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Chemical Pyridines

1–50 of 5,477 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid microtubule motor activity Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased microtubule motor activity] 1: Mus musculus Coronary Vessels | Muscle Cells   1
2. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid autophagosome maturation Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased autophagosome maturation] 1: Mus musculus Coronary Vessels | Muscle Cells   1
3. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction NAADP 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog affects the reaction [NAADP results in increased acrosome reaction] 1: Mus musculus Spermatozoa   1
4. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog results in increased acrosome reaction 1: Mus musculus Spermatozoa   1
5. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene cell proliferation 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased cell proliferation 1: Mus musculus Liver | Hepatocytes
88 genes: ACHE | ACVR2B | AKT1 | AURKB | AXIN2 | BAD | BAK1 | BAX | BCL2L1 | BRCA2 | BUB1 | BUB1B | CDC25C | CDK1 | CDK4 | CENPF | CFB | CKS1B | COL4A3 | COPS2 | CREG1 | CTNNB1 | CXCL1 | CYP1A1 | DDIT4 | DLGAP5 | EGFR | EMP1 | EMP2 | ENTPD5 | ERBB2 | FAM83D | FPGS | GAB1 | GAS6 | GLUL | GNAT1 | GNL3 | GSK3B | HGF | IGF1 | IL15RA | IL18 | IRF2 | KIF15 | KIF2C | LRP1 | LY6E | MAS1 | MCM10 | MCM7 | MET | MKI67 | MOB1A | MT3 | MYC | NR6A1 | NRG1 | PCNA | PDK1 | PDXK | PDZK1 | PES1 | PICALM | PIM1 | PLK1 | POLA1 | PRDX1 | PRG4 | PROK1 | PTEN | RAF1 | RBBP7 | SKP2 | STAT3 | STIL | TACC2 | TCF19 | TGFA | THPO | TNF | TOP2A | TPX2 | TRAIP | UHRF1 | YAP1 | ZFP36L1 | ZPR1
1
6. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene cell proliferation Pregnenolone Carbonitrile Pregnenolone Carbonitrile promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased cell proliferation] 1: Mus musculus Liver | Hepatocytes
88 genes: ACHE | ACVR2B | AKT1 | AURKB | AXIN2 | BAD | BAK1 | BAX | BCL2L1 | BRCA2 | BUB1 | BUB1B | CDC25C | CDK1 | CDK4 | CENPF | CFB | CKS1B | COL4A3 | COPS2 | CREG1 | CTNNB1 | CXCL1 | CYP1A1 | DDIT4 | DLGAP5 | EGFR | EMP1 | EMP2 | ENTPD5 | ERBB2 | FAM83D | FPGS | GAB1 | GAS6 | GLUL | GNAT1 | GNL3 | GSK3B | HGF | IGF1 | IL15RA | IL18 | IRF2 | KIF15 | KIF2C | LRP1 | LY6E | MAS1 | MCM10 | MCM7 | MET | MKI67 | MOB1A | MT3 | MYC | NR6A1 | NRG1 | PCNA | PDK1 | PDXK | PDZK1 | PES1 | PICALM | PIM1 | PLK1 | POLA1 | PRDX1 | PRG4 | PROK1 | PTEN | RAF1 | RBBP7 | SKP2 | STAT3 | STIL | TACC2 | TCF19 | TGFA | THPO | TNF | TOP2A | TPX2 | TRAIP | UHRF1 | YAP1 | ZFP36L1 | ZPR1
1
7. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene regulation of peroxisome proliferator activated receptor signaling pathway 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects regulation of peroxisome proliferator activated receptor signaling pathway 1: Mus musculus Liver   1
8. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased lipid biosynthetic process 1: Mus musculus Liver
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
9. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process NR1I3 NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased lipid biosynthetic process] 1: Mus musculus Liver
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
10. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene triglyceride biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased triglyceride biosynthetic process 1: Mus musculus Liver
5 genes: GPAM | LPIN1 | LPIN2 | LPL | PNPLA3
1
11. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene triglyceride biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased triglyceride biosynthetic process 1: Mus musculus Plasma
5 genes: GPAM | LPIN1 | LPIN2 | LPL | PNPLA3
1
12. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene gluconeogenesis 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased gluconeogenesis 1: Mus musculus Plasma
11 genes: FBP1 | G6PC | GOT1 | PCK1 | PCX | PER2 | PGK1 | PGM1 | PPARGC1A | SDS | SLC25A10
1
13. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene triglyceride biosynthetic process NR1I3 NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased triglyceride biosynthetic process] 1: Mus musculus Plasma
5 genes: GPAM | LPIN1 | LPIN2 | LPL | PNPLA3
1
14. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene gluconeogenesis NR1I3 NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased gluconeogenesis] 1: Mus musculus Plasma
