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Chemical Purines

Name Purines
Definition A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.
Top Interacting
Genes
MeSH® ID D011687
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Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Purines Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references

Top ↑ Descendants

Purines Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references
  10,13-dimethyl-17-(2-(6-sulfanylidene-3H-purin-9-yl)acetyl)-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-3-one
  1-(2-(2,6-dimethylsulfanyl-9H-purin-9-yl)-2-methylidenepropyl)-4,6-bis(methylsulfanyl)-1H-pyrazolo(3,4-d)pyrimidine
  1,2,6,8b-tetrahydro-5-methyl-2-(1-methylethyl)-7-(4-methylpentyl)imidazo(2,1-e)purine-5(4H)-one
  1,3-dibutyl-7-(hydroxypropyl)-1H-purine-2,6(3H,7H)-dione
  1,5-pyrimidino-6,9-purinophane
  1,6-dihydro-6-(hydroxymethyl)-9-(2-hydroxy-3-nonyl)purine
  1-(9-(4-chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl)-4-ethylaminopiperidine-4-carboxylic acid amide
  1-benzyl-7-methyl-3-propyl-1H,8H-imidazo(2,1-f)purine-2,4-dione
  1-benzylwye
  1H-imidazo(4,5-b)pyridine
  1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7-((5-methyl-1,2,4-oxadiazol-3-yl)methyl)-
  (1'S,2'S)-2-amino-9-((2'-hydroxyethyl-1'-(methyl)cycloprop-1'-yl)methyl)-6-chloropurine
  2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide Has associated genes Has associated diseases Has associated phenotype references
  2-(2-(hydroxymethyl)pyrrolidinyl)-6-((3-iodophenyl)methylamino)-9-isopropylpurine
  2,3,8,9-tetrahydro-2-thioxo-7H-(1,3)thiazino(2,3-i)purin-5-(1H)-one
  2-(4-morpholinoanilino)-6-cyclohexylaminopurine
  2,6,8-trichloropurine
  2,6-diamino-5,8-diaza-7,9-dicarba-purine
  2,6-diamino-9-benzyl-9-deazapurine
  2,6-diaminopurine aglycone
  2,6-dichloro-9-(1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)-9H-purine
  2,6-dichloropurine
  2,6-dioxo-8-aza-9-N-ribitylpurine
  2,6-dioxo-9-N-ribitylpurine
  2,6-dithiopurine Has associated diseases
  (2,9)(6,9)-purinophane
  2-amino-6-(2-furanyl)purine
  2-amino-6-(2-thienyl)purine
  2-amino-6-(4-methoxyphenylthio)-9-(2-(phosphonomethoxy)ethyl)purine bis(2,2,2-trifluoroethyl) ester Has associated diseases
  2-amino-6-chloro-9-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)purine
  2-amino-6-chloro-9-((5-dihydroxyboryl)pentyl)purine
  2-amino-6-fluoro-9-(4-hydroxy-3-hydroxymethylbutyl)purine
  2-amino-6-(N,N-dimethylamino)purine
  2-amino-6-vinylpurine
  2-amino-9-(3-hydroxymethyl-4-isopropoxycarbonyloxybut-1-yl)pyrine
  2-amino-deoxyribosylpurine
  2-chloro-6-(2-furyl)-9-(4-methoxyphenylmethyl)-9H-purine
  2-fluoro-9-benzylpurine
  2-hydroxy-6-methylpurine
  2-mercaptopurine Has associated phenotype references
  2-O-(4'-(N-9''-purinyl)butyl) myo-inositol 1,4,5-tris(phosphate)
  2-oxopurine
  2-phenyl-9H-purine-6-carbonitrile
  2-(pyrido(1,2-e)purin-4-yl)amino-ethanol
  (2R,3R,4R)-2-(2-chloro-6-(3-bromobenzylamino)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol
  (2R,3R,4S,5R)-2-(6-amino-2-(((1S)-2-hydroxy-1-(phenylmethyl)ethyl)amino)-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol
  3'-(1-chloroethyl)-2,3-dihydro-1H-imidazo(2,1-i)purine-4-ium-7-yl-3'-deoxy-1',5',6'-tri-O-(methylsulfonyl)-muco-inositol chloride
  3-(2-(4-aminophenyl)ethyl)-8-benzyl-7-(2-ethyl(2-hydroxyethyl)aminoethyl)-1-propyl-3,7-dihydropurine-2,6-dione
  3-(2-chlorobenzyl)-1,7-dimethyl-1H-imidazo(2,1-f)purine-2,4(3H,8H)-dione
  3-((2-hydroxyethoxy)methyl)-6-methyl-3H-imidazolo(1,2-a)purin-9(5H)-one dihydrate
  3-((3-(9H-purin-6-yl)pyridin-2-yl)amino)-N-(4-chloro-3-methylphenyl)-4-methylbenzamide
