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Chemical Purines

1–50 of 3,684 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1,3-dipropyl-8-cyclopentylxanthine vasodilation Glyburide 1,3-dipropyl-8-cyclopentylxanthine promotes the reaction [Glyburide results in decreased vasodilation] 1: Rattus norvegicus Ileum | Blood Vessels 1 gene: ADORA2A 1
2. 1,3-dipropyl-8-cyclopentylxanthine vasodilation Glucose 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [Glucose results in increased vasodilation] 1: Rattus norvegicus Jejunum | Blood Vessels 1 gene: ADORA2A 1
3. 1,7-dimethyluric acid exogenous drug catabolic process Caffeine | Quercetin [[Quercetin affects exogenous drug catabolic process] which affects the metabolism of Caffeine] which results in increased abundance of 1,7-dimethyluric acid 1: Homo sapiens Urine 1 gene: CYP2A6 1
4. 1,7-dimethylxanthine regulation of blood pressure 1,7-dimethylxanthine affects regulation of blood pressure 1: Homo sapiens Cardiovascular System   1
5. 1,7-dimethylxanthine exogenous drug catabolic process Caffeine | Quercetin [[Quercetin affects exogenous drug catabolic process] which affects the metabolism of Caffeine] which results in decreased abundance of 1,7-dimethylxanthine 1: Homo sapiens Plasma
2 genes: CYP1A2 | CYP2A6
1
6. 1,7-dimethylxanthine exogenous drug catabolic process Caffeine | Quercetin [[Quercetin affects exogenous drug catabolic process] which affects the metabolism of Caffeine] which results in decreased abundance of 1,7-dimethylxanthine 1: Homo sapiens Urine
2 genes: CYP1A2 | CYP2A6
1
7. 1,7-dimethylxanthine drug catabolic process Rifampin [Rifampin results in increased drug catabolic process] which results in increased chemical synthesis of 1,7-dimethylxanthine 1: Homo sapiens Hepatocytes | Cell Line, Tumor 1 gene: CYP1A2 1
8. 1,7-dimethylxanthine drug catabolic process Rifampin [Rifampin results in increased drug catabolic process] which results in increased chemical synthesis of 1,7-dimethylxanthine 1: Homo sapiens Hepatocytes | Cells, Cultured 1 gene: CYP1A2 1
9. 1,7-dimethylxanthine drug catabolic process Methylcholanthrene [Methylcholanthrene results in increased drug catabolic process] which results in increased chemical synthesis of 1,7-dimethylxanthine 1: Homo sapiens Hepatocytes | Spheroids, Cellular 1 gene: CYP1A2 1
10. 1-methyladenine DNA dealkylation involved in DNA repair ALKBH2 [ALKBH2 protein results in increased DNA dealkylation involved in DNA repair] which results in decreased abundance of 1-methyladenine 1: Homo sapiens     1
11. 1-methyladenine DNA dealkylation involved in DNA repair ALKBH3 [ALKBH3 protein results in increased DNA dealkylation involved in DNA repair] which results in decreased abundance of 1-methyladenine 1: Homo sapiens     1
12. 1-methyladenine oocyte maturation 1-methyladenine results in increased oocyte maturation 1: Asterias rubens Oocytes   1
13. 1-methyladenine oocyte maturation 4-bromophenacyl bromide 4-bromophenacyl bromide inhibits the reaction [1-methyladenine results in increased oocyte maturation] 1: Asterias rubens Oocytes   1
14. 1-methyladenine oocyte maturation Quinacrine Quinacrine inhibits the reaction [1-methyladenine results in increased oocyte maturation] 1: Asterias rubens Oocytes   1
15. 1-methyladenine oocyte maturation 4-bromophenacyl bromide 1-methyladenine inhibits the reaction [4-bromophenacyl bromide inhibits the reaction [1-methyladenine results in increased oocyte maturation]] 1: Asterias rubens Oocytes   1
16. 1-methyladenine oocyte maturation Quinacrine 1-methyladenine inhibits the reaction [Quinacrine inhibits the reaction [1-methyladenine results in increased oocyte maturation]] 1: Asterias rubens Oocytes   1
17. 1-methyladenine oocyte maturation Quercetin Quercetin inhibits the reaction [1-methyladenine results in increased oocyte maturation] 1: Asterias rubens Oocytes   1
18. 1-methyladenine oocyte maturation 5,8,11,14-Eicosatetraynoic Acid 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [1-methyladenine results in increased oocyte maturation] 1: Asterias rubens Oocytes   1
19. 1-methyladenine oocyte maturation Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [1-methyladenine results in increased oocyte maturation] 1: Asterias rubens Oocytes   1
20. 1-methylguanine DNA dealkylation involved in DNA repair ALKBH2 [ALKBH2 protein results in increased DNA dealkylation involved in DNA repair] which results in decreased abundance of 1-methylguanine 1: Homo sapiens     1
21. 1-methyluric acid exogenous drug catabolic process Caffeine | Quercetin [[Quercetin affects exogenous drug catabolic process] which affects the metabolism of Caffeine] which results in increased abundance of 1-methyluric acid 1: Homo sapiens Urine   1
22. 1-methylxanthine exogenous drug catabolic process Caffeine | Quercetin [[Quercetin affects exogenous drug catabolic process] which affects the metabolism of Caffeine] which results in decreased abundance of 1-methylxanthine 1: Homo sapiens Plasma 1 gene: CYP1A2 1
23. 1-methylxanthine exogenous drug catabolic process Caffeine | Quercetin [[Quercetin affects exogenous drug catabolic process] which affects the metabolism of Caffeine] which results in decreased abundance of 1-methylxanthine 1: Homo sapiens Urine 1 gene: CYP1A2 1
24. 1-propyl-8-(4-sulfophenyl)xanthine cell proliferation 1-propyl-8-(4-sulfophenyl)xanthine results in decreased cell proliferation 1: Mus musculus Skin | Cell Line, Tumor 1 gene: FGF2 1
25. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide eosinophil extravasation Formaldehyde | Ovalbumin 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased eosinophil extravasation] 1: Mus musculus Lung   1
26. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide neutrophil extravasation Formaldehyde | Ovalbumin 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased neutrophil extravasation] 1: Mus musculus Lung   1
27. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide interleukin-4 secretion Formaldehyde | Ovalbumin 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased interleukin-4 secretion] 1: Mus musculus Lung   1
28. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide interleukin-1 beta secretion Formaldehyde | Ovalbumin 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [[Ovalbumin co-treated with Formaldehyde] results in increased interleukin-1 beta secretion] 1: Mus musculus Lung   1
29. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide necrotic cell death carvacrol | irinotecan 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased necrotic cell death]] 1: Mus musculus Jejunum   1
30. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inflammatory response carvacrol | irinotecan 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased inflammatory response]] 1: Mus musculus Jejunum
5 genes: IL13 | IL1B | IL5 | TAC1 | TNF
1
31. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide glutathione biosynthetic process carvacrol | irinotecan 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in decreased glutathione biosynthetic process]] 1: Mus musculus Jejunum   1
32. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide lipid catabolic process carvacrol | irinotecan 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased lipid catabolic process]] 1: Mus musculus Jejunum   1
33. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide nitric oxide biosynthetic process carvacrol | irinotecan 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [carvacrol inhibits the reaction [irinotecan results in increased nitric oxide biosynthetic process]] 1: Mus musculus Jejunum   1
34. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide positive regulation of cytosolic calcium ion concentration allyl isothiocyanate 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [allyl isothiocyanate results in increased positive regulation of cytosolic calcium ion concentration] 1: Rattus norvegicus HEK293 Cells
3 genes: CXCL1 | IL1B | TAC1
1
35. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide transepithelial transport allyl isothiocyanate 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [allyl isothiocyanate results in increased transepithelial transport] 1: Mus musculus Colon | Intestinal Mucosa   1
36. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide swimming behavior Particulate Matter 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [Particulate Matter affects swimming behavior] 1: Danio rerio     1
37. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide swimming behavior Vehicle Emissions 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [Vehicle Emissions affects swimming behavior] 1: Danio rerio     1
38. 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide swimming behavior Acrolein 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [Acrolein affects swimming behavior] 1: Danio rerio     1
39. 2',3'-dialdehyde ATP cell death 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate | P2RX7 2',3'-dialdehyde ATP inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate binds to and results in increased activity of P2RX7 protein] which results in increased cell death] 1: Rattus norvegicus Retinal Ganglion Cells | Cells, Cultured 1 gene: P2RX7 1
40. 2',3'-dialdehyde ATP vesicle budding from membrane Toluene 2,4-Diisocyanate 2',3'-dialdehyde ATP inhibits the reaction [Toluene 2,4-Diisocyanate results in increased vesicle budding from membrane] 1: Homo sapiens Lung | Epithelial Cells | Cell Line, Tumor 1 gene: P2RX7 1
41. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine regulation of blood pressure 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased regulation of blood pressure 1: Rattus norvegicus Cardiovascular System
4 genes: EPHX2 | LEP | NPPA | REN
1
42. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine regulation of heart rate 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased regulation of heart rate 1: Rattus norvegicus Heart   1
43. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine regulation of heart rate Atenolol Atenolol inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased regulation of heart rate] 1: Rattus norvegicus Heart   1
44. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine apoptotic process 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased apoptotic process 1: Homo sapiens Neutrophils
3 genes: ADORA2A | PRKCE | TNF
1
45. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine apoptotic process 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased apoptotic process 1: Homo sapiens Eosinophils
3 genes: ADORA2A | PRKCE | TNF
1
46. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine apoptotic process 8-(4-sulfophenyl)theophylline 8-(4-sulfophenyl)theophylline inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased apoptotic process] 1: Homo sapiens Neutrophils
3 genes: ADORA2A | PRKCE | TNF
1
47. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine regulation of circadian rhythm 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased regulation of circadian rhythm 1: Homo sapiens Monocytes | Cell Line
2 genes: NR1D1 | PER2
1
48. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine negative regulation of vasoconstriction EPHX2 EPHX2 gene mutant form promotes the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased negative regulation of vasoconstriction] 1: Mus musculus Aorta
2 genes: LEP | MMP2
1
49. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine negative regulation of vasoconstriction 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased negative regulation of vasoconstriction 1: Mus musculus Aorta
2 genes: LEP | MMP2
1
50. 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine negative regulation of vasoconstriction 14,15-eicosa-5-enoic acid 14,15-eicosa-5-enoic acid inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased negative regulation of vasoconstriction] 1: Mus musculus Aorta
2 genes: LEP | MMP2
1
1–50 of 3,684 results.