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Chemical Rotenone

1–50 of 1,123 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1',2'-dihydrorotenone apoptotic process 1',2'-dihydrorotenone results in increased apoptotic process 1: Homo sapiens Plasma Cells
6 genes: AKT1 | E2F1 | MAPK1 | MAPK3 | RB1 | TP53
1
2. 1',2'-dihydrorotenone mitotic cell cycle arrest 1',2'-dihydrorotenone results in increased mitotic cell cycle arrest 1: Homo sapiens Plasma Cells
2 genes: CDKN1A | TP53
1
3. 1',2'-dihydrorotenone cell proliferation 1',2'-dihydrorotenone results in decreased cell proliferation 1: Homo sapiens Plasma Cells | Cell Line, Tumor
3 genes: AKT1 | CDK4 | TP53
1
4. 1',2'-dihydrorotenone mitotic cell cycle arrest 1',2'-dihydrorotenone results in increased mitotic cell cycle arrest 1: Homo sapiens Plasma Cells | Cell Line, Tumor
2 genes: CDKN1A | TP53
1
5. deguelin cell proliferation deguelin affects cell proliferation 1: Homo sapiens Prostate | Cell Line, Tumor
26 genes: AKT1 | BAK1 | BAX | BCL2 | BCL2L1 | CDK4 | CTNNB1 | CYP1A1 | EGFR | GSK3B | IGF1 | MAP2K1 | MKI67 | MYC | PDK1 | PRKDC | RAC1 | SMAD4 | SRC | STAT3 | TGFB1 | TNF | TP53 | VEGFA | WNT2B | WNT3A
1
6. deguelin cell proliferation NPM1 [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased cell proliferation 1: Homo sapiens Blood | Cell Line, Tumor
26 genes: AKT1 | BAK1 | BAX | BCL2 | BCL2L1 | CDK4 | CTNNB1 | CYP1A1 | EGFR | GSK3B | IGF1 | MAP2K1 | MKI67 | MYC | PDK1 | PRKDC | RAC1 | SMAD4 | SRC | STAT3 | TGFB1 | TNF | TP53 | VEGFA | WNT2B | WNT3A
1
7. deguelin apoptotic process NPM1 [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased apoptotic process 1: Homo sapiens Blood | Cell Line, Tumor
32 genes: AIFM1 | AKT1 | ATM | BAK1 | BAX | BCL2 | BCL2L1 | BIRC5 | BRCA1 | CASP3 | CASP6 | CASP7 | CASP8 | CD14 | CFLAR | CXCR4 | EGLN3 | ERN1 | IFNG | MAP2K7 | MAPK1 | MAPK3 | MCL1 | NFKBIA | PARP1 | RB1 | ROCK1 | RPS6KB1 | SFRP2 | TNF | TP53 | XIAP
1
8. deguelin cell differentiation NPM1 [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cell differentiation 1: Homo sapiens Blood | Cell Line, Tumor
18 genes: AKT1 | ANGPTL4 | CDH2 | CEBPA | CTNNB1 | EPAS1 | FRZB | GSK3B | HIF1A | IHH | KDR | MCL1 | RHOA | SFRP2 | TCF4 | TP53 | VEGFA | WNT11
1
9. deguelin positive regulation of cell death Piperonyl Butoxide Piperonyl Butoxide inhibits the reaction [deguelin results in increased positive regulation of cell death] 1: Mus musculus Hepatocytes | Cell Line, Tumor
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
10. deguelin mitochondrial electron transport, NADH to ubiquinone deguelin results in decreased mitochondrial electron transport, NADH to ubiquinone 1: Bos taurus Mitochondria, Heart | Submitochondrial Particles 1 gene: BDNF 1
11. deguelin mitochondrial electron transport, NADH to ubiquinone deguelin analog results in decreased mitochondrial electron transport, NADH to ubiquinone 1: Bos taurus Mitochondria, Heart | Submitochondrial Particles 1 gene: BDNF 1
12. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
13. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Mus musculus Hepatocytes | Cell Line, Tumor
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
14. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Mus musculus Neural Stem Cells | Cell Line, Tumor
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
15. deguelin positive regulation of cell death deguelin analog results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
16. deguelin positive regulation of cell death deguelin analog results in increased positive regulation of cell death 1: Mus musculus Hepatocytes | Cell Line, Tumor
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
17. deguelin positive regulation of cell death deguelin analog results in increased positive regulation of cell death 1: Mus musculus Neural Stem Cells | Cell Line, Tumor
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
18. deguelin insecticide catabolic process Piperonyl Butoxide [Piperonyl Butoxide results in decreased insecticide catabolic process] which results in increased susceptibility to deguelin 1: Mus musculus Hepatocytes | Cell Line, Tumor   1
19. deguelin cell migration deguelin results in decreased cell migration 1: Homo sapiens Bone and Bones | Cell Line, Tumor
16 genes: CD44 | CDH2 | CDH7 | CXCR4 | GSK3B | KDR | MMP2 | PLCG1 | RAC1 | RHOA | RPS6KB1 | SNAI1 | SRC | TGFB1 | VEGFA | WNT11
1
20. deguelin cell death deguelin results in increased cell death 1: Homo sapiens Bone and Bones | Cell Line, Tumor   1
21. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Homo sapiens Human Umbilical Vein Endothelial Cells
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
22. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Homo sapiens Bronchi | Epithelial Cells | Cell Line
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
23. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Homo sapiens Retinal Pigment Epithelium | Cell Line
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
24. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Homo sapiens Lung | Cell Line, Tumor
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
25. deguelin positive regulation of cell death deguelin results in increased positive regulation of cell death 1: Mus musculus Hippocampus | Neurons | Cell Line
4 genes: AIFM1 | CDKN1A | MTOR | PTGS2
1
26. deguelin cell proliferation deguelin results in decreased cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor
26 genes: AKT1 | BAK1 | BAX | BCL2 | BCL2L1 | CDK4 | CTNNB1 | CYP1A1 | EGFR | GSK3B | IGF1 | MAP2K1 | MKI67 | MYC | PDK1 | PRKDC | RAC1 | SMAD4 | SRC | STAT3 | TGFB1 | TNF | TP53 | VEGFA | WNT2B | WNT3A
2
27. deguelin cell migration deguelin results in decreased cell migration 1: Homo sapiens Lung | Cell Line, Tumor
16 genes: CD44 | CDH2 | CDH7 | CXCR4 | GSK3B | KDR | MMP2 | PLCG1 | RAC1 | RHOA | RPS6KB1 | SNAI1 | SRC | TGFB1 | VEGFA | WNT11
1
28. deguelin actin cytoskeleton reorganization deguelin results in increased actin cytoskeleton reorganization 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: RAC1 | RHOA
1
29. deguelin lamellipodium assembly deguelin results in decreased lamellipodium assembly 1: Homo sapiens Lung | Cell Line, Tumor 1 gene: RAC1 1
30. deguelin filopodium assembly deguelin results in decreased filopodium assembly 1: Homo sapiens Lung | Cell Line, Tumor   1