  3-(3-cyclopentyloxy-4-methoxybenzyl)-6-ethylamino-8-isopropyl-3H-purine Has associated phenotype references
  3,4-dipropyl-4,5,7,8-tetrahydro-3H-imidazo(1,2-i)purin-5-one
  3-(6-amino-8-(3-fluorophenyl)-2-(2-(1-hydroxycyclohexyl)-1-ethynyl)-9H-9-purinyl)benzamide
  3,7-dihydro-3-methyl-7-((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl)-6 H-purin-6-one
  3,7-dihydro-3-methyl-7-((2E,6E,10Z)-3,7,11,15-tetramethyl-13-oxohexadeca-2,6,10-trien-1-yl)-6H-purin-6-one
  3,9-dihydro-3-((1,3-dihydroxy-2-propoxy)methyl)-9-oxo-6-(4-(phenoxycarbonyloxy)phenyl)-5H-imidazo(1,2-a)purine
  3,9-dihydro-3-((2-hydroxyethoxy)methyl)-9-oxo-6-(4-(phenoxycarbonyloxy)phenyl)-5H-imidazo(1,2-a)purine
  3-(9H-purin-6-ylthio)acrylic acid
  3-ethyl-1-propyl-8-(1-(3-trifluoromethylbenzyl)-1H-pyrazol-4-yl)-3,7-dihydropurine-2,6-dione
  (3-fluoro-(2-phosphonoethoxy)propyl)purine
  3MB-PP1
  3-(pyrido(1,2-e)purin-4-ylsulfanyl)-2-propanol
  3-((tetrahydrofuran-2-yl)methyl)-2-thioxo-7H-purin-6-one
  4-(2-amino-6-chloro-9H-purin-9-yl)-1,3-dioxolane-2-methanol
  (4-2-aminopurin-9-yl)-1,3-dioxolane-2-methanol
  4-(2-chloro-6-(3-chlorobenzylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo(3.1.0)hexane-1-carboxamide
  4-(4-((5,7-dimethyl-2-ethyl-3H-imidazo(4,5-b)pyridin-3-yl)methyl)phenyl)-3-(2H-tetrazol-5-yl)quinoline
  4-(6-cyclohexylmethoxy-9H-purin-2-ylamino)-N,N-diethylbenzamide Has associated genes Has associated diseases
  4-(6-ethynyl-9H-purin-2-ylamino)benzenesulfonamide
  4-(6'-thiopurine)-7-chloroquinoline
  4-(9-(tetrahydrofuran-3-yl))-8-(2,4,6-trifluorophenylamino)-9H-purin-2-ylaminocyclohexan-1-ol
  4-(9-(tetrahydrofuran-3-yl)-8-(2,4,6-trifluorophenylamino)-9H-purin-2-ylamino)cyclohexanol
  4-allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo(2,1-i)purin-5(4H)-one Has associated genes Has associated diseases
  4-amino-6-(((6-chloro-2-methoxyacridin-9-yl)aminopropyl)amino)-7,8-dihydroimidazo(1,2-e)purine
  4-fluoro-4-(1,2,3,6-tetrahydro-1,3-dimethyl-2-oxo-6-thionpurin-8-ylthio)butyrophenone
  4-nitro-1,3-dideazapurine
  5,6,7,9-tetrahydro-7-hydroxy-9-oxoimidazo(1,2-a)purine
  5,6,7,9-tetrahydro-9-oxoimidazo(1,2-a)purine
  5-n-butyl-8-(4-methoxyphenyl)-3H-(1,2,4)triazolo(5,1-i)purine
  5-n-butyl-8-(4-n-propoxyphenyl)-3H-(1,2,4)triazolo(5,1-i)purine
  6-(2-acetylvinylthio)purine
  6-(2-butylimidazol-1-yl)-2-chloro-9-ethylpurine
  6-(3,5-dimethylpyrazol-1-yl)purine
  6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine Has associated genes Has associated diseases Has associated phenotype references
  6-(3-chlorobenzylamino)purine
  6-(3'-chloropropylthio)purine
  6-(3-hydroxybenzylamino)-9-tetrahydrofuran-2-ylpurine
  6-(3-hydroxybenzylamino)-9-tetrahydropyran-2-ylpurine
  6-(3-iodo-benzyloxy)-9H-purin-2-ylamine
  6-(3'-(thioethylamine)propylthio)purine
  6-(4-(18)fluoro-benzyloxy)-9H-purin-2-ylamine
  6-(4-nitrobenzylsulfanyl)-9-(4'-trifluoromethylbiphenyl-2-ylmethyl)purine
  6,6'-azopurine
  6-(6'-deoxy-1'-O-methyl-beta-D-ribofuranose)purine
  6-amino-2-chloropurine
  6-amino-alpha-((4-diphenylmethyl-1-piperazinyl)methyl)-9H-purine-9-ethanol
  6-benzylamino-7H-purin-3-ium p-toluenesulfonate
  6-benzylamino-9-(2-tetrahydropyranyl)-9H-purine
  6-benzyloxy-7-(2-fluoroethyl)-7H-purine-2-yl-amine
  6-benzyloxy-9-(2-fluoroethyl)-9H-purin-2-yl-amine
  6-bromo-7-methylpurine
  6-(bromomethyl)-9H-purine
  6-chloro-2-iodopurine
  6-chloro-7-(4-(4-chlorobenzyl)piperazin-1-yl)-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo(4,5-b)pyridine
  6-chloro-7-methylpurine
  6-chloro-9-(1,4-oxathian-2-yl)-9H-purine
  6-chloro-9-(1,4-oxathian-3-yl)-9H-purine
