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Chemical Sphingolipids

1–50 of 165 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. CDw17 antigen cell proliferation oleyl 2-acetamido-2-deoxy-1-thioglucopyranoside [oleyl 2-acetamido-2-deoxy-1-thioglucopyranoside results in decreased cell proliferation] which results in increased abundance of CDw17 antigen 1: Homo sapiens Lung | Epithelial Cells | Cell Line, Tumor   1
2. Ceramides apoptotic process Ceramides analog results in increased apoptotic process 1: Homo sapiens U937 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
3. Ceramides apoptotic process Ceramides analog results in increased apoptotic process 1: Mus musculus Blood Cells | Tumor Cells, Cultured
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
4. Ceramides cell death Ceramides results in increased cell death 1: Rattus norvegicus Organ of Corti | Hair Cells, Auditory | Cells, Cultured   1
5. Ceramides apoptotic process Gentamicins Ceramides promotes the reaction [Gentamicins results in increased apoptotic process] 1: Rattus norvegicus Organ of Corti | Hair Cells, Auditory | Cells, Cultured
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
6. Ceramides apoptotic process Nitroprusside [Nitroprusside results in increased abundance of Ceramides] which results in increased apoptotic process 1: Mus musculus Osteoblasts | Cell Line
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
7. Ceramides apoptotic process Ceramides results in increased apoptotic process 1: Mus musculus Osteoblasts | Cell Line
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
8. Ceramides apoptotic process Raloxifene Hydrochloride Raloxifene Hydrochloride inhibits the reaction [Ceramides results in increased apoptotic process] 1: Mus musculus Osteoblasts | Cell Line
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
9. Ceramides apoptotic process Estradiol Estradiol inhibits the reaction [Ceramides results in increased apoptotic process] 1: Mus musculus Osteoblasts | Cell Line
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
10. Ceramides apoptotic process Ceramides results in increased apoptotic process 1: Homo sapiens HeLa Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
11. Ceramides apoptotic process Ceramides results in increased apoptotic process 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
12. Ceramides apoptotic process Calcitriol Calcitriol inhibits the reaction [Ceramides results in increased apoptotic process] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
13. Ceramides apoptotic process sphingosine 1-phosphate sphingosine 1-phosphate inhibits the reaction [Ceramides results in increased apoptotic process] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
14. Ceramides apoptotic process Calcitriol | N,N-dimethylsphingosine N,N-dimethylsphingosine inhibits the reaction [Calcitriol inhibits the reaction [Ceramides results in increased apoptotic process]] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
15. Ceramides apoptotic process Calcitriol | N,N-dimethylsphingosine | sphingosine 1-phosphate sphingosine 1-phosphate inhibits the reaction [N,N-dimethylsphingosine inhibits the reaction [Calcitriol inhibits the reaction [Ceramides results in increased apoptotic process]]] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
16. Ceramides apoptotic process Calcitriol | chelerythrine chelerythrine inhibits the reaction [Calcitriol inhibits the reaction [Ceramides results in increased apoptotic process]] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
17. Ceramides apoptotic process Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate inhibits the reaction [Ceramides results in increased apoptotic process] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
18. Ceramides apoptotic process N,N-dimethylsphingosine | Tetradecanoylphorbol Acetate N,N-dimethylsphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Ceramides results in increased apoptotic process]] 1: Homo sapiens HL-60 Cells
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
19. Ceramides cell cycle RB1 [Ceramides results in decreased phosphorylation of RB1 protein] which affects cell cycle 1: Homo sapiens Fibroblasts | Cell Line
6 genes: CDKN1A | MAPK1 | MAPK3 | PPP1CC | RB1 | TP53
1
20. Ceramides cell differentiation Calcitriol [Calcitriol results in increased cell differentiation] which affects the abundance of Ceramides 1: Homo sapiens HL-60 Cells
4 genes: ARNT | GSK3B | RAF1 | TP53
1
21. Ceramides apoptotic process Ceramides results in increased apoptotic process 1: Mus musculus Neuroglia | Cell Line, Tumor
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
22. Ceramides apoptotic process Cycloheximide Cycloheximide inhibits the reaction [Ceramides results in increased apoptotic process] 1: Mus musculus Neuroglia | Cell Line, Tumor
18 genes: APP | BAX | CASP3 | CASP7 | CYCS | FASLG | GPX1 | IFNG | MAP3K5 | MAPK1 | MAPK3 | NFKB1 | PPP2CA | PRKCA | RAF1 | RB1 | TNF | TP53
1
23. Ceramides positive regulation of apoptotic process N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | PTGS2 [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] inhibits the reaction [Ceramides affects positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
24. Ceramides positive regulation of p38MAPK cascade PTGS2 PTGS2 protein affects the reaction [Ceramides affects positive regulation of p38MAPK cascade] 1: Homo sapiens Ovary | Cell Line, Tumor 1 gene: MAP3K5 1
25. Ceramides positive regulation of apoptotic process Cytochalasin D Cytochalasin D inhibits the reaction [Ceramides affects positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