31. deguelin apoptotic process deguelin results in increased apoptotic process 1: Homo sapiens Lung | Cell Line, Tumor
32 genes: AIFM1 | AKT1 | ATM | BAK1 | BAX | BCL2 | BCL2L1 | BIRC5 | BRCA1 | CASP3 | CASP6 | CASP7 | CASP8 | CD14 | CFLAR | CXCR4 | EGLN3 | ERN1 | IFNG | MAP2K7 | MAPK1 | MAPK3 | MCL1 | NFKBIA | PARP1 | RB1 | ROCK1 | RPS6KB1 | SFRP2 | TNF | TP53 | XIAP
1
32. deguelin regulation of mitochondrial membrane potential deguelin affects regulation of mitochondrial membrane potential 1: Homo sapiens Lung | Cell Line, Tumor
4 genes: BAK1 | BAX | BCL2 | BCL2L1
1
33. deguelin calcium ion homeostasis deguelin affects calcium ion homeostasis 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: ADM | KDR
1
34. deguelin cell proliferation deguelin results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor
26 genes: AKT1 | BAK1 | BAX | BCL2 | BCL2L1 | CDK4 | CTNNB1 | CYP1A1 | EGFR | GSK3B | IGF1 | MAP2K1 | MKI67 | MYC | PDK1 | PRKDC | RAC1 | SMAD4 | SRC | STAT3 | TGFB1 | TNF | TP53 | VEGFA | WNT2B | WNT3A
1
35. deguelin cell migration deguelin results in decreased cell migration 1: Homo sapiens Pancreas | Cell Line, Tumor
16 genes: CD44 | CDH2 | CDH7 | CXCR4 | GSK3B | KDR | MMP2 | PLCG1 | RAC1 | RHOA | RPS6KB1 | SNAI1 | SRC | TGFB1 | VEGFA | WNT11
1
36. deguelin apoptotic process deguelin results in increased apoptotic process 1: Homo sapiens Pancreas | Cell Line, Tumor
32 genes: AIFM1 | AKT1 | ATM | BAK1 | BAX | BCL2 | BCL2L1 | BIRC5 | BRCA1 | CASP3 | CASP6 | CASP7 | CASP8 | CD14 | CFLAR | CXCR4 | EGLN3 | ERN1 | IFNG | MAP2K7 | MAPK1 | MAPK3 | MCL1 | NFKBIA | PARP1 | RB1 | ROCK1 | RPS6KB1 | SFRP2 | TNF | TP53 | XIAP
1
37. deguelin wound healing, spreading of cells deguelin results in decreased wound healing, spreading of cells 1: Homo sapiens Pancreas | Cell Line, Tumor
3 genes: CD44 | PTK2 | RHOA
1
38. deguelin cell death deguelin results in increased cell death 1: Homo sapiens Pancreas | Cell Line, Tumor   1
39. deguelin epithelial to mesenchymal transition TGFB1 deguelin inhibits the reaction [TGFB1 protein results in increased epithelial to mesenchymal transition] 1: Homo sapiens Pancreas | Cell Line, Tumor
7 genes: CTNNB1 | GSK3B | HIF1A | SNAI1 | STAT3 | TGFB1 | WNT11
1
40. deguelin wound healing, spreading of cells TGFB1 deguelin inhibits the reaction [TGFB1 protein results in increased wound healing, spreading of cells] 1: Homo sapiens Pancreas | Cell Line, Tumor
3 genes: CD44 | PTK2 | RHOA
1
41. mirabijalone E cell death mirabijalone E results in increased cell death 1: Homo sapiens HeLa Cells   1
42. mirabijalone E mitotic cell cycle arrest mirabijalone E results in increased mitotic cell cycle arrest 1: Homo sapiens Lung | Cell Line, Tumor   1
43. mirabijalone E apoptotic process mirabijalone E results in increased apoptotic process 1: Homo sapiens Lung | Cell Line, Tumor
3 genes: BAX | BCL2 | CASP3
1
44. mirabijalone E cell proliferation mirabijalone E results in decreased cell proliferation 1: Homo sapiens Lung | Cell Line, Tumor
2 genes: BAX | BCL2
1
45. Rotenone apoptotic process Rotenone results in increased apoptotic process 1: Rattus norvegicus PC12 Cells
