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Chemical Epoprostenol

Name Epoprostenol
CAS Type 1 Name Prosta-5,13-dien-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (5Z,9alpha,11alpha,13E,15S)-
Equivalent Terms Epoprostanol | Epoprostenol Sodium | Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer | Flolan | PGI2 | PGX | Prostacyclin | Prostaglandin I2 | Prostaglandin I(2)
CAS Registry Number 35121-78-9
Definition A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
Structure Epoprostenol
Top Interacting
Genes
MeSH® ID D011464
External Links

Top ↑ Ancestors

1. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Prostaglandins Has associated genes Has associated diseases Has associated exposure references Prostaglandins I Has associated genes Has associated diseases Epoprostenol Has associated genes Has associated diseases
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Inflammation Mediators Has associated genes Has associated diseases Has associated exposure references Autacoids Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Prostaglandins Has associated genes Has associated diseases Has associated exposure references Prostaglandins I Has associated genes Has associated diseases Epoprostenol Has associated genes Has associated diseases

Top ↑ Descendants

Epoprostenol Has associated genes Has associated diseases
  10,10-difluoro-13-dehydroprostacyclin
  11-desoxyprostacyclin
  13,14-dehydroprostaglandin I2
  13,14-dehydroprostaglandin I2 methyl ester
  13,14-didehydro-20-methylcarboprostacyclin
  13,14-dinor-inter-p-phenylene carbacyclin
  15-cyclopentyl-7-oxo-prostaglandin I2-ephedrine
  15-deoxy-16-m-tolyl-17,18,19,20-tetranorisocarbacyclin
  15-deoxy-(16-m-tolyl)-17,18,19,20-tetranorisocarbacyclin methylester
  15-fluoro-13,14-dehydrocarbacyclin
  15-ketoprostaglandin I2
  16-tolyl-17,18,19,20-tetranorisocarbacyclin
  17,20-dimethylisocarbacyclin
  19-(3-azidophenyl)-20-norisocarbacyclin
  20-methyl-13,14-didehydro-2,4-inter-3-phenylene prostaglandin I2
  2,2,10,10-tetrafluoro-13-dehydroprostacyclin
  3-oxa-9(O)-methano-delta(6,9)prostaglandin I(1)
  3-oxacarbacyclin
  3-oxahomoisocarbacyclin
  4,5-didehydroisocarbacyclin
  5,6-dihydroprostacyclin
  5-hydroxyprostaglandin I
  5-methyleneisocarbacyclin
  5-nitroprostaglandin I1
  5-nitroprostaglandin I2
  6,9-thiaprostacyclin
  6a-carbaprostaglandin I3
  7a-homo-2-norprostacyclin
  7-fluoroprostacyclin
  7-oxo-cyclopentyl-prostaglandin I2
  7-oxoprostaglandin I2 Has associated diseases
  7-oxo-prostaglandin I2-ephedrine
  9-O-methanoprostaglandin I
  AFP 03
  AFP 06
  AFP 07
  APS 306
  ataprost
  benzodioxane prostacyclin
  beraprost Has associated genes Has associated diseases
  bicyclo(4.3.0)non-2-ene homoisocarbacyclin
  carboprostacyclin Has associated genes Has associated diseases
  CG 4303
  Chinoin 7284
  Chinoin 7384
  cicaprost Has associated genes Has associated diseases
  ciprostene
  CL 115999
  dehydro-15-cyclohexylcarbaprostacyclin
  dihomo-prostaglandin I(2)
  FCE 21258
  HOE 892
  homoisocarbacyclin
  KAG-308
  KP 10614
  MM 706
  naxaprostene
  nileprost
  nitriloprostaglandin I2
  OP 2507
  OP 41483-alpha-cyclodextrin
  Osaka University cocktail
  PFC-Kyoto solution
  piriprost
  prostaglandin I2 11-methyl ether
  prostaglandin I2 15-methyl ether
  prostaglandin I2 methyl ester
  prostaglandin I3 Has associated genes Has associated diseases
  R 59274
  SC 39902
  SM 10902
  SM 10906
  taprostene
  TEI 1324
  TEI 3356
  TEI 4343
  TEI 9090
  TFC 132
  tilsuprost
  treprostinil Has associated genes Has associated diseases
  TRY 200
  TTC 909
  TY 10957
  TY 11223
  U 56467
  U 68215
  U 72382