Subjects with disease:Pulmonary Disease, Chronic Obstructive
|
United States |
air |
9-fluorenone
| acenaphthylene
| benzo(b)fluoranthene
| benzo(e)pyrene
| benzo(k)fluoranthene
| chrysene
| Cyclohexane
| cyclopenta(c,d)pyrene
| docosane
| dotriacontane
| fluoranthene
| hentriacontane
| n-heneicosane
| nonacosane
| n-pentacosane
| n-tricosane
| octacosane
| phenanthrene
| pyrene
| retene
| Soot
| tetracosane
| tritriacontane
|
Details
|
Cardiovascular Diseases
| Coronary Disease
| Myocardial Infarction
| Pulmonary Disease, Chronic Obstructive
|
| 35. |
Logue JM, et al. (2012).
|
|
The approach demonstrated in this study may be used to assess regional and national initiatives that affect indoor air quality at the population level. Cumulative health impacts from inhalation in U.S. residences of the indoor air pollutants assessed in this study are estimated at 400-1,100 disability-adjusted life years lost annually per 100,000 persons. |
|
Air Pollutants
|
|
United States |
|
1,1,1,2-tetrachloroethane
| 1,1,2-trichloroethane
| 1,3-butadiene
| 2-butenal
| 2-ethoxyethanol
| 2-ethylhexanol
| 2-phenylphenol
| 2-xylene
| 4-dichlorobenzene
| Acetaldehyde
| Acrolein
| Acrylonitrile
| Ammonia
| Arsenic
| Atrazine
| Benzaldehydes
| Benzene
| Benzo(a)pyrene
| benzyl chloride
| Beryllium
| bromodichloromethane
| bromoform
| Cadmium
| Carbon Disulfide
| Carbon Monoxide
| Carbon Tetrachloride
| chlorobenzene
| chlorodibromomethane
| Chloroform
| Chromium
| cumene
| Cyclohexane
| Diethylhexyl Phthalate
| dioctyl adipate
| Ethanol
| ethylbenzene
| Ethyl Chloride
| Ethylene Dibromide
| ethylene dichloride
| Formaldehyde
| hexachlorobutadiene
| Manganese
| Mercury
| methyl cellosolve
| Methyl Chloride
| Methylene Chloride
| methylethyl ketone
| methyl isobutyl ketone
| Methylmethacrylate
| methyl tert-butyl ether
| naphthalene
| n-butoxyethanol
| Nitrogen Dioxide
| Ozone
| Particulate Matter
| Pentachlorophenol
| Styrene
| Sulfur Dioxide
| Tetrachloroethylene
| tetrahydrofuran
| Toluene
| Trichloroethylene
| Vinyl Chloride
| vinylidene chloride
| Xylenes
|
Details
|
|
| 36. |
Kalkbrenner AE, et al. (2010).
|
Autism and Developmental Disabilities Monitoring Network (ADDM) |
Our screening design was limited by exposure misclassification of air pollutants and the use of an alternate developmental disorder as the control group, both of which may have biased results toward the null. Despite these limitations, methylene chloride, quinoline, and styrene emerged (based on this analysis and prior epidemiologic evidence) as candidates that warrant further investigation for a possible role in autism etiology. |
|
Air Pollutants
|
|
United States |
air |
1,1,2,2-tetrachloroethane
| 1,3-butadiene
| 1,3-dichloro-1-propene
| Acetaldehyde
| Acrolein
| Acrylonitrile
| Arsenicals
| Benzene
| Beryllium
| Cadmium Compounds
| Carbon Tetrachloride
| Chloroform
| Chromium Compounds
| Coke
| ethylbenzene
| Ethylene Dibromide
| ethylene dichloride
| Ethylene Oxide
| Formaldehyde
| Hexachlorobenzene
| Hexanes
| hydrazine
| Lead
| Manganese Compounds
| Mercury Compounds
| Methylene Chloride
| methyl tert-butyl ether
| Nickel
| Polychlorinated Biphenyls
| Polycyclic Aromatic Hydrocarbons
| propionaldehyde
| propylene dichloride
| quinoline
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
| Vehicle Emissions
| Vinyl Chloride
| Xylenes
|
Details
|
Autism Spectrum Disorder
|
| 37. |
Windham GC, et al. (2006).
