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Chemical Gonadal Steroid Hormones

These are exposure studies associated with the chemical and all of its children.

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1–15 of 15 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Vested A, et al. (2014). The objective of this study was to investigate whether maternal serum concentrations of polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) during pregnancy are associated with son's semen quality and reproductive hormone levels. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Mothers | Study subjects Denmark semen | serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Estradiol | FSHB | INHBB | LHB | PCB 180 | SHBG | Testosterone Details spermatogenesis | sperm motility
2. Turyk ME, et al. (2008). Consortium for the health assessment of Great Lakes sport fish consumption Polychlorinated biphenyls exposure, at levels comparable with those of the general U.S. population, was associated with increased thyroglobulin antibodies and increased T(4) in adult males. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls Study subjects United States serum | urine 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls | SERPINA7 | Testosterone | Thyrotropin | Thyroxine | Triiodothyronine Details immunoglobulin production | testosterone biosynthetic process | thyroid hormone metabolic process
3. Fénichel P, et al. (2012). The presence of unconjugated bisphenol A in all cord blood samples suggests placental transfer and fetal exposure. Androstenedione | bisphenol A | Estradiol | Estriol | Estrone | Testosterone Controls for disease:Cryptorchidism | Subjects with disease:Cryptorchidism | Infants or newborns France blood, cord Androstenedione | bisphenol A | Estradiol | Estriol | Estrone | Testosterone Details
4. Lassen TH, et al. (2014). We found that 98% of young men from the general population had detectable urinary levels of bisphenol A, and this was associated with altered levels of reproductive hormones and decreased motile spermatozoa. bisphenol A Study subjects Denmark serum | urine bisphenol A | Estradiol | LHB | Testosterone Details estradiol secretion | luteinizing hormone secretion | sperm motility | testosterone biosynthetic process | testosterone secretion
5. Omoruyi IM, et al. (2014). In this study, we investigated the presence of mutagens and chemicals exhibiting estrogenic activity in the daily diet of Nigerians, using in vitro assays. bisphenol A | Estradiol Nigeria water bisphenol A | Estradiol Details
6. Scinicariello F, et al. (2016). National Health and Nutrition Examination Survey (NHANES) We examined the association of bisphenol A (BPA), benzophenone-3 (BP-3), triclosan (TCS), and parabens with serum total testosterone (TT) levels in child and adolescent participants (ages 6-19 years) in the National Health and Nutrition Examination Survey (NHANES) 2011-2012. sex bisphenol A | oxybenzone | Parabens | Triclosan Children United States serum | urine bisphenol A | Cotinine | Creatinine | oxybenzone | Parabens | Testosterone | Triclosan Details testosterone biosynthetic process
7. Ajayi OO, et al. (2012). Results suggest that elevated serum heavy metals (cadmium and lead) and reduction of essential micronutrients (zinc, copper and vitamin E) may contribute to recurrent spontaneous abortion. Cadmium | Chromium | Copper | Iron | Lead | Magnesium | Manganese | Progesterone | Selenium | Tocopherols | Zinc Controls for disease:Abortion, Spontaneous | Subjects with disease:Abortion, Spontaneous | Pregnant females Nigeria serum Cadmium | Chromium | Copper | Iron | Lead | Magnesium | Manganese | Progesterone | Selenium | Tocopherols | Zinc Details
8. Ihde ES, et al. (2015). Endocrine disrupting environmental chemicals were detected in all children in the study, with measurable levels of 4-nonylphenol in nearly one third of subjects; this is the first known published study of 4-nonylphenol levels in American children; no associations were found between the urine levels of these chemicals tested and estrogen metabolites. Endocrine Disruptors Children United States urine 16-hydroxyestrone | 2-hydroxyestradiol | 2-hydroxyestrone | 2-methoxyestrone | 4-hydroxyestrone-4-methyl ether | 4-hydroxyestrone | 4-nonylphenol | bisphenol A | butylparaben | Estrogens | ethyl-p-hydroxybenzoate | methylparaben | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monoethyl phthalate | propylparaben | Triclosan Details estrogen metabolic process
9. Caldwell DJ, et al. (2010). The consistently large margins of exposure and margins of safety strongly suggest that prescribed and total estrogens that may potentially be present in drinking water in the United States are not causing adverse effects in residents, including sensitive subpopulations. Estrogens Children | Study subjects United States water, drinking Estradiol | Estriol | Estrogens | Estrone | Ethinyl Estradiol Details
10. Lopez-Espinosa MJ, et al. (2016). C8 Health Project (C8HP) We found serum perfluoroalkyl substances concentrations to be associated with lower levels of sex hormones and IGF-1 in children aged 6-9 years. Fluorocarbons | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children United States serum Estradiol | IGF1 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Testosterone Details estradiol secretion | gene expression | testosterone secretion
11. Goudarzi H, et al. (2017). Sapporo Cohort, Hokkaido Study on Environment and Child Health Our results indicate that prenatal exposure to perfluorinated chemicals is significantly associated with glucocorticoid and dehydroepiandrosterone levels in cord blood. tobacco Fluorocarbons | perfluorooctane sulfonic acid | perfluorooctanoic acid Fetuses | Infants or newborns | Pregnant females Japan blood, cord | serum Androstenedione | Cortisone | Dehydroepiandrosterone | Hydrocortisone | perfluorooctane sulfonic acid | perfluorooctanoic acid Details cortisol secretion | dehydroepiandrosterone secretion
12. Giwercman AH, et al. (2006). Gonadotropin levels and sex hormone-binding globulin seem to be affected by persistent organohalogen pollutant exposure, but the pattern of endocrine response is the subject of considerable geographic variation. Hydrocarbons, Halogenated Study subjects Greenland|Poland|
Sweden|Ukraine
serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Estradiol | FSHB | INHBB | LHB | Testosterone Details
13. Sancini A, et al. (2014). The correlation between the values of urinary nickel and plasma testosterone was found negative; we suggest that occupational exposure to low doses of nickel present in the urban environment is able to influence some lines of the hypothalamic-pituitary-gonadal axis in exposed workers. Nickel Workers Italy air, personal | plasma | urine Nickel | Testosterone Details
14. Toft G, et al. (2016). Environmental perfluorooctane sulfonate exposure was associated with steroid hormone and INSL3 concentrations in amniotic fluid, but was not associated with cryptorchidism or hypospadias in our study population. perfluorooctane sulfonic acid Pregnant females Denmark amniotic fluid 17-alpha-Hydroxyprogesterone | Androstenedione | Dehydroepiandrosterone Sulfate | Hydrocortisone | INSL3 | Progesterone | Testosterone Details Cryptorchidism | Hypospadias | regulation of gene expression | regulation of testosterone biosynthetic process
15. Sancini A, et al. (2014). Urinary 1-hydroxypyrene (a biomarker for exposure to polycyclic aromatic hydrocarbons) was measured in non-smoker male workers and was related to an increase in plasma estradiol; we believe that polycyclic aromatic hydrocarbons can interact with the hypothalamic-pituitary axis. Polycyclic Aromatic Hydrocarbons Workers Italy plasma | urine 1-hydroxypyrene | Estradiol Details
1–15 of 15 results.