11 genes: FBP1 | G6PC | GOT1 | PCK1 | PCX | PER2 | PGK1 | PGM1 | PPARGC1A | SDS | SLC25A10
1
15. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process NR1I3 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the reaction [NR1I3 protein affects lipid biosynthetic process] 1: Mus musculus Liver
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
16. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene DNA biosynthetic process HGF | IL6 | TGFA 1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [[IL6 protein co-treated with HGF protein co-treated with TGFA protein] results in increased DNA biosynthetic process] 1: Homo sapiens Hepatocytes | Cells, Cultured
7 genes: CENPF | CTGF | DNTT | LIG1 | POLA1 | POLE | TERT
1
17. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased lipid biosynthetic process 1: Mus musculus Mammary Glands, Animal
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
18. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene gluconeogenesis 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased gluconeogenesis 1: Mus musculus Mammary Glands, Animal
11 genes: FBP1 | G6PC | GOT1 | PCK1 | PCX | PER2 | PGK1 | PGM1 | PPARGC1A | SDS | SLC25A10
1
19. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene collagen biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased collagen biosynthetic process 1: Mus musculus Mammary Glands, Animal | Adipose Tissue 1 gene: COL1A1 1
20. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene regulation of chromatin assembly or disassembly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects regulation of chromatin assembly or disassembly 1: Mus musculus Liver   1
21. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene regulation of chromatin-mediated maintenance of transcription 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects regulation of chromatin-mediated maintenance of transcription 1: Mus musculus Liver 1 gene: CTNNB1 1
22. 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide neuron death cyclohexyl methylphosphonofluoridate 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide inhibits the reaction [cyclohexyl methylphosphonofluoridate results in increased neuron death] 1: Rattus norvegicus   1 gene: ACHE 1
23. 1,4-dihydropyridine vasodilation 1,4-dihydropyridine analog results in increased vasodilation 2: Homo sapiens | unidentified monkey Brain | Blood Vessels 1 gene: CFTR 1
24. 1,4-dihydropyridine vasodilation 1,4-dihydropyridine results in increased vasodilation 1: Canis lupus familiaris Brain | Blood Vessels 1 gene: CFTR 1
25. 1,4-dihydropyridine vasodilation 1,4-dihydropyridine results in increased vasodilation 1: Canis lupus familiaris Heart | Blood Vessels 1 gene: CFTR 1
26. 1,4-dihydropyridine positive regulation of cell death 1,4-dihydropyridine results in increased positive regulation of cell death 1: Homo sapiens HEK293 Cells   1
27. 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide membrane lipid catabolic process Atropine | Malathion [1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Malathion results in increased membrane lipid catabolic process] 1: Mus musculus Prefrontal Cortex   1
28. 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid cell death 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid results in increased cell death 1: Mus musculus Spinal Cord | Neurons   1
29. 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid cell death IL1A IL1A protein affects the reaction [1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid results in increased cell death] 1: Mus musculus Spinal Cord | Neurons   1
30. 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid cell death 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid results in decreased cell death 1: Mus musculus Spinal Cord | Neurons   1
31. 2,2',2''-terpyridine positive regulation of cell death Chlorine | Palladium | Saccharin [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
32. 2,2',2''-terpyridine apoptotic chromosome condensation Chlorine | Palladium | Saccharin [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased apoptotic chromosome condensation 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
33. 2,2',2''-terpyridine apoptotic chromosome condensation Chlorine | Niclosamide | Palladium | Saccharin Niclosamide promotes the reaction [[[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased apoptotic chromosome condensation] 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
