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Chemical Pyrroles

1–50 of 1,706 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1-(propoxymethyl)maleimide apoptotic process WRN [1-(propoxymethyl)maleimide results in decreased activity of WRN protein] which results in increased apoptotic process 1: Homo sapiens HeLa Cells   1
2. 1-(propoxymethyl)maleimide cell proliferation 1-(propoxymethyl)maleimide results in decreased cell proliferation 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
3. 1-(propoxymethyl)maleimide cell proliferation WRN [1-(propoxymethyl)maleimide results in decreased activity of WRN protein] which results in decreased cell proliferation 1: Homo sapiens HeLa Cells   1
4. 1-(propoxymethyl)maleimide cell proliferation 1-(propoxymethyl)maleimide results in decreased cell proliferation 1: Homo sapiens Leukocytes | Cell Line, Tumor   1
5. 1-(propoxymethyl)maleimide cell proliferation 1-(propoxymethyl)maleimide results in decreased cell proliferation 1: Homo sapiens Kidney | Cell Line, Tumor   1
6. 1-(propoxymethyl)maleimide cell proliferation 1-(propoxymethyl)maleimide results in decreased cell proliferation 1: Homo sapiens Colon | Cell Line, Tumor   1
7. 1-(propoxymethyl)maleimide cell proliferation 1-(propoxymethyl)maleimide results in decreased cell proliferation 1: Homo sapiens Ovary | Cell Line, Tumor   1
8. 1-(propoxymethyl)maleimide cell proliferation 1-(propoxymethyl)maleimide results in decreased cell proliferation 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor   1
9. 1-(propoxymethyl)maleimide DNA catabolic process WRN [1-(propoxymethyl)maleimide results in decreased activity of WRN protein] which results in increased DNA catabolic process 1: Homo sapiens HeLa Cells   1
10. 1-(propoxymethyl)maleimide cell cycle WRN [1-(propoxymethyl)maleimide results in decreased activity of WRN protein] which results in decreased cell cycle 1: Homo sapiens HeLa Cells   1
11. 1-(propoxymethyl)maleimide cell proliferation telomestatin [1-(propoxymethyl)maleimide co-treated with telomestatin] results in decreased cell proliferation 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
12. 1-(propoxymethyl)maleimide cell proliferation KU0058948 [1-(propoxymethyl)maleimide co-treated with KU0058948] results in decreased cell proliferation 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
13. 1-(propoxymethyl)maleimide cell proliferation Topotecan [1-(propoxymethyl)maleimide co-treated with Topotecan] results in decreased cell proliferation 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
14. 1-(propoxymethyl)maleimide DNA catabolic process Topotecan [1-(propoxymethyl)maleimide co-treated with Topotecan] results in decreased DNA catabolic process 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
15. 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide protein kinase C signaling 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide results in decreased protein kinase C signaling 1: Homo sapiens Prostate | Cell Line, Tumor   1
16. 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide positive regulation of protein kinase C activity Tetradecanoylphorbol Acetate 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased positive regulation of protein kinase C activity] 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: WNT5A 1
17. 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide protein kinase C signaling 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide results in decreased protein kinase C signaling 1: Rattus norvegicus Pulmonary Alveoli | Epithelial Cells | Cells, Cultured   1
18. 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide triglyceride biosynthetic process triphenyl phosphate 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [triphenyl phosphate results in increased triglyceride biosynthetic process] 1: Mus musculus Serum   1
19. 2-hydroxyatorvastatin drug transmembrane transport 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid [5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid results in decreased drug transmembrane transport] which results in decreased import of 2-hydroxyatorvastatin 1: Homo sapiens Liver   1
20. 2-hydroxyatorvastatin drug transmembrane transport 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid [5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid results in decreased drug transmembrane transport] which results in increased abundance of 2-hydroxyatorvastatin 1: Homo sapiens Serum   1
21. 2-(omega-carboxyethyl)pyrrole positive regulation of angiogenesis 4-hydroxy-7-oxo-5-heptenoic acid lactone | Amines [[4-hydroxy-7-oxo-5-heptenoic acid lactone co-treated with Amines] results in increased chemical synthesis of 2-(omega-carboxyethyl)pyrrole analog] which results in increased positive regulation of angiogenesis     1
22. 2-(omega-carboxyethyl)pyrrole positive regulation of angiogenesis 2-(omega-carboxyethyl)pyrrole analog results in increased positive regulation of angiogenesis     1
23. 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one inhibitory postsynaptic potential HTR1B [3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one binds to and results in increased activity of HTR1B protein] which results in decreased inhibitory postsynaptic potential 1: Rattus norvegicus Periaqueductal Gray | Neurons   1
24. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione apoptotic process Paclitaxel | Sirolimus 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Paclitaxel co-treated with Sirolimus] results in increased apoptotic process] 1: Homo sapiens Mammary Glands, Human | Tumor Cells, Cultured
6 genes: APP | CASP8 | FAS | PARP1 | RPS6KB1 | TNF
1
25. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione cell death 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in increased cell death 1: Homo sapiens Mammary Glands, Human | Tumor Cells, Cultured   1
26. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione adipose tissue development GSK3B [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein] which results in decreased adipose tissue development 1: Mus musculus Mesenchymal Stromal Cells | Cell Line   1
27. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione apoptotic process Etoposide 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased apoptotic process] 1: Homo sapiens Hep G2 Cells
6 genes: APP | CASP8 | FAS | PARP1 | RPS6KB1 | TNF
1
28. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione apoptotic process Camptothecin 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Camptothecin results in increased apoptotic process] 1: Homo sapiens Hep G2 Cells
6 genes: APP | CASP8 | FAS | PARP1 | RPS6KB1 | TNF
1
29. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione apoptotic process GSK3B | Potassium 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Potassium deficiency results in increased activity of GSK3B protein] which results in increased apoptotic process] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured
6 genes: APP | CASP8 | FAS | PARP1 | RPS6KB1 | TNF
1
30. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione cell proliferation GSK3B [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein] which results in increased cell proliferation 1: Rattus norvegicus Neuroglia | Cell Line
4 genes: CTNNB1 | GSK3B | TNF | WNT3A
1
31. 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione cell proliferation Cisplatin 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Cisplatin results in decreased cell proliferation] 1: Mus musculus Organ of Corti | Cell Line
4 genes: CTNNB1 | GSK3B | TNF | WNT3A
1
32. 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester microtubule polymerization lipopolysaccharide, E coli O55-B5 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased microtubule polymerization] 1: Mus musculus Macrophages | Cell Line, Transformed   1
33. 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester nitric oxide biosynthetic process lipopolysaccharide, E coli O55-B5 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased nitric oxide biosynthetic process] 1: Mus musculus Macrophages | Cell Line, Transformed 1 gene: NOS2 1
34. 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester negative regulation of microtubule depolymerization lipopolysaccharide, E coli O55-B5 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester analog inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased negative regulation of microtubule depolymerization] 1: Mus musculus RAW 264.7 Cells   1
35. 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide positive regulation of cytosolic calcium ion concentration N-(1-azabicyclo(2.2.2)oct-3-yl)(5-(2-pyridyl)thiophene-2-carboxamide) [N-(1-azabicyclo(2.2.2)oct-3-yl)(5-(2-pyridyl)thiophene-2-carboxamide) co-treated with 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide] results in increased positive regulation of cytosolic calcium ion concentration 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured   1
36. 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine apoptotic process alvocidib alvocidib promotes the reaction [4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine results in increased apoptotic process] 1: Homo sapiens K562 Cells   1
37. 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine apoptotic process 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine results in increased apoptotic process 1: Homo sapiens Blood | Cell Line, Tumor   1
38. 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine apoptotic process alvocidib alvocidib promotes the reaction [4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine results in increased apoptotic process] 1: Homo sapiens Blood | Cell Line, Tumor   1
39. 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine apoptotic process alvocidib alvocidib promotes the reaction [4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine results in increased apoptotic process] 1: Mus musculus Bone Marrow | Cell Line   1
40. 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine apoptotic process 4-acetoxy-5-(1-(naphthyl))naphtho(2,3-b)pyrrolo(2,1-d)(1,4)oxazepine results in increased apoptotic process 1: Mus musculus Bone Marrow | Cell Line   1
41. 4-hydroxyatorvastatin drug transmembrane transport 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid [5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid results in decreased drug transmembrane transport] which results in decreased import of 4-hydroxyatorvastatin 1: Homo sapiens Liver   1
42. 4-hydroxyatorvastatin drug transmembrane transport 5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid [5-(N-(4-((4-ethylbenzyl)thio)phenyl)sulfamoyl)-2-methylbenzoic acid results in decreased drug transmembrane transport] which results in increased abundance of 4-hydroxyatorvastatin 1: Homo sapiens Serum   1
43. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride apoptotic process Hemin 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [Hemin results in increased apoptotic process] 1: Mus musculus Cell Line | Cerebral Cortex | Microvessels
5 genes: BAX | BCL2 | CASP3 | HMOX1 | PARP1
1
44. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride positive regulation of cell death Doxorubicin | rosiglitazone 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [[Doxorubicin co-treated with rosiglitazone] results in increased positive regulation of cell death] 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: HMGB1 1
45. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride positive regulation of cell death docetaxel | rosiglitazone 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [[docetaxel co-treated with rosiglitazone] results in increased positive regulation of cell death] 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: HMGB1 1
46. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride peptidyl-tyrosine modification Blood Glucose | Oxygen 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased peptidyl-tyrosine modification] 1: Rattus norvegicus Myocardium   1
47. 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) peptidyl-tyrosine modification Mevinphos | Peroxynitrous Acid 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Mevinphos promotes the reaction [Peroxynitrous Acid results in increased peptidyl-tyrosine modification]] 1: Rattus norvegicus Medulla Oblongata   1
48. 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) neurological system process involved in regulation of systemic arterial blood pressure Mevinphos 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Mevinphos affects neurological system process involved in regulation of systemic arterial blood pressure] 1: Rattus norvegicus Cardiovascular System   1
49. 5,15-diphenylporphyrin reactive oxygen species biosynthetic process Etoposide 5,15-diphenylporphyrin inhibits the reaction [Etoposide results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens MCF-7 Cells   1
50. 5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate activation of protein kinase C activity Glucose 5,21 - 12,17-dimetheneo-18H-dibenzo(i,o)pyrrolo(3,4-1)(1,8)diazacyclohexandecine-18,10(19H)dione,8((dimethylamino)methyl)-6,7,8,9,10,11-hexahydro,monomethanesulfonate inhibits the reaction [Glucose results in increased activation of protein kinase C activity] 1: Homo sapiens Human Umbilical Vein Endothelial Cells | Cells, Cultured   1
1–50 of 1,706 results.