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Chemical Silicon Dioxide

These are exposure studies associated with the chemical and all of its children.

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1–41 of 41 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Higuchi K, et al. (2012). This study showed that Mt. Sakurajima's volcanic activities increased the mortality of lung cancer and chronic obstructive pulmonary diseases in the Sakurajima-Tarumizu area, which has the largest amount of ashfall from the volcano in its vicinity. Air Pollutants | Silicon Dioxide Study subjects Japan Air Pollutants | Silicon Dioxide Details Death | Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Respiration Disorders
2. Rondeau V, et al. (2009). Aluminum Maladie d'Alzheimer (ALMA+) | Personnes Agees Quid Study (PAQUID) We found that the cognitive decline and the risk of dementia were higher for high consumption of Aluminum from drinking water. age Aluminum | Silicon Dioxide Study subjects France water, drinking, bottled | water, tap Aluminum | Silicon Dioxide Details Alzheimer Disease | cognition
3. Wu M, et al. (2010). These findings confirm the previously reported association between World Trade Center dust exposure and bronchiolar and interstitial lung disease. Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Workers United States lung Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Details Bronchiolitis | Fibrosis | Metaplasia | Pneumonia
4. Stamp LK, et al. (2015). We have replicated findings identifying dust exposure (grain and silica) and farm exposure as risk factors for granulomatosis with polyangiitis; we have shown activities associated with exposure to inhaled antigens (in particular those related to farming or gardening) may increase the risk of the disease. Antigens | Dust | Silicon Dioxide Controls for disease:Granulomatosis with Polyangiitis | Subjects with disease:Granulomatosis with Polyangiitis New Zealand Details Granulomatosis with Polyangiitis
5. Li P, et al. (2012). Third National Death Cause Survey (NDCS) Occupational agents represent an important cause of cancer, but indoor radon plays a relatively limited role in cancer causes in China. Arsenic | Asbestos | Benzene | benzidine | Chromates | Coke | Radon | Silicon Dioxide Study subjects China Details Leukemia | Lung Neoplasms | Mesothelioma | Urinary Bladder Neoplasms
6. Duncan KE, et al. (2010). In summary, we report here that water-elutriated, small size fractions of Libby amphibole and amosite (LA2.5 and AM2.5, respectively), which presumably penetrate deeper into the lung, are at least as potent in stimulating epithelial cell production of proinflammatory cytokines as unfractionated LA and AM. Furthermore, AM2.5 induced a 4- to 10-fold greater proinflammatory response compared with LA2.5. tobacco Asbestos, Amosite | Asbestos, Amphibole Study subjects United States Asbestos, Amosite | Asbestos, Amphibole Details inflammatory response | regulation of gene expression
7. Hiraku Y, et al. (2014). We demonstrate that 8-nitroguanine formation is associated with asbestos content in human lung tissues, raising the possibility that it might serve as a biomarker to evaluate asbestos exposure and carcinogenic risk. Asbestos, Amphibole | Asbestos Controls for disease:Mesothelioma, Malignant | Subjects with disease:Mesothelioma, Malignant Japan lung 8-nitroguanine | APEX1 | Asbestos, Amphibole | Asbestos, Serpentine Details
8. Isik R, et al. (2001). Diffuse malignant pleural mesothelioma patients with environmental asbestos exposure (vs. occupational exposure) showed more p21 (CDKN1A) immunopositivity; as well, patients with positive immunostaining had longer exposure times and were older than those having negative immunostaining. age Asbestos, Amphibole | Asbestos Subjects with disease:Mesothelioma, Malignant | Workers Turkey|United Kingdom biopsy CDKN1A Details
9. Vinikoor LC, et al. (2010). Agency for Toxic Substances and Disease Registry These data suggest that residents of Libby, Montana, who were children when the mine closed experienced some respiratory symptoms associated with asbestos-contaminated vermiculite exposure. Asbestos, Amphibole | vermiculite Study subjects United States Details Respiration Disorders
