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Chemical Polyenes

1–50 of 1,768 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1,3-butadiene NADH dehydrogenase (ubiquinone) activity CYP2E1 [1,3-butadiene results in decreased NADH dehydrogenase (ubiquinone) activity] which results in increased activity of CYP2E1 protein 1: Mus musculus Liver | Mitochondria   1
2. 1,3-butadiene positive regulation of histone H3-K27 acetylation 1,3-butadiene results in increased positive regulation of histone H3-K27 acetylation 1: Mus musculus Liver   1
3. 1,3-butadiene cytochrome-c oxidase activity CYP2E1 [1,3-butadiene results in decreased cytochrome-c oxidase activity] which results in increased activity of CYP2E1 protein 1: Mus musculus Liver | Mitochondria   1
4. 1,3-butadiene succinate dehydrogenase (ubiquinone) activity CYP2E1 [1,3-butadiene results in decreased succinate dehydrogenase (ubiquinone) activity] which results in increased activity of CYP2E1 protein 1: Mus musculus Liver | Mitochondria   1
5. 1,3-butadiene NADH dehydrogenase (ubiquinone) activity 1,3-butadiene results in decreased NADH dehydrogenase (ubiquinone) activity 1: Mus musculus Liver | Mitochondria   1
6. 1,3-butadiene succinate dehydrogenase (ubiquinone) activity 1,3-butadiene results in decreased succinate dehydrogenase (ubiquinone) activity 1: Mus musculus Liver | Mitochondria   1
7. 1,3-butadiene negative regulation of histone H4-K16 acetylation 1,3-butadiene results in increased negative regulation of histone H4-K16 acetylation 1: Mus musculus Lung 1 gene: SIRT1 1
8. 1,3-butadiene histone H3-K56 acetylation 1,3-butadiene results in decreased histone H3-K56 acetylation 1: Mus musculus Lung   1
9. 1,3-butadiene regulation of DNA demethylation 1,3-butadiene affects regulation of DNA demethylation 1: Mus musculus Lung   1
10. 1,3-butadiene regulation of DNA demethylation 1,3-butadiene affects regulation of DNA demethylation 1: Mus musculus Liver   1
11. 1,3-butadiene positive regulation of histone H3-K27 trimethylation 1,3-butadiene results in increased positive regulation of histone H3-K27 trimethylation 1: Mus musculus Kidney   1
12. 1,3-butadiene cytochrome-c oxidase activity 1,3-butadiene results in decreased cytochrome-c oxidase activity 1: Mus musculus Liver | Mitochondria   1
13. 1,3-butadiene histone H4-K20 trimethylation 1,3-butadiene affects histone H4-K20 trimethylation 1: Mus musculus Kidney   1
14. 1,3-butadiene positive regulation of histone H3-K9 trimethylation 1,3-butadiene results in increased positive regulation of histone H3-K9 trimethylation 1: Mus musculus Kidney   1
15. 2,3,22,23-dioxidosqualene positive regulation of cholesterol biosynthetic process Ro 48-8071 [Ro 48-8071 results in decreased positive regulation of cholesterol biosynthetic process] which results in increased abundance of 2,3,22,23-dioxidosqualene 1: Mus musculus     1
16. 2,3-oxidosqualene positive regulation of cholesterol biosynthetic process Ro 48-8071 [Ro 48-8071 results in decreased positive regulation of cholesterol biosynthetic process] which results in increased abundance of 2,3-oxidosqualene 1: Mus musculus     1
17. 2-amino-4-(4'-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene hypotonic response Sodium Chloride | Taurine 2-amino-4-(4'-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene inhibits the reaction [[Sodium Chloride deficiency results in increased hypotonic response] which results in increased secretion of Taurine] 1: Rattus norvegicus Hippocampus   1
18. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of epithelial cell differentiation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased positive regulation of epithelial cell differentiation 1: Mus musculus Embryo, Mammalian | Testis | Epithelial Cells | Cell Line, Tumor 1 gene: CDKN2B 1
19. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid cell proliferation CPG-oligonucleotide 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [CPG-oligonucleotide results in increased cell proliferation] 1: Homo sapiens B-Lymphocytes | Cells, Cultured
4 genes: AKT1 | BAX | BCL2 | HGF
1
20. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid L-cystine transport Cystine [[4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased L-cystine transport] which results in decreased import of Cystine] which results in increased abundance of Cystine 1: Homo sapiens Induced Pluripotent Stem Cells | Extracellular Fluid   1
21. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid L-cystine transport Ro 41-5253 Ro 41-5253 inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased L-cystine transport] 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
22. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid L-cystine transport Cystine | Ro 41-5253 Ro 41-5253 inhibits the reaction [[[4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased L-cystine transport] which results in decreased import of Cystine] which results in increased abundance of Cystine] 1: Homo sapiens Induced Pluripotent Stem Cells | Extracellular Fluid   1
23. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid lung epithelial cell differentiation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid affects lung epithelial cell differentiation 1: Homo sapiens Bronchi | Epithelial Cells | Cells, Cultured   1
24. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of cell proliferation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased positive regulation of cell proliferation 1: Mus musculus Keratinocytes | Cell Line, Transformed
15 genes: AKT1 | BCL2 | CCND1 | CCND3 | CDKN1B | FABP4 | HGF | HOXC10 | IL2 | INS | PDGFB | RARA | RARB | RARG | STS
1
25. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid cell proliferation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased cell proliferation 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor
4 genes: AKT1 | BAX | BCL2 | HGF
1
26. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid cholesterol metabolic process cholesteryl sulfate [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid affects cholesterol metabolic process] which results in decreased abundance of cholesteryl sulfate 1: Oryctolagus cuniculus Trachea | Epithelial Cells | Cells, Cultured 1 gene: RXRA 1
27. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of cell proliferation RARG RARG gene mutant form inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased positive regulation of cell proliferation] 1: Mus musculus Keratinocytes | Cell Line, Transformed