  6-chloro-9-(2-(hydroxymethyl)cyclopentylmethyl)-9H-purine
  6-chloro-9-(2(hydroxymethyl)cyclopentyl)purine
  6-chloropurine
  6-cyanopurine
  6-cyclopentylthio-9-hydroxymethylpurine
  6-dimethylamino-9-(2-hydroxy-3-(4-methoxyphenyl-L- alanylamino)propyl)purine
  6-(dimethylamino)-9-(4-methylbenzyl)-2-(trifluoromethyl)-9H-purine
  6-fluoro-9-benzylpurine
  6-fluoropurine
  6-hydroxy-9-(4-aminobenzyl)purine
  6-methoxypurine
  6-methylpurine
  6-methylpurine 7-N-oxide
  6-methylsulfinyl purine
  6-methylsulfonylpurine
  6-(octadecylthio)purine
  7-(1',2'-dihydroxyheptyl)-3h-imidazo(2,1-i)purine
  7,8-dihydro-8-ethyl-2-(4-bicyclo(2.2.2)octan-1-ol)-4-propyl-1H-imidazo(2,1-i)purin-5(4H)-one Has associated genes Has associated diseases
  7-but-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one
  7-deazapurine
  8,8'-dioxo-6,6'-azopurine
  8-azapurine Has associated genes Has associated diseases
  8-bromo-6-(dimethylamino)-9-(3-formamidobenzyl)-9H-purine
  8-cyclopentyl-2,6-diphenylpurine
  8-ethyl-4-methyl-2-phenyl-4,5,7,8-tetrahydro-1H-imidazo(2,1-i)purin-5-one Has associated genes Has associated diseases
  9-(2-deoxy-erythro-pentofuranosyl)-6-methylpurine
  9-(2-deoxy-ribofuranosyl)purine-2-thione
  9-(2-fluorobenzyl)-6-(methylamino)-9H-purine
  9-(2-hydroxy-3-nonyl)purine
  9-(2-hydroxybenzyl)-6-(4-nitrobenzylsulfanyl)purine
  9-benzyl-2-chloro-6-(2-furyl)purine
  9-(ethylcarboxymethyl)-6-(decylthio)-9H-purine
  9-(ethylcarboxymethyl)-6-(dodecylthio)-9H-purine
  9H-purine-9-propanamine, 6-amino-8-((6-iodo-1,3-benzodioxol-5-yl)thio)-N-(1-methylethyl)- Has associated genes Has associated diseases Has associated phenotype references
  9-isopropyl-6-(4-methoxy-benzylamino)-9H-purine-2-carboxylic acid isopropylamide
  9-norbornyl-6-chloropurine
  9-oxo-imidazo(1,2-a)purine
  9-ribityl-1,3,7-trihydro-2,6,8-purinetrione
  adecypenol
  AEE 788 Has associated genes Has associated diseases
  agelasine B
  agelasine D
  agelasine F
View node Allopurinol Has associated genes Has associated diseases Has associated phenotype references
  allylamine-N-dodecylallylamine-N-(purin-6-yl) allylamine copolymer
  AM-0902
  amipurimycin
  AP23236
  ATL 146e Has associated genes Has associated diseases Has associated phenotype references
  BCH 1393 Has associated genes Has associated diseases
  benzothiocarboxypurine
  benzylaminopurine
  bohemine Has associated genes Has associated diseases
  BWA 947U
  CAL-130
  catena-poly((diaqualithium(I))-mu-(9H-purine-2,6(1H,3H)-dionato-O(2)-N(&)))
  CB002
  CC-359
  CGP 57380 Has associated genes Has associated diseases
  cis-3-(9H-purin-6-ylthio)-acrylic acid
  cis-3-(9H-purin-6-ylthio)-acrylic acid-g-carboxymethyl chitosan
  cis-((7-(6-chloro-9H-purin-9-yl)methyl)-2,3-diphenyl-6,7-dihydro-5H-cyclopenta(b)pyrazin-5-yl)methanol
  CP-532,903
  CR8 compound Has associated genes Has associated diseases
  CVT 2759
  CVT 3033
  CVT 313 Has associated genes Has associated diseases Has associated phenotype references
  diethyl (6-amino-9H-purin-9-yl) methylphosphonate
  diminutol Has associated phenotype references
  etophylin
  GI270384X
  GNE-293
  Gpact-11a compound
  GSK 977779
  GV-58 compound
  heteromine D
  heteromine E
  HOE 602
  HOE 961
  idelalisib Has associated genes Has associated diseases Has associated phenotype references
  INU-152
  IPI-145
  istradefylline Has associated genes Has associated diseases Has associated phenotype references
  Jentadueto
  KF 26777
  KI 7
  Linagliptin Has associated genes Has associated diseases Has associated phenotype references
  lomeguatrib Has associated genes Has associated diseases
  MDL 74428
  meralluride
