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Chemical Somatostatin

Name Somatostatin
Equivalent Terms Cyclic Somatostatin | Somatofalk | Somatostatin 14 | Somatostatin-14 | Somatostatin, Cyclic | Somatotropin Release Inhibiting Factor | Somatotropin Release-Inhibiting Factor | Somatotropin Release Inhibiting Hormone | Somatotropin Release-Inhibiting Hormone | SRIH-14 | Stilamin
CAS Registry Number 51110-01-1
Definition A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.
Structure Somatostatin
Top Interacting
Genes
MeSH® ID D013004
External Links

Top ↑ Ancestors

1. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Hypothalamic Hormones Has associated genes Has associated diseases Pituitary Hormone Release Inhibiting Hormones Has associated genes Has associated diseases Somatostatin Has associated genes Has associated diseases
2. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormones Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Pancreatic Hormones Has associated genes Has associated diseases Somatostatin Has associated genes Has associated diseases
3. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Neuropeptides Has associated genes Has associated diseases Hypothalamic Hormones Has associated genes Has associated diseases Pituitary Hormone Release Inhibiting Hormones Has associated genes Has associated diseases Somatostatin Has associated genes Has associated diseases
4. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Hypothalamic Hormones Has associated genes Has associated diseases Pituitary Hormone Release Inhibiting Hormones Has associated genes Has associated diseases Somatostatin Has associated genes Has associated diseases
5. ChemicalsAmino Acids, Peptides, and Proteins Has associated genes Has associated diseases Has associated exposure references Peptides Has associated genes Has associated diseases Has associated exposure references Peptide Hormones Has associated genes Has associated diseases Has associated exposure references Pancreatic Hormones Has associated genes Has associated diseases Somatostatin Has associated genes Has associated diseases

Top ↑ Descendants

Somatostatin Has associated genes Has associated diseases
  188Re-MAG3-depreotide
  angiopeptin
  AOD 9604
  ASS 51
  ASS 52
  BIM 23003
  BIM 23034
  BIM 23052
  BIM 23120 Has associated genes Has associated diseases
  BIM 23206 Has associated genes Has associated diseases
  BIM 23268
  BIM 23926
  BIM-23A387
  BIM 23A760
  BIM-23A761
  CGP 15425
  CGP 23996
  CH 275
  CH 288
  cifetrelin
  CMDTPA-Tyr(3)-octreotate
  CTAP octapeptide Has associated genes Has associated diseases
  cyclo(7-aminoheptanoylphenylalanyl-tryptophyl-lysyl-benzylthreonyl)
  cyclo(7-aminoheptanoyl-phenylalanyl-tryptophyl-lysyl-threonyl)
  cyclo(aminoheptanoic acid-cyclo(cysteinyl-phenylalanyl-D-tryptophyl-lysyl-threonyl-cysteinyl))
  cyclo(beta-methyl-N-benzylglycyl-phenylalanyl-tryptophyl-lysyl-threonyl-phenylalanyl)
  cyclo(N-benzylglycyl-phenylalanyl-tryptophyl-lysyl-threonyl-phenylalanyl)
  cyclo(prolyl-thiomethyl-phenylalanyl-tryptophyl-lysyl-threonyl-phenylalanyl)
  cyclo(Pro-Phe-Trp-Lys-Thr-Phe)
  DC 32-87
  D,D-carbasomatostatin
  des-AA(1,4-6,11-13)-(4-nitrophenylalanyl(2)-cysteinyl(3)-tyrosyl(7)-4-aminophenylalanylcarbamoyl(8)-somatostatin-3-(2-naphthyl)-alaninamide
  dihydrosomatostatin
  gallium 68-DOTA-lanreotide
  JF-10-81
  Lan-7
  lanreotide Has associated genes Has associated diseases
  neuronostatin protein, rat
  pasireotide Has associated genes Has associated diseases
  pentetreotide
  Phe-Cys-Phe-Trp-Lys-Thr-Pen-Thr-NH2
  phenylalanyl-cyclo(cysteinyl-tyrosyltryptophyl-lysyl-threonyl-penicillamine)threoninamide
  phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide Has associated genes Has associated diseases
  PPSS3 protein, zebrafish
  preprosomatostatin (25-34)
  prosomatostatin
  prosomatostatin (29-92)
  prosomatostatin cryptic peptide
  PTR 3173
  PTR-3205
  RC 161
  San 201-456
  sms-D70
View node Somatostatin-28
  somatostatin 14, Tyr(11)-
  somatostatin 14, Tyr(7)-Gly(10)-
  somatostatin 20
  somatostatin-22
  somatostatin 25
  somatostatin 25-(1-9)
  somatostatin 26
  somatostatin 34
  somatostatin(3-6)
  somatostatin, 4-NH2-Phe(4)-Trp(8)-
  somatostatin, 5-fluoro-Trp(8)-
  somatostatin, 5-methoxy-Trp(8)-
  somatostatin(7-10)
  somatostatin (7-10), desamino-Trp
  somatostatin, Ala(2)-Trp(8)-Cys(14)-
  somatostatin, Ala(3,14)-
  somatostatin, Ala(5)-Orn(9)-
  somatostatin, Ala(5)-Trp(8)-
  somatostatin, azidonitrobenzoyl-Lys(4)-iodo-Tyr(11)-
  somatostatin, azidonitrobenzoyl-Lys(9)-iodo-Tyr(11)-
  somatostatin, cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)-
  somatostatin, cyclo(des-Ala(1)-des-Gly(2)-S-COMe-homo-CysNH2(3)-Trp(8)-des-Cys(14))-
  somatostatin, cyclo(Pro-dehydro-Phe-Trp-Lys-Thr-Phe)
  somatostatin, Cys(3)-
  somatostatin, de-Asn(5)-Trp(8)-Ser(13)-
  somatostatin, des-Ala(1)-
  somatostatin, des-Ala(1)-des-Gly(2)-Trp(8)-Asn(3,14)-
  somatostatin, des-amino acid(1,2,5)-Glu(7)-Trp(8)-IAmp(9)-m-I-Tyr(11)-hhLys(12)-
  somatostatin, des-Asn(5)-
  somatostatin, iodine-Tyr-
  somatostatin, iodo-Tyr(1)-
  somatostatin, N-Ac-des-Ala(1)-des-Gly(2)-4-Cl-Phe(6)-Trp(8)-
  somatostatin, nonapeptide-D-Trp(8)-
  somatostatin, N-Tyr(1)-
  somatostatin, octapeptide-Trp(8)-
  somatostatin, Phe(4)-
  somatostatin, Pro(2)-Met(13)-
  somatostatin, protamine zinc-
  somatostatin RC 102
  somatostatin, seleno-Cys(3,14)-Trp(8)-
  somatostatin, Ser(13)-
  somatostatin, Trp(8)-
  somatostatin, Trp(8)-Cys(14)-
  somatostatin, Tyr(11)-
  somatostatin, Val(1)-Trp(8)-
  sst1 protein, zebrafish
  technetium Tc 99m depreotide
  thrittene protein, human
  TT2-32
  vapreotide
  Woc4D
  Wy 40770
  Wy 40793
  Wy 41747