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Chemical Steroids

These are exposure studies associated with the chemical and all of its children.

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1–30 of 30 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Vested A, et al. (2014). The objective of this study was to investigate whether maternal serum concentrations of polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) during pregnancy are associated with son's semen quality and reproductive hormone levels. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Mothers | Study subjects Denmark semen | serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Estradiol | FSHB | INHBB | LHB | PCB 180 | SHBG | Testosterone Details spermatogenesis | sperm motility
2. Patel CJ, et al. (2012). National Health and Nutrition Examination Survey (NHANES) We screened for correlation between environmental factors and lipid levels, utilizing four independent surveys with information on 188 environmental factors from the Centers of Disease Control, National Health and Nutrition Examination Survey, collected between 1999 and 2006. age | body mass index | race | sex | socioeconomic status 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2,4,4',5-tetrachlorobiphenyl | 2-hydroxyfluorene | alpha-Tocopherol | Ascorbic Acid | beta Carotene | Cotinine | Cryptoxanthins | Fluorenes | Folic Acid | gamma-Tocopherol | Heptachlor Epoxide | Iron | lycopene | Mercury | nonachlor | oxychlordane | retinol palmitate | retinyl stearate | Vitamin A | Vitamin D Study subjects United States Details cholesterol metabolic process | triglyceride metabolic process
3. Palacios C, et al. (2012). In this group of overweight and obese individuals, 25-Hydroxyvitamin D was significantly related to vitamin D intake, sun exposure and vitamin D intake indices and percent body fat. body mass index | diet 25-hydroxyvitamin D | Vitamin D Study subjects Puerto Rico serum 25-hydroxyvitamin D | Vitamin D Details
4. Fénichel P, et al. (2012). The presence of unconjugated bisphenol A in all cord blood samples suggests placental transfer and fetal exposure. Androstenedione | bisphenol A | Estradiol | Estriol | Estrone | Testosterone Controls for disease:Cryptorchidism | Subjects with disease:Cryptorchidism | Infants or newborns France blood, cord Androstenedione | bisphenol A | Estradiol | Estriol | Estrone | Testosterone Details
5. Liu L, et al. (2017). In an experimental situation, ambient coarse particulate matter (and its biological constituents of endotoxin and beta-1,3-D-glucan) may influence neural biomarker levels that reflect perturbations of blood-brain barrier integrity and systemic stress response in volunteers. beta-1,3-D-glucan | Endotoxins | Particulate Matter Study subjects Canada blood | urine Hydrocortisone | S100B | UCHL1 | Vanilmandelic Acid Details
6. Yang JH, et al. (2012). National Health and Nutrition Examination Survey (NHANES) The current study suggests that the background exposure to some organochlorine pesticides leads to vitamin D deficiency in humans. beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | Hexachlorobenzene | nonachlor | oxychlordane Controls for disease:Chronic Disease | Subjects with disease:Chronic Disease | Study subjects United States serum 25-hydroxyvitamin D | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | Hexachlorobenzene | nonachlor | oxychlordane Details Vitamin D Deficiency
7. Lassen TH, et al. (2014). We found that 98% of young men from the general population had detectable urinary levels of bisphenol A, and this was associated with altered levels of reproductive hormones and decreased motile spermatozoa. bisphenol A Study subjects Denmark serum | urine bisphenol A | Estradiol | LHB | Testosterone Details estradiol secretion | luteinizing hormone secretion | sperm motility | testosterone biosynthetic process | testosterone secretion
8. Omoruyi IM, et al. (2014). In this study, we investigated the presence of mutagens and chemicals exhibiting estrogenic activity in the daily diet of Nigerians, using in vitro assays. bisphenol A | Estradiol Nigeria water bisphenol A | Estradiol Details
9. Scinicariello F, et al. (2016). National Health and Nutrition Examination Survey (NHANES) We examined the association of bisphenol A (BPA), benzophenone-3 (BP-3), triclosan (TCS), and parabens with serum total testosterone (TT) levels in child and adolescent participants (ages 6-19 years) in the National Health and Nutrition Examination Survey (NHANES) 2011-2012. sex bisphenol A | oxybenzone | Parabens | Triclosan Children United States serum | urine bisphenol A | Cotinine | Creatinine | oxybenzone | Parabens | Testosterone | Triclosan Details testosterone biosynthetic process
10. Ajayi OO, et al. (2012). Results suggest that elevated serum heavy metals (cadmium and lead) and reduction of essential micronutrients (zinc, copper and vitamin E) may contribute to recurrent spontaneous abortion. Cadmium | Chromium | Copper | Iron | Lead | Magnesium | Manganese | Progesterone | Selenium | Tocopherols | Zinc Controls for disease:Abortion, Spontaneous | Subjects with disease:Abortion, Spontaneous | Pregnant females Nigeria serum Cadmium | Chromium | Copper | Iron | Lead | Magnesium | Manganese | Progesterone | Selenium | Tocopherols | Zinc Details