|
|
Our results suggest a potential association between autism and estimated metal concentrations, and possibly chlorinated solvents, in ambient air around the birth residence, requiring confirmation and more refined exposure assessment in future studies. |
|
Air Pollutants
|
Controls for disease:Autism Spectrum Disorder
| Subjects with disease:Autism Spectrum Disorder
| Children |
United States |
air, ambient |
Arsenic
| Benzene
| Cadmium
| Chromium
| ethylbenzene
| hydrazine
| Hydrocarbons, Chlorinated
| Lead
| Manganese
| Mercury
| Metals, Heavy
| Methylene Chloride
| Nickel
| Particulate Matter
| Polycyclic Aromatic Hydrocarbons
| Solvents
| Styrene
| Tetrachloroethylene
| Toluene
| Trichloroethylene
| Vinyl Chloride
| Xylenes
|
Details
|
Autism Spectrum Disorder
|
| 38. |
Wertheim HF, et al. (2012).
|
|
High levels of urine hydroxy-polycyclic aromatic hydrocarbons were found in Hanoi street workers. No effect was seen on urine levels by wearing R95 particulate respirators in an area of high urban air pollution, except for 1-hydroxynaphthalene. |
|
Air Pollutants
|
Workers |
Vietnam |
urine |
1-hydroxyphenanthrene
| 1-hydroxypyrene
| 2-hydroxyfluorene
| 4-hydroxyphenanthrene
| fluoren-9-ol
|
Details
|
|
| 39. |
López-Abente G, et al. (2012).
|
|
Statistically significant relative risks for colorectal cancer mortality at a municipal level were detected in the vicinity of mining industry, paper and wood production, food and beverage sector, metal production and processing installations, and ceramics. |
|
Air Pollutants
|
Study subjects |
Spain |
air, outdoor |
1,1,1-trichloroethane
| Ammonia
| anthracene
| Antimony
| Arsenicals
| Arsenic
| Benzene
| beta-hexachlorocyclohexane
| Cadmium
| Cadmium Compounds
| Carbon Dioxide
| Carbon Monoxide
| Carbon Tetrachloride
| Chlorine
| Chlorine Compounds
| Chlorofluorocarbons
| Chloroform
| Chromium
| Chromium Compounds
| Cobalt
| Diethylhexyl Phthalate
| Dioxins
| ethylene dichloride
| Ethylene Oxide
| Fluorine
| Fluorine Compounds
| Hexachlorobenzene
| Hydrogen Cyanide
| Lead
| Manganese
| Manganese Compounds
| Mercury
| Mercury Compounds
| Methane
| Methylene Chloride
| naphthalene
| Nickel
| Nitrogen Oxides
| Nitrous Oxide
| Particulate Matter
| Pentachlorophenol
| Polychlorinated Biphenyls
| Sulfur Oxides
| Tetrachloroethylene
| Thallium
| trichlorobenzene
| Trichloroethylene
| Vanadium
| Vanadium Compounds
| Vinyl Chloride
| Zinc
| Zinc Compounds
|
Details
|
Colorectal Neoplasms
| Death
|
| 40. |
Wittkopp S, et al. (2016).
|
Cardiovascular Health and Air Pollution Study |
We report novel associations of gene expression changes with traffic-related air pollution exposures in a Los Angeles cohort of elderly subjects with coronary artery disease in this exploratory panel study analysis. |
|
Air Pollutants
| Carbon
| Carbon Monoxide
| hopane
| Nitrogen Dioxide
| Nitrogen Oxides
| Organic Chemicals
| Ozone
| Particulate Matter
| Polycyclic Aromatic Hydrocarbons
| Soot
|
Subjects with disease:Coronary Artery Disease
|
United States |
air | blood |
Carbon
| Carbon Monoxide
| CYP1B1
| HMOX1
| hopane
| IL1B
| NFE2L2
| Nitrogen Dioxide
| Nitrogen Oxides
| NQO1
| Organic Chemicals
| Ozone
| Particulate Matter
| Polycyclic Aromatic Hydrocarbons
| SELP
| SOD2
| Soot
|
Details
|
gene expression
|
| 41. |
Delfino RJ, et al. (2010).
|
|
Traffic emission sources of organic chemicals represented by polycyclic aromatic hydrocarbons are associated with increased systemic inflammation and explain associations with quasi-ultrafine particle mass. |
|
Air Pollutants
| hopane
| Polycyclic Aromatic Hydrocarbons
| Vehicle Emissions
|
Subjects with disease:Coronary Artery Disease
|
United States |
air, outdoor | plasma |
Alkanes
| Chromium
| Copper
| hopane
| IL6
| Iron
| Manganese
| Nickel
| Particulate Matter
| Polycyclic Aromatic Hydrocarbons
| TNFRSF1B
| Vanadium
| Zinc
|
Details
|
|
| 42. |
Perera F, et al. (2008).
