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Chemical Pyridines

1–50 of 5,697 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis perfluorooctane sulfonic acid 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [perfluorooctane sulfonic acid affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
2. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis Dibutyl Phthalate 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [Dibutyl Phthalate affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
3. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis Diethylhexyl Phthalate 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [Diethylhexyl Phthalate affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
4. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis 2,2',3,5',6-pentachlorobiphenyl 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [2,2',3,5',6-pentachlorobiphenyl affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
5. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis Chlorpyrifos 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [Chlorpyrifos affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
6. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis 2,2',4,4'-tetrabromodiphenyl ether 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
7. 1,1'-diheptyl-4,4'-bipyridinium calcium ion homeostasis 6-OH-BDE-47 1,1'-diheptyl-4,4'-bipyridinium inhibits the reaction [6-OH-BDE-47 affects calcium ion homeostasis] 1: Rattus norvegicus Cerebral Cortex | Microsomes   1
8. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid microtubule motor activity Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased microtubule motor activity] 1: Mus musculus Coronary Vessels | Muscle Cells   1
9. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid autophagosome maturation Glucose 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [Glucose results in increased autophagosome maturation] 1: Mus musculus Coronary Vessels | Muscle Cells   1
10. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction NAADP 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog affects the reaction [NAADP results in increased acrosome reaction] 1: Mus musculus Spermatozoa   1
11. 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid acrosome reaction 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid analog results in increased acrosome reaction 1: Mus musculus Spermatozoa   1
12. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene cell proliferation 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased cell proliferation 1: Mus musculus Liver | Hepatocytes
88 genes: ACHE | ACVR2B | AKT1 | AURKB | AXIN2 | BAD | BAK1 | BAX | BCL2L1 | BRCA2 | BUB1 | BUB1B | CCN1 | CDC25C | CDK1 | CDK4 | CENPF | CFB | CKS1B | COL4A3 | COPS2 | CREG1 | CTNNB1 | CXCL1 | CYP1A1 | DDIT4 | DLGAP5 | EGFR | EMP1 | EMP2 | ENTPD5 | ERBB2 | FAM83D | FPGS | GAB1 | GAS6 | GLUL | GNAT1 | GNL3 | GSK3B | HGF | IGF1 | IL15RA | IL18 | IRF2 | KIF15 | KIF2C | LRP1 | LY6E | MAS1 | MCM10 | MCM7 | MET | MKI67 | MOB1A | MT3 | MYC | NR6A1 | NRG1 | PCNA | PDK1 | PDXK | PDZK1 | PES1 | PICALM | PIM1 | PLK1 | POLA1 | PRDX1 | PRG4 | PROK1 | PTEN | RAF1 | RBBP7 | SKP2 | STAT3 | STIL | TACC2 | TCF19 | TGFA | THPO | TOP2A | TPX2 | TRAIP | UHRF1 | YAP1 | ZFP36L1 | ZPR1
1
13. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene cell proliferation Pregnenolone Carbonitrile Pregnenolone Carbonitrile promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased cell proliferation] 1: Mus musculus Liver | Hepatocytes
88 genes: ACHE | ACVR2B | AKT1 | AURKB | AXIN2 | BAD | BAK1 | BAX | BCL2L1 | BRCA2 | BUB1 | BUB1B | CCN1 | CDC25C | CDK1 | CDK4 | CENPF | CFB | CKS1B | COL4A3 | COPS2 | CREG1 | CTNNB1 | CXCL1 | CYP1A1 | DDIT4 | DLGAP5 | EGFR | EMP1 | EMP2 | ENTPD5 | ERBB2 | FAM83D | FPGS | GAB1 | GAS6 | GLUL | GNAT1 | GNL3 | GSK3B | HGF | IGF1 | IL15RA | IL18 | IRF2 | KIF15 | KIF2C | LRP1 | LY6E | MAS1 | MCM10 | MCM7 | MET | MKI67 | MOB1A | MT3 | MYC | NR6A1 | NRG1 | PCNA | PDK1 | PDXK | PDZK1 | PES1 | PICALM | PIM1 | PLK1 | POLA1 | PRDX1 | PRG4 | PROK1 | PTEN | RAF1 | RBBP7 | SKP2 | STAT3 | STIL | TACC2 | TCF19 | TGFA | THPO | TOP2A | TPX2 | TRAIP | UHRF1 | YAP1 | ZFP36L1 | ZPR1