11. Tornhammar P, et al. (2014). Our objective was to assess the link between season of birth, neonatal 25-hydroxyvitamin D3, and adult cardiovascular disease; we report higher neonatal 25(OH)D3 associated with higher levels of cholesterol (in women), fasting insulin, and triglyceride, and with a higher risk of overweight at 35 years of age, but not with other adult cardiovascular disease risk factors. sex Calcifediol | Vitamin D Infants or newborns | Study subjects Sweden blood | serum Calcifediol | Cholesterol | Insulin | Triglycerides Details Obesity | Weight Gain | cholesterol homeostasis | regulation of insulin secretion | triglyceride homeostasis
12. Ihde ES, et al. (2015). Endocrine disrupting environmental chemicals were detected in all children in the study, with measurable levels of 4-nonylphenol in nearly one third of subjects; this is the first known published study of 4-nonylphenol levels in American children; no associations were found between the urine levels of these chemicals tested and estrogen metabolites. Endocrine Disruptors Children United States urine 16-hydroxyestrone | 2-hydroxyestradiol | 2-hydroxyestrone | 2-methoxyestrone | 4-hydroxyestrone-4-methyl ether | 4-hydroxyestrone | 4-nonylphenol | bisphenol A | butylparaben | Estrogens | ethyl-p-hydroxybenzoate | methylparaben | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monoethyl phthalate | propylparaben | Triclosan Details estrogen metabolic process
13. Caldwell DJ, et al. (2010). The consistently large margins of exposure and margins of safety strongly suggest that prescribed and total estrogens that may potentially be present in drinking water in the United States are not causing adverse effects in residents, including sensitive subpopulations. Estrogens Children | Study subjects United States water, drinking Estradiol | Estriol | Estrogens | Estrone | Ethinyl Estradiol Details
14. Lopez-Espinosa MJ, et al. (2016). C8 Health Project (C8HP) We found serum perfluoroalkyl substances concentrations to be associated with lower levels of sex hormones and IGF-1 in children aged 6-9 years. Fluorocarbons | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children United States serum Estradiol | IGF1 | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Testosterone Details estradiol secretion | gene expression | testosterone secretion
15. Goudarzi H, et al. (2017). Sapporo Cohort, Hokkaido Study on Environment and Child Health Our results indicate that prenatal exposure to perfluorinated chemicals is significantly associated with glucocorticoid and dehydroepiandrosterone levels in cord blood. tobacco Fluorocarbons | perfluorooctane sulfonic acid | perfluorooctanoic acid Fetuses | Infants or newborns | Pregnant females Japan blood, cord | serum Androstenedione | Cortisone | Dehydroepiandrosterone | Hydrocortisone | perfluorooctane sulfonic acid | perfluorooctanoic acid Details cortisol secretion | dehydroepiandrosterone secretion
16. Giwercman AH, et al. (2006). Gonadotropin levels and sex hormone-binding globulin seem to be affected by persistent organohalogen pollutant exposure, but the pattern of endocrine response is the subject of considerable geographic variation. Hydrocarbons, Halogenated Study subjects Greenland|Poland|
Sweden|Ukraine
serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Estradiol | FSHB | INHBB | LHB | Testosterone Details
17. Peters JL, et al. (2012). Normative Aging Study (NAS) Blood lead level may be related with cardiovascular disease in healthy older men through its association with tumor necrosis factor receptor-2 (TNFRSF1B); in addition, the magnitude of the association of blood lead level with TNFRSF1B level increased with age in the study population. genetics Lead Study subjects United States blood | patella | serum | tibia Cholesterol | Cholesterol, HDL | Cholesterol, LDL | CRP | ICAM1 | IL6 | Lead | TNFRSF1B | Triglycerides Details Cardiovascular Diseases
18. Harari F, et al. (2016). Our study suggests that lithium exposure through drinking water during pregnancy may impair the calcium homeostasis (particularly vitamin D): blood lithium was inversely associated with 25-hydroxyvitamin D3, positively associated with serum magnesium, and inversely associated with urinary calcium and magnesium. diet Lithium Pregnant females | Study subjects Argentina blood | plasma | serum | urine | water, drinking Arsenic | Boron | Calcifediol | Calcium | Cesium | Lithium | Magnesium | Phosphorus Details calcium ion homeostasis
19. Sancini A, et al. (2014). The correlation between the values of urinary nickel and plasma testosterone was found negative; we suggest that occupational exposure to low doses of nickel present in the urban environment is able to influence some lines of the hypothalamic-pituitary-gonadal axis in exposed workers. Nickel Workers Italy air, personal | plasma | urine Nickel | Testosterone Details
20. Toft G, et al. (2016). Environmental perfluorooctane sulfonate exposure was associated with steroid hormone and INSL3 concentrations in amniotic fluid, but was not associated with cryptorchidism or hypospadias in our study population. perfluorooctane sulfonic acid Pregnant females Denmark amniotic fluid 17-alpha-Hydroxyprogesterone | Androstenedione | Dehydroepiandrosterone Sulfate | Hydrocortisone | INSL3 | Progesterone | Testosterone Details Cryptorchidism | Hypospadias | regulation of gene expression | regulation of testosterone biosynthetic process