|
|
The findings indicate that neurobehavioral development in Tongliang children benefited by elimination of polycyclic aromatic hydrocarbons (PAH) exposure from the coal-burning plant, consistent with the significant reduction in PAH-DNA adducts in cord blood of children in the 2005 cohort. |
|
Air Pollutants
| Lead
| Mercury
| Polycyclic Aromatic Hydrocarbons
| Tobacco Smoke Pollution
|
Infants or newborns |
China |
blood, cord |
Lead
| Mercury
| polycyclic aromatic hydrocarbons-DNA adduct
| Tobacco Smoke Pollution
|
Details
|
Prenatal Exposure Delayed Effects
| cognition
| motor activity
|
| 43. |
Zhang J, et al. (2013).
|
Health Effects of an Air Pollution Reduction Trial (HEART) |
Changes in air pollution levels during the 2008 Summer Olympics (Beijing, China) were associated with acute changes in biomarkers of pulmonary and systemic inflammation, oxidative stress, and hemostasis and in measures of cardiovascular physiology (heart rate and systolic blood pressure) in healthy, young adults, supporting the hypothesized mechanistic pathways underlying the cardiorespiratory effects of air pollution. |
|
Air Pollutants
| Particulate Matter
|
Study subjects |
China |
air, ambient | air, breath, exhaled | blood |
1,12-benzoperylene
| 1,2,5,6-dibenzanthracene
| acenaphthylene
| Aluminum
| Arsenic
| Barium
| benz(a)anthracene
| Benzo(a)pyrene
| benzo(b)fluoranthene
| benzo(e)pyrene
| benzo(k)fluoranthene
| Cadmium
| Calcium
| Carbon
| Carbon Monoxide
| CD40LG
| Chromium
| chrysene
| Cobalt
| Copper
| fluoranthene
| fluorene
| indeno(1,2,3-cd)pyrene
| Iron
| Lead
| Magnesium
| Manganese
| Molybdenum
| Nickel
| Nitrites
| Nitrogen Dioxide
| Ozone
| Particulate Matter
| phenanthrene
| Phosphorus
| Potassium
| pyrene
| Selenium
| SELP
| Sodium
| Soot
| Sulfates
| Sulfur Dioxide
| Thallium
| Thorium
| Titanium
| Uranium
| Vanadium
| VWF
| Zinc
|
Details
|
platelet aggregation
| regulation of blood pressure
| regulation of heart rate
|
| 44. |
Gong J, et al. (2015).
|
|
Sampling data for pre-, during-, and post-Olympic time periods in Beijing (China), this study found evidence that 1-naphthylamine and 2-naphthylamine (co-assayed) and 1-hydroxypyrene can be used as biomarkers of exposure to general vehicle-emitted pollutants; more data are needed to confirm 1-aminopyrene as a biomarker of diesel combustion emissions. |
|
Air Pollutants
| Vehicle Emissions
|
Study subjects |
China |
air, ambient | urine |
1-aminopyrene
| 1-hydroxypyrene
| 1-Naphthylamine
| 2-Naphthylamine
| Carbon Monoxide
| Nitrates
| Nitrogen Dioxide
| Ozone
| Particulate Matter
| Polycyclic Aromatic Hydrocarbons
| pyrene
| Soot
| Sulfates
| Sulfur Dioxide
|
Details
|
|
| 45. |
Adetona O, et al. (2017).
|
|
In this study, we assessed occupational exposure to wildland fire smoke in wildland firefighters by measuring the urinary concentrations of hydroxylated metabolites of polycyclic aromatic hydrocarbons; our results suggest that hydroxylated PAHs (especially 4-hydroxyphenanthrene) may be useful biomarkers of wildland fire smoke exposure. |
|
Air Pollutants, Occupational
| Smoke
|
Workers |
United States |
air, ambient | urine |
1,6-anhydro-beta-glucopyranose
| 1-hydroxyphenanthrene
| 1-hydroxypyrene
| 1-naphthol
| 2-hydroxyfluorene
| 2-naphthol
| 4-hydroxyphenanthrene
| Carbon Monoxide
| Particulate Matter
| Polycyclic Aromatic Hydrocarbons
|
Details
|
|
| 46. |
Andreotti G, et al. (2010).