10. Paris C, et al. (2017). Asbestos-Related Diseases Cohort (ARDCo) | Asbestos-Related Diseases Cohort (ARDCo-Nut) Our findings provide support for an association between occupational exposure to asbestos and colon cancer incidence in men. Asbestos Study subjects France Details Colonic Neoplasms
11. Yan L, et al. (2002). Both exposure to asbestos and GSTM1 deficiency were related to lipid peroxidation (malondialdehyde levels) in workers, but the role of the former may be more important than that of the latter. genetics Asbestos Subjects with gene influence:GSTM1 | Workers China plasma Malondialdehyde Details
12. Berry G, et al. (2004). The excess relative risk of lung cancer from asbestos exposure is about three times higher in non-smokers than in smokers. tobacco Asbestos Study subjects Canada|China|
United Kingdom|United States
Details Lung Neoplasms
13. Pass HI, et al. (2005). Serum osteopontin levels can be used to distinguish persons with exposure to asbestos who do not have cancer from those with exposure to asbestos who have pleural mesothelioma. Asbestos Controls for disease:Asbestosis | Subjects with disease:Asbestosis | Controls for disease:Mesothelioma | Subjects with disease:Mesothelioma | Controls for disease:Pleural Neoplasms | Subjects with disease:Pleural Neoplasms | Study subjects | Workers United States serum SPP1 Details Asbestosis | Mesothelioma | Pleural Neoplasms
14. Maule MM, et al. (2007). This study provides strong evidence that asbestos pollution from an industrial source greatly increases mesothelioma risk. Asbestos Subjects with disease:Mesothelioma Italy Details Mesothelioma
15. Ferrante D, et al. (2007). Household exposure, as experienced by these asbestos-cement workers' wives, increases risk for pleural malignant mesothelioma but not for lung cancer. Asbestos Study subjects Italy Details Mesothelioma, Malignant | Pleural Neoplasms
16. Christensen BC, et al. (2008). Our data suggest that patient survival is associated with asbestos fiber burden in malignant pleural mesothelioma and is perhaps modified by susceptibility. sex Asbestos Subjects with disease:Mesothelioma, Malignant United States lung Asbestos Details Death
17. Rodríguez Portal JA, et al. (2009). These data attest to good diagnostic sensitivity and specificity of soluble mesothelin-related peptides for the diagnosis of malignant mesothelioma, and we also show that serum levels might serve as a marker of asbestos exposure. Asbestos Controls for disease:Mesothelioma, Malignant | Subjects with disease:Mesothelioma, Malignant | Subjects with disease:Pleural Diseases Spain serum MSLN Details Mesothelioma, Malignant
18. Mastrangelo G, et al. (2011). Osteopontin increased with increasing age and several aspects of asbestos exposure, without differences related to the presence of pleural plaques; the explanatory variables with a significant independent influence on OPN were length of exposure (positive correlation) and time elapsed since last exposure (positive correlation); however, since asbestos in lung tissue tends to wane over time, OPN should decrease (rather than increase) with time since last exposure, and, therefore, OPN cannot be a reliable biomarker of either exposure or the presence of pleural plaques. age Asbestos Workers Italy plasma SPP1 Details
19. Leivo-Korpela S, et al. (2012). The adipokine adipsin was associated with the degree of parenchymal fibrosis, impairment of pulmonary diffusing capacity, and with inflammatory activity in asbestos-exposed subjects, suggesting that adipsin may have a role in the pathogenesis or as a biomarker in asbestos-induced lung disease. Asbestos Controls for disease:Asbestosis | Subjects with disease:Asbestosis | Workers Finland plasma CFD Details Asbestosis | Pulmonary Fibrosis | cytokine production involved in inflammatory response | inflammatory response | interleukin-6 production
20. Filiberti R, et al. (2013). Multivariate analysis revealed significant predictors of increased soluble mesothelin-related peptide (including age greater than 57 years, current smoking, a positive anamnesis for cancer and for asbestos-related pleural lesions, and BMI less than 25); the degree of these associations is low, nevertheless they should be accounted for in the interpretation of mesothelin as a candidate marker predictive of mesothelioma. age | body mass index | disease | tobacco Asbestos Controls for disease:Neoplasms | Subjects with disease:Neoplasms | Subjects with disease:Pleural Diseases | Workers Italy serum MSLN Details