21. Sancini A, et al. (2014). Urinary 1-hydroxypyrene (a biomarker for exposure to polycyclic aromatic hydrocarbons) was measured in non-smoker male workers and was related to an increase in plasma estradiol; we believe that polycyclic aromatic hydrocarbons can interact with the hypothalamic-pituitary axis. Polycyclic Aromatic Hydrocarbons Workers Italy plasma | urine 1-hydroxypyrene | Estradiol Details
22. Ganji V, et al. (2010). National Health and Nutrition Examination Survey (NHANES) In this large population based study, likelihood of having depression in persons with vitamin D deficiency is significantly higher compared to those with vitamin D sufficiency. body mass index | race | sex | socioeconomic status Vitamin D Controls for disease:Depressive Disorder | Subjects with disease:Depressive Disorder | Controls for disease:Depressive Disorder, Major | Subjects with disease:Depressive Disorder, Major | Subjects with disease:Obesity | Subjects with disease:Overweight | Study subjects United States serum Vitamin D Details
23. Massa J, et al. (2015). Osteoporotic Fractures in Men Study (MrOS) Among older men, low levels of total serum 25-hydroxyvitamin D are associated with poorer sleep including short sleep duration and lower sleep efficiency. Vitamin D Study subjects United States serum 25-hydroxyvitamin D Details Dyssomnias | sleep
24. Graham KA, et al. (2015). While there was no significant difference in mean 25-hydroxyvitamin D levels between schizophrenic and healthy subjects, we did find that lower vitamin D levels in schizophrenia subjects were associated with more severe negative symptoms and overall cognitive deficits. Vitamin D Controls for disease:Schizophrenia | Subjects with disease:Schizophrenia United States serum 25-hydroxyvitamin D Details Cognition Disorders | cognition
25. Lee DM, et al. (2014). European Male Ageing Study (EMAS) We report that lower 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels independently predicted all-cause mortality in middle-aged and older European men, while associations with cancer mortality were only observed among men with very low levels of 25-hydroxyvitamin D. Vitamin D Controls for disease:Death | Subjects with disease:Death | Subjects with disease:Neoplasms Belgium|Estonia|
Hungary|Italy|
Poland|Spain|
Sweden|United Kingdom
serum 1,25-dihydroxyvitamin D | 25-hydroxyvitamin D Details Death
26. McGrath JJ, et al. (2010). Both low and high concentrations of neonatal vitamin D are associated with increased risk of schizophrenia, and it is feasible that this exposure could contribute to a sizeable proportion of cases in Denmark. Vitamin D Controls for disease:Schizophrenia | Subjects with disease:Schizophrenia Denmark blood Calcifediol Details Schizophrenia
27. Cieslak K, et al. (2014). This study demonstrates a relationship of low vitamin D levels with increased cellular aging in females, and also demonstrates potential sex-specific profiles among schizophrenia cases with hypovitaminosis. sex Vitamin D Subjects with disease:Schizophrenia | Subjects with disease:Vitamin D Deficiency United States serum Vitamin D Details Anhedonia | Developmental Disabilities | Psychotic Disorders | Schizophrenia | Social Communication Disorder | aggressive behavior | cell aging | regulation of telomere maintenance via telomere lengthening | social behavior
28. Mao X, et al. (2014). We describe associations among basic characteristics, seasons, and diseases with serum levels of 25-hydroxyvitamin D in patients and note that 25(OH)D3 levels are low while 25(OH)D2 levels are high among patients with lung diseases, dyskinesias, and coronary heart disease, and participants with diabetes and cerebral infarction have higher 25(OH)D3 serum concentrations compared with lung disease patients. age | disease Vitamin D Subjects with disease:Cerebral Infarction | Subjects with disease:Coronary Disease | Subjects with disease:Diabetes Mellitus | Subjects with disease:Dyskinesias | Subjects with disease:Hypertension | Subjects with disease:Lung Diseases | Study subjects China serum 25-Hydroxyvitamin D 2 | 25-hydroxyvitamin D | Calcifediol Details
29. Majumdar V, et al. (2015). The relationship between vitamin D deficiency and stroke was cross-sectionally evaluated in the high-risk Asian Indian population, and we conclude that hypertension partly explains the association between low 25-hydroxyvitamin D levels and ischemic stroke. disease Vitamin D Controls for disease:Cerebral Infarction | Subjects with disease:Cerebral Infarction | Subjects with disease:Hypertension India serum 25-hydroxyvitamin D Details Cerebral Infarction
30. Gracious BL, et al. (2012). Vitamin D deficiency and insufficiency are both highly prevalent in adolescents with severe mental illness and warrants further investigation as to whether vitamin D deficiency is a mediator of illness severity, result of illness severity, or both. Vitamin D Controls for disease:Vitamin D Deficiency | Subjects with disease:Vitamin D Deficiency United States serum 25-hydroxyvitamin D Details Mental Disorders
1–30 of 30 results.