These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Kelishadi R, et al. (2013).||Childhood and Adolescence Surveillance and Prevention of Adult Noncommunicable disease (CASPIAN)||Cadmium levels were considerably high in adolescents with and without metabolic syndrome, and levels had positive but nonsignificant association with some cardiometabolic risk factors and liver enzymes; the associations did not reach statistical significance, perhaps due to high levels of cadmium in both groups or because of the young age of participants.||Cadmium||Children | Controls for disease:Metabolic Syndrome | Subjects with disease:Metabolic Syndrome||Iran, Islamic Republic of||blood | serum||Blood Glucose | Cadmium | Cholesterol, HDL | Cholesterol, LDL | GOT1 | GPT | Triglycerides||Details||Metabolic Syndrome|
|2.||Tornhammar P, et al. (2014).||Our objective was to assess the link between season of birth, neonatal 25-hydroxyvitamin D3, and adult cardiovascular disease; we report higher neonatal 25(OH)D3 associated with higher levels of cholesterol (in women), fasting insulin, and triglyceride, and with a higher risk of overweight at 35 years of age, but not with other adult cardiovascular disease risk factors.||sex||Calcifediol | Vitamin D||Infants or newborns | Study subjects||Sweden||blood | serum||Calcifediol | Cholesterol | Insulin | Triglycerides||Details||Obesity | Weight Gain | cholesterol homeostasis | regulation of insulin secretion | triglyceride homeostasis|
|3.||Peters JL, et al. (2012).||Normative Aging Study (NAS)||Blood lead level may be related with cardiovascular disease in healthy older men through its association with tumor necrosis factor receptor-2 (TNFRSF1B); in addition, the magnitude of the association of blood lead level with TNFRSF1B level increased with age in the study population.||genetics||Lead||Study subjects||United States||blood | patella | serum | tibia||Cholesterol | Cholesterol, HDL | Cholesterol, LDL | CRP | ICAM1 | IL6 | Lead | TNFRSF1B | Triglycerides||Details||Cardiovascular Diseases|
|4.||Harari F, et al. (2016).||Our study suggests that lithium exposure through drinking water during pregnancy may impair the calcium homeostasis (particularly vitamin D): blood lithium was inversely associated with 25-hydroxyvitamin D3, positively associated with serum magnesium, and inversely associated with urinary calcium and magnesium.||diet||Lithium||Pregnant females | Study subjects||Argentina||blood | plasma | serum | urine | water, drinking||Arsenic | Boron | Calcifediol | Calcium | Cesium | Lithium | Magnesium | Phosphorus||Details||calcium ion homeostasis|
|5.||McGrath JJ, et al. (2010).||Both low and high concentrations of neonatal vitamin D are associated with increased risk of schizophrenia, and it is feasible that this exposure could contribute to a sizeable proportion of cases in Denmark.||Vitamin D||Controls for disease:Schizophrenia | Subjects with disease:Schizophrenia||Denmark||blood||Calcifediol||Details||Schizophrenia|
|6.||Mao X, et al. (2014).||We describe associations among basic characteristics, seasons, and diseases with serum levels of 25-hydroxyvitamin D in patients and note that 25(OH)D3 levels are low while 25(OH)D2 levels are high among patients with lung diseases, dyskinesias, and coronary heart disease, and participants with diabetes and cerebral infarction have higher 25(OH)D3 serum concentrations compared with lung disease patients.||age | disease||Vitamin D||Subjects with disease:Cerebral Infarction | Subjects with disease:Coronary Disease | Subjects with disease:Diabetes Mellitus | Subjects with disease:Dyskinesias | Subjects with disease:Hypertension | Subjects with disease:Lung Diseases | Study subjects||China||serum||25-Hydroxyvitamin D 2 | 25-hydroxyvitamin D | Calcifediol||Details|