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Chemical Rifampin

Name Rifampin
CAS Type 1 Name Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
Equivalent Terms Benemycin | Rifadin | Rifampicin | Rimactan | Rimactane | Tubocin
CAS Registry Number 13292-46-1
Definition A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
Structure Rifampin
Top Interacting
Genes
MeSH® ID D012293
External Links

Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 4 or More Rings Has associated genes Has associated diseases Has associated exposure references Rifamycins Has associated genes Has associated diseases Rifampin Has associated genes Has associated diseases
2. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Macrocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Lactams, Macrocyclic Has associated genes Has associated diseases Rifamycins Has associated genes Has associated diseases Rifampin Has associated genes Has associated diseases

Top ↑ Descendants

Rifampin Has associated genes Has associated diseases
  18,19-dihydrorifampicin
  21-(O-phosphoryl)rifampicin
  23-(O-(beta-glucopyranosyl))rifampicin
  23-(O-ribofuranosyl)rifampicin
  25-deacetylrifampicin
  25-desacetylrifapentine
  3-formyl-21-(O-phosphoryl)rifamycin SV
  3-formyl-23-(O-(beta-glucopyranosyl))rifamycin SV
  3-formyl-23-(O-ribofuranosyl)rifamycin SV
  CGP 43371
  CGS 24565
  cotrifazid
  dehydrorifampicin
  DMB-rifampicin
  isoniazid, pyrazinamide, rifampin drug combination Has associated diseases
  KSV21 compound
  Myrin P
  rifamazid
  rifampicin N-oxide
  rifapentine Has associated genes Has associated diseases
  Rifaprim
  rivicycline
  Sinerdol EH