150 genes: ADORA2A | AIFM1 | AKT1 | ALDOC | APAF1 | APP | ASAH2 | ATG5 | ATM | AVEN | BAD | BAG3 | BAX | BCL2 | BCL2L1 | BCL2L10 | BCL2L2 | BECN1 | BID | BIRC3 | BNIP3 | BRCA1 | BUB1B | CASP1 | CASP12 | CASP2 | CASP3 | CASP4 | CASP7 | CASP8 | CASP9 | CASR | CCAR1 | CCK | CCL6 | CD14 | CDCA7 | CEACAM6 | CHAC1 | CHEK1 | CRADD | CTSC | CYCS | DAPK1 | DDIT3 | DDIT4 | DFFB | DIABLO | EAT-3 | EBAG9 | ERCC2 | ERN1 | ERN2 | ERO1L | EVA1A | FAS | FKBP8 | GADD45A | GADD45G | GAPDH | GJA1 | GPX1 | HCAR2 | HINT1 | HMOX1 | HRAS | HRK | HTRA2 | IER3 | IFI27L2 | IFNG | IL1A | IL1B | JAK2 | KIF1B | LGALS16 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MAPT | MEF2D | MFN2 | MT3 | MTFR2 | MYD88 | NCF1 | NFKB1 | NFKBIA | NGB | NLRP3 | NR3C1 | NRADD | NTN1 | OPA1 | PARP1 | PDCD6IP | PIM2 | PLSCR3 | PMAIP1 | POLB | PPID | PPP1R15A | PPP2R2B | PRDX3 | PRKCB | PRKCD | PRKCE | PTEN | PURB | RBM25 | RFFL | RIPK1 | RPS3 | RPS6KB1 | SAP30BP | SEMA3A | SGK1 | SGPL1 | SIRT1 | SLK | SNCA | SQSTM1 | STK24 | SULF1 | TESK2 | TGFBR2 | TIAM1 | TIGAR | TNF | TNFAIP1 | TNFAIP3 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TP53 | TP53INP1 | TRAF1 | TRAF4 | TRAIP | TRIB3 | TRP53 | TSPO | UBE2D3 | UBE2Z | UNC5B | VDAC1 | XBP1
5
46. Rotenone response to oxidative stress dibutyldichlorotin Rotenone inhibits the reaction [dibutyldichlorotin results in increased response to oxidative stress] 1: Rattus norvegicus Thymus Gland | Mitochondria
73 genes: ADAR | AIFM1 | AKT1 | APOE | APP | BCL2 | BCL2L1 | CA3 | CAMK2G | CAT | COX1 | CYCS | CYTB | DDIT3 | EGFR | EPAS1 | ERCC2 | ERCC6 | GCLC | GCLM | GPX1 | GPX4 | GPX-6 | GSR | GSS | HMOX1 | IDH1 | JAK2 | KEAP1 | LRK-1 | LRRK2 | MMP2 | MMP9 | MPO | MT2 | MT3 | ND3 | NDUFA12 | NDUFA6 | NDUFB4 | NDUFS2 | NDUFS8 | NFKB1 | NQO1 | NUDT1 | PARK7 | PINK1 | PON2 | PPID | PPP1R15B | PRDX1 | PRDX2 | PRDX3 | PRDX6 | PRKCD | PRKN | PSMB5 | PTGS2 | RPS3 | SIRT1 | SKN-1 | SOD1 | SOD2 | SRXN1 | TFAM | TOR1A | TP53 | TRAP1 | TRP53 | TRPM2 | TXN2 | TXNIP | TXNRD1
1
47. Rotenone oxidation-reduction process dibutyldichlorotin Rotenone inhibits the reaction [dibutyldichlorotin results in increased oxidation-reduction process] 1: Rattus norvegicus Thymus Gland | Mitochondria
150 genes: AASS | ACAD9 | ACADSB | ACOX2 | ADH1C | AIFM1 | AIFM2 | AKR1B7 | AKR1D1 | ALDH1L2 | ALDH2 | ALDH8A1 | BLVRB | CAT | CBR3 | CBS | COX1 | CP | CRYZL1 | CYB5R1 | CYBA | CYBB | CYC1 | CYP11B1 | CYP11B2 | CYP19A1 | CYP1A | CYP27B1 | CYP27C1 | CYP-29A2 | CYP-34A9 | CYP-35A2 | CYP3A7 | CYTB | DBH | DCT | DCXR | DHCR7 | DHRS13 | DHRS2 | DHRS7 | DHRS7C | DLD | EHHADH | ERO1L | FASN | FTH1 | FTL1 | GAPDH | GPX1 | GPX4 | GPX-6 | GSR | GSTO1 | HADHB | HEPH | HMGCR | HMOX1 | HSD17B14 | HSD17B4 | HSD17B6 | HSD3B7 | IDH1 | IDH3A | IDH3B | IL4I1 | KDM4A | KDM5B | KIF1B | LDHA | LDHB | LDHD | MDH2 | MGST1 | MPO | MTHFD1 | MTRR | NCF1 | ND1 | ND2 | ND3 | ND6 | NDUFA10 | NDUFA12 | NDUFA3 | NDUFA4 | NDUFA5 | NDUFA6 | NDUFA8 | NDUFA9 | NDUFAB1 | NDUFB1 | NDUFB11 | NDUFB2 | NDUFB3 | NDUFB4 | NDUFB5 | NDUFB6 | NDUFB7 | NDUFB8 | NDUFS1 | NDUFS2 | NDUFS3 | NDUFS4 | NDUFS6 | NDUFS8 | NDUFV3 | NOS2 | NOS3 | NOX1 | NOX4 | NQO1 | PARK7 | PCBD1 | PDHA2 | PDHB | PDIA2 | PHGDH | PIR | PRDX1 | PRDX2 | PRDX3 | PRDX6 | PRODH2 | PTGS2 | RDH5 | RNLS | RRM2 | RSAD1 | SDHA | SESN2 | SNCA | SOD1 | SOD-1 | SOD2 | SQOR | SRXN1 | TH | TXN | TXN2 | TXNDC2 | TXNRD1 | TYRP1 | UQCRB | UQCRC1 | UQCRC2 | UQCRQ | XDH | YWHAH | YWHAZ
