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Chemical Saponins

1–50 of 672 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 23-epi-26-deoxyactein negative regulation of cell proliferation Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased negative regulation of cell proliferation] 1: Mus musculus Osteoblasts | Cell Line
2 genes: IL6 | TNF
1
2. 23-epi-26-deoxyactein positive regulation of cell death Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased positive regulation of cell death] 1: Mus musculus Osteoblasts | Cell Line   1
3. 23-epi-26-deoxyactein negative regulation of ATP biosynthetic process Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased negative regulation of ATP biosynthetic process] 1: Mus musculus Osteoblasts | Cell Line   1
4. 23-epi-26-deoxyactein positive regulation of cytosolic calcium ion concentration Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased positive regulation of cytosolic calcium ion concentration] 1: Mus musculus Osteoblasts | Cell Line   1
5. 23-epi-26-deoxyactein negative regulation of phosphatidylinositol 3-kinase activity Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased negative regulation of phosphatidylinositol 3-kinase activity] 1: Mus musculus Osteoblasts | Cell Line   1
6. 23-epi-26-deoxyactein positive regulation of cardiolipin metabolic process Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased positive regulation of cardiolipin metabolic process] 1: Mus musculus Osteoblasts | Cell Line   1
7. 23-epi-26-deoxyactein positive regulation of cardiolipin metabolic process Antimycin A | Cardiolipins 23-epi-26-deoxyactein inhibits the reaction [[Antimycin A results in increased positive regulation of cardiolipin metabolic process] which results in increased oxidation of Cardiolipins] 1: Mus musculus Osteoblasts | Cell Line   1
8. 23-epi-26-deoxyactein tyrosine metabolic process Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased tyrosine metabolic process] 1: Mus musculus Osteoblasts | Cell Line   1
9. 23-epi-26-deoxyactein tyrosine metabolic process Antimycin A | Nitro Compounds 23-epi-26-deoxyactein inhibits the reaction [[Antimycin A results in increased tyrosine metabolic process] which results in increased abundance of Nitro Compounds] 1: Mus musculus Osteoblasts | Cell Line   1
10. 23-epi-26-deoxyactein positive regulation of mitochondrial membrane potential Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in decreased positive regulation of mitochondrial membrane potential] 1: Mus musculus Osteoblasts | Cell Line   1
11. 23-epi-26-deoxyactein activation of protein kinase B activity Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in decreased activation of protein kinase B activity] 1: Mus musculus Osteoblasts | Cell Line   1
12. 23-epi-26-deoxyactein mitochondrial electron transport, cytochrome c to oxygen Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in decreased mitochondrial electron transport, cytochrome c to oxygen] 1: Mus musculus Osteoblasts | Cell Line   1
13. 23-epi-26-deoxyactein thioredoxin-disulfide reductase activity Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in decreased thioredoxin-disulfide reductase activity] 1: Mus musculus Osteoblasts | Cell Line   1
14. 23-epi-26-deoxyactein negative regulation of oxidoreductase activity Antimycin A | thioredoxin-disulfide reductase activity 23-epi-26-deoxyactein inhibits the reaction [[Antimycin A results in decreased thioredoxin-disulfide reductase activity] which results in increased negative regulation of oxidoreductase activity] 1: Mus musculus Osteoblasts | Cell Line   1
15. 23-epi-26-deoxyactein thioredoxin-disulfide reductase activity Antimycin A | negative regulation of oxidoreductase activity 23-epi-26-deoxyactein inhibits the reaction [[Antimycin A results in decreased thioredoxin-disulfide reductase activity] which results in increased negative regulation of oxidoreductase activity] 1: Mus musculus Osteoblasts | Cell Line   1
16. 23-epi-26-deoxyactein positive regulation of cell proliferation 23-epi-26-deoxyactein results in increased positive regulation of cell proliferation 1: Mus musculus Osteoblasts | Cell Line
2 genes: IL6 | TNF
1
17. 23-epi-26-deoxyactein positive regulation of alkaline phosphatase activity 23-epi-26-deoxyactein results in increased positive regulation of alkaline phosphatase activity 1: Mus musculus Osteoblasts | Cell Line   1
18. 23-epi-26-deoxyactein positive regulation of collagen biosynthetic process 23-epi-26-deoxyactein results in increased positive regulation of collagen biosynthetic process 1: Mus musculus Osteoblasts | Cell Line   1
19. 23-epi-26-deoxyactein positive regulation of biomineral tissue development 23-epi-26-deoxyactein results in increased positive regulation of biomineral tissue development 1: Mus musculus Osteoblasts | Cell Line   1
20. 23-epi-26-deoxyactein positive regulation of reactive oxygen species biosynthetic process Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Mus musculus Osteoblasts | Cell Line   1
21. 23-epi-26-deoxyactein positive regulation of superoxide anion generation Antimycin A 23-epi-26-deoxyactein inhibits the reaction [Antimycin A results in increased positive regulation of superoxide anion generation] 1: Mus musculus Osteoblasts | Cell Line   1
22. actein cell proliferation actein results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells
5 genes: CDK4 | CXCL1 | CYP1A1 | EPO | TSPO
1
23. actein cell proliferation actein results in decreased cell proliferation 1: Homo sapiens Mouth | Cell Line, Tumor
5 genes: CDK4 | CXCL1 | CYP1A1 | EPO | TSPO
1
24. actein cell proliferation actein results in decreased cell proliferation 1: Homo sapiens Breast | Cell Line, Tumor
5 genes: CDK4 | CXCL1 | CYP1A1 | EPO | TSPO
1
25. actein cell proliferation actein results in decreased cell proliferation 1: Homo sapiens Hep G2 Cells
5 genes: CDK4 | CXCL1 | CYP1A1 | EPO | TSPO
