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Chemical Teniposide

Name Teniposide
CAS Type 1 Name Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-((4,6-O-(2-thienylmethylene)-beta-D-glucopyranosyl)oxy)-, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
Equivalent Terms Bristol Myers Brand of Teniposide | Bristol-Myers Brand of Teniposide | Bristol Myers Squibb Brand of Teniposide | Bristol-Myers Squibb Brand of Teniposide | Demethyl Epipodophyllotoxin Thenylidine Glucoside | NSC122819 | NSC 122819 | NSC-122819 | Teniposide, (5a alpha,9 alpha(S*))-Isomer | VM26 | VM 26 | VM-26 | Vumon
CAS Registry Number 29767-20-2
Definition A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle.
Structure Teniposide
Top Interacting
Genes
MeSH® ID D013713
External Links

Top ↑ Ancestors

ChemicalsCarbohydrates Has associated genes Has associated diseases Has associated exposure references Glycosides Has associated genes Has associated diseases Has associated exposure references Glucosides Has associated genes Has associated diseases Teniposide Has associated genes Has associated diseases

Top ↑ Descendants

Teniposide Has associated genes Has associated diseases
  ALL-82 protocol Has associated diseases
  ALL-85 protocol
  BBVDD protocol
  CAV-T protocol
  CHVmP-VB protocol
  CHVP protocol
  CHVP regimen
  CTVP protocol Has associated diseases
  CVAP-B protocol
  CVP protocol 2
  DHACT protocol
  LLA-IV-AR protocol
  LTPP protocol
  MATCOP regimen
  MBVP protocol
  MV26PD protocol
  MVLP protocol
  OPEC-D protocol
  OPEC protocol 1
  TOTAL-XII protocol
  VAMA protocol
  VCD protocol
  VCE protocol
  VIM3 protocol
  VMM protocol