1
48. Rotenone apoptotic process dibutyldichlorotin Rotenone inhibits the reaction [dibutyldichlorotin results in increased apoptotic process] 1: Rattus norvegicus Thymus Gland | Cells
150 genes: ADORA2A | AIFM1 | AKT1 | ALDOC | APAF1 | APP | ASAH2 | ATG5 | ATM | AVEN | BAD | BAG3 | BAX | BCL2 | BCL2L1 | BCL2L10 | BCL2L2 | BECN1 | BID | BIRC3 | BNIP3 | BRCA1 | BUB1B | CASP1 | CASP12 | CASP2 | CASP3 | CASP4 | CASP7 | CASP8 | CASP9 | CASR | CCAR1 | CCK | CCL6 | CD14 | CDCA7 | CEACAM6 | CHAC1 | CHEK1 | CRADD | CTSC | CYCS | DAPK1 | DDIT3 | DDIT4 | DFFB | DIABLO | EAT-3 | EBAG9 | ERCC2 | ERN1 | ERN2 | ERO1L | EVA1A | FAS | FKBP8 | GADD45A | GADD45G | GAPDH | GJA1 | GPX1 | HCAR2 | HINT1 | HMOX1 | HRAS | HRK | HTRA2 | IER3 | IFI27L2 | IFNG | IL1A | IL1B | JAK2 | KIF1B | LGALS16 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MAPT | MEF2D | MFN2 | MT3 | MTFR2 | MYD88 | NCF1 | NFKB1 | NFKBIA | NGB | NLRP3 | NR3C1 | NRADD | NTN1 | OPA1 | PARP1 | PDCD6IP | PIM2 | PLSCR3 | PMAIP1 | POLB | PPID | PPP1R15A | PPP2R2B | PRDX3 | PRKCB | PRKCD | PRKCE | PTEN | PURB | RBM25 | RFFL | RIPK1 | RPS3 | RPS6KB1 | SAP30BP | SEMA3A | SGK1 | SGPL1 | SIRT1 | SLK | SNCA | SQSTM1 | STK24 | SULF1 | TESK2 | TGFBR2 | TIAM1 | TIGAR | TNF | TNFAIP1 | TNFAIP3 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TP53 | TP53INP1 | TRAF1 | TRAF4 | TRAIP | TRIB3 | TRP53 | TSPO | UBE2D3 | UBE2Z | UNC5B | VDAC1 | XBP1
1
49. Rotenone apoptotic process tributyltin Rotenone inhibits the reaction [tributyltin results in increased apoptotic process] 1: Rattus norvegicus Thymus Gland | Cells
150 genes: ADORA2A | AIFM1 | AKT1 | ALDOC | APAF1 | APP | ASAH2 | ATG5 | ATM | AVEN | BAD | BAG3 | BAX | BCL2 | BCL2L1 | BCL2L10 | BCL2L2 | BECN1 | BID | BIRC3 | BNIP3 | BRCA1 | BUB1B | CASP1 | CASP12 | CASP2 | CASP3 | CASP4 | CASP7 | CASP8 | CASP9 | CASR | CCAR1 | CCK | CCL6 | CD14 | CDCA7 | CEACAM6 | CHAC1 | CHEK1 | CRADD | CTSC | CYCS | DAPK1 | DDIT3 | DDIT4 | DFFB | DIABLO | EAT-3 | EBAG9 | ERCC2 | ERN1 | ERN2 | ERO1L | EVA1A | FAS | FKBP8 | GADD45A | GADD45G | GAPDH | GJA1 | GPX1 | HCAR2 | HINT1 | HMOX1 | HRAS | HRK | HTRA2 | IER3 | IFI27L2 | IFNG | IL1A | IL1B | JAK2 | KIF1B | LGALS16 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MAPT | MEF2D | MFN2 | MT3 | MTFR2 | MYD88 | NCF1 | NFKB1 | NFKBIA | NGB | NLRP3 | NR3C1 | NRADD | NTN1 | OPA1 | PARP1 | PDCD6IP | PIM2 | PLSCR3 | PMAIP1 | POLB | PPID | PPP1R15A | PPP2R2B | PRDX3 | PRKCB | PRKCD | PRKCE | PTEN | PURB | RBM25 | RFFL | RIPK1 | RPS3 | RPS6KB1 | SAP30BP | SEMA3A | SGK1 | SGPL1 | SIRT1 | SLK | SNCA | SQSTM1 | STK24 | SULF1 | TESK2 | TGFBR2 | TIAM1 | TIGAR | TNF | TNFAIP1 | TNFAIP3 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TP53 | TP53INP1 | TRAF1 | TRAF4 | TRAIP | TRIB3 | TRP53 | TSPO | UBE2D3 | UBE2Z | UNC5B | VDAC1 | XBP1
1
50. Rotenone apoptotic DNA fragmentation dibutyldichlorotin Rotenone inhibits the reaction [dibutyldichlorotin results in increased apoptotic DNA fragmentation] 1: Rattus norvegicus Thymus Gland | Cells
3 genes: CASP3 | DFFB | HMGB2
1
1–50 of 1,123 results.