1
26. actein negative regulation of cell proliferation Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased negative regulation of cell proliferation] 1: Mus musculus Osteoblasts | Cell Line
4 genes: CDKN1A | CXCL1 | RB1 | SOD2
1
27. actein positive regulation of apoptotic process Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased positive regulation of apoptotic process] 1: Mus musculus Osteoblasts | Cell Line
4 genes: CDK4 | FAS | ID3 | TSPO
1
28. actein positive regulation of autophagy Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased positive regulation of autophagy] 1: Mus musculus Osteoblasts | Cell Line   1
29. actein positive regulation of cytosolic calcium ion concentration Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased positive regulation of cytosolic calcium ion concentration] 1: Mus musculus Osteoblasts | Cell Line
3 genes: C5 | CXCL1 | CXCL2
1
30. actein positive regulation of reactive oxygen species biosynthetic process Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Mus musculus Osteoblasts | Cell Line   1
31. actein membrane lipid catabolic process Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased membrane lipid catabolic process] 1: Mus musculus Osteoblasts | Cell Line   1
32. actein membrane lipid catabolic process Cardiolipins | Tetrachlorodibenzodioxin actein inhibits the reaction [[Tetrachlorodibenzodioxin results in increased membrane lipid catabolic process] which results in increased oxidation of Cardiolipins] 1: Mus musculus Osteoblasts | Cell Line   1
33. actein negative regulation of collagen biosynthetic process Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased negative regulation of collagen biosynthetic process] 1: Mus musculus Osteoblasts | Cell Line   1
34. actein negative regulation of biomineral tissue development Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in increased negative regulation of biomineral tissue development] 1: Mus musculus Osteoblasts | Cell Line   1
35. actein positive regulation of mitochondrial membrane potential Tetrachlorodibenzodioxin actein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased positive regulation of mitochondrial membrane potential] 1: Mus musculus Osteoblasts | Cell Line   1
36. actein negative regulation of cell proliferation actein results in increased negative regulation of cell proliferation 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor
4 genes: CDKN1A | CXCL1 | RB1 | SOD2
1
37. actein negative regulation of cell proliferation actein results in increased negative regulation of cell proliferation 1: Homo sapiens HT29 Cells
4 genes: CDKN1A | CXCL1 | RB1 | SOD2
1
38. actein response to simvastatin actein results in increased response to simvastatin 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor   1
39. actein response to simvastatin actein results in increased response to simvastatin 1: Homo sapiens HT29 Cells   1
40. actein negative regulation of cell proliferation Simvastatin actein promotes the reaction [Simvastatin results in increased negative regulation of cell proliferation] 1: Homo sapiens Mammary Glands, Human | Cell Line, Tumor
4 genes: CDKN1A | CXCL1 | RB1 | SOD2
1
41. actein negative regulation of cell proliferation Simvastatin actein promotes the reaction [Simvastatin results in increased negative regulation of cell proliferation] 1: Homo sapiens HT29 Cells
4 genes: CDKN1A | CXCL1 | RB1 | SOD2
1
42. alpha-chaconine positive regulation of nitric oxide biosynthetic process lipopolysaccharide, Escherichia coli O111 B4 alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of nitric oxide biosynthetic process] 1: Mus musculus Macrophages | Cell Line
5 genes: IL1B | IL6 | MAPK9 | PTGS2 | TNF
1
43. alpha-chaconine positive regulation of prostaglandin secretion lipopolysaccharide, Escherichia coli O111 B4 alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of prostaglandin secretion] 1: Mus musculus Macrophages | Cell Line
2 genes: IL1B | MAPK9
1
44. alpha-chaconine positive regulation of JNK cascade lipopolysaccharide, Escherichia coli O111 B4 alpha-chaconine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of JNK cascade] 1: Mus musculus Macrophages | Cell Line
3 genes: IL1B | MAP3K7 | TNF
1
45. alpha-chaconine positive regulation of JNK cascade IL6 | lipopolysaccharide, Escherichia coli O111 B4 alpha-chaconine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of JNK cascade] which results in increased expression of IL6 mRNA] 1: Mus musculus Macrophages | Cell Line
3 genes: IL1B | MAP3K7 | TNF
1
46. alpha-chaconine positive regulation of JNK cascade IL6 | lipopolysaccharide, Escherichia coli O111 B4 alpha-chaconine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of JNK cascade] which results in increased expression of IL6 protein] 1: Mus musculus Macrophages | Cell Line
3 genes: IL1B | MAP3K7 | TNF
1
47. alpha-chaconine positive regulation of JNK cascade lipopolysaccharide, Escherichia coli O111 B4 | TNF alpha-chaconine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of JNK cascade] which results in increased expression of TNF mRNA] 1: Mus musculus Macrophages | Cell Line
3 genes: IL1B | MAP3K7 | TNF
1
48. alpha-chaconine positive regulation of JNK cascade lipopolysaccharide, Escherichia coli O111 B4 | TNF alpha-chaconine inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 results in increased positive regulation of JNK cascade] which results in increased expression of TNF protein] 1: Mus musculus Macrophages | Cell Line
3 genes: IL1B | MAP3K7 | TNF
1
49. alpha-chaconine positive regulation of JNK cascade Lipopolysaccharides alpha-chaconine inhibits the reaction [Lipopolysaccharides results in increased positive regulation of JNK cascade] 1: Mus musculus Liver
3 genes: IL1B | MAP3K7 | TNF
1
50. alpha-chaconine cell death alpha-chaconine results in increased cell death 1: Homo sapiens MCF-7 Cells   1
1–50 of 672 results.