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Chemical Pro-Opiomelanocortin

Name Pro-Opiomelanocortin
CAS Type 1 Name Opiomelanocortin, pro-
Equivalent Terms ACTH beta Lipotropin Precursor | ACTH-beta-Lipotropin Precursor | ACTH Endorphin Precursor | ACTH-Endorphin Precursor | Corticotropin beta Lipotropin Precursor | Corticotropin-beta-Lipotropin Precursor | Endorphin ACTH Precursor | Endorphin-ACTH Precursor | Opiocortin | POMC | Pre POMC | Pre-POMC | Pre pro opiocortin | Pre-pro-opiocortin | Preproopiomelanocortin | Pro ACTH Endorphin | Pro-ACTH-Endorphin | Proopiocortin | Pro Opiocortin | Pro-Opiocortin | Proopiomelanocortin | Pro Opiomelanocortin | Pro Opio Melanocortin | Pro-Opio-Melanocortin
CAS Registry Number 66796-54-1
Definition A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
Top Interacting
Genes
MeSH® ID D011333
External Links

Top ↑ Ancestors

1. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Hypothalamic Hormones Has associated genes Has associated diseases Pro-Opiomelanocortin Has associated genes Has associated diseases
2. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Pituitary Hormones Has associated genes Has associated diseases Has associated exposure references Pituitary Hormones, Anterior Has associated genes Has associated diseases Has associated exposure references Pro-Opiomelanocortin Has associated genes Has associated diseases
3. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Neuropeptides Has associated genes Has associated diseases Hypothalamic Hormones Has associated genes Has associated diseases Pro-Opiomelanocortin Has associated genes Has associated diseases
4. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Hypothalamic Hormones Has associated genes Has associated diseases Pro-Opiomelanocortin Has associated genes Has associated diseases
5. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Pituitary Hormones Has associated genes Has associated diseases Has associated exposure references Pituitary Hormones, Anterior Has associated genes Has associated diseases Has associated exposure references Pro-Opiomelanocortin Has associated genes Has associated diseases

Top ↑ Descendants

Pro-Opiomelanocortin Has associated genes Has associated diseases
  alpha-Endorphin
View node alpha-MSH Has associated genes Has associated diseases
View node beta-Endorphin Has associated genes Has associated diseases
View node beta-Lipotropin
View node beta-MSH Has associated genes Has associated diseases
  Corticotropin-Like Intermediate Lobe Peptide Has associated diseases
  gamma-Endorphin Has associated diseases
  gamma-Lipotropin
View node gamma-MSH
  joining peptide, pro-opiomelanocortin
View node Melanocortins Has associated genes Has associated diseases
  MSH, Lys-gamma(2)
  MSH, Lys-gamma(3)
  N-POMC (1-28)
  POMC protein, zebrafish
  proopiocortin fragments
  pro-opiomelanocortin (1-49)
  pro-opiomelanocortin (1-77)
  pro-opiomelanocortin amino-terminal glycopeptide
  Proopiomelanocortin Deficiency
  pro-opiomelanocortin human joining peptide(77-109)
  pro-opiomelanocortin joining peptide(14-23)
  pro-opiomelanocortin joining peptide(77-97)
  pro-opiomelanocortin joining peptide(79-108)