34. 2,2',2''-terpyridine positive regulation of cell death Chlorine | Niclosamide | Palladium | Saccharin Niclosamide promotes the reaction [[[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased positive regulation of cell death] 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
35. 2,2',2''-terpyridine activation of cysteine-type endopeptidase activity involved in apoptotic process Chlorine | Niclosamide | Palladium | Saccharin [Niclosamide co-treated with [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin]] results in increased activation of cysteine-type endopeptidase activity involved in apoptotic process 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
36. 2,2',2''-terpyridine activation of cysteine-type endopeptidase activity involved in apoptotic process Chlorine | KRT18 | Niclosamide | Palladium | Saccharin [[Niclosamide co-treated with [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin]] results in increased activation of cysteine-type endopeptidase activity involved in apoptotic process] which results in increased cleavage of KRT18 protein 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
37. 2-(2-aminoethyl)pyridine regulation of blood pressure 2-(2-aminoethyl)pyridine results in decreased regulation of blood pressure 1: Canis lupus familiaris Blood Vessels 1 gene: SOD1 1
38. 2-(2-aminoethyl)pyridine regulation of blood pressure Penicillamine Penicillamine promotes the reaction [2-(2-aminoethyl)pyridine results in decreased regulation of blood pressure] 1: Canis lupus familiaris Blood Vessels 1 gene: SOD1 1
39. 2,2'-dipyridyl disulfide apoptotic process 2,2'-dipyridyl disulfide results in increased apoptotic process 1: Rattus norvegicus Embryonic Structures | Prosencephalon | Neurons | Cells, Cultured
4 genes: CASP3 | CASP9 | MAPK1 | MAPK3
1
40. 2,2'-dipyridyl disulfide apoptotic process Tetraethylammonium Tetraethylammonium inhibits the reaction [2,2'-dipyridyl disulfide results in increased apoptotic process] 1: Rattus norvegicus Embryonic Structures | Prosencephalon | Neurons | Cells, Cultured
4 genes: CASP3 | CASP9 | MAPK1 | MAPK3
1
41. 2,2'-dipyridyl disulfide apoptotic process Potassium Potassium inhibits the reaction [2,2'-dipyridyl disulfide results in increased apoptotic process] 1: Rattus norvegicus Embryonic Structures | Prosencephalon | Neurons | Cells, Cultured
4 genes: CASP3 | CASP9 | MAPK1 | MAPK3
1
42. 2,2'-dipyridyl disulfide apoptotic process SB 239063 SB 239063 inhibits the reaction [2,2'-dipyridyl disulfide results in increased apoptotic process] 1: Rattus norvegicus Embryonic Structures | Prosencephalon | Neurons | Cells, Cultured
4 genes: CASP3 | CASP9 | MAPK1 | MAPK3
1
43. 2,2'-dipyridyl disulfide apoptotic process Niacinamide Niacinamide inhibits the reaction [2,2'-dipyridyl disulfide results in increased apoptotic process] 1: Rattus norvegicus Embryonic Structures | Prosencephalon | Neurons | Cells, Cultured
4 genes: CASP3 | CASP9 | MAPK1 | MAPK3
1
44. 2,2'-dipyridyl disulfide apoptotic process benzamide benzamide inhibits the reaction [2,2'-dipyridyl disulfide results in increased apoptotic process] 1: Rattus norvegicus Embryonic Structures | Prosencephalon | Neurons | Cells, Cultured
4 genes: CASP3 | CASP9 | MAPK1 | MAPK3
1
45. 2,2'-dipyridyl disulfide reactive oxygen species biosynthetic process 2,2'-dipyridyl disulfide results in increased reactive oxygen species biosynthetic process 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
46. 2,2'-dipyridyl disulfide reactive oxygen species biosynthetic process polydatin polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased reactive oxygen species biosynthetic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
47. 2,2'-dipyridyl disulfide lipid catabolic process 2,2'-dipyridyl disulfide results in increased lipid catabolic process 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
48. 2,2'-dipyridyl disulfide lipid catabolic process polydatin polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased lipid catabolic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
49. 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate apoptotic process 2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
50. 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate calcium-mediated signaling 2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide results in increased calcium-mediated signaling] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
1–50 of 5,477 results.