These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Mi T, et al. (2013).||We describe two cases of acute toxic leukoencephalopathy in migrant workers who were occupationally exposed to organic solvents in construction materials.||1,2,3-trichloropropane | Solvents | Toluene||Workers||China||blood | urine||1,2,3-trichloropropane | Benzoic Acid||Details||Leukoencephalopathies | Neurotoxicity Syndromes | Occupational Diseases|
|2.||Kalkbrenner AE, et al. (2010).||Autism and Developmental Disabilities Monitoring Network (ADDM)||Our screening design was limited by exposure misclassification of air pollutants and the use of an alternate developmental disorder as the control group, both of which may have biased results toward the null. Despite these limitations, methylene chloride, quinoline, and styrene emerged (based on this analysis and prior epidemiologic evidence) as candidates that warrant further investigation for a possible role in autism etiology.||Air Pollutants||United States||air||1,1,2,2-tetrachloroethane | 1,3-butadiene | 1,3-dichloro-1-propene | Acetaldehyde | Acrolein | Acrylonitrile | Arsenicals | Benzene | Beryllium | Cadmium Compounds | Carbon Tetrachloride | Chloroform | Chromium Compounds | Coke | ethylbenzene | Ethylene Dibromide | ethylene dichloride | Ethylene Oxide | Formaldehyde | Hexachlorobenzene | Hexanes | hydrazine | Lead | Manganese Compounds | Mercury Compounds | Methylene Chloride | methyl tert-butyl ether | Nickel | Polychlorinated Biphenyls | Polycyclic Aromatic Hydrocarbons | propionaldehyde | propylene dichloride | quinoline | Styrene | Tetrachloroethylene | Toluene | Trichloroethylene | Vehicle Emissions | Vinyl Chloride | Xylenes||Details||Autism Spectrum Disorder|
|3.||Padhi BK, et al. (2017).||Burning of household fuels could be a major source of endotoxin in homes; we measured endotoxin levels in different size fractions of particulate matter (PM10, PM2.5, and PM1) in homes using LPG (propane) vs. biomass fuel (complex mixtures), and estimated the deposition of particle-bound endotoxin in the respiratory tract.||Complex Mixtures | Particulate Matter | Propane||Study subjects||India||air, indoor | lung||Carbon | Carbon Dioxide | Endotoxins | Particulate Matter||Details||Lung Diseases, Interstitial|
|4.||Kumagai S, et al. (2013).||These findings suggest that 1,2-dichloropropane (propylene dichloride) and/or dichloromethane (methylene chloride) may cause intrahepatic cholangiocarcinoma in humans.||Methylene Chloride | propylene dichloride||Workers||Japan||Methylene Chloride | propylene dichloride||Details||Cholangiocarcinoma | Death|
|5.||Yamada K, et al. (2015).||Our findings suggest that dichloromethane may contribute to the development of cholangiocarcinoma in humans.||Methylene Chloride | propylene dichloride||Subjects with disease:Cholangiocarcinoma||Japan||Methylene Chloride | propylene dichloride||Details||Cholangiocarcinoma|