21. Andujar P, et al. (2013). These results emphasise distinct genetic alterations between asbestos-related thoracic tumours, but identify common potential susceptibility factors (i.e. single nucleotide polymorphisms in intron 7 of TP53); while genetic changes in non-small cell lung cancer are dominated by the effects of tobacco smoke, the increase of transversions in TP53 gene is consistent with a synergistic effect of asbestos. Asbestos Subjects with disease:Carcinoma, Non-Small-Cell Lung France lung Asbestos | TP53 Details
22. Kukkonen MK, et al. (2014). Our results support the hypothesis that the inflammasome is important in the development of fibrotic lung disease by associating the NLRP3 rs35829419 variant allele with increased risk of asbestos-related interstitial lung fibrosis, and the TGFB1 rs2241718 variant allele with decreased risk of asbestos-related visceral pleural fibrosis; polymorphisms in CARD8 and TIMP2 are proposed to modify the development and/or calcification of pleural thickenings. genetics Asbestos Subjects with gene influence:CARD8 | Subjects with gene influence:NLRP3 | Subjects with gene influence:TGFB1 | Subjects with gene influence:TIMP2 | Workers Finland Details Asbestosis | Calcinosis | Fibrosis | Occupational Diseases | Pleural Diseases
23. Comar M, et al. (2014). This study shows that in subjects from an hyperendemic area for malignant mesothelioma, the chemokine RANTES (CCL5) is associated with the exposure to asbestos fibres. Asbestos Controls for disease:Mesothelioma, Malignant | Subjects with disease:Mesothelioma, Malignant | Workers Italy serum CCL11 | CCL27 | CCL3 | CCL5 | CCL7 | CLEC11A | CSF1 | CSF3 | CXCL10 | CXCL12 | CXCL1 | CXCL8 | CXCL9 | HGF | IFNA2 | IFNG | IL12B | IL17A | IL1A | IL2RA | IL3 | IL4 | IL6 | LTA | MIF | NGF Details positive regulation of chemokine (C-C motif) ligand 5 production
24. Clemente M, et al. (2015). Participants affected by asbestos poisoning showed high occurrence rates of psychological health variables such as somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation, psychoticism, and global severity index. Asbestos Workers Spain Details Anxiety Disorders | Depressive Disorder | Obsessive-Compulsive Disorder | Paranoid Disorders | Phobic Disorders | Psychotic Disorders | Somatoform Disorders
25. Xu J, et al. (2015). The purpose of the present study was to determine whether the levels or detection rate of chemokine (C-C motif) ligand 3 (CCL3) in the serum are elevated in persons exposed to asbestos. Asbestos Study subjects Japan Details gene expression
26. Gilham C, et al. (2016). Our results confirm the major contribution of amosite to UK mesothelioma incidence and the substantial contribution of non-occupational exposure, particularly in women. sex Asbestos Subjects with disease:Mesothelioma, Malignant | Workers United Kingdom lung Asbestos, Amosite | Asbestos, Amphibole | Asbestos, Crocidolite | Asbestos, Serpentine Details Mesothelioma, Malignant | Pleural Neoplasms
27. Yoshida R, et al. (2001). We show that 8-oxodG levels in asbestos-exposed construction workers were higher (although not statistically significant), and that levels tended to correlate with duration of suspected exposure; these results suggest that even low-level asbestos exposure may induce oxidative stress. Asbestos Workers Japan urine 8-oxo-7-hydrodeoxyguanosine Details cellular response to oxidative stress
28. Alavanja MC, et al. (2004). Agricultural Health Study (AHS) We also found that four heavily used agricultural pesticides, including two herbicides (i.e., metolachlor and pendimethalin) and two insecticides (i.e., chlorpyrifos and diazinon), were associated with a significant excess lung cancer risk in the Agricultural Health Study cohort. Asbestos | Carbofuran | Chlorpyrifos | Diazinon | Dicamba | Dieldrin | Lead | metolachlor | pendimethalin | Tobacco Smoke Pollution Study subjects | Workers United States Details Agricultural Workers' Diseases | Lung Neoplasms
29. Valcin M, et al. (2007). Agricultural Health Study (AHS) Pesticides as well as grain and dust exposures were associated with chronic bronchitis among nonsmoking farm women. Asbestos | cyanazine | DDT | Dichlorvos | Gasoline | methyl bromide | Paraquat | Solvents Study subjects United States Details Agricultural Workers' Diseases | Bronchitis, Chronic