1
14. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene regulation of peroxisome proliferator activated receptor signaling pathway 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects regulation of peroxisome proliferator activated receptor signaling pathway 1: Mus musculus Liver   1
15. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased lipid biosynthetic process 1: Mus musculus Liver
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
16. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process NR1I3 NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased lipid biosynthetic process] 1: Mus musculus Liver
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
17. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene triglyceride biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased triglyceride biosynthetic process 1: Mus musculus Liver
5 genes: GPAM | LPIN1 | LPIN2 | LPL | PNPLA3
1
18. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene triglyceride biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased triglyceride biosynthetic process 1: Mus musculus Plasma
5 genes: GPAM | LPIN1 | LPIN2 | LPL | PNPLA3
1
19. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene gluconeogenesis 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased gluconeogenesis 1: Mus musculus Plasma
11 genes: FBP1 | G6PC | GOT1 | PCK1 | PCX | PER2 | PGK1 | PGM1 | PPARGC1A | SDS | SLC25A10
1
20. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene triglyceride biosynthetic process NR1I3 NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased triglyceride biosynthetic process] 1: Mus musculus Plasma
5 genes: GPAM | LPIN1 | LPIN2 | LPL | PNPLA3
1
21. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene gluconeogenesis NR1I3 NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased gluconeogenesis] 1: Mus musculus Plasma
11 genes: FBP1 | G6PC | GOT1 | PCK1 | PCX | PER2 | PGK1 | PGM1 | PPARGC1A | SDS | SLC25A10
1
22. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process NR1I3 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the reaction [NR1I3 protein affects lipid biosynthetic process] 1: Mus musculus Liver
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
23. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene DNA biosynthetic process HGF | IL6 | TGFA 1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [[IL6 protein co-treated with HGF protein co-treated with TGFA protein] results in increased DNA biosynthetic process] 1: Homo sapiens Hepatocytes | Cells, Cultured
7 genes: CCN2 | CENPF | DNTT | LIG1 | POLA1 | POLE | TERT
1
24. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene lipid biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased lipid biosynthetic process 1: Mus musculus Mammary Glands, Animal
8 genes: ACSS2 | ENHO | FASN | FDFT1 | MSMO1 | SC5D | SCD1 | SREBF1
1
25. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene gluconeogenesis 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased gluconeogenesis 1: Mus musculus Mammary Glands, Animal
11 genes: FBP1 | G6PC | GOT1 | PCK1 | PCX | PER2 | PGK1 | PGM1 | PPARGC1A | SDS | SLC25A10
1
26. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene collagen biosynthetic process 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased collagen biosynthetic process 1: Mus musculus Mammary Glands, Animal | Adipose Tissue 1 gene: COL1A1 1
27. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene regulation of chromatin assembly or disassembly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects regulation of chromatin assembly or disassembly 1: Mus musculus Liver   1
28. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene regulation of chromatin-mediated maintenance of transcription 1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects regulation of chromatin-mediated maintenance of transcription 1: Mus musculus Liver 1 gene: CTNNB1 1
29. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene positive regulation of hepatocyte proliferation enilconazole enilconazole promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased positive regulation of hepatocyte proliferation] 1: Mus musculus Liver | Hepatocytes
2 genes: ITPR1 | MED1
1
30. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene positive regulation of hepatocyte proliferation 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased positive regulation of hepatocyte proliferation 1: Mus musculus Liver | Hepatocytes
2 genes: ITPR1 | MED1
1
31. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene positive regulation of cell proliferation YAP1 YAP1 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased positive regulation of cell proliferation] 1: Mus musculus Hepatocytes
93 genes: ACER3 | AGT | AKT1 | AVPR1A | BCL2L1 | BIRC5 | BMP5 | CALCRL | CALR | CCN2 | CCND1 | CDC20 | CDK2 | CDK4 | CDKN1B | CLCF1 | COL18A1 | CTNNB1 | CXCL12 | CXCR3 | EGFR | EMP2 | ERBB2 | F2R | FGF21 | FGFR4 | FN1 | FOXM1 | GAS1 | GCNT2 | HGF | HMGCR | HMX2 | HSP90AA1 | IGF1 | IHH | IL11RA1 | IL18 | IL1B | IL6 | IL6RA | IRS1 | ITGB1 | JAK2 | JUN | KIF14 | KIF20B | KITL | KLF5 | LAMC2 | LIFR | MAPK1 | MAS1 | MDM2 | MED1 | MFGE8 | MIB1 | MLXIPL | MYC | NAMPT | NDUFAF4 | NLGN2 | NOLC1 | NOP2 | NRG1 | ODC1 | PDGFA | PRC1 | PRKACA | PRKCZ | PROK1 | PRTN3 | PTEN | PTGS2 | PTK2 | PTK2B | RAD51B | RARA | RARB | ROGDI | RRM2 | SLC25A33 | SSR1 | ST8SIA1 | STAT3 | TGFA | TGFBR2 | THPO | TNF | TSC22D1 | TTK | WNT5A | YAP1
1
32. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene positive regulation of cell proliferation Verteporfin Verteporfin inhibits the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased positive regulation of cell proliferation] 1: Mus musculus Hepatocytes
93 genes: ACER3 | AGT | AKT1 | AVPR1A | BCL2L1 | BIRC5 | BMP5 | CALCRL | CALR | CCN2 | CCND1 | CDC20 | CDK2 | CDK4 | CDKN1B | CLCF1 | COL18A1 | CTNNB1 | CXCL12 | CXCR3 | EGFR | EMP2 | ERBB2 | F2R | FGF21 | FGFR4 | FN1 | FOXM1 | GAS1 | GCNT2 | HGF | HMGCR | HMX2 | HSP90AA1 | IGF1 | IHH | IL11RA1 | IL18 | IL1B | IL6 | IL6RA | IRS1 | ITGB1 | JAK2 | JUN | KIF14 | KIF20B | KITL | KLF5 | LAMC2 | LIFR | MAPK1 | MAS1 | MDM2 | MED1 | MFGE8 | MIB1 | MLXIPL | MYC | NAMPT | NDUFAF4 | NLGN2 | NOLC1 | NOP2 | NRG1 | ODC1 | PDGFA | PRC1 | PRKACA | PRKCZ | PROK1 | PRTN3 | PTEN | PTGS2 | PTK2 | PTK2B | RAD51B | RARA | RARB | ROGDI | RRM2 | SLC25A33 | SSR1 | ST8SIA1 | STAT3 | TGFA | TGFBR2 | THPO | TNF | TSC22D1 | TTK | WNT5A | YAP1
1
33. 1,4-bis(2-(3,5-dichloropyridyloxy))benzene positive regulation of cell proliferation 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased positive regulation of cell proliferation 1: Mus musculus Liver | Hepatocytes
93 genes: ACER3 | AGT | AKT1 | AVPR1A | BCL2L1 | BIRC5 | BMP5 | CALCRL | CALR | CCN2 | CCND1 | CDC20 | CDK2 | CDK4 | CDKN1B | CLCF1 | COL18A1 | CTNNB1 | CXCL12 | CXCR3 | EGFR | EMP2 | ERBB2 | F2R | FGF21 | FGFR4 | FN1 | FOXM1 | GAS1 | GCNT2 | HGF | HMGCR | HMX2 | HSP90AA1 | IGF1 | IHH | IL11RA1 | IL18 | IL1B | IL6 | IL6RA | IRS1 | ITGB1 | JAK2 | JUN | KIF14 | KIF20B | KITL | KLF5 | LAMC2 | LIFR | MAPK1 | MAS1 | MDM2 | MED1 | MFGE8 | MIB1 | MLXIPL | MYC | NAMPT | NDUFAF4 | NLGN2 | NOLC1 | NOP2 | NRG1 | ODC1 | PDGFA | PRC1 | PRKACA | PRKCZ | PROK1 | PRTN3 | PTEN | PTGS2 | PTK2 | PTK2B | RAD51B | RARA | RARB | ROGDI | RRM2 | SLC25A33 | SSR1 | ST8SIA1 | STAT3 | TGFA | TGFBR2 | THPO | TNF | TSC22D1 | TTK | WNT5A | YAP1
1
34. 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide neuron death cyclohexyl methylphosphonofluoridate 1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide inhibits the reaction [cyclohexyl methylphosphonofluoridate results in increased neuron death] 1: Rattus norvegicus   1 gene: ACHE 1