26. Ceramides positive regulation of apoptotic process Ceramides affects positive regulation of apoptotic process 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
27. Ceramides positive regulation of ERK1 and ERK2 cascade Ceramides affects positive regulation of ERK1 and ERK2 cascade 1: Homo sapiens Ovary | Cell Line, Tumor
4 genes: APP | MAPK3 | PRKCA | TNF
1
28. Ceramides positive regulation of p38MAPK cascade Ceramides affects positive regulation of p38MAPK cascade 1: Homo sapiens Ovary | Cell Line, Tumor 1 gene: MAP3K5 1
29. Ceramides positive regulation of ERK1 and ERK2 cascade 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ceramides affects positive regulation of ERK1 and ERK2 cascade] 1: Homo sapiens Ovary | Cell Line, Tumor
4 genes: APP | MAPK3 | PRKCA | TNF
1
30. Ceramides positive regulation of p38MAPK cascade 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ceramides affects positive regulation of p38MAPK cascade] 1: Homo sapiens Ovary | Cell Line, Tumor 1 gene: MAP3K5 1
31. Ceramides positive regulation of ERK1 and ERK2 cascade SB 203580 SB 203580 inhibits the reaction [Ceramides affects positive regulation of ERK1 and ERK2 cascade] 1: Homo sapiens Ovary | Cell Line, Tumor
4 genes: APP | MAPK3 | PRKCA | TNF
1
32. Ceramides positive regulation of p38MAPK cascade SB 203580 SB 203580 inhibits the reaction [Ceramides affects positive regulation of p38MAPK cascade] 1: Homo sapiens Ovary | Cell Line, Tumor 1 gene: MAP3K5 1
33. Ceramides positive regulation of apoptotic process SB 203580 SB 203580 inhibits the reaction [Ceramides affects positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
34. Ceramides positive regulation of apoptotic process 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ceramides affects positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
35. Ceramides positive regulation of apoptotic process resveratrol resveratrol promotes the reaction [Ceramides affects positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
36. Ceramides negative regulation of mitochondrial membrane potential Ceramides affects negative regulation of mitochondrial membrane potential 1: Homo sapiens Ovary | Cell Line, Tumor   1
37. Ceramides positive regulation of NF-kappaB transcription factor activity Ceramides results in increased positive regulation of NF-kappaB transcription factor activity 1: Homo sapiens MCF-7 Cells
5 genes: APP | NFKB1 | RELA | SPHK1 | TNF
1
38. Ceramides positive regulation of NF-kappaB transcription factor activity Ceramides results in increased positive regulation of NF-kappaB transcription factor activity 1: Homo sapiens U937 Cells
5 genes: APP | NFKB1 | RELA | SPHK1 | TNF
1
39. Ceramides positive regulation of NF-kappaB transcription factor activity SOD2 SOD2 protein inhibits the reaction [Ceramides results in increased positive regulation of NF-kappaB transcription factor activity] 1: Homo sapiens MCF-7 Cells
5 genes: APP | NFKB1 | RELA | SPHK1 | TNF
1
40. Ceramides glycosphingolipid biosynthetic process RV 538 [RV 538 results in decreased glycosphingolipid biosynthetic process] which results in increased abundance of Ceramides 1: Canis lupus familiaris Madin Darby Canine Kidney Cells 1 gene: UGCG 1
41. Ceramides positive regulation of apoptotic process Doxorubicin | SRSF1 SRSF1 protein promotes the reaction [Ceramides promotes the reaction [Doxorubicin results in increased positive regulation of apoptotic process]] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
42. Ceramides positive regulation of apoptotic process Doxorubicin | UGCG [UGCG protein results in decreased abundance of Ceramides] inhibits the reaction [Doxorubicin results in increased positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
43. Ceramides positive regulation of phosphoprotein phosphatase activity UGCG [UGCG protein results in decreased abundance of Ceramides] which results in decreased positive regulation of phosphoprotein phosphatase activity 1: Homo sapiens Ovary | Cell Line, Tumor 1 gene: PPP2CA 1
44. Ceramides positive regulation of apoptotic process fumonisin B1 [fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased positive regulation of apoptotic process 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
45. Ceramides regulation of RNA splicing Ceramides affects regulation of RNA splicing 1: Homo sapiens Ovary | Cell Line, Tumor   1
46. Ceramides positive regulation of DNA damage response, signal transduction by p53 class mediator Ceramides results in increased positive regulation of DNA damage response, signal transduction by p53 class mediator 1: Homo sapiens Ovary | Cell Line, Tumor   1
47. Ceramides positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator Ceramides results in increased positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1: Homo sapiens Ovary | Cell Line, Tumor   1
48. Ceramides positive regulation of apoptotic process Doxorubicin Ceramides promotes the reaction [Doxorubicin results in increased positive regulation of apoptotic process] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
49. Ceramides regulation of RNA splicing SRSF1 [Ceramides results in increased expression of and affects the localization of SRSF1 protein] which affects regulation of RNA splicing 1: Homo sapiens Ovary | Cell Line, Tumor   1
50. Ceramides positive regulation of apoptotic process calyculin A | Doxorubicin calyculin A inhibits the reaction [Ceramides promotes the reaction [Doxorubicin results in increased positive regulation of apoptotic process]] 1: Homo sapiens Ovary | Cell Line, Tumor
16 genes: BAX | CASP3 | FASLG | GSK3B | IFNG | MAP3K5 | MAPK8 | MAPK9 | PPP2CA | PRKN | PTGS2 | RELA | SMPD1 | SMPD2 | TNF | TP53
1
1–50 of 165 results.