15 genes: AKT1 | BCL2 | CCND1 | CCND3 | CDKN1B | FABP4 | HGF | HOXC10 | IL2 | INS | PDGFB | RARA | RARB | RARG | STS
1
28. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of G1/S transition of mitotic cell cycle INS | PDGFB 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased positive regulation of G1/S transition of mitotic cell cycle] 1: Homo sapiens Coronary Vessels | Muscle, Smooth, Vascular | Cells, Cultured   1
29. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid L-cystine transport Cystine | Ro 41-5253 Ro 41-5253 inhibits the reaction [[4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased L-cystine transport] which results in decreased import of Cystine] 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
30. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of epithelial cell differentiation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased positive regulation of epithelial cell differentiation 1: Oryctolagus cuniculus Trachea | Epithelial Cells | Cells, Cultured 1 gene: CDKN2B 1
31. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of retinoic acid receptor signaling pathway 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased positive regulation of retinoic acid receptor signaling pathway 1: Homo sapiens Bronchi | Epithelial Cells | Cells, Cultured   1
32. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid ornithine catabolic process 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased ornithine catabolic process 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
33. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid pericardium morphogenesis triphenyl phosphate 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid inhibits the reaction [triphenyl phosphate results in increased pericardium morphogenesis] 1: Danio rerio Embryo, Nonmammalian | Pericardium   1
34. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid cell proliferation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid analog results in decreased cell proliferation 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor
4 genes: AKT1 | BAX | BCL2 | HGF
1
35. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of retinoic acid receptor signaling pathway 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased positive regulation of retinoic acid receptor signaling pathway 1: Mus musculus Embryo, Mammalian | Fibroblasts | Cell Line   1
36. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid L-cystine transport Cystine [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased L-cystine transport] which results in decreased import of Cystine 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
37. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid L-cystine transport 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased L-cystine transport 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
38. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of cell proliferation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased positive regulation of cell proliferation 1: Mus musculus Melanocytes | Cell Line, Tumor
15 genes: AKT1 | BCL2 | CCND1 | CCND3 | CDKN1B | FABP4 | HGF | HOXC10 | IL2 | INS | PDGFB | RARA | RARB | RARG | STS
1
39. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid cholesterol metabolic process 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid affects cholesterol metabolic process 1: Oryctolagus cuniculus Trachea | Epithelial Cells | Cells, Cultured 1 gene: RXRA 1
40. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of DNA binding transcription factor activity 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased positive regulation of DNA binding transcription factor activity 1: Homo sapiens Bronchi | Epithelial Cells | Cells, Cultured
2 genes: AKT1 | PPARG
1
41. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid apoptotic process 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in decreased apoptotic process 1: Homo sapiens T-Lymphocytes | Cells, Cultured
6 genes: AKT1 | BAX | BCL2 | CASP3 | GJA1 | RB1
1
42. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of granulocyte differentiation 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased positive regulation of granulocyte differentiation 1: Homo sapiens HL-60 Cells   1
43. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid positive regulation of DNA biosynthetic process INS | PDGFB 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased positive regulation of DNA biosynthetic process] 1: Homo sapiens Coronary Vessels | Muscle, Smooth, Vascular | Cells, Cultured
2 genes: HGF | PDGFB
1
44. 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid cell proliferation Tetradecanoylphorbol Acetate 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased cell proliferation] 1: Homo sapiens T-Lymphocytes | Cells, Cultured
4 genes: AKT1 | BAX | BCL2 | HGF
1
45. 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid drug metabolic process 4-oxoretinoic acid [4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid results in increased drug metabolic process] which results in increased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Lung | Cell Line, Tumor   1
46. 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid drug metabolic process Tretinoin [4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid results in increased drug metabolic process] which results in increased metabolism of Tretinoin 1: Homo sapiens Lung | Cell Line, Tumor   1
47. 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid drug metabolic process 4-hydroxyretinoic acid [4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Lung | Cell Line, Tumor   1
48. 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid drug metabolic process 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid results in increased drug metabolic process 1: Homo sapiens Lung | Cell Line, Tumor   1
49. 4-amino-2-trifluoromethyl-phenyl retinate positive regulation of myeloid leukocyte differentiation 3-methyladenine 3-methyladenine inhibits the reaction [4-amino-2-trifluoromethyl-phenyl retinate results in increased positive regulation of myeloid leukocyte differentiation] 1: Homo sapiens Myeloid Progenitor Cells | Cell Line, Tumor   1
50. 4-amino-2-trifluoromethyl-phenyl retinate positive regulation of autophagy ATG5 ATG5 protein promotes the reaction [4-amino-2-trifluoromethyl-phenyl retinate results in increased positive regulation of autophagy] 1: Homo sapiens Myeloid Progenitor Cells | Cell Line, Tumor 1 gene: BECN1 1
1–50 of 1,768 results.