View node Mercaptopurine Has associated genes Has associated diseases Has associated phenotype references
  methazathioprine
  microxine
  myoseverin
  N-(1-(8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl)-4-phenylpiperidin-4-yl)methanesulfonamide
  N-(1-(8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl)piperidin-4-yl)pentanamide
  N(2),3-ethenoguanine (5-methyl-7-isopropyl-4,5-dihydroimidazo(2,1-b)purine)
  N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine Has associated genes Has associated diseases Has associated phenotype references
  N2-(4-(4-methylpiperazin-1-yl)phenyl)-N8-phenyl-9H-purine-2,8-diamine
  N-(2-(dimethylamino)ethyl)-N-methyl-4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)benzenesulfonamide
  N-((3-(3-9H-purin-6-yl)pyridin-2-ylamino)-2,4-difluorophenyl)furan-3-sulfonamide
  N-(3-((7H-purin-6-yl)thio)-4-hydroxynaphthalen-1-yl)-3,4-dimethoxybenzenesulfonamide
  N-(4-acetylphenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy)acetamide Has associated diseases
  N-(4-aminosulfonylphenyl)-2-morpholino-9H-purin-6-amine
  N-(4-cyanophenyl)-2-(4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-phenoxy)acetamide Has associated genes Has associated diseases Has associated phenotype references
  N-(4-methoxybenzyl)-N-methyl-9H-purine-2,6-diamine
  N-benzo(1,3)dioxol-5-yl-2-(5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy)-acetamide
  N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide Has associated genes Has associated diseases
  N-benzyl-N-methyl-2-(7,8-dihydro-7-(2-fluoroethyl)-8-oxo-2-phenyl-9H-purin-9-yl)acetamide
  N-benzyl-N-methyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide Has associated genes Has associated diseases
  N-benzylpiperidine-purine
  N-cyclopentyl-N-(4-methoxybenzyl)-9-methyl-9H-purine-2,6-diamine
  NPD15095
  NSC 45641
  NSC 51095
  NU6102 Has associated genes Has associated diseases
  olomoucine II Has associated genes Has associated diseases
  PH006 compound
  PP242 Has associated genes Has associated diseases Has associated phenotype references
  PR5-LL-CM01
  pumitepa
  purine Has associated phenotype references
  purine-6-sulfenic acid
  purine N-oxide
View node Purine Nucleosides Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references
View node Purine Nucleotides Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references
View node Purinones Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references
  purmorphamine Has associated genes Has associated diseases
  pyrimido(1,2-a)purin-10(3H)-one
  QS11 compound
  (R)-8-benzyl-2-cyclopentyl-7, 8-dihydro-4-propyl-1H-imidazo(2,1-i)purin-5(4H)-one hydrochloride
  rabacfosadine
  regadenoson
  Regulatory particle-Inhibiting Peptoid-1
  ribociclib Has associated genes Has associated diseases Has associated phenotype references
  Roscovitine Has associated genes Has associated diseases Has associated phenotype references
  RWJ-140998
  S 2242
  S-(6-purinyl)glutathione
View node Saxitoxin Has associated genes Has associated diseases Has associated phenotype references
  SB2602
  SHC004-221A1
View node Sildenafil Citrate Has associated genes Has associated diseases Has associated phenotype references
  SK 1899
  SKLB1028
  SKLB1206
  SKLB188
  SR-2890
  SR-3029
  StemRegenin 1 Has associated genes Has associated diseases Has associated phenotype references
  SV-030
  tegobuvir
View node Thioguanine Has associated genes Has associated diseases Has associated phenotype references
  trabodenoson
  UC-1V150
  UK-371,800
  VER6947
  VER7835
View node Adenine Has associated genes Has associated diseases Has associated phenotype references
  VS-5584
  WYE-354
  X-370 compound