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Chemical SRS-A

Name SRS-A
Equivalent Term Slow Reacting Substance of Anaphylaxis
Definition A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a 'slow-reacting substance of ANAPHYLAXIS' released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)
Top Interacting
Genes
MeSH® ID D013189
External Links

Top ↑ Ancestors

1. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references SRS-A Has associated genes Has associated diseases
2. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Essential Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references SRS-A Has associated genes Has associated diseases
3. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Inflammation Mediators Has associated genes Has associated diseases Has associated exposure references Autacoids Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references SRS-A Has associated genes Has associated diseases

Top ↑ Descendants

SRS-A Has associated genes Has associated diseases
  16-carboxy-17,18,19,20-tetranor-14,15-dihydro-N-acetylleukotriene E4
  16-carboxytetranordihyroleukotriene E4
  18-carboxy-19,20-dinor-N-acetylleukotriene E4
  20,20,20-trifluoroleukotriene E4
  2-norleukotriene D1
  4-hydroxy-5-((2-carboxyethyl)thio)-6-nonadecenoic acid
  5-hydroxy-6-mercapto-7,9,11,14-eicosatetraenoic acid
  9,10,11,12,14,15-hexahydroleukotriene C4
  BAY u9773 Has associated genes Has associated diseases
  CGP 34064A
  leukotriene C-2
  leukotriene C-3
  leukotriene C-4 sulfone
  leukotriene C-5
  leukotriene D-3
  leukotriene D-4 sulfone
View node Leukotriene E4 Has associated genes Has associated diseases
  leukotriene E-4 sulfone
  leukotriene F-4
  leukotriene F-4 sulfone
View node Leukotriene C4 Has associated genes Has associated diseases
View node Leukotriene D4 Has associated genes Has associated diseases
  N-acetylleukotriene D4