|
Agricultural Health Study (AHS) |
Using data from the Agricultural Health Study, we examined the association between body mass index (BMI) and the risk of cancer at 17 sites and the interaction between BMI and pesticide use. |
body mass index | tobacco |
alachlor
| Atrazine
| Carbaryl
| Carbofuran
| chlorimuron ethyl
| Chlorpyrifos
| cyanazine
| DDT
| Diazinon
| EPTC
| Fonofos
| glyphosate
| Hydrocarbons, Chlorinated
| imazethapyr
| Malathion
| methyl bromide
| metolachlor
| metribuzin
| Organophosphates
| pendimethalin
| Permethrin
| terbufos
| Trifluralin
|
Study subjects | Workers |
United States |
|
|
Details
|
Agricultural Workers' Diseases
| Breast Neoplasms
| Colonic Neoplasms
| Lung Neoplasms
|
| 47. |
Christensen CH, et al. (2016).
|
Agricultural Health Study (AHS) |
In this case-control study nested within the Agricultural Health Study cohort, we evaluated evidence of statistical interaction between pesticide exposure and single nucleotide polymorphisms in genes involved in steroid hormone signaling, metabolism, or regulation with the risk of prostate cancer. |
genetics |
alachlor
| butylate
| Carbaryl
| Dicamba
| Fonofos
| Malathion
| terbufos
|
Subjects with gene influence:ESR1
| Subjects with gene influence:HSD17B4
| Subjects with gene influence:SHBG
| Subjects with gene influence:SRD5A1
| Subjects with gene influence:SULT2A1
| Workers |
United States |
|
|
Details
|
Prostatic Neoplasms
|
| 48. |
Cakmak S, et al. (2014).
|
Canadian Health Measures Survey (CHMS) |
To investigate the association between volatile organic compounds measured in residential indoor air and lung function in the Canadian population Cycle 2 of the Canadian Health Measures Survey - a population based cross-sectional survey designed to be representative of the Canadian population - was carried out between 2009 and 2011. |
|
alpha-pinene
| Benzene
| caprylic aldehyde
| decanaldehyde
| Furaldehyde
| isoprene
| naphthalene
| n-hexanal
| nonanal
| Styrene
|
Children | Study subjects |
Canada |
air |
alpha-pinene
| Benzene
| caprylic aldehyde
| decanaldehyde
| Furaldehyde
| isoprene
| naphthalene
| n-hexanal
| nonanal
| Styrene
|
Details
|
regulation of respiratory gaseous exchange
|
| 49. |
Shin HM, et al. (2014).
|
Early Autism Risk Longitudinal Investigation (EARLI) |
A total of six phthalates, four personal care product ingredients, and five flame retardants were analyzed in household dust from 30 homes in three different regions in the U.S. |
|
Aminobenzoates
| Benzopyrans
| butylbenzyl phthalate
| Dibutyl Phthalate
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| diisononyl phthalate
| Flame Retardants
| octylmethoxycinnamate
| Tetrahydronaphthalenes
| triphenyl phosphate
| tris(1,3-dichloro-2-propyl)phosphate
| tris(chloroethyl)phosphate
|
|
United States |
dust |
Aminobenzoates
| Benzopyrans
| butylbenzyl phthalate
| Dibutyl Phthalate
| Diethylhexyl Phthalate
| diethyl phthalate
| diisobutyl phthalate
| diisononyl phthalate
| Flame Retardants
| octylmethoxycinnamate
| Tetrahydronaphthalenes
| triphenyl phosphate
| tris(1,3-dichloro-2-propyl)phosphate
| tris(chloroethyl)phosphate
|
Details
|
|
| 50. |
Kaye JA, et al. (2014).
|
|
The results support a comparatively high adjusted relative risk of liver injury among patients exposed concurrently to multiple antimicrobials and modest elevations in the risk for several antimicrobials used alone; however, we found little evidence of any strong effect of commonly used antimicrobials on the risk of liver injury. |
|
Amoxicillin
| Anti-Infective Agents
| Clavulanic Acid
| Doxycycline
| Levofloxacin
| moxifloxacin
|
Study subjects |
United States |
|
|
Details
|
Chemical and Drug Induced Liver Injury
|
Illuminating how chemicals affect human health.
Polycyclic Compounds