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Chemical Purinones

These are exposure studies associated with the chemical and all of its children.

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1–10 of 10 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Huang YF, et al. (2017). Our results support a role for exposure to 4-nonylphenol and bisphenol A and possibly inflammation in increasing oxidative/nitrative stress and decreasing antioxidant activity during pregnancy. 4-nonylphenol | bisphenol A Pregnant females Taiwan, Province of China blood | blood, cord | urine 4-nonylphenol | 8-epi-prostaglandin F2alpha | 8-nitroguanine | 8-oxo-7-hydrodeoxyguanosine | bisphenol A | GPX1 | TNF Details negative regulation of glutathione peroxidase activity | tumor necrosis factor production
2. Hiraku Y, et al. (2014). We demonstrate that 8-nitroguanine formation is associated with asbestos content in human lung tissues, raising the possibility that it might serve as a biomarker to evaluate asbestos exposure and carcinogenic risk. Asbestos, Amphibole | Asbestos Controls for disease:Mesothelioma, Malignant | Subjects with disease:Mesothelioma, Malignant Japan lung 8-nitroguanine | APEX1 | Asbestos, Amphibole | Asbestos, Serpentine Details
3. Wesselink AK, et al. (2016). Pregnancy Study Online (PRESTO) Total caffeine intake among males, but not females, was associated with fecundability, although the association was not monotonic; with respect to individual beverages, caffeinated black tea was associated with slight reductions among females, and caffeinated soda and energy drink were associated with reduced fecundability among males. diet | sex Caffeine Study subjects Canada|United States beverage, caffeinated | tea, black Caffeine Details female pregnancy
4. Go YM, et al. (2015). We examined quantification strategies to enhance the usefulness of high-resolution metabolomics data for cumulative exposome research; the results provide a simple reference standardization protocol in which individual chemical concentrations are estimated by comparison to a concurrently analyzed, pooled reference sample with known chemical concentrations. Caffeine | Chlorobenzoates | chlorsulfuron | Cotinine | Fyrol PCF | hippuric acid | meobal | octylphenol | pirimicarb | Styrene Study subjects United States plasma Caffeine | Chlorobenzoates | chlorsulfuron | Cotinine | Fyrol PCF | hippuric acid | meobal | octylphenol | pirimicarb | Styrene Details
5. Yang H, et al. (2015). Male Reproductive Health in Chongqing College students (MARHCS) The primary objectives of the MARHCS study are to investigate the associations of male reproductive health in young adults with sociopsychobehavioral factors, as well as changes of environmental exposure due to the relocation from rural campus (in University Town) to metro-campus (in central downtown). diet | tobacco Caffeine | Tobacco Smoke Pollution Study subjects China semen Details spermatogenesis | sperm motility
6. Kataria A, et al. (2015). National Health and Nutrition Examination Survey (NHANES) Perfluoroalkyl acids are associated with a reduction in kidney function and increased uric acid levels in otherwise healthy adolescents. Fluorocarbons Children United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid | Uric Acid Details glomerular filtration
7. Kasperczyk S, et al. (2014). We examined the effects of N-acetylcysteine administration on the non-enzymatic defense systems (e.g., uric acid, albumin, bilirubin and alpha-tocopherol) in male workers exposed to lead, over a 12 week study period. Lead Workers Poland blood ALB | alpha-Tocopherol | Bilirubin | Lead | Lipid Peroxides | Uric Acid | zinc protoporphyrin Details
8. Schreinemachers DM, et al. (2015). National Health and Nutrition Examination Survey (NHANES) This study investigated associations between urinary perchlorate and biomarkers of oxidative stress and iron homeostasis, including blood urea nitrogen, lymphocyte counts, serum uric acid, serum iron, and red blood cell counts. perchlorate Study subjects United States serum | urine Iron | perchlorate | Uric Acid Details erythrocyte homeostasis | iron ion homeostasis | lymphocyte homeostasis
9. Steenland K, et al. (2010). C8 Health Project (C8HP) Higher serum levels of perfluorooctanoic acid were associated with a higher prevalence of hyperuricemia, but the limitations of cross-sectional data and the possibility of noncausal mechanisms prohibit conclusions regarding causality. perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid | Uric Acid Details Hyperuricemia
10. Shankar A, et al. (2011). National Health and Nutrition Examination Survey (NHANES) Our results demonstrate that elevated levels of perfluoroalkyl chemicals are associated with hyperuricemia even at low perfluoroalkyl chemical exposure levels as seen in a representative, multiethnic sample of US adults. perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum Uric Acid Details Hyperuricemia
1–10 of 10 results.