35. 1,4-dihydropyridine vasodilation 1,4-dihydropyridine analog results in increased vasodilation 2: Homo sapiens | unidentified monkey Brain | Blood Vessels 1 gene: CFTR 1
36. 1,4-dihydropyridine vasodilation 1,4-dihydropyridine results in increased vasodilation 1: Canis lupus familiaris Brain | Blood Vessels 1 gene: CFTR 1
37. 1,4-dihydropyridine vasodilation 1,4-dihydropyridine results in increased vasodilation 1: Canis lupus familiaris Heart | Blood Vessels 1 gene: CFTR 1
38. 1,4-dihydropyridine positive regulation of cell death 1,4-dihydropyridine results in increased positive regulation of cell death 1: Homo sapiens HEK293 Cells   1
39. 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide membrane lipid catabolic process Atropine | Malathion [1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Malathion results in increased membrane lipid catabolic process] 1: Mus musculus Prefrontal Cortex   1
40. 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid cell death 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid results in increased cell death 1: Mus musculus Spinal Cord | Neurons   1
41. 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid cell death IL1A IL1A protein affects the reaction [1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid results in increased cell death] 1: Mus musculus Spinal Cord | Neurons   1
42. 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid cell death 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid results in decreased cell death 1: Mus musculus Spinal Cord | Neurons   1
43. 2,2',2''-terpyridine positive regulation of cell death Chlorine | Palladium | Saccharin [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
44. 2,2',2''-terpyridine apoptotic chromosome condensation Chlorine | Palladium | Saccharin [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased apoptotic chromosome condensation 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
45. 2,2',2''-terpyridine apoptotic chromosome condensation Chlorine | Niclosamide | Palladium | Saccharin Niclosamide promotes the reaction [[[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased apoptotic chromosome condensation] 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
46. 2,2',2''-terpyridine positive regulation of cell death Chlorine | Niclosamide | Palladium | Saccharin Niclosamide promotes the reaction [[[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin] which results in increased positive regulation of cell death] 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
47. 2,2',2''-terpyridine activation of cysteine-type endopeptidase activity involved in apoptotic process Chlorine | Niclosamide | Palladium | Saccharin [Niclosamide co-treated with [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin]] results in increased activation of cysteine-type endopeptidase activity involved in apoptotic process 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
48. 2,2',2''-terpyridine activation of cysteine-type endopeptidase activity involved in apoptotic process Chlorine | KRT18 | Niclosamide | Palladium | Saccharin [[Niclosamide co-treated with [[2,2',2''-terpyridine binds to Palladium binds to Chlorine] which binds to Saccharin]] results in increased activation of cysteine-type endopeptidase activity involved in apoptotic process] which results in increased cleavage of KRT18 protein 1: Homo sapiens MCF-7 Cells | Neoplastic Stem Cells   1
49. 2-(2-aminoethyl)pyridine regulation of blood pressure 2-(2-aminoethyl)pyridine results in decreased regulation of blood pressure 1: Canis lupus familiaris Blood Vessels 1 gene: SOD1 1
50. 2-(2-aminoethyl)pyridine regulation of blood pressure Penicillamine Penicillamine promotes the reaction [2-(2-aminoethyl)pyridine results in decreased regulation of blood pressure] 1: Canis lupus familiaris Blood Vessels 1 gene: SOD1 1
1–50 of 5,697 results.