30. Inamura K, et al. (2014). In the present study, lung adenocarcinomas, for which asbestos-exposure and smoking-exposure data could be obtained, were examined for loss of heterozygosity and the p53 mutation. tobacco Asbestos | Tobacco Smoke Pollution Subjects with disease:Adenocarcinoma of lung Japan Details DNA metabolic process
31. Fano V, et al. (2004). Results from this case-control study indicate that the increased risk for lung cancer observed in an Italian area can partially be explained by tobacco smoke and occupational exposures. tobacco Asbestos | Tobacco Smoke Pollution Controls for disease:Lung Neoplasms | Subjects with disease:Lung Neoplasms | Workers Italy Details Lung Neoplasms
32. Alexander BH, et al. (2012). These results support the hypothesis that community exposure to asbestos-contaminated vermiculite originating from Libby, Montana, is associated with measurable effects based on radiographic evidence. Asbestos | vermiculite Study subjects United States Details Asbestosis
33. Noonan CW, et al. (2006). In a case-control study of Libby, Montana (a community with historical occupational and environmental exposure to asbestos-contaminated vermiculite), our preliminary findings support the hypothesis that asbestos exposure is associated with systemic autoimmune diseases. Asbestos | vermiculite Subjects with disease:Arthritis, Rheumatoid | Controls for disease:Autoimmune Diseases | Subjects with disease:Lupus Erythematosus, Systemic | Subjects with disease:Scleroderma, Systemic United States Details Autoimmune Diseases
34. Reid A, et al. (2005). In this cohort of former workers and residents of Wittenoom, asbestosis is not a mandatory precursor for asbestos related lung cancer. tobacco Asbestos, Crocidolite | Tobacco Smoke Pollution Study subjects | Workers Australia Details Lung Neoplasms
35. Baumann F, et al. (2011). Presence of serpentinite on roads is a major environmental risk factor for mesothelioma in New Caledonia. Asbestos, Serpentine Study subjects New Caledonia Asbestos, Serpentine Details Mesothelioma, Malignant
36. Biggeri A, et al. (2004). Despite the limitations of this ecological study, the results cohere with the results of toxicologic and observational studies and suggest an etiologic role for fluoro-edenite in nonmalignant respiratory diseases. fluor-edenite Study subjects Italy Details Death | Pleural Neoplasms | Pulmonary Disease, Chronic Obstructive
37. Putzu MG, et al. (2006). The occurrence of pleural mesothelioma cases, and the presence of fluoro-edenitic fibres in spontaneous sputum from 12 patients with chronic obstructive pulmonary disease, evidence the need to study the biological activity of fluoro-edenitic fibres and the implementation of epidemiological monitoring systems. fluor-edenite Subjects with disease:Pulmonary Disease, Chronic Obstructive Italy sputum fluor-edenite Details
38. Molla YB, et al. (2014). The precise trigger of podoconiosis (endemic non-filarial elephantiasis of the lower legs) is unknown, but epidemiological studies have linked the disease with barefoot exposure to red clay soils of volcanic origin; more quantities of smectite, mica, and quartz within the soil were associated with podoconiosis prevalence. mica | Quartz | Smectite Study subjects Ethiopia Details Elephantiasis
39. Naumova EN, et al. (2007). The study has demonstrated strong relationship between ash exposure and respiratory effects in children. Particulate Matter | Silicon Dioxide | Sulfur Children Ecuador Details Respiratory Tract Infections
40. Brown TP, et al. (2005). Data have been collected and used to develop a job-exposure matrix for United Kingdom industrial silica sand workers between 1978 and 2000. Silicon Dioxide Workers United Kingdom Silicon Dioxide Details
41. Rafeemanesh E, et al. (2014). Agate grinding workers in Iran are at increased risk for respiratory diseases, specifically for silicosis and chronic bronchitis; the disease is related to silica dust exposure, poor ventilation, and inappropriate personal protection. Silicon Dioxide Workers Iran, Islamic Republic of Details Asthma, Occupational | Bronchitis, Chronic | Silicosis